Detailed information for compound 762161

Basic information

Technical information
  • TDR Targets ID: 762161
  • Name: 2-amino-4-(4-methylphenyl)-5-oxo-1-(2H-1,2,4- triazol-3-yl)-4,6,7,8-tetrahydroquinoline-3-c arbonitrile
  • MW: 346.386 | Formula: C19H18N6O
  • H donors: 2 H acceptors: 4 LogP: 1.78 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CC1=C(N)N(c2nc[nH]n2)C2=C(C1c1ccc(cc1)C)C(=O)CCC2
  • InChi: 1S/C19H18N6O/c1-11-5-7-12(8-6-11)16-13(9-20)18(21)25(19-22-10-23-24-19)14-3-2-4-15(26)17(14)16/h5-8,10,16H,2-4,21H2,1H3,(H,22,23,24)
  • InChiKey: BWQCFPZMLHHVEJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-amino-5-keto-4-(4-methylphenyl)-1-(2H-1,2,4-triazol-3-yl)-4,6,7,8-tetrahydroquinoline-3-carbonitrile
  • Oprea1_083479

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0062 0.0334 0.0465
Brugia malayi nuclear receptor NHR-88 0.0039 0.0164 0.0229
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Schistosoma mansoni jumonji/arid domain-containing protein 0.0103 0.0631 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0219 0.0577
Brugia malayi steroid hormone receptor 0.0083 0.0483 0.0672
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0943 0.2487
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Brugia malayi Ets-domain containing protein 0.0073 0.0411 0.0571
Brugia malayi Pre-SET motif family protein 0.0472 0.3319 0.4617
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Echinococcus multilocularis thyroid hormone receptor alpha 0.1114 0.7995 0.7995
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0164 0.0434
Echinococcus multilocularis tar DNA binding protein 0.0462 0.3247 0.3247
Brugia malayi Latrophilin receptor protein 2 0.0081 0.047 0.0654
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.004 0.0055
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0219 0.1339
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0164 0.0164
Schistosoma mansoni ferritin 0.0086 0.0505 0.0505
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0199 0.0199
Loa Loa (eye worm) MH2 domain-containing protein 0.0031 0.0103 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0107 0.0282
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0943 0.2487
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0219 0.1339
Trichomonas vaginalis CMGC family protein kinase 0.0222 0.15 0.3954
Loa Loa (eye worm) nuclear factor I 0.0038 0.0155 0.0216
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0219 0.0219
Onchocerca volvulus 0.0083 0.0483 0.1274
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0068 0.0372 0.0372
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0795 0.5668 0.5668
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.0943 0.1386
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Echinococcus multilocularis lysine specific demethylase 5A 0.0099 0.0604 0.0604
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0073 0.0073
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium ulcerans lipase LipD 0.0146 0.0943 0.1633
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Brugia malayi MH2 domain containing protein 0.0068 0.0378 0.0526
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.0943 0.1633
Brugia malayi hypothetical protein 0.0039 0.0164 0.0229
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.004 0.007
Mycobacterium ulcerans hypothetical protein 0.0146 0.0943 0.1633
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0164 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.0483 0.0672
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.004 0.0172
Loa Loa (eye worm) isocitrate dehydrogenase 0.0068 0.0372 0.0518
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.1575 0.1575
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0044 0.02 0.0279
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.0483 0.0672
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.0943 0.1633
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.0483 0.0672
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.0483 0.0672
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0164 0.0229
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0073 0.0073
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0352 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0107 0.0282
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0372 0.0657
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.004 0.0105
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.1575 0.1575
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0199 0.0276
Schistosoma mansoni nuclear receptor 0.0039 0.0164 0.0164
Leishmania major cathepsin L-like protease 0.0063 0.0337 0.2249
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.004 0.0105
Echinococcus multilocularis tumor protein p63 0.0348 0.2413 0.2413
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0022 0.004 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Loa Loa (eye worm) hypothetical protein 0.0044 0.0199 0.0276
Echinococcus granulosus neuropeptide receptor A26 0.0459 0.322 0.322
Trichomonas vaginalis esterase, putative 0.0146 0.0943 0.2487
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0022 0.004 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.047 0.047
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0483 0.0672
Mycobacterium tuberculosis Conserved protein 0.0146 0.0943 0.1386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0166
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0172
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0372 0.2481
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Loa Loa (eye worm) hypothetical protein 0.0062 0.0334 0.0464
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0943 0.6288
Brugia malayi Thioredoxin reductase 0.0151 0.0981 0.1365
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.004 0.004
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0022 0.004 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.004 0.0128
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0068 0.0378 0.0378
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0222 0.15 1
