Detailed information for compound 758798

Basic information

Technical information
  • TDR Targets ID: 758798
  • Name: N-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-4-meth oxybenzamide
  • MW: 343.379 | Formula: C21H17N3O2
  • H donors: 1 H acceptors: 2 LogP: 4.23 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C(=O)Nc1cccc(c1)c1nc2n(c1)cccc2
  • InChi: 1S/C21H17N3O2/c1-26-18-10-8-15(9-11-18)21(25)22-17-6-4-5-16(13-17)19-14-24-12-3-2-7-20(24)23-19/h2-14H,1H3,(H,22,25)
  • InChiKey: CNWXJJQLXVFGJS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-4-methoxy-benzamide
  • N-[3-(2-imidazo[1,2-a]pyridinyl)phenyl]-4-methoxybenzamide
  • Oprea1_845001
  • T5240715
  • ZINC00457211

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) pyruvate kinase 0.0044 0.0232 0.0497
Schistosoma mansoni hypothetical protein 0.0098 0.0783 0.2127
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0149 0.0486
Echinococcus multilocularis smad 0.0033 0.012 0.012
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0201 0.088
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.012 0.012
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0063 0.0427 0.0912
Brugia malayi MH2 domain containing protein 0.0033 0.012 0.0257
Echinococcus multilocularis tumor protein p63 0.1003 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0149 0.0574
Brugia malayi MH2 domain containing protein 0.0033 0.012 0.0257
Schistosoma mansoni tar DNA-binding protein 0.0382 0.3679 1
Loa Loa (eye worm) glutaminase 2 0.0264 0.248 0.53
Brugia malayi pyruvate kinase, muscle isozyme 0.0044 0.0232 0.0497
Loa Loa (eye worm) hypothetical protein 0.0051 0.0304 0.0649
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.0668 0.0668
Onchocerca volvulus 0.0036 0.0149 0.0786
Echinococcus granulosus tar DNA binding protein 0.0382 0.3679 0.3679
Schistosoma mansoni smad1 5 8 and 0.0033 0.012 0.0326
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0319
Brugia malayi hypothetical protein 0.0025 0.0036 0.0078
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.0668 0.3387
Brugia malayi hypothetical protein 0.0037 0.0161 0.0343
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0041 0.0201 0.088
Echinococcus multilocularis pyruvate kinase 0.0164 0.1457 0.1457
Echinococcus multilocularis pyruvate kinase 0.0208 0.1902 0.1902
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0149 0.0605
Schistosoma mansoni glutaminase 0.0264 0.248 0.6741
Onchocerca volvulus 0.0036 0.0149 0.0786
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0065
Schistosoma mansoni inositol monophosphatase 0.0037 0.016 0.0434
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0595 0.4583
Brugia malayi Pyruvate kinase, muscle isozyme 0.0208 0.1902 0.4066
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.016 0.066
Brugia malayi beta-lactamase 0.0036 0.0149 0.0319
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.016 0.016
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.016 0.0689
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.016 0.0043
Echinococcus granulosus pyruvate kinase 0.0107 0.0873 0.0873
Loa Loa (eye worm) transcription factor SMAD2 0.048 0.4679 1
Brugia malayi pyruvate kinase 0.0044 0.0232 0.0497
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.016 0.016
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.016 0.0043
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.1537 0.1537
Brugia malayi Inositol-1 0.0037 0.016 0.0341
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0319
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.0668 0.2227
Schistosoma mansoni smad1 5 8 and 0.0033 0.012 0.0326
Echinococcus granulosus pyruvate kinase 0.0208 0.1902 0.1902
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.2104 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.028 0.0761
Schistosoma mansoni transcription factor LCR-F1 0.0145 0.1262 0.343
Mycobacterium ulcerans pyruvate kinase 0.0208 0.1902 0.7642
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0145 0.1262 0.1262
Entamoeba histolytica hypothetical protein 0.0145 0.1262 0.9999
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.028 0.028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.028 0.0761
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.028 0.0761
Loa Loa (eye worm) glutaminase 0.0264 0.248 0.53
Echinococcus multilocularis pyruvate kinase 0.0107 0.0873 0.0873
Echinococcus granulosus pyruvate kinase 0.0107 0.0873 0.0873
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.0668 0.3387
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0175 0.011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0175 0.1174
Brugia malayi AMP-binding enzyme family protein 0.0024 0.003 0.0065
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0294 0.2785 0.7571
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0175 0.011
Loa Loa (eye worm) hypothetical protein 0.0035 0.014 0.0299
Brugia malayi glutaminase DH11.1 0.0264 0.248 0.53
Schistosoma mansoni tar DNA-binding protein 0.0382 0.3679 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0175 0.1174
Schistosoma mansoni alpha-glucosidase 0.0148 0.1293 0.3515
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0149 0.0605
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0149 0.0574
Brugia malayi RNA binding protein 0.0382 0.3679 0.7862
Onchocerca volvulus Pyruvate kinase homolog 0.0208 0.1902 1
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0149 0.0574
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0319
