Detailed information for compound 75491

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 626.831 | Formula: C28H46N6O6S2
  • H donors: 6 H acceptors: 6 LogP: -0.85 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 3
  • SMILES: NCCCC[C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCSC)Cc1ccccc1)C(C)C)C)S)N
  • InChi: 1S/C28H46N6O6S2/c1-17(2)22(34(3)27(38)26(41)33-23(35)19(30)12-8-9-14-29)25(37)32-21(16-18-10-6-5-7-11-18)24(36)31-20(28(39)40)13-15-42-4/h5-7,10-11,17,19-22,26,41H,8-9,12-16,29-30H2,1-4H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20+,21+,22+,26+/m1/s1
  • InChiKey: JCTKMPHTQNNOEU-RZFRIWOHSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Protein farnesyltransferase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium yoelii Prenyltransferase and squalene oxidase repeat, putative Get druggable targets OG5_128081 All targets in OG5_128081
Cryptosporidium parvum protein geranyl-geranyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Theileria parva farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium knowlesi protein farnesyltransferase subunit beta, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Giardia lamblia Prenyltransferase Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium berghei protein farnesyltransferase subunit beta, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma cruzi protein farnesyltransferase, putative Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma mansoni protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Babesia bovis prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Echinococcus granulosus protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Candida albicans similar to S. cerevisiae RAM1 (YDL090C) beta subunit of farnesyl transferase (Ram1p+Ram2p), involved in prenylation of RAS prote Get druggable targets OG5_128081 All targets in OG5_128081
Echinococcus multilocularis protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma brucei protein farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania mexicana farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania donovani farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma japonicum ko:K05954 farnesyltransferase, CAAX box, beta [EC:2.5.1.58], putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium knowlesi conserved Plasmodium protein, unknown function Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium vivax conserved Plasmodium protein, unknown function Get druggable targets OG5_128081 All targets in OG5_128081
Cryptosporidium hominis chain B, structure of fpt bound to ggpp Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania major farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Neospora caninum protein farnesyltranstransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma brucei gambiense protein farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma cruzi protein farnesyltransferase, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium vivax farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania infantum farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein Get druggable targets OG5_128081 All targets in OG5_128081
Candida albicans similar to S. cerevisiae RAM1 (YDL090C) beta subunit of farnesyl transferase (Ram1p+Ram2p), involved in prenylation of RAS prote Get druggable targets OG5_128081 All targets in OG5_128081
Entamoeba histolytica protein farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania braziliensis farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Schistosoma mansoni hypothetical protein 0.0459 0.2411 1
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0035 0.0368
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0035 0.0124 0.044
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0234 0.1198 0.4966
Leishmania major P-type H -ATPase, putative 0.004 0.0154 0.2766
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0067 0.0299 0.8598
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0126 0.0514
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.003 0.0095
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis glutathione S transferase 0.0025 0.0074 0.0171
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0068 0.102
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0076 0.0345 0.1425
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0032 0.0472
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0066 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0057 0.013
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0066 0.0544
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0033 0.0113 0.046
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0081 0.047
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0025 0.0072 0.11
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus granulosus glutathione S transferase 0.002 0.0043 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Echinococcus multilocularis nervana 2 0.0194 0.098 0.2326
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0032 0.0111
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0032 0.0111
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0081 0.0328
Brugia malayi nuclear receptor RXR 0.0024 0.0066 0.0544
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0025 0.0072 0.0165
Trichomonas vaginalis pc-MYB2, putative 0.0027 0.0085 0.2113
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0186
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Plasmodium vivax calcium-transporting ATPase, putative 0.0076 0.0345 1
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0022 0.0095
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.021 0.1413
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0028 0.0086 0.2135
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0025 0.0072 0.0294
Brugia malayi nuclear receptor RXR 0.0027 0.0081 0.0672
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0028 0.0086 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0113 0.2962
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.007 0.0315 0.1305
Giardia lamblia Rab geranylgeranyltransferase 0.0025 0.0072 0.04
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0066 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0142 0.3854
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0022 0.0196
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0033 0.0113 0.046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0067 0.0299 0.1234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.021 0.1413
Leishmania major calcium-transporting ATPase, putative 0.007 0.0315 0.5997
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.007 0.0315 0.1305
Echinococcus granulosus nervana 2 0.0234 0.1198 0.4963
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0068 0.0236
Trichomonas vaginalis C-MYB, putative 0.0027 0.0085 0.2113
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0025 0.0074 0.0305
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0032 0.0305
