Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2686 | 0.4014 |
Brugia malayi | Bromodomain containing protein | 0.0079 | 0.7263 | 0.7097 |
Schistosoma mansoni | bromodomain containing protein | 0.0067 | 0.5698 | 0.7722 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.5219 | 0.5094 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0101 | 1 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.1138 | 0.5 |
Echinococcus granulosus | peregrin | 0.0033 | 0.1455 | 0.1231 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.7378 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.2213 | 0.2999 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.1455 | 0.0937 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.5219 | 0.5094 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.2941 | 0.4395 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.1138 | 0.5 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.1138 | 0.0601 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1138 | 0.1543 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.3903 | 0.5833 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.1138 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.3903 | 0.5833 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.1138 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.1138 | 0.1701 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.237 | 0.3541 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.1138 | 0.5 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.2664 | 0.2472 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.1138 | 0.1543 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0255 | 0.0346 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.236 | 0.1897 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.6692 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.1958 | 0.1747 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.3903 | 0.3534 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1138 | 0.1701 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.3921 | 0.5859 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.2213 | 0.2009 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.2664 | 0.2472 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.1138 | 0.0906 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.1455 | 0.1231 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.2213 | 0.1741 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1796 | 0.2434 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.1796 | 0.1299 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0101 | 1 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.2044 | 0.1835 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.2213 | 0.3307 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.1138 | 0.0906 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.5286 | 0.7899 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.1138 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1796 | 0.2684 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.3903 | 0.3534 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.2044 | 0.1835 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.2213 | 0.2999 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.