Echinococcus granulosus geminin 0.0164 0.1456 0.1456
Echinococcus granulosus survival motor neuron protein 1 0.0479 0.4669 0.4669
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0201 0.0429
Brugia malayi beta-lactamase family protein 0.0036 0.0149 0.0319
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0201 0.0429
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.012 0.0257
Trypanosoma cruzi pyruvate kinase 2, putative 0.0208 0.1902 1
Loa Loa (eye worm) pyruvate kinase 0.0208 0.1902 0.4066
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0319
Echinococcus granulosus pyruvate kinase 0.0107 0.0873 0.0873
Toxoplasma gondii pyruvate kinase PyKII 0.0107 0.0873 0.4481
Entamoeba histolytica hypothetical protein 0.0145 0.1262 0.9999
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0175 0.011
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0078
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.016 0.1048
Schistosoma mansoni cellular tumor antigen P53 0.0147 0.1282 0.3484
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0175 0.011
Brugia malayi AMP-binding enzyme family protein 0.0024 0.003 0.0065
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.016 0.0527
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.016 0.5
Onchocerca volvulus Pyruvate kinase homolog 0.0208 0.1902 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.028 0.028
Trichomonas vaginalis glutaminase, putative 0.0264 0.248 1
Echinococcus granulosus pyruvate kinase 0.0208 0.1902 0.1902
Onchocerca volvulus 0.0024 0.003 0.016
Brugia malayi AMP-binding enzyme family protein 0.0024 0.003 0.0065
Loa Loa (eye worm) hypothetical protein 0.0145 0.1262 0.2697
Loa Loa (eye worm) pyruvate kinase 0.0208 0.1902 0.4066
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.1537 0.3284
Schistosoma mansoni pyruvate kinase 0.0107 0.0873 0.2372
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.012 0.0326
Entamoeba histolytica hypothetical protein 0.0145 0.1262 0.9999
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0319
Loa Loa (eye worm) MH2 domain-containing protein 0.048 0.4679 1
Brugia malayi MH1 domain containing protein 0.0033 0.012 0.0257
Brugia malayi hypothetical protein 0.0145 0.1262 0.2697
Schistosoma mansoni alpha glucosidase 0.0038 0.0175 0.0476
Loa Loa (eye worm) beta-lactamase 0.0036 0.0149 0.0319
Trichomonas vaginalis pyruvate kinase, putative 0.0208 0.1902 0.7522
Schistosoma mansoni hypothetical protein 0.0164 0.1456 0.3958
Brugia malayi TAR-binding protein 0.0382 0.3679 0.7862
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0149 0.0319
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.016 0.066
Echinococcus granulosus histone acetyltransferase KAT2B 0.0286 0.2701 0.2701
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0149 0.0406
Onchocerca volvulus Pyruvate kinase homolog 0.0208 0.1902 1
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0149 0.0574
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0065
Giardia lamblia Pyruvate kinase 0.0208 0.1902 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0304 0.0649
Schistosoma mansoni Smad4 0.0033 0.012 0.0326
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0175 0.011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0201 0.0429
Echinococcus multilocularis pyruvate kinase 0.0107 0.0873 0.0873
Loa Loa (eye worm) TAR-binding protein 0.0382 0.3679 0.7862
Schistosoma mansoni inositol monophosphatase 0.0037 0.016 0.0434
Brugia malayi beta-lactamase family protein 0.0036 0.0149 0.0319
Loa Loa (eye worm) inositol-1 0.0037 0.016 0.0341
Entamoeba histolytica pyruvate kinase, putative 0.0145 0.1262 1
Echinococcus multilocularis pyruvate kinase 0.0208 0.1902 0.1902
Schistosoma mansoni tar DNA-binding protein 0.0382 0.3679 1
Loa Loa (eye worm) hypothetical protein 0.0479 0.4669 0.9979
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0149 0.0574
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0175 0.0743
Plasmodium vivax pyruvate kinase, putative 0.0208 0.1902 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0175 0.0175
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0304 0.0649
Trichomonas vaginalis pyruvate kinase, putative 0.0208 0.1902 0.7522
Schistosoma mansoni smad1 5 8 and 0.0033 0.012 0.0326
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.0668 0.2227
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.028 0.028
Trypanosoma brucei pyruvate kinase 1 0.0208 0.1902 1
Echinococcus granulosus smad 0.0033 0.012 0.012
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0175 0.0374
Loa Loa (eye worm) hypothetical protein 0.0208 0.1902 0.4066
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.016 0.0043
Schistosoma mansoni hypothetical protein 0.0035 0.014 0.0381
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.012 0.012
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0595 0.2994
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0175 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0149 0.0605
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0201 0.0429
Brugia malayi MH1 domain containing protein 0.0033 0.012 0.0257
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0201 0.0201
Loa Loa (eye worm) pyruvate kinase 0.0208 0.1902 0.4066
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0149 0.0149
Echinococcus multilocularis geminin 0.0164 0.1456 0.1456
Loa Loa (eye worm) pyruvate kinase-PB 0.0145 0.1262 0.2697
Plasmodium vivax pyruvate kinase 2, putative 0.0107 0.0873 0.4481
Echinococcus granulosus Smad4 0.0033 0.012 0.012