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0593
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0032 0.0305
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0515 0.0697
Brugia malayi ecdysone receptor 0.0024 0.0066 0.0544
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0703
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0025 0.0072 0.1665
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.021 0.0868
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0079
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0299 0.8605
Schistosoma mansoni glutathione-S-transferase 0.0025 0.0074 0.0305
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.021 0.1739
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0245 0.4578
Leishmania major aminophospholipid translocase, putative 0.0016 0.0022 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Brugia malayi ecdysteroid receptor 0.0051 0.021 0.1739
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0033 0.0113 0.2924
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.021 0.0494
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0016 0.0022 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0417 0.1721
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0526 0.2774 1
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0025 0.0072 0.0288
Trypanosoma brucei calcium-transporting ATPase, putative 0.0016 0.0022 0.0095
Leishmania major farnesyltransferase beta subunit 0.0067 0.0299 0.5679
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0032 0.013
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0054
Echinococcus granulosus nervana 2 0.0194 0.098 0.4059
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0045 0.0178 0.1176
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0027 0.0102
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0069 0.031 0.5902
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0126 0.0515
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Brugia malayi calcium ATPase 0.0035 0.0124 0.1028
Schistosoma mansoni transmemberane protein 0.0234 0.1198 0.4966
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.2845
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0081 0.0672
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0035 0.0124 0.1028
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0185 0.0932 0.2213
Echinococcus multilocularis dna polymerase kappa 0.0057 0.0245 0.0577
Schistosoma mansoni zinc finger protein 0.0015 0.0017 0.0069
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0016 0.0022 0.0035
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0066 0.0357
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1709
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0579 0.0787
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0417 0.0986
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.007 0.0315 0.1305
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0304 0.8733
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0032 0.0312
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0245 0.0319
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0057 0.0227
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.021 0.0868
Loa Loa (eye worm) calcium ATPase 0.0041 0.0158 0.1034
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1867 1 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0016 0.0022 0.0095
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.0197
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0015 0.0017 0.0053
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0032 0.0109
Schistosoma mansoni cpg binding protein 0.0036 0.0131 0.0539
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0032 0.0462
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0016 0.0022 0.0046
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0015 0.0017 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0035 0.0368
Plasmodium falciparum calcium-transporting ATPase 0.007 0.0315 0.9078
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Echinococcus granulosus cation transporting atpase worm 0.0015 0.0017 0.0061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0299 0.8605
Schistosoma mansoni type V p-type atpase isoform 0.0016 0.0022 0.0087
Echinococcus multilocularis cation transporting atpase worm 0.0015 0.0017 0.0035
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0025 0.0072 0.11
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0421
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0194 0.098 0.4059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0081 0.0334
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0032 0.0305
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0025 0.0157
Schistosoma mansoni DNA polymerase eta 0.0107 0.0514 0.2131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0033 0.0113 0.0264
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0126 0.0295
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0027 0.0108
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0066 0.0544
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0072 0.11
Giardia lamblia GTOR 0.0018 0.0032 0.0111
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0018 0.0035 0.0558
Brugia malayi MH2 domain containing protein 0.0119 0.0577 0.4776
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0035 0.0368
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0261 0.1074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0025 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0515 0.0697
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0158 0.4326
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0067 0.0299 0.5679
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.021 0.0494
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0421
Brugia malayi Na,K-ATPase alpha subunit 0.019 0.0962 0.7971
Giardia lamblia DINP protein human, muc B family 0.0057 0.0245 0.1666
Plasmodium falciparum glutathione S-transferase 0.0025 0.0074 0.1745
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0025 0.0237
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0069 0.031 0.5902
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0134
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0236 0.1207 0.8712
Schistosoma mansoni ATPase 0.0069 0.031 0.1285
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0067 0.0299 0.1072
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0001 0.0011
Giardia lamblia DNA damage repair protein 0.0018 0.0032 0.0113
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0066 0.027
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.019 0.1269
Brugia malayi glutathione transferase 0.0186 0.0941 0.7791
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0067 0.0299 0.0707
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Schistosoma mansoni cation-transporting atpase worm 0.0015 0.0017 0.0067
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.007 0.0315 0.1299
