Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.5039 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1077 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5039 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 1 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.3571 | 0.699 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0545 | 0.0545 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0914 | 0.5 |
Echinococcus multilocularis | geminin | 0.0176 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0545 | 0.0788 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0545 | 0.0545 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0545 | 0.0545 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.2959 | 0.5736 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.3279 | 0.6084 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.2529 | 0.2529 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0545 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.2959 | 0.2959 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1238 | 0.1542 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0911 | 0.0911 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.5039 | 1 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.1072 | 0.1868 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0545 | 0.0545 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0911 | 0.0911 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.2773 | 0.2773 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0545 | 0.0545 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0914 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2959 | 0.5371 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0545 | 0.0545 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0914 | 0.0914 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0914 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1368 | 0.1832 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0914 | 0.0914 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0914 | 0.0914 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0545 | 0.0788 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0914 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.5039 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0545 | 0.0545 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0914 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0545 | 0.0545 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0914 | 0.1544 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.2529 | 0.2529 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.