Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha-glucosidase | 0.028 | 0.3251 | 0.3238 |
Mycobacterium ulcerans | pyruvate kinase | 0.0272 | 0.3151 | 0.3062 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.014 | 0.1449 | 0.4567 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0053 | 0.0035 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0053 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.2093 | 0.2093 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0283 | 0.0283 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.1951 | 0.1936 |
Brugia malayi | pyruvate kinase | 0.0057 | 0.0391 | 0.0391 |
Schistosoma mansoni | glutaminase | 0.0805 | 1 | 1 |
Schistosoma mansoni | pyruvate kinase | 0.0272 | 0.3151 | 0.3138 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0088 | 0.0785 | 0.0785 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0325 | 0.3832 | 0.3832 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0241 | 0.2751 | 0.2751 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0575 | 0.0575 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0072 | 0.0582 | 0.0582 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0575 | 0.1825 |
Echinococcus multilocularis | pyruvate kinase | 0.0272 | 0.3151 | 0.3763 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0129 | 0.041 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0575 | 0.0452 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0303 | 0.3541 | 0.3541 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0294 | 0.0877 |
Echinococcus multilocularis | pyruvate kinase | 0.014 | 0.1449 | 0.1718 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0129 | 0.0111 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0299 | 0.3498 | 0.418 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0072 | 0.0582 | 0.0582 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0516 | 0.0498 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0129 | 0.5 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.014 | 0.1449 | 0.4567 |
Entamoeba histolytica | pyruvate kinase, putative | 0.019 | 0.2093 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0575 | 0.0908 |
Loa Loa (eye worm) | TAR-binding protein | 0.0566 | 0.6928 | 0.6928 |
Echinococcus granulosus | tumor protein p63 | 0.0676 | 0.8344 | 1 |
Plasmodium vivax | pyruvate kinase, putative | 0.0272 | 0.3151 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0053 | 0.0035 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0072 | 0.0582 | 0.0582 |
Giardia lamblia | Pyruvate kinase | 0.0272 | 0.3151 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0575 | 0.1825 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0403 | 0.0403 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0072 | 0.0582 | 0.0582 |
Echinococcus multilocularis | pyruvate kinase | 0.014 | 0.1449 | 0.1718 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0575 | 0.1776 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0566 | 0.6928 | 0.6928 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0267 | 0.0249 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0575 | 0.0575 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.1951 | 0.1936 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0575 | 0.0452 |
Brugia malayi | Pre-SET motif family protein | 0.0058 | 0.0403 | 0.0403 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0458 | 0.5535 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0019 | 0.006 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0575 | 0.0452 |
Plasmodium vivax | SET domain protein, putative | 0.0058 | 0.0403 | 0.1225 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0053 | 0.0041 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.0914 | 0.0914 |
Schistosoma mansoni | pyruvate kinase | 0.0272 | 0.3151 | 0.3138 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.005 | 0.0294 | 0.0877 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0272 | 0.3151 | 0.3151 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0575 | 0.0908 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0129 | 0.0111 |
Echinococcus multilocularis | pyruvate kinase | 0.0215 | 0.2415 | 0.2878 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.3151 | 0.3151 |
Schistosoma mansoni | microtubule-associated protein tau | 0.067 | 0.8267 | 0.8264 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0072 | 0.0582 | 0.2779 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0058 | 0.0403 | 0.0384 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0272 | 0.3151 | 0.5639 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0575 | 0.0668 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0406 | 0.4868 | 0.4868 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0067 | 0.0067 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0072 | 0.0582 | 0.0676 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0294 | 0.0932 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0053 | 0.0041 |
Echinococcus multilocularis | snurportin 1 | 0.0303 | 0.3541 | 0.4231 |
Onchocerca volvulus | 0.0072 | 0.0575 | 0.1029 | |
Onchocerca volvulus | 0.0099 | 0.0927 | 0.1658 | |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0072 | 0.0582 | 0.0676 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0129 | 0.041 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.1099 | 0.1082 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0272 | 0.3151 | 0.5639 |
Leishmania major | pyruvate kinase | 0.0272 | 0.3151 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0575 | 0.0575 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0072 | 0.0582 | 0.2779 |
Brugia malayi | RNA binding protein | 0.0566 | 0.6928 | 0.6928 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0575 | 0.0575 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0325 | 0.3832 | 0.4581 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0088 | 0.0785 | 0.2446 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0112 | 0.1099 | 0.1082 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0267 | 0.0267 |
Brugia malayi | pyruvate kinase, muscle isozyme | 0.0057 | 0.0391 | 0.0391 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0575 | 0.0575 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0072 | 0.0582 | 0.0582 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0112 | 0.1099 | 0.1298 |