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0022 0.0196
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0081 0.0334
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0143
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.021 0.0494
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0515 0.0697
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.021 0.0862
Schistosoma mansoni zinc finger protein 0.0021 0.005 0.0204
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0045 0.0178 0.1471
Brugia malayi ImpB/MucB/SamB family protein 0.0107 0.0514 0.4259
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0015 0.0017 0.0053
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0579 0.0787
Loa Loa (eye worm) RecQ helicase 0.0022 0.0057 0.0292
Loa Loa (eye worm) E1-E2 ATPase 0.004 0.0154 0.1007
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus multilocularis glutathione S transferase 0.002 0.0043 0.0097
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0126 0.0521
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.007 0.0315 0.9083
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0045 0.0209
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0066 0.027
Trypanosoma brucei ISWI complex protein 0.0015 0.0017 0.001
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0466
Treponema pallidum NADH oxidase 0.0016 0.0025 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0066 0.0264
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0016 0.0022 0.0095
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0032 0.0305
Echinococcus multilocularis copper transporting ATPase 1 0.0015 0.0017 0.0035
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0057 0.0245 0.6947
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0066 0.0543
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.8934
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0033 0.0113 0.0264
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0076 0.0345 0.0817
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0033 0.0113 0.2924
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0045 0.0178 0.3231
Echinococcus multilocularis chromobox protein 1 0.0068 0.0304 0.0717
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0067 0.0299 0.8605
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0703
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.021 0.1739
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0076 0.0345 0.1425
Brugia malayi calcium ATPase 0.0035 0.0128 0.1059
Brugia malayi CHD4 protein 0.0015 0.0017 0.014
Schistosoma mansoni GST class-mu 0.0025 0.0074 0.0305
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0792 0.4205 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0025 0.0072 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0032 0.0472
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0033 0.0113 0.0264
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.1931
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0016 0.0022 0.0144
Leishmania major hypothetical protein, conserved 0.0033 0.0113 0.1931
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0066 0.0543
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0066 0.0544
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0268 0.1383 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0032 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.021 0.1413
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0025 0.0072 0.0165
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0032 0.0312
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0113 0.1931
Trichomonas vaginalis cation-transporting ATPase, putative 0.004 0.0154 0.4218
Leishmania major DNA polymerase eta, putative 0.0107 0.0514 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1867 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0032 0.0312
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.021 0.1748
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0018 0.0035 0.0292
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0068 0.0156
Schistosoma mansoni ATPase 0.0069 0.031 0.1285
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0035 0.0368
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0066 0.0151
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0184 0.0927 0.0912
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0417 0.1726
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0015 0.0017 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0087
Brugia malayi Membrane calcium atpase protein 3 0.007 0.0315 0.261
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0081 0.0672
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0157
Brugia malayi hypothetical protein 0.0035 0.0126 0.1046
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.4963
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0025 0.0074 0.0171
Plasmodium falciparum phosphodiesterase gamma, putative 0.0033 0.0113 0.2924
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0157
Echinococcus granulosus Na:K ATPase alpha subunit 0.0185 0.0932 0.3861
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0067 0.0299 0.8605
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0049 0.0201 0.5605
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0057 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0018 0.0035 0.0134
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0016 0.0022 0.0046
Brugia malayi nuclear hormone receptor 0.0024 0.0066 0.0544
Trypanosoma brucei trypanothione reductase 0.0047 0.019 0.3486
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni DNA helicase recq1 0.0022 0.0057 0.0233
Loa Loa (eye worm) hypothetical protein 0.0143 0.071 0.5071
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0057 0.126
Plasmodium falciparum geranylgeranyltransferase, putative 0.0018 0.0035 0.0558
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0076 0.0345 1
Brugia malayi nuclear receptor NHR-67 0.0024 0.0066 0.0544
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0033 0.0113 0.046
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.1931
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1341 0.7163 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) hypothetical protein 0.0037 0.0139 0.0893
Schistosoma mansoni nuclear hormone receptor 0.0051 0.021 0.0868
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Brugia malayi E1-E2 ATPase family protein 0.0015 0.0017 0.014
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0025 0.0157
Brugia malayi nuclear receptor NHR-88 0.0024 0.0066 0.0544
Onchocerca volvulus 0.0032 0.0111 0.0918
Echinococcus multilocularis glutathione S transferase 0.002 0.0043 0.0097
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Plasmodium vivax phosphodiesterase gamma, putative 0.0033 0.0113 0.2924
Leishmania major DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0025 0.0205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0417 0.1721