Onchocerca volvulus 0.0358 0.2489 0.6563
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi RNA recognition motif domain containing protein 0.0462 0.3247 0.4516
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni ferritin 0.0086 0.0505 0.0505
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0022 0.004 0.004
Brugia malayi SET domain containing protein 0.0017 0.0002 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Loa Loa (eye worm) hypothetical protein 0.0146 0.0943 0.1312
Brugia malayi RNA binding protein 0.0462 0.3247 0.4516
Giardia lamblia DUB-1 0.0022 0.004 0.0128
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0068 0.0372 0.0657
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.0483 0.0672
Trypanosoma brucei trypanothione reductase 0.0151 0.0981 0.6495
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.0483 0.0483
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.1031 0.7392 0.7392
Onchocerca volvulus 0.0051 0.0251 0.0661
Brugia malayi MH1 domain containing protein 0.0038 0.0155 0.0216
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0021 0.0037
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0222 0.15 0.2086
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0483 0.0672
Entamoeba histolytica hypothetical protein 0.0335 0.2319 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.0483 0.0483
Echinococcus multilocularis peptidase Clp (S14 family) 0.0521 0.3674 0.3674
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.004 0.0055
Brugia malayi jmjC domain containing protein 0.0027 0.0073 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Plasmodium vivax hypothetical protein, conserved 0.003 0.0098 0.0174
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0189 0.1255 0.1856
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0161 0.1056 0.1056
Toxoplasma gondii thioredoxin reductase 0.0151 0.0981 0.1731
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0222 0.15 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.0943 0.6236
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.004 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.004 0.004
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.0483 0.0483
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.004 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0022 0.004 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.004 0.004
Giardia lamblia Kinase, CMGC MAPK 0.0222 0.15 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium ulcerans bacterioferritin BfrB 0.0086 0.0505 0.0858
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Mycobacterium tuberculosis Probable reductase 0.0345 0.2392 0.3565
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.0483 0.0483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0165
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0022 0.004 0.004
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0073 0.0073
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0943 0.0943
Schistosoma mansoni cpg binding protein 0.0067 0.0366 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0164 0.0229
Brugia malayi Smad1 0.0068 0.0378 0.0526
Echinococcus multilocularis thioredoxin glutathione reductase 0.0151 0.0981 0.0981
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0052 0.0262 0.0462
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0219 0.1459
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Brugia malayi Bromodomain containing protein 0.003 0.0098 0.0137
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.004 0.007
Echinococcus granulosus lamin dm0 0.0134 0.0858 0.0858
Onchocerca volvulus 0.0047 0.0226 0.0595
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.047 0.047
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0345 0.2392 0.3565
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0021 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0352 0.0352
Brugia malayi hypothetical protein 0.0233 0.1575 0.2191
Schistosoma mansoni peptidase 0.0024 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma cruzi trypanothione reductase, putative 0.0151 0.0981 0.6543
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.0483 0.0672
Schistosoma mansoni smad 0.0031 0.0103 0.0103
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0073 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0021 0.009
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0052 0.0262 0.0262
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0068 0.0378 0.0378
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0189 0.1255 0.2185
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0134 0.0858 0.1193
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi conserved hypotetical protein 0.0039 0.0164 0.0229
Schistosoma mansoni ferritin 0.0086 0.0505 0.0505
Giardia lamblia Hypothetical protein 0.0022 0.004 0.0128
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0189 0.1255 0.8368
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0052 0.0262 0.0262
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0069 0.0382 0.0531
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0298 0.1985
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.01 0.0263
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.004 0.0128
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0262 0.1744
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0219 0.0304
Loa Loa (eye worm) RNA binding protein 0.0462 0.3247 0.4516
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0239 0.1596
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.004 0.0172
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0022 0.004 0.004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0404 0.0562
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0151 0.0981 0.1444
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0073 0.0073
Schistosoma mansoni nuclear receptor 0.0039 0.0164 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.004 0.004
Echinococcus multilocularis GPCR, family 2 0.0081 0.047 0.047
Onchocerca volvulus 0.0146 0.0943 0.2487
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0355 0.0626
Onchocerca volvulus 0.0034 0.0131 0.0346
