Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0028 | 0.4393 | 0.5 | |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4678 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0531 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4678 | 0.4619 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4678 | 0.4619 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2266 | 0.4035 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.2266 | 0.4035 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.8476 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2266 | 0.4035 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.5602 | 0.6196 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.5602 | 0.6186 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.8867 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0754 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.8476 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.2266 | 0.1782 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2266 | 0.2181 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.8476 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2266 | 0.2181 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2266 | 0.2181 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5602 | 0.5553 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0754 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4393 | 0.4331 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.2266 | 0.4035 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2266 | 0.1761 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.2266 | 0.1761 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.8476 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2266 | 0.2181 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4678 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.2266 | 0.1782 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4393 | 0.4583 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4393 | 0.4597 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2266 | 0.4035 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2266 | 0.4035 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.