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0401
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0158 0.079 0.1082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus granulosus nervana 2 0.0234 0.1198 0.4963
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0067 0.0299 0.8605
Brugia malayi steroid hormone receptor 0.0051 0.021 0.1739
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0067 0.0299 0.8598
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0025 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0185 0.0932 0.6697
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0025 0.0072 0.1709
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.021 0.1739
Trypanosoma brucei P-type H+-ATPase, putative 0.004 0.0154 0.2766
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0068 0.0272
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0245 0.4578
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Loa Loa (eye worm) DR-78 0.0024 0.0066 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0345 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.021 0.1748
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0066 0.0151
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.007 0.0315 0.1129
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0144
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.021 0.0862
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0025 0.0157
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0245 0.0577
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0165 0.0825 0.5913
Toxoplasma gondii P-type ATPase PMA1 0.004 0.0154 0.0549
Leishmania major hypothetical protein, conserved 0.0015 0.0017 0.001
Leishmania major calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0032 0.0309
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0015 0.0017 0.0053
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0016 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0594
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.021 0.1739
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0066 0.0264
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.021 0.0494
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0018 0.0035 0.0608
Entamoeba histolytica hypothetical protein 0.0024 0.0068 0.1544
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.021 0.1413
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.2845
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0041 0.0159 0.4331
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0025 0.0157
Schistosoma mansoni thyroid hormone receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0304 0.2098
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0032 0.0305
Brugia malayi tailless protein 0.0024 0.0066 0.0544
Plasmodium vivax glutathione reductase, putative 0.0047 0.019 0.5277
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.021 0.1739
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0076 0.0345 1
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Toxoplasma gondii P-type ATPase4, putative 0.0076 0.0345 0.1238
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0268 0.1383 0.5734
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0526 0.2774 0.3858
Loa Loa (eye worm) hypothetical protein 0.0017 0.003 0.0099
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus granulosus chromobox protein 1 0.0068 0.0304 0.1251
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0066 0.0544
Brugia malayi SET domain containing protein 0.0012 0.0001 0.0006
Echinococcus multilocularis chromobox protein 1 0.0068 0.0304 0.0717
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.021 0.0494
Schistosoma mansoni copper ABC transporter ATPase 0.0015 0.0017 0.0067
Brugia malayi PHD-finger family protein 0.0026 0.0078 0.0645
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.002 0.0043 0.0837
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0025 0.0237
Brugia malayi hypothetical protein 0.0024 0.0066 0.0544
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0143
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0032 0.0109
Echinococcus multilocularis nervana 2 0.0234 0.1198 0.2845
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0515 0.0697
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0261 0.0616
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0113 0.0936
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0158 0.1314
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0069 0.031 0.2148
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0069 0.031 0.5902
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0068 0.102
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0016 0.0022 0.0035
Echinococcus multilocularis glutathione S transferase 0.0025 0.0074 0.0171
Onchocerca volvulus 0.0025 0.0072 0.0592
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.019 0.3486
Schistosoma mansoni atpase class VI type 11c 0.0012 0.0002 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0022 0.0196
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0069 0.031 0.5902
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0032 0.0305
Onchocerca volvulus 0.002 0.0043 0.0352
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0066 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.021 0.1413
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus granulosus dna polymerase kappa 0.0057 0.0245 0.1006
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Schistosoma mansoni cpg binding protein 0.0036 0.0131 0.0539
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Giardia lamblia Rab geranylgeranyltransferase 0.0018 0.0035 0.0134
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.003 0.0067
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0466
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0032 0.0312
Trichomonas vaginalis MYB3r3, putative 0.0027 0.0085 0.2113
Echinococcus multilocularis glutathione S-transferase 0.0025 0.0074 0.0171
Brugia malayi nuclear receptor NHR-88 0.0051 0.021 0.1739
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.007 0.0315 0.261
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0033 0.0113 0.0936
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.003 0.0123
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0015 0.0017 0.0067
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0068 0.056
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0069
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0027 0.0108
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0016 0.0022 0.0095
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0018 0.0035 0.0292
Echinococcus granulosus phospholipid transporting ATPase IF 0.0016 0.0022 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0066 0.0264
Loa Loa (eye worm) hypothetical protein 0.0129 0.0634 0.4515
Loa Loa (eye worm) hypothetical protein 0.004 0.0151 0.0984
