Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0861 | 0.0861 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0861 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0861 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0861 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0861 | 0.5 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0861 | 0.0861 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0861 | 0.0861 |
Onchocerca volvulus | 0.0035 | 0.0861 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.2614 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0861 | 0.1381 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0861 | 0.1381 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0146 | 0.6234 | 1 |
Brugia malayi | hypothetical protein | 0.0071 | 0.2614 | 0.4192 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0861 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.6234 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.6234 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0017 | 0 | 0.5 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0861 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0861 | 0.5 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0861 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0861 | 0.0861 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0861 | 0.0861 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.2614 | 0.4192 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.2614 | 0.4192 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1513 | 0.2427 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0861 | 0.5 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0861 | 0.1381 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.6234 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.077 | 0.1235 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0861 | 0.0861 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0861 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0146 | 0.6234 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0861 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.2614 | 0.4192 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.6234 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1513 | 0.2427 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.2614 | 0.5 |
Onchocerca volvulus | 0.0035 | 0.0861 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0861 | 0.1381 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0861 | 0.0861 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0861 | 0.0861 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0861 | 0.1381 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.2614 | 0.4192 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.2614 | 0.5 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0861 | 0.1381 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0861 | 0.0861 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0861 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1513 | 0.2427 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0861 | 0.1381 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0861 | 0.1381 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1513 | 0.2427 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0861 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0861 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0861 | 0.1381 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.6234 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0861 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0861 | 0.1381 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0861 | 0.1381 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0861 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.6234 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.2614 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0861 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0861 | 0.1381 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0861 | 0.1381 |
Onchocerca volvulus | 0.0035 | 0.0861 | 0.5 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0861 | 0.1381 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.077 | 0.1235 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0861 | 0.1381 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0861 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.077 | 0.1235 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0861 | 0.5 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0861 | 0.0861 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.6234 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0861 | 0.1381 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.