Echinococcus multilocularis chromobox protein 1 0.0078 0.0451 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Brugia malayi MAP kinase sur-1 0.0222 0.15 0.2086
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0052 0.0262 0.1629
Loa Loa (eye worm) hypothetical protein 0.0175 0.1156 0.1608
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Echinococcus granulosus mothers against decapentaplegic 5 0.0068 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.004 0.004
Brugia malayi Isocitrate dehydrogenase 0.0068 0.0372 0.0518
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0052 0.0262 0.1744
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0022 0.004 0.004
Brugia malayi follicle stimulating hormone receptor 0.0501 0.3533 0.4914
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0222 0.15 1
Schistosoma mansoni lamin 0.0134 0.0858 0.0858
Schistosoma mansoni thyroid hormone receptor 0.1114 0.7995 0.7995
Schistosoma mansoni chromobox protein 0.0078 0.0451 0.0451
Trichomonas vaginalis mercuric reductase, putative 0.0052 0.0262 0.069
Onchocerca volvulus Alhambra homolog 0.003 0.0098 0.026
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0052 0.0262 0.0262
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0022 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni tar DNA-binding protein 0.0462 0.3247 0.3247
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0078 0.0205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0164 0.0164
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.0483 0.0483
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0932 0.6672 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0219 0.1459
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0164 0.0164
Schistosoma mansoni jumonji domain containing protein 0.0141 0.0908 0.0908
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0022 0.004 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0022 0.004 0.004
Brugia malayi Animal haem peroxidase family protein 0.0358 0.2489 0.3462
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Brugia malayi tailless protein 0.0039 0.0164 0.0229
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0834 0.5958 0.5958
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0199 0.0199
Echinococcus granulosus ubiquitin specific protease 41 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Echinococcus granulosus phd:f box containing protein 0.0027 0.0073 0.0073
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0098 0.0174
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.0483 0.0483
Brugia malayi MH2 domain containing protein 0.0031 0.0103 0.0143
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.0483 0.1274
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0199 0.0276
Plasmodium falciparum glutathione reductase 0.0052 0.0262 0.0462
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.004 0.004
Loa Loa (eye worm) intermediate filament protein 0.0134 0.0858 0.1193
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0164 0.0164
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0052 0.0262 0.1629
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.0483 0.0483
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0021 0.0055
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0169 0.0446
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0022 0.004 0.004
Plasmodium falciparum thioredoxin reductase 0.0151 0.0981 0.1731
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.004 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0483 0.0483
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.047 0.0654
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0521 0.3674 0.6137
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.0483 0.0672
Brugia malayi Ets-domain containing protein 0.0073 0.0411 0.0571
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.0483 0.0483
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0099 0.0099
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0262 0.1744
Loa Loa (eye worm) animal heme peroxidase 0.0358 0.2489 0.3462
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.004 0.004
Schistosoma mansoni ap endonuclease 0.0019 0.0021 0.0021
Mycobacterium tuberculosis Probable oxidoreductase 0.0383 0.2673 0.3987
Onchocerca volvulus 0.0146 0.0943 0.2487
Echinococcus granulosus chromobox protein 1 0.0078 0.0451 0.0451
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0065 0.0352 0.049
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.0943 0.1386
Echinococcus granulosus mitogen activated protein kinase 0.0222 0.15 0.15
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Schistosoma mansoni transcription factor LCR-F1 0.0335 0.2319 0.2319
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0052 0.0262 0.0426
Brugia malayi ecdysone receptor 0.0039 0.0164 0.0229
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0021 0.0029
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0372 0.2376
Brugia malayi mothers against decapentaplegic homolog 3 0.0031 0.0103 0.0143
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0098 0.0098
Trichomonas vaginalis glutathione reductase, putative 0.0052 0.0262 0.069
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Toxoplasma gondii hypothetical protein 0.0022 0.004 0.007
Brugia malayi hypothetical protein 0.0044 0.0199 0.0276
Plasmodium vivax SET domain protein, putative 0.0069 0.0382 0.0674
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0078 0.0205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Echinococcus granulosus mothers against decapentaplegic 6 0.0031 0.0103 0.0103
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0795 0.5668 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0022 0.004 0.004
Leishmania major cathepsin L-like protease 0.0063 0.0337 0.2249
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Brugia malayi beta-lactamase family protein 0.0146 0.0943 0.1312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus Smad4 0.0068 0.0378 0.0378
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.004 0.0105
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0355 0.0355