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.021 0.0868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0025 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.021 0.1739
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0025 0.0011
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0268 0.1383 0.5737
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0515 0.0697
Brugia malayi Heterochromatin protein 1 0.0068 0.0304 0.2514
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.021 0.1739
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0515 0.0697
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0093
Schistosoma mansoni thyroid hormone receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.019 0.0962 0.6919
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0526 0.2774 0.2762
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0417 0.3451
Echinococcus multilocularis glutathione s transferase mu 0.0025 0.0074 0.0171
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0067 0.0299 0.8598
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.031 0.894
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0113 0.0936
Trypanosoma brucei unspecified product 0.0039 0.0149 0.2658
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Leishmania major DNA damage repair protein, putative 0.0018 0.0032 0.0312
Loa Loa (eye worm) hypothetical protein 0.0038 0.0142 0.0919
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.021 0.1739
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.003 0.0117
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.021 0.0862
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0067 0.0299 0.2479
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0234 0.1198 0.2845
Onchocerca volvulus 0.0024 0.0066 0.0543
Schistosoma mansoni nuclear receptor 0.0024 0.0066 0.027
Onchocerca volvulus 0.003 0.0098 0.0813
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0417 0.0986
Trichomonas vaginalis pc-MYB2, putative 0.0027 0.0085 0.2113
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0025 0.01
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0245 0.1012
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0068 0.0302 0.1082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trypanosoma brucei calcium-translocating P-type ATPase 0.007 0.0315 0.5997
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0069 0.031 0.894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.021 0.1739
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0577 0.4096
Echinococcus granulosus FTZ F1 alpha 0.0051 0.021 0.0862
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0076 0.0345 0.1238
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.021 0.1739
Leishmania major P-type ATPase, putative 0.007 0.0315 0.5997
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0017 0.0067
Trypanosoma cruzi ISWI complex protein 0.0015 0.0017 0.001
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0057 0.126
Trypanosoma cruzi protein farnesyltransferase, putative 0.0067 0.0299 0.5679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0035 0.0124 0.2157
Echinococcus multilocularis cpg binding protein 0.0036 0.0131 0.0305
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0067 0.0299 0.2067
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0017 0.0035
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0044 0.0173 0.0156
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0579 0.0787
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.007 0.0315 0.1299
Plasmodium falciparum thioredoxin reductase 0.0047 0.019 0.5277
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0579 0.0787
Brugia malayi glutathione reductase 0.0047 0.019 0.1576
Trypanosoma brucei P-type H+-ATPase, putative 0.004 0.0154 0.2766
Brugia malayi nuclear hormone receptor 0.0051 0.021 0.1739
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0417 0.1726
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0066 0.0264
Brugia malayi Thioredoxin reductase 0.0047 0.019 0.1576
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0069 0.031 0.128
Echinococcus granulosus bloom syndrome protein 0.0022 0.0057 0.0227
Onchocerca volvulus 0.0051 0.021 0.1748
Echinococcus multilocularis dnaJ subfamily B 0.0459 0.2411 0.5732
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0033 0.0113 0.1931
Schistosoma mansoni hypothetical protein 0.0169 0.0845 0.3503
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0069 0.031 0.5902
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0194 0.098 0.4062
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0158 0.4326
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0142 0.3854
Leishmania major calcium-translocating P-type ATPase 0.0069 0.031 0.5902
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Onchocerca volvulus 0.0184 0.0927 0.7741
Plasmodium falciparum phosphodiesterase delta, putative 0.0033 0.0113 0.2924
Onchocerca volvulus 0.0234 0.1198 1
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0025 0.0289
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0035 0.0123 0.3234
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0025 0.0237
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0016 0.0022 0.0095
Trypanosoma cruzi P-type H+-ATPase, putative 0.004 0.0154 0.2766
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0703
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0069 0.031 0.5902
Echinococcus granulosus copper transporting ATPase 1 0.0015 0.0017 0.0061
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0033 0.0113 0.0264
Echinococcus granulosus phospholipid transporting atpase ih 0.0016 0.0022 0.0081
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.8934
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0032 0.0305
Trypanosoma brucei calcium-transporting ATPase, putative 0.0045 0.0178 0.3231
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Echinococcus granulosus geminin 0.0169 0.0845 0.3499
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0245 0.2026
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1341 0.7163 1
Giardia lamblia Prenyltransferase 0.0067 0.0299 0.2067
Brugia malayi E1-E2 ATPase family protein 0.0047 0.0189 0.1569
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.0043 0.0171 0.113
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0076 0.0345 0.0817
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0029 0.0093 0.1527
Schistosoma mansoni cation-transporting ATPase 0.0015 0.0017 0.0067
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.007 0.0315 0.0745
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.021 0.0494
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0032 0.0305
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0417 0.1726
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0278 0.0997
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.021 0.0494
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0245 0.0319
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0035 0.0119
