Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0043 | 0.0277 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0152 | 0.1339 | 0.335 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.0159 | 0.043 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0226 | 0.0041 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0043 | 0.0277 | 0.0472 |
Onchocerca volvulus | 0.0043 | 0.0277 | 0.1237 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0148 | 0.1295 | 1 |
Onchocerca volvulus | 0.0038 | 0.0226 | 0.0821 | |
Toxoplasma gondii | propionate-CoA ligase | 0.0043 | 0.0277 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 0.0127 | 0.0283 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0387 | 0.1045 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0387 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0218 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Brugia malayi | AMP-binding enzyme family protein | 0.0148 | 0.1295 | 0.3495 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0043 | 0.0277 | 0.0292 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0277 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.011 | 0.0931 | 0.659 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0277 | 0.0292 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0022 | 0.0007 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0421 | 0.3967 | 0.3958 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0159 | 0.0144 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0148 | 0.1295 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0159 | 0.043 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0218 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0226 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0043 | 0.0277 | 0.0262 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0277 | 0.0292 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0043 | 0.0277 | 0.0747 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0043 | 0.0277 | 0.0472 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0043 | 0.0277 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0226 | 0.0041 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0022 | 0.0007 |
Brugia malayi | RNA binding protein | 0.0394 | 0.3705 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 0.0127 | 0.0283 |
Schistosoma mansoni | hypothetical protein | 0.039 | 0.3661 | 0.9226 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0015 | 0.0041 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0015 | 0.0041 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0127 | 0.0342 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0022 | 0.0007 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0043 | 0.0277 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0226 | 0.0611 |
Onchocerca volvulus | 0.0043 | 0.0277 | 0.1237 | |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | nuclear receptor RXR | 0.0017 | 0.0015 | 0.0041 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0148 | 0.1295 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0159 | 0.043 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0127 | 0.0283 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0043 | 0.0277 | 0.0472 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0148 | 0.1295 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0226 | 0.0041 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0159 | 0.0365 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0159 | 0.043 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0022 | 0.006 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0226 | 0.0535 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0022 | 0.0018 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0148 | 0.1295 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0043 | 0.0277 | 0.0262 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.3705 | 0.9337 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0127 | 0.0342 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0159 | 0.043 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0159 | 0.043 |
Loa Loa (eye worm) | TAR-binding protein | 0.0394 | 0.3705 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0104 | 0.0872 | 0.3242 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0148 | 0.1295 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0226 | 0.0611 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0226 | 0.0041 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0148 | 0.1295 | 0.534 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0277 | 0.0292 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.011 | 0.0931 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0186 | 0.1665 | 1 |
Onchocerca volvulus | 0.0043 | 0.0277 | 0.1237 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0159 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1295 | 0.3495 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.0159 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0931 | 0.2512 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.3705 | 0.9337 |
Echinococcus granulosus | tar DNA binding protein | 0.0394 | 0.3705 | 0.3695 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0022 | 0.0007 |
Plasmodium falciparum | acyl-CoA synthetase | 0.011 | 0.0931 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0277 | 0.0747 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0394 | 0.3705 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0043 | 0.0277 | 0.0747 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.0159 | 0.0144 |
Loa Loa (eye worm) | RNA binding protein | 0.0394 | 0.3705 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0421 | 0.3967 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0186 | 0.1665 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0277 | 0.0747 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0277 | 0.0747 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1295 | 0.3495 |
Brugia malayi | AMP-binding enzyme family protein | 0.0148 | 0.1295 | 0.3495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.3705 | 0.9337 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Brugia malayi | hypothetical protein | 0.0186 | 0.1665 | 0.4495 |
Entamoeba histolytica | hypothetical protein | 0.0186 | 0.1665 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0226 | 0.0041 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0043 | 0.0277 | 0.0717 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.0159 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0931 | 0.2512 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0043 | 0.0277 | 0.0292 |
Echinococcus granulosus | lamin | 0.0028 | 0.0127 | 0.0112 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0226 | 0.0041 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.0159 | 0.0365 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0159 | 0.043 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0022 | 0.0007 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0244 | 0.2235 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0148 | 0.1295 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0127 | 0.0342 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0043 | 0.0277 | 0.0292 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0127 | 0.0112 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0394 | 0.3705 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0159 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0226 | 0.0611 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0387 | 0.1045 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0127 | 0.0112 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0043 | 0.0277 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.039 | 0.3661 | 0.3652 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0043 | 0.0277 | 0.0747 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0104 | 0.0872 | 0.3242 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.0159 | 0.043 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0159 | 0.0365 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.0159 | 0.0365 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0127 | 0.0112 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.3705 | 0.9337 |