Schistosoma mansoni hypothetical protein 0.0081 0.047 0.047
Echinococcus multilocularis expressed protein 0.0022 0.004 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0382 0.0382
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0052 0.0262 0.0426
Loa Loa (eye worm) hypothetical protein 0.0038 0.0155 0.0216
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0483 0.0483
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.015 0.0872
Brugia malayi Animal haem peroxidase family protein 0.0358 0.2489 0.3462
Schistosoma mansoni chromobox protein 0.0078 0.0451 0.0451
Schistosoma mansoni tar DNA-binding protein 0.0462 0.3247 0.3247
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.004 0.004
Schistosoma mansoni Smad4 0.0031 0.0103 0.0103
Mycobacterium tuberculosis Probable dehydrogenase 0.0345 0.2392 0.3565
Echinococcus granulosus peregrin 0.003 0.0098 0.0098
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0335 0.2319 0.2319
Loa Loa (eye worm) TAR-binding protein 0.0462 0.3247 0.4516
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.016 0.0223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.013
Toxoplasma gondii NADPH-glutathione reductase 0.0052 0.0262 0.0462
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.004 0.004
Echinococcus multilocularis chromobox protein 1 0.0078 0.0451 0.0451
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni hypothetical protein 0.0081 0.047 0.047
Brugia malayi Blistered cuticle protein 3 0.0358 0.2489 0.3462
Brugia malayi ubiquitin specific protease 14 0.0022 0.004 0.0055
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.004 0.004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0073 0.0073
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0372 0.0372
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0073 0.0129
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0022 0.004 0.004
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0355 0.0502
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.004 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0086 0.0505 0.0728
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0022 0.004 0.007
Schistosoma mansoni survival motor neuron protein 0.0047 0.0226 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Brugia malayi CXXC zinc finger family protein 0.0063 0.034 0.0473
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Schistosoma mansoni thyroid hormone receptor 0.1114 0.7995 0.7995
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0483 0.0483
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.0382 0.0382
Schistosoma mansoni zinc finger protein 0.0039 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0052 0.0262 0.0426
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0382 0.0382
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0029 0.0078
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0143
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0795 0.5668 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0052 0.0262 0.0462
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0073 0.0073
Schistosoma mansoni cpg binding protein 0.0067 0.0366 0.0366
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0164 0.0434
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0084 0.0084
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.004 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0164 0.0164
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0164 0.0229
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.0943 0.1386
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Loa Loa (eye worm) MH2 domain-containing protein 0.0068 0.0378 0.0526
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Schistosoma mansoni hypothetical protein 0.0335 0.2319 0.2319
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.0483 0.0483
Brugia malayi Intermediate filament tail domain containing protein 0.0134 0.0858 0.1193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0073 0.0102
Brugia malayi glutathione reductase 0.0151 0.0981 0.1365
Brugia malayi ecdysteroid receptor 0.0083 0.0483 0.0672
Schistosoma mansoni hypothetical protein 0.0175 0.1156 0.1156
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.004 0.004
Brugia malayi hypothetical protein 0.0335 0.2319 0.3226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0078 0.0205
Schistosoma mansoni gabp alpha 0.0073 0.0411 0.0411
Echinococcus multilocularis lamin 0.0134 0.0858 0.0858
Schistosoma mansoni jumonji/arid domain-containing protein 0.0103 0.0631 0.0631
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0146 0.0943 0.1312
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.047 0.0654
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0022 0.004 0.004
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0345 0.2392 0.3565
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0164 0.0229
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Brugia malayi TAR-binding protein 0.0462 0.3247 0.4516
Onchocerca volvulus 0.0134 0.0858 0.2262
Brugia malayi beta-lactamase family protein 0.0146 0.0943 0.1312
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0199 0.0276
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0943 0.2487
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0149 0.0394
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0022 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni peroxidasin 0.0358 0.2489 0.2489
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis mitogen activated protein kinase 3 0.0222 0.15 0.15
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Onchocerca volvulus 0.0022 0.004 0.0105
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.0483 0.0672
Echinococcus granulosus mitogen activated protein kinase 3 0.0222 0.15 0.15
Echinococcus granulosus geminin 0.0191 0.127 0.127
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0078
Onchocerca volvulus 0.0039 0.0164 0.0434
Loa Loa (eye worm) Smad1 0.0068 0.0378 0.0526
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.1031 0.7392 0.7392
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0021 0.0021