Trypanosoma brucei unspecified product 0.0057 0.0245 0.4578
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0304 0.8733
Echinococcus granulosus phospholipid transporting ATPase IA 0.0016 0.0022 0.0081
Loa Loa (eye worm) hypothetical protein 0.0115 0.0554 0.393
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0022 0.0087
Brugia malayi hypothetical protein 0.0027 0.0081 0.0672
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0237
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0025 0.0008
Brugia malayi chromobox protein homolog 3 0.0038 0.0142 0.118
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0245 0.6931
Leishmania major geranylgeranyltransferase, putative 0.0018 0.0035 0.0368
Schistosoma mansoni cpg binding protein 0.0032 0.0111 0.0456
Leishmania major cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0018 0.0035 0.0608
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0027 0.0058
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0236 0.1207 0.2868
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0142 0.1184
Trypanosoma brucei unspecified product 0.0039 0.0149 0.2658
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0072 0.11
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0033 0.0113 0.046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0036 0.0639
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0025 0.0081
Echinococcus multilocularis nervana 2 0.0194 0.098 0.2326
Echinococcus granulosus dnaJ subfamily B 0.0459 0.2411 1
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.021 0.0862
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.007 0.0315 0.0745
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0076 0.0345 0.0329
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0057 0.1214
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Echinococcus granulosus prostaglandin H2 D isomerase 0.0025 0.0074 0.0299
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0033 0.0113 0.046
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0466
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.019 0.0448
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0067 0.0299 0.1239
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0074 0.0335 0.0445
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0022 0.0196
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0577 0.4096
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.4963
Giardia lamblia Myb 1-like protein 0.0028 0.0086 0.0503
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.019 0.0962 0.6919
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0057 0.0802
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.021 0.0862
Trypanosoma cruzi protein farnesyltransferase, putative 0.0067 0.0299 0.5679
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0057 0.013
Echinococcus granulosus cpg binding protein 0.0036 0.0131 0.0533
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0032 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Leishmania major hypothetical protein, conserved 0.0033 0.0113 0.1931
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0022 0.0196
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.047
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0025 0.0072 0.1665
Loa Loa (eye worm) hypothetical protein 0.0234 0.1198 0.8641
Giardia lamblia hypothetical protein 0.0033 0.0113 0.0703
Echinococcus granulosus calcium transporting atpase 0.007 0.0315 0.1299
Plasmodium falciparum thioredoxin reductase 0.0016 0.0025 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0018 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0107 0.0514 0.364
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0022 0.0095
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Brugia malayi hypothetical protein 0.0027 0.0081 0.0672
Schistosoma mansoni cation-transporting atpase worm 0.0015 0.0017 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0114
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0032 0.0108
Loa Loa (eye worm) hypothetical protein 0.0268 0.1383 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0268 0.1383 0.3287
Loa Loa (eye worm) hypothetical protein 0.0069 0.031 0.2148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.021 0.1413
Echinococcus multilocularis cation transporting ATPase 13A3 0.0015 0.0017 0.0035
Leishmania major lanosterol synthase, putative 0.0056 0.0236 0.441
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0245 0.0228
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0268 0.1383 0.4984
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0032 0.0462
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0082 0.0379 0.1571
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0185 0.0932 0.3864
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0069 0.031 0.1112
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Brugia malayi hypothetical protein 0.0024 0.0066 0.0544
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0033 0.0113 0.0936
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0401
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0033 0.0113 0.0936
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0069 0.031 0.5902
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0245 0.4578
Plasmodium vivax geranylgeranyltransferase, putative 0.0018 0.0035 0.0558
Echinococcus granulosus zinc finger protein 0.0021 0.005 0.0198
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0016 0.0022 0.0035
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0299 0.8605
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus multilocularis geminin 0.0169 0.0845 0.2005
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0032 0.0305
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0032 0.0266
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0245 0.1006
Trichomonas vaginalis MYB72, putative 0.0027 0.0085 0.2113
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0032 0.0312
Onchocerca volvulus 0.0024 0.0066 0.0543
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0268 0.1383 0.3287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0025 0.0157
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Trichomonas vaginalis MYB, putative 0.0028 0.0086 0.2135
Plasmodium falciparum glutathione reductase 0.0016 0.0025 0.0237
Brugia malayi conserved hypotetical protein 0.0024 0.0066 0.0544
Giardia lamblia Hypothetical protein 0.0033 0.0113 0.0703
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1867 1 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0033 0.0113 0.046
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.021 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.021 0.1739
Echinococcus multilocularis nervana 2 0.0234 0.1198 0.2845
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0417 0.2926
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.021 0.1739
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0025 0.0289
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.0197