Trypanosoma brucei pyruvate kinase 1, putative 0.0208 0.1902 1
Brugia malayi RNA recognition motif domain containing protein 0.0382 0.3679 0.7862
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.016 0.066
Onchocerca volvulus 0.0098 0.0783 0.4114
Trypanosoma cruzi pyruvate kinase 2, putative 0.0208 0.1902 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.1537 0.3284
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0175 0.0772
Brugia malayi Smad1 0.0033 0.012 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0149 0.0605
Schistosoma mansoni tar DNA-binding protein 0.0382 0.3679 1
Echinococcus multilocularis survival motor neuron protein 1 0.0479 0.4669 0.4669
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0149 0.0574
Echinococcus multilocularis tar DNA binding protein 0.0382 0.3679 0.3679
Trypanosoma brucei glucosidase, putative 0.0038 0.0175 0.0743
Toxoplasma gondii pyruvate kinase PyK1 0.0208 0.1902 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0319
Plasmodium falciparum pyruvate kinase 0.0208 0.1902 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.028 0.0598
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0175 0.0374
Leishmania major hypothetical protein, conserved 0.0025 0.0036 0.0032
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.016 0.066
Mycobacterium ulcerans beta-lactamase 0.0036 0.0149 0.0486
Mycobacterium ulcerans hypothetical protein 0.0036 0.0149 0.0486
Mycobacterium ulcerans glutaminase 0.0264 0.248 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0149 0.0574
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0294 0.2785 0.2785
Schistosoma mansoni smad 0.0033 0.012 0.0326
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0783 0.1673
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0175 0.011
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0149 0.0635
Mycobacterium leprae Probable pyruvate kinase PykA 0.0208 0.1902 1
Entamoeba histolytica hypothetical protein 0.0145 0.1262 0.9999
Loa Loa (eye worm) Smad1 0.0033 0.012 0.0257
Onchocerca volvulus 0.0147 0.1282 0.6737
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.028 0.0598
Leishmania major pyruvate kinase 0.0208 0.1902 1
Brugia malayi hypothetical protein 0.0037 0.0161 0.0343
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0208 0.1902 0.9027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0149 0.0406
Onchocerca volvulus 0.0099 0.0799 0.42
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.028 0.028
Plasmodium falciparum pyruvate kinase 2 0.0107 0.0873 0.4481
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0149 0.0319
Schistosoma mansoni hypothetical protein 0.0041 0.0201 0.0546
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.012 0.0434
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.0668 0.3387
Schistosoma mansoni hypothetical protein 0.0145 0.1262 0.343
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0175 0.0743
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0175 0.0743
Giardia lamblia Pyruvate kinase 0.0107 0.0873 0.2123
Brugia malayi hypothetical protein 0.0479 0.4669 0.9979
Mycobacterium tuberculosis Conserved protein 0.0036 0.0149 0.0574
Leishmania major hypothetical protein, conserved 0.0036 0.0149 0.0635
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0175 0.011
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0149 0.0486
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.1537 0.1537
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.014 0.0299
Schistosoma mansoni pyruvate kinase 0.0208 0.1902 0.5171
Echinococcus multilocularis pyruvate kinase 0.0107 0.0873 0.0873
Schistosoma mansoni alpha-glucosidase 0.0148 0.1293 0.3515
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.012 0.0257
Echinococcus multilocularis Smad4 0.0033 0.012 0.012
Loa Loa (eye worm) RNA binding protein 0.0382 0.3679 0.7862
Chlamydia trachomatis pyruvate kinase 0.0208 0.1902 0.5
Schistosoma mansoni survival motor neuron protein 0.0098 0.0783 0.2127
Loa Loa (eye worm) acetyltransferase 0.0294 0.2785 0.5952
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0304 0.0649
Mycobacterium tuberculosis Conserved protein 0.0036 0.0149 0.0574
Schistosoma mansoni tar DNA-binding protein 0.0382 0.3679 1
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0201 0.088
Schistosoma mansoni hypothetical protein 0.0164 0.1456 0.3958
Schistosoma mansoni pyruvate kinase 0.0208 0.1902 0.5171
Brugia malayi acetyltransferase, GNAT family protein 0.0294 0.2785 0.5952
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.012 0.012
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0065
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.012 0.0481
Mycobacterium leprae Probable lipase LipE 0.0036 0.0149 0.0635
Mycobacterium ulcerans lipase LipD 0.0036 0.0149 0.0486
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0149 0.0574
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0175 0.011
Brugia malayi Pyruvate kinase, M2 isozyme 0.0208 0.1902 0.4066
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.1537 0.1537
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0382 0.3679 0.7862
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0147 0.1282 0.2739
Toxoplasma gondii ABC1 family protein 0.0036 0.0149 0.0605
Leishmania major pyruvate kinase 0.0208 0.1902 1
Brugia malayi MH2 domain containing protein 0.048 0.4679 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0145 0.1262 0.1262
Onchocerca volvulus 0.0036 0.0149 0.0786

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.