Echinococcus multilocularis smad 0.0068 0.0378 0.0378
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0022 0.004 0.004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0372 0.2481
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium leprae Probable lipase LipE 0.0146 0.0943 0.0848
Onchocerca volvulus Peroxidase homolog 0.0358 0.2489 0.6563
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0337 0.2249
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0021 0.0139
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0383 0.2673 0.3987
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.004 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0219 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.0943 0.1386
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Brugia malayi nuclear receptor NHR-88 0.0083 0.0483 0.0672
Echinococcus multilocularis peroxidasin 0.0358 0.2489 0.2489
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0052 0.0262 0.0362
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0073 0.0102
Loa Loa (eye worm) beta-lactamase 0.0146 0.0943 0.1312
Brugia malayi MH1 domain containing protein 0.0068 0.0378 0.0526
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0021 0.0139
Schistosoma mansoni Smad4 0.0068 0.0378 0.0378
Onchocerca volvulus Dual oxidase homolog 0.0358 0.2489 0.6563
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0022 0.004 0.004
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0022 0.004 0.004
Brugia malayi Heterochromatin protein 1 0.0078 0.0451 0.0628
Echinococcus multilocularis mothers against decapentaplegic 6 0.0031 0.0103 0.0103
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0022 0.004 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0022 0.0058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0372 0.0372
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0068 0.0372 0.2376
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0164 0.0164
Toxoplasma gondii hypothetical protein 0.0274 0.1874 0.3306
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0256 0.1746 0.2429
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni hypothetical protein 0.0022 0.004 0.004
Echinococcus multilocularis neuropeptide s receptor 0.0459 0.322 0.322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0022 0.004 0.004
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0022 0.004 0.004
Mycobacterium tuberculosis Conserved protein 0.0146 0.0943 0.1386
Loa Loa (eye worm) fli-1 protein 0.0221 0.1492 0.2075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.0483 0.0672
Loa Loa (eye worm) hypothetical protein 0.0027 0.0073 0.0102
Leishmania major hypothetical protein, conserved 0.0027 0.0073 0.0488
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0098 0.0098
Schistosoma mansoni ferritin light chain 0.0086 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0044 0.0199 0.0276
Giardia lamblia GTOR 0.0047 0.0219 0.1338
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.0483 0.1274
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0462 0.3247 0.4516
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0225 0.0592
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus tumor protein p63 0.0348 0.2413 0.2413
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi hypothetical protein 0.0022 0.004 0.0055
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0164 0.0164
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0795 0.5668 0.5668
Loa Loa (eye worm) glutathione reductase 0.0151 0.0981 0.1365
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Echinococcus granulosus thioredoxin glutathione reductase 0.0151 0.0981 0.0981
Echinococcus granulosus ubiquitin specific peptidase c family 0.0022 0.004 0.004
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0189 0.1255 0.1255
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0355 0.0355
Echinococcus granulosus lysine specific demethylase 5A 0.0103 0.0631 0.0631
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0219 0.1459
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0184 0.0184
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.02 0.0528
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.0483 0.0483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0217
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0098 0.0137
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0164 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi Fli-1 protein 0.0221 0.1492 0.2075
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.004 0.0055
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.004 0.0132
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0274 0.1874 0.3306
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.004 0.004
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0345 0.2392 0.3655
Schistosoma mansoni tar DNA-binding protein 0.0462 0.3247 0.3247
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.0483 0.0672
Onchocerca volvulus Peroxidasin homolog 0.0358 0.2489 0.6563
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0217
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0483 0.0483
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0222 0.15 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0164 0.0164
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.004 0.007
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.015 0.0998
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.0483 0.0483
Mycobacterium ulcerans beta-lactamase 0.0146 0.0943 0.1633
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0451 0.119
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.0483 0.1274
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0943 0.1664
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0086 0.0505 0.0858
Echinococcus multilocularis lamin dm0 0.0134 0.0858 0.0858
Trichomonas vaginalis CMGC family protein kinase 0.0222 0.15 0.3954
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0262 0.1629
Schistosoma mansoni peptidase Clp (S14 family) 0.0795 0.5668 0.5668
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0451 0.0628
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0521 0.3674 0.5492
