Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.5833 | 0.5833 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.5627 | 0.5627 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.8382 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.5833 | 0.5568 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.5833 | 0.5833 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.5833 | 0.5833 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | lamin | 0.0027 | 0.5833 | 0.5833 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.5833 | 0.5833 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 1 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 1 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 1 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 1 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 1 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 1 | 0.5 |
Onchocerca volvulus | 0.0027 | 0.5833 | 0.5 | |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 1 | 0.5 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.5833 | 0.5833 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.5833 | 0.5833 |
Echinococcus multilocularis | lamin | 0.0027 | 0.5833 | 0.5833 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.5833 | 0.5833 |
Onchocerca volvulus | 0.0027 | 0.5833 | 0.5 | |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.8382 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 1 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0599 | 0.0599 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 1 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.5833 | 0.5568 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.