Echinococcus multilocularis | tar DNA binding protein | 0.0394 | 0.3705 | 0.3695 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0148 | 0.1295 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0159 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0226 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0226 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0127 | 0.0342 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0148 | 0.1295 | 0.7332 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0226 | 0.0611 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0186 | 0.1665 | 0.1653 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0159 | 0.043 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.0159 | 0.043 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.0159 | 0.0365 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0186 | 0.1665 | 0.4176 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0148 | 0.1295 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1295 | 0.3495 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0043 | 0.0277 | 0.0662 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0277 | 0.0747 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0043 | 0.0277 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.0159 | 0.0365 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.1063 | 0.287 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Brugia malayi | TAR-binding protein | 0.0394 | 0.3705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.0159 | 0.0144 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0017 | 0.0015 | 0.0041 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0186 | 0.1665 | 0.1653 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0043 | 0.0277 | 0.0292 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | AMP-binding enzyme family protein | 0.0148 | 0.1295 | 0.3495 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0159 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0022 | 0.0018 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.0159 | 0.0144 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0043 | 0.0277 | 0.0292 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.1063 | 0.287 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0043 | 0.0277 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0159 | 0.0144 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0043 | 0.0277 | 0.0472 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0043 | 0.0277 | 0.0472 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0159 | 0.043 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0159 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0931 | 0.2512 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.0159 | 0.0144 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.011 | 0.0931 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0043 | 0.0277 | 0.0747 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0148 | 0.1295 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0148 | 0.1295 | 0.534 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0226 | 0.0611 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.0159 | 0.0268 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0104 | 0.0872 | 0.3242 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0043 | 0.0277 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.1039 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.0159 | 0.043 |
Onchocerca volvulus | 0.0152 | 0.1339 | 1 | |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0043 | 0.0277 | 0.0292 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0043 | 0.0277 | 0.0472 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0148 | 0.1295 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0127 | 0.0342 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.0159 | 0.0365 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0043 | 0.0277 | 0.0472 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0159 | 0.0144 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0226 | 0.0535 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0159 | 0.043 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.0159 | 0.0268 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0159 | 0.043 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0226 | 0.0212 |
Onchocerca volvulus | 0.0043 | 0.0277 | 0.1237 | |
Onchocerca volvulus | 0.0038 | 0.0226 | 0.0821 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0277 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0226 | 0.0611 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0277 | 0.0472 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.0159 | 0.0144 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0226 | 0.0041 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0148 | 0.1295 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0122 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0159 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0931 | 0.2512 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.0159 | 0.0268 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0387 | 0.1045 |
Onchocerca volvulus | 0.0148 | 0.1295 | 0.9639 | |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.039 | 0.3661 | 0.3652 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0159 | 0.0144 |
Entamoeba histolytica | hypothetical protein | 0.0186 | 0.1665 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0159 | 0.043 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0226 | 0.0041 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0226 | 0.0212 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0043 | 0.0277 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0043 | 0.0277 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0159 | 0.043 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0226 | 0.0611 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.0159 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1339 | 0.3614 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.1063 | 0.287 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0226 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0022 | 0.006 |
Onchocerca volvulus | 0.0038 | 0.0226 | 0.0821 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0148 | 0.1295 | 0.7332 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0022 | 0.0007 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0148 | 0.1295 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0148 | 0.1295 | 0.7332 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0022 | 0.006 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0159 | 0.043 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0159 | 0.0144 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0226 | 0.0611 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.0159 | 0.0365 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.0159 | 0.043 |
Onchocerca volvulus | 0.0031 | 0.0159 | 0.0268 | |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0043 | 0.0277 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0022 | 0.0018 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0226 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0931 | 0.2512 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0277 | 0.0747 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.1665 | 0.4176 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0277 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0043 | 0.0277 | 0.0747 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.0159 | 0.0365 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0127 | 0.0112 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0226 | 0.0611 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0218 | 0.0589 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.0159 | 0.043 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0127 | 0.0112 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.011 | 0.0931 | 0.3533 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0022 | 0.006 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0159 | 0.0144 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0104 | 0.0872 | 0.3242 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0277 | 0.0747 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0277 | 0.0472 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.0159 | 0.0365 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0277 | 0.0292 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0015 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0022 | 0.0018 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.0159 | 0.0144 |
Schistosoma mansoni | thyroid hormone receptor | 0.0421 | 0.3967 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.3705 | 0.9337 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.