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.0483 0.0483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Schistosoma mansoni hypothetical protein 0.09 0.6434 0.6434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0483 0.0672
Echinococcus multilocularis cpg binding protein 0.0067 0.0366 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Loa Loa (eye worm) histone methyltransferase 0.0022 0.004 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0012 0.0012
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0222 0.15 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0031 0.0103 0.0143
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0021 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0219 0.0577
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0164 0.0229
Onchocerca volvulus 0.0082 0.0475 0.1253
Echinococcus granulosus lamin 0.0134 0.0858 0.0858
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Loa Loa (eye worm) DR-78 0.0039 0.0164 0.0229
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0483 0.0483
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Echinococcus granulosus chromobox protein 1 0.0078 0.0451 0.0451
Brugia malayi nuclear receptor RXR 0.0044 0.0199 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0068 0.0372 0.0372
Echinococcus granulosus neuropeptide s receptor 0.0459 0.322 0.322
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0251 0.0251
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0022 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0107 0.0283
Plasmodium vivax ubiquitin specific protease, putative 0.0022 0.004 0.007
Schistosoma mansoni smad1 5 8 and 0.0068 0.0378 0.0378
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0149 0.0394
Loa Loa (eye worm) jmjC domain-containing protein 0.0103 0.0631 0.0877
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi intermediate filament protein 0.0134 0.0858 0.1193
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.0943 0.1312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Onchocerca volvulus Chorion peroxidase homolog 0.0358 0.2489 0.6563
Schistosoma mansoni hypothetical protein 0.0081 0.047 0.047
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0222 0.15 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0165
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.0483 0.0672
Trichomonas vaginalis CMGC family protein kinase 0.0222 0.15 0.3954
Loa Loa (eye worm) hypothetical protein 0.0795 0.5668 0.7884
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0073 0.0073
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0022 0.004 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.0483 0.0672
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0149 0.0394
Loa Loa (eye worm) hypothetical protein 0.0044 0.0199 0.0276
Brugia malayi Calcitonin receptor-like protein seb-1 0.0256 0.1746 0.2429
Schistosoma mansoni ferritin light chain 0.0086 0.0505 0.0505
Schistosoma mansoni ferritin 0.0086 0.0505 0.0505
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0274 0.1874 0.3282
Trichomonas vaginalis set domain proteins, putative 0.0537 0.3793 1
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.0943 0.1386
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0345 0.2392 0.3565
Echinococcus granulosus GPCR family 2 0.0081 0.047 0.047
Brugia malayi Animal haem peroxidase family protein 0.0358 0.2489 0.3462
Brugia malayi jmjC domain containing protein 0.0161 0.1056 0.1468
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0256 0.1746 0.2429
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0065 0.0354 0.0354
Echinococcus multilocularis mothers against decapentaplegic 5 0.0068 0.0378 0.0378
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0146 0.0943 0.1312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0073 0.0102
Brugia malayi nuclear receptor NHR-67 0.0039 0.0164 0.0229
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.0483 0.0483
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.0382 0.0674
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.0943 0.1386
Brugia malayi nuclear receptor RXR 0.0039 0.0164 0.0229
Schistosoma mansoni smad1 5 8 and 0.0068 0.0378 0.0378
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.004 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0022 0.004 0.004
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0146 0.0943 0.1312
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0382 0.0382
Brugia malayi jmjC domain containing protein 0.0027 0.0073 0.0102
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Loa Loa (eye worm) hypothetical protein 0.0132 0.084 0.1169
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0078 0.0205
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0164 0.0164
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0355 0.0355
Loa Loa (eye worm) MH1 domain-containing protein 0.0068 0.0378 0.0526
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Treponema pallidum bacterioferrin (TpF1) 0.0086 0.0505 0.0858
Brugia malayi Pre-SET motif family protein 0.0069 0.0382 0.0531
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0795 0.5668 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.011 0.0153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis peregrin 0.003 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Plasmodium vivax JmjC domain containing protein 0.0027 0.0073 0.0129
Loa Loa (eye worm) hypothetical protein 0.0256 0.1746 0.2429
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0219 0.0219
Brugia malayi Probable ClpP-like protease 0.0795 0.5668 0.7884
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Onchocerca volvulus 0.0063 0.034 0.0897
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0355 0.2365
Echinococcus multilocularis ubiquitin specific protease 41 0.0022 0.004 0.004
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0355 0.0355
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.0483 0.0483
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0383 0.2673 0.3987
Schistosoma mansoni hypothetical protein 0.003 0.0098 0.0098