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0113 0.2962
Schistosoma mansoni coup transcription factor 0.0051 0.021 0.0868
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus multilocularis cation transporting ATPase 13A1 0.0015 0.0017 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.021 0.1413
Brugia malayi Bromodomain containing protein 0.0075 0.0342 0.2829
Leishmania major DNA polymerase eta, putative 0.0068 0.0302 0.5733
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0035 0.0124 0.2157
Schistosoma mansoni DNA helicase recq5 0.0022 0.0057 0.0233
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0245 0.4578
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0234 0.1198 0.4963
Echinococcus granulosus cation transporting ATPase 13A3 0.0015 0.0017 0.0061
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0065 0.0263
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0015 0.0017 0.0053
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0018 0.0087
Echinococcus granulosus cation transporting ATPase 13A1 0.0015 0.0017 0.0061
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0703
Echinococcus granulosus glutathione s transferase mu 0.0025 0.0074 0.0299
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Brugia malayi polk-prov protein 0.0018 0.0032 0.0268
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0025 0.0072 0.0288
Loa Loa (eye worm) glutathione reductase 0.0047 0.019 0.1269
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.021 0.0862
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0016 0.0022 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0149 0.2658
Loa Loa (eye worm) PDE1B protein 0.0033 0.0113 0.0703
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0025 0.0072 0.11
Echinococcus multilocularis dna polymerase eta 0.0107 0.0514 0.1218
Brugia malayi hypothetical protein 0.0012 0.0002 0.0018
Mycobacterium ulcerans hypothetical protein 0.0018 0.0032 0.0016
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0194 0.098 0.2326
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0066 0.0264
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0032 0.0309
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.021 0.0494
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0033 0.0113 0.1931
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Leishmania major DNA polymerase kappa, putative 0.0018 0.0032 0.0312
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0015 0.0017 0.0053
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Schistosoma mansoni type V p-type atpase isoform 0.0015 0.0017 0.0067
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0066 0.027
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0068 0.0278
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.031 0.894
Plasmodium vivax P-type ATPase4, putative 0.0076 0.0345 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1709
Loa Loa (eye worm) hypothetical protein 0.0186 0.0941 0.676
Trypanosoma cruzi DNA polymerase eta, putative 0.0107 0.0514 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0081 0.0188
Echinococcus granulosus dna polymerase eta 0.0107 0.0514 0.2126
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.031 0.894
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Echinococcus granulosus glutathione S transferase Mu 1 0.0025 0.0074 0.0299
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0041 0.0158 0.43
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.021 0.1739
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0111 0.0686
Trypanosoma brucei DNA polymerase eta, putative 0.0107 0.0514 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0268 0.1383 0.5734
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0236 0.1207 1
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Schistosoma mansoni hypothetical protein 0.0169 0.0845 0.3503
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus granulosus glutathione S transferase 0.0025 0.0074 0.0299
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0057 0.0292
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.019 0.5277
Trypanosoma cruzi P-type H+-ATPase, putative 0.0035 0.0124 0.2157
Trichomonas vaginalis C-MYB, putative 0.0027 0.0085 0.2113
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0033 0.0113 0.1931
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0017 0.0061
Schistosoma mansoni hypothetical protein 0.0035 0.0126 0.0521
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0016 0.0022 0.0179
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.8934
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0593
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0526 0.2774 0.2762
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.1176
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0066 0.027
Trypanosoma cruzi lanosterol synthase, putative 0.0074 0.0335 0.6387
Trichomonas vaginalis DNA polymerase eta, putative 0.0057 0.0245 0.6947
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.007 0.0315 0.1305
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0113 0.2962
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0069 0.031 0.0733
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.021 0.0868
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0066 0.0544
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.021 0.1748
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.021 0.0862
Trypanosoma cruzi P-type H+-ATPase, putative 0.004 0.0154 0.2766
Schistosoma mansoni chromobox protein 0.0068 0.0304 0.1257
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0066 0.027
Echinococcus multilocularis zinc finger protein 0.0021 0.005 0.0113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.003 0.0123
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0033 0.0113 0.1931
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0113 0.0936
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0032 0.0312
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0069 0.031 0.5902
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0032 0.0305
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0025 0.0008
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0245 0.0228
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0018 0.0035 0.0558
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.019 0.0962 0.399
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0134
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0018 0.0035 0.0558
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.007 0.0315 0.1305
Echinococcus multilocularis glutathione S transferase 0.0025 0.0074 0.0171
Toxoplasma gondii hypothetical protein 0.0025 0.0072 0.025
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0018 0.0035 0.0119
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.021 0.0868
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0025 0.0072 0.0288
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Onchocerca volvulus 0.0194 0.098 0.8179
