Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.4023 | 0.4023 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.4023 | 0.4023 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 1 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.4023 | 0.4023 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.4023 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 1 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.4023 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Onchocerca volvulus | 0.0021 | 0 | 0.5 | |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 1 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0065 | 1 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.4023 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.4023 | 0.4023 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.4023 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.4023 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.