Toxoplasma gondii ubiquitin-specific protease USP4 0.0022 0.004 0.007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.0483 0.0672
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0052 0.0262 0.0462
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0073 0.0073
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Echinococcus multilocularis isocitrate dehydrogenase 0.0068 0.0372 0.0372
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.007
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0199 0.0276
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0137
Echinococcus granulosus tar DNA binding protein 0.0462 0.3247 0.3247
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0073 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0082 0.0475 0.0475
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.0483 0.0483
Echinococcus granulosus mothers against decapentaplegic 2 0.0031 0.0103 0.0103
Treponema pallidum NADH oxidase 0.0052 0.0262 0.0426
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0098 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Brugia malayi MH2 domain containing protein 0.1003 0.719 1
Echinococcus multilocularis neuropeptide receptor A26 0.0459 0.322 0.322
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0372 0.0657
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.004 0.0105
Schistosoma mansoni intermediate filament proteins 0.0134 0.0858 0.0858
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0078 0.0205
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0337 0.2249
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0795 0.5668 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0251 0.0349
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0411 0.0411
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.034 0.0473
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0052 0.0262 0.0426
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0199 0.0199
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0189 0.1255 0.1746
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0164 0.0164
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Schistosoma mansoni Smad4 0.0031 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0149 0.0394
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.15 0.15
Plasmodium vivax hypothetical protein, conserved 0.0022 0.004 0.007
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0189 0.1255 0.1255
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0073 0.0488
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Echinococcus multilocularis geminin 0.0191 0.127 0.127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Loa Loa (eye worm) hypothetical protein 0.0134 0.0858 0.1193
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.004 0.004
Brugia malayi MH1 domain containing protein 0.0038 0.0155 0.0216
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0073 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0166
Echinococcus granulosus intermediate filament protein 0.0134 0.0858 0.0858
Schistosoma mansoni cpg binding protein 0.0063 0.034 0.034
Onchocerca volvulus 0.0358 0.2489 0.6563
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Echinococcus granulosus peptidase Clp S14 family 0.0521 0.3674 0.3674
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0081 0.047 0.0654
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0164 0.0164
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0262 0.1744
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0164 0.0229
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.008 0.0212
Trichomonas vaginalis ferritin, putative 0.0086 0.0505 0.1333
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0355 0.0591
Brugia malayi PHD-finger family protein 0.003 0.0098 0.0137
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0021 0.0139
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0404 0.0562
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0068 0.0372 0.0372
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0222 0.15 0.2646
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0073 0.0129
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Loa Loa (eye worm) hypothetical protein 0.0068 0.0377 0.0525
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.007
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Brugia malayi beta-lactamase 0.0146 0.0943 0.1312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis mitogen activated protein kinase 0.0222 0.15 0.15
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0132 0.0233
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Schistosoma mansoni smad1 5 8 and 0.0068 0.0378 0.0378
Onchocerca volvulus Peroxidasin homolog 0.0358 0.2489 0.6563
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0022 0.004 0.004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0164 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0189 0.1255 0.1255
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0073 0.0073
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.0382 0.0382
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0501 0.3533 0.4914
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.016 0.0223
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0068 0.0372 0.0657
Schistosoma mansoni lamin 0.0134 0.0858 0.0858
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.0483 0.0483
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0078 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0483 0.0672
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.0943 0.1386
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0022 0.004 0.007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0219 0.0577
Toxoplasma gondii histone lysine methyltransferase SET1 0.0122 0.077 0.1358
Giardia lamblia PHD finger protein 15 0.003 0.0098 0.0524
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0146 0.0943 0.1312
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0521 0.3674 0.5492
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0262 0.1629
Onchocerca volvulus 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.004 0.007