Trypanosoma brucei | glucosidase, putative | 0.0072 | 0.0582 | 0.1846 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0129 | 0.0618 |
Brugia malayi | TAR-binding protein | 0.0566 | 0.6928 | 0.6928 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0129 | 0.041 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0058 | 0.0403 | 0.0384 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.0914 | 0.0914 |
Mycobacterium ulcerans | glutaminase | 0.0805 | 1 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0129 | 0.0133 |
Brugia malayi | Pre-SET motif family protein | 0.0406 | 0.4868 | 0.4868 |
Schistosoma mansoni | tar DNA-binding protein | 0.0566 | 0.6928 | 0.6922 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0575 | 0.0668 |
Loa Loa (eye worm) | pyruvate kinase | 0.0272 | 0.3151 | 0.3151 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0575 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0294 | 0.0294 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0575 | 0.0908 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0566 | 0.6928 | 0.6928 |
Echinococcus granulosus | pyruvate kinase | 0.0272 | 0.3151 | 0.3763 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0516 | 0.0516 |
Echinococcus multilocularis | tumor protein p63 | 0.0676 | 0.8344 | 1 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0272 | 0.3151 | 0.3151 |
Brugia malayi | hypothetical protein | 0.005 | 0.0294 | 0.0294 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0575 | 0.0575 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0575 | 0.0575 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0575 | 0.0575 |
Schistosoma mansoni | tar DNA-binding protein | 0.0566 | 0.6928 | 0.6922 |
Echinococcus granulosus | pyruvate kinase | 0.014 | 0.1449 | 0.1718 |
Schistosoma mansoni | pyruvate kinase | 0.014 | 0.1449 | 0.1433 |
Brugia malayi | hypothetical protein | 0.0112 | 0.1099 | 0.1099 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0575 | 0.1825 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0575 | 0.0908 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0053 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0019 | 0.0019 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0234 | 0.2658 | 0.317 |
Leishmania major | hypothetical protein, conserved | 0.005 | 0.0294 | 0.0932 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0112 | 0.1099 | 0.1298 |
Onchocerca volvulus | 0.0048 | 0.0267 | 0.0478 | |
Schistosoma mansoni | hypothetical protein | 0.0303 | 0.3541 | 0.3529 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0325 | 0.3832 | 0.4581 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.0082 | 0.0713 | 0.0713 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0072 | 0.0582 | 0.0582 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0088 | 0.0785 | 0.2446 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0325 | 0.3832 | 0.3832 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0234 | 0.2658 | 0.317 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0053 | 0.0041 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0272 | 0.3151 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.2658 | 0.2658 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0081 | 0.0691 | 0.2145 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0072 | 0.0582 | 0.0582 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0072 | 0.0582 | 0.0582 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0575 | 0.0452 |
Schistosoma mansoni | alpha glucosidase | 0.0072 | 0.0582 | 0.0564 |
Loa Loa (eye worm) | glutaminase | 0.0805 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0582 | 0.1846 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0575 | 0.0575 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0072 | 0.0582 | 0.0582 |
Echinococcus multilocularis | pyruvate kinase | 0.0272 | 0.3151 | 0.3763 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0575 | 0.1825 |
Plasmodium falciparum | pyruvate kinase 2 | 0.014 | 0.1449 | 0.4567 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0283 | 0.0318 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0129 | 0.0129 |
Leishmania major | pyruvate kinase | 0.0272 | 0.3151 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.028 | 0.3251 | 0.3238 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0294 | 0.0932 |
Echinococcus multilocularis | pyruvate kinase | 0.014 | 0.1449 | 0.1718 |
Brugia malayi | MH2 domain containing protein | 0.0241 | 0.2751 | 0.2751 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.067 | 0.8267 | 0.9908 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0272 | 0.3151 | 0.3151 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0019 | 0.006 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0053 | 0.0053 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0058 | 0.0403 | 0.0461 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0575 | 0.0908 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0575 | 0.0908 |
Giardia lamblia | Pyruvate kinase | 0.014 | 0.1449 | 0.3083 |
Echinococcus granulosus | microtubule associated protein 2 | 0.067 | 0.8267 | 0.9908 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0575 | 0.0575 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0575 | 0.0575 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0575 | 0.0557 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0.0294 | 0.0877 |
Echinococcus granulosus | pyruvate kinase | 0.014 | 0.1449 | 0.1718 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0575 | 0.0908 |
Onchocerca volvulus | 0.0058 | 0.0403 | 0.072 | |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1099 | 0.525 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0088 | 0.0785 | 0.092 |
Onchocerca volvulus | 0.0188 | 0.2071 | 0.3706 | |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0129 | 0.0129 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0099 | 0.0927 | 0.0909 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0241 | 0.2751 | 0.2751 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0081 | 0.0691 | 0.33 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0272 | 0.3151 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0072 | 0.0582 | 0.1846 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0272 | 0.3151 | 0.3151 |