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0057 0.013
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0032 0.0071
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0065 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0245 0.1666
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.019 0.0781
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0036 0.0639
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Schistosoma mansoni bromodomain containing protein 0.0064 0.028 0.1158
Echinococcus granulosus nervana 2 0.0194 0.098 0.4059
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0015 0.0017 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.021 0.1739
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0025 0.0157
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0165 0.0825 0.6832
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.2037
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0022 0.0095
Plasmodium falciparum glutathione reductase 0.0047 0.019 0.5277
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.1931
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0057 0.0802
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0033 0.0113 0.0264
Brugia malayi CXXC zinc finger family protein 0.0032 0.0111 0.0916
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0032 0.0266
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0066 0.0357
Trypanosoma cruzi DNA polymerase eta, putative 0.0068 0.0302 0.5733
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0401
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0001 0.0011
Brugia malayi Glutathione S-transferase 4 0.002 0.0043 0.0354
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0022 0.0087
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.2962
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0032 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0068 0.1589
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0057 0.0292
Echinococcus multilocularis calcium transporting atpase 0.007 0.0315 0.0745
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0041 0.0158 0.131
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0126 0.0295
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0032 0.0131
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Leishmania major P-type H -ATPase, putative 0.004 0.0154 0.2766
Trypanosoma brucei lanosterol synthase 0.0074 0.0335 0.6387
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.021 0.0868
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0032 0.0124
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0033 0.0113 0.0264
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0032 0.0312
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.019
Mycobacterium tuberculosis Probable reductase 0.0107 0.0515 0.0697
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Schistosoma mansoni chromobox protein 0.0068 0.0304 0.1257
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0032 0.0312
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.021 0.1739
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0049 0.0652
Trypanosoma brucei calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0149 0.2658
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.021 0.0862
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0028 0.0086 0.2135
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0234 0.1198 0.4966
Toxoplasma gondii thioredoxin reductase 0.0047 0.019 0.0679
Leishmania major trypanothione reductase 0.0047 0.019 0.3486
Trichomonas vaginalis cation-transporting ATPase, putative 0.0015 0.0017 0.0053
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0236 0.1207 0.5003
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0044 0.0173 0.0218
Echinococcus granulosus chromobox protein 1 0.0068 0.0304 0.1251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0066 0.0544
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0018 0.0035 0.0143
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0057 0.1214
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0032 0.013
Trypanosoma cruzi lanosterol synthase, putative 0.0074 0.0335 0.6387
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0066 0.0151
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0064 0.028 0.1926
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.2037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.021 0.1739
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0194 0.098 0.4062
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0072 0.11
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0057 0.047
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0057 0.126
Schistosoma mansoni zinc finger protein 0.0024 0.0066 0.027
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0057 0.0227
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0066 0.0151
Brugia malayi Bromodomain containing protein 0.0037 0.0138 0.1147
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0033 0.0113 0.1931
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0016 0.0022 0.0095
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0057 0.1214
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0305 0.1264
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.0069 0.0309 0.2138
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0025 0.0237
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0065 0.0151
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.019 0.0243
Schistosoma mansoni nuclear receptor 0.0024 0.0066 0.027
Loa Loa (eye worm) hypothetical protein 0.0234 0.1198 0.8641
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0066 0.0357
Giardia lamblia Rab geranylgeranyltransferase 0.0025 0.0072 0.04
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0149 0.2658
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0032 0.0305
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0033 0.0113 0.1931
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0032 0.0071
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0018 0.0035 0.0608
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0018 0.0035 0.0558
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0035 0.0124 0.0785
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0052 0.1066
Trypanosoma cruzi ISWI complex protein 0.0015 0.0017 0.001
Plasmodium vivax glutathione S-transferase, putative 0.0025 0.0074 0.1745
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0015 0.0017 0.014
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0032 0.0312
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.0785
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.021 0.1413

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1 uM Inhibition of farnesyl transferase (FTase) of rat brain ChEMBL. No reference
IC50 (binding) = 1 uM Inhibition of farnesyl transferase (FTase) of rat brain ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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