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0225 0.0592
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.007
Entamoeba histolytica hypothetical protein 0.0335 0.2319 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0483 0.0672
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.0483 0.0672
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.004 0.0105
Brugia malayi Animal haem peroxidase family protein 0.0358 0.2489 0.3462
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0052 0.0262 0.0462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.02 0.0528
Mycobacterium leprae conserved hypothetical protein 0.0146 0.0943 0.0848
Entamoeba histolytica hypothetical protein 0.0022 0.004 0.0172
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0219 0.1459
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0078 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.0483 0.0672
Loa Loa (eye worm) hypothetical protein 0.0146 0.0943 0.1312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.0382 0.0382
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.0483 0.0483
Brugia malayi jmjC domain containing protein 0.0027 0.0073 0.0102
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0052 0.0262 0.0462
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0219 0.0943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0165
Brugia malayi isocitrate dehydrogenase 0.0068 0.0372 0.0518
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0483 0.0672
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Brugia malayi Animal haem peroxidase family protein 0.0358 0.2489 0.3462
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Mycobacterium tuberculosis Conserved protein 0.0146 0.0943 0.1386
Schistosoma mansoni ap endonuclease 0.0019 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0335 0.2319 1
Echinococcus multilocularis mothers against decapentaplegic 2 0.0031 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Giardia lamblia NADH oxidase lateral transfer candidate 0.0052 0.0262 0.1628
Echinococcus multilocularis microtubule associated protein 2 0.1389 1 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0073 0.0488
Schistosoma mansoni smad 0.0068 0.0378 0.0378
Plasmodium falciparum thioredoxin reductase 0.0052 0.0262 0.0462
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0022 0.004 0.004
Brugia malayi hypothetical protein 0.0039 0.0164 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.047 0.047
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.02 0.0528
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Echinococcus granulosus TGF beta signal transducer SmadC 0.0068 0.0378 0.0378
Schistosoma mansoni apoferritin-2 0.0086 0.0505 0.0505
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0078 0.0205
Loa Loa (eye worm) animal heme peroxidase 0.0358 0.2489 0.3462
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0022 0.004 0.004
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0184 0.0184
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0943 0.2487
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.004 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0022 0.004 0.004
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0164 0.0164
Onchocerca volvulus Peroxidase homolog 0.0358 0.2489 0.6563
Brugia malayi chromobox protein homolog 3 0.0044 0.02 0.0279
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0943 0.0943
Brugia malayi latrophilin 2 splice variant baaae 0.0175 0.1156 0.1608
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.004 0.0055
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0274 0.1874 0.3306
Echinococcus multilocularis Smad4 0.0068 0.0378 0.0378
Echinococcus multilocularis ferritin 0.0086 0.0505 0.0505
Loa Loa (eye worm) animal heme peroxidase 0.0358 0.2489 0.3462
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0262 0.1744
Loa Loa (eye worm) MH2 domain-containing protein 0.1003 0.719 1
Schistosoma mansoni hypothetical protein 0.0047 0.0226 0.0226
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0068 0.0372 0.2481
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.004 0.007
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0022 0.004 0.004
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.004 0.0266
Brugia malayi hypothetical protein 0.0044 0.0199 0.0276
Echinococcus granulosus ferritin 0.0086 0.0505 0.0505
Plasmodium vivax thioredoxin reductase, putative 0.0151 0.0981 0.1731
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0132 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0483 0.0672
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.004 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0943 0.6288
Onchocerca volvulus 0.0039 0.0164 0.0434
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.004 0.007
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0098 0.0098
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0274 0.1874 0.2651
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0383 0.2673 0.4198
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0164 0.0229
Brugia malayi MH2 domain containing protein 0.0068 0.0378 0.0526
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0943 0.2487
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0189 0.1255 0.2185
Loa Loa (eye worm) hypothetical protein 0.0062 0.0334 0.0465
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0176 0.1163 0.1617
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0331 0.0461
Echinococcus multilocularis expressed protein 0.0086 0.0505 0.0505
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0161 0.1056 0.1056
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Toxoplasma gondii exonuclease III APE 0.0019 0.0021 0.0037
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.004 0.0128
Loa Loa (eye worm) thioredoxin reductase 0.0151 0.0981 0.1365
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Schistosoma mansoni peroxidasin 0.0358 0.2489 0.2489
Schistosoma mansoni hypothetical protein 0.1031 0.7392 0.7392
Schistosoma mansoni tar DNA-binding protein 0.0462 0.3247 0.3247
Echinococcus granulosus dnaJ subfamily B 0.09 0.6434 0.6434
Brugia malayi jmjC