Echinococcus granulosus | geminin | 0.0179 | 0.1951 | 0.2321 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0058 | 0.0403 | 0.0461 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0294 | 0.0877 |
Loa Loa (eye worm) | pyruvate kinase | 0.0272 | 0.3151 | 0.3151 |
Trichomonas vaginalis | glutaminase, putative | 0.0805 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0072 | 0.0582 | 0.0582 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0058 | 0.0403 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0575 | 0.0575 |
Chlamydia trachomatis | pyruvate kinase | 0.0272 | 0.3151 | 0.5 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0272 | 0.3151 | 1 |
Brugia malayi | hypothetical protein | 0.0234 | 0.2658 | 0.2658 |
Schistosoma mansoni | tar DNA-binding protein | 0.0566 | 0.6928 | 0.6922 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0267 | 0.0249 |
Trichomonas vaginalis | set domain proteins, putative | 0.0462 | 0.5589 | 0.5589 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0283 | 0.0265 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0058 | 0.0403 | 0.1225 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0575 | 0.0908 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0129 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0053 | 0.0053 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0283 | 0.0318 |
Echinococcus granulosus | tar DNA binding protein | 0.0566 | 0.6928 | 0.8299 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0575 | 0.0575 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1099 | 0.525 |
Schistosoma mansoni | tar DNA-binding protein | 0.0566 | 0.6928 | 0.6922 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0088 | 0.0785 | 0.2446 |
Plasmodium falciparum | pyruvate kinase | 0.0272 | 0.3151 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0299 | 0.3498 | 0.3498 |
Echinococcus granulosus | pyruvate kinase | 0.014 | 0.1449 | 0.1718 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0283 | 0.0318 |
Loa Loa (eye worm) | pyruvate kinase | 0.0272 | 0.3151 | 0.3151 |
Echinococcus multilocularis | geminin | 0.0179 | 0.1951 | 0.2321 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.0914 | 0.0914 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0575 | 0.0575 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0575 | 0.0575 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0283 | 0.0265 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0272 | 0.3151 | 0.5631 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0058 | 0.0403 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0575 | 0.0575 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0575 | 0.0575 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0129 | 0.0353 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0575 | 0.0908 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0575 | 0.1776 |
Loa Loa (eye worm) | acetyltransferase | 0.0299 | 0.3498 | 0.3498 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.005 | 0.0294 | 0.0932 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0053 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0927 | 0.0927 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0914 | 0.0914 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0272 | 0.3151 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0283 | 0.0283 |
Echinococcus granulosus | snurportin 1 | 0.0303 | 0.3541 | 0.4231 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0283 | 0.0318 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0088 | 0.0785 | 0.0785 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0283 | 0.0265 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1099 | 0.525 |
Onchocerca volvulus | 0.0462 | 0.5589 | 1 | |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0575 | 0.1613 |
Loa Loa (eye worm) | pyruvate kinase | 0.0057 | 0.0391 | 0.0391 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0272 | 0.3151 | 1 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.019 | 0.2093 | 0.2093 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0129 | 0.0129 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0575 | 0.0908 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0053 | 0.0035 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0053 | 0.0041 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0582 | 0.1846 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0129 | 0.041 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0325 | 0.3832 | 0.4581 |
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0575 | 0.1613 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0575 | 0.0575 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0375 | 0.0428 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0058 | 0.0403 | 0.0384 |
Brugia malayi | glutaminase DH11.1 | 0.0805 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0566 | 0.6928 | 0.6928 |
Onchocerca volvulus | 0.0072 | 0.0575 | 0.1029 | |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0291 | 0.3391 | 0.405 |
Schistosoma mansoni | tar DNA-binding protein | 0.0566 | 0.6928 | 0.6922 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0072 | 0.0582 | 0.1797 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0072 | 0.0582 | 0.0582 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.069 | 0.069 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0272 | 0.3151 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0053 | 0.0053 |
Echinococcus multilocularis | tar DNA binding protein | 0.0566 | 0.6928 | 0.8299 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0575 | 0.0452 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0299 | 0.3498 | 0.3486 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0272 | 0.3151 | 0.5639 |
Onchocerca volvulus | 0.0072 | 0.0575 | 0.1029 | |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0129 | 0.0129 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1099 | 0.525 |
Echinococcus granulosus | pyruvate kinase | 0.0272 | 0.3151 | 0.3763 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.