Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.003 | 0.4263 | 0.5 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.7016 | 0.7016 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.4263 | 0.4263 |
Onchocerca volvulus | 0.003 | 0.4263 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.4113 | 0.4113 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.7016 | 0.4799 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.4263 | 0.4263 |
Echinococcus multilocularis | musashi | 0.003 | 0.4263 | 0.4263 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.4263 | 0.4263 |
Brugia malayi | intermediate filament protein | 0.003 | 0.4263 | 0.4001 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.4263 | 0.4001 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.4263 | 0.4263 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.4263 | 0.4263 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.7016 | 0.7016 |
Echinococcus granulosus | lamin | 0.003 | 0.4263 | 0.4263 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.7016 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.7016 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0438 | 0.0438 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.7016 | 0.4799 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.4263 | 0.4263 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.7016 | 0.5 |
Brugia malayi | hypothetical protein | 0.0039 | 0.7016 | 0.688 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.7016 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.003 | 0.4263 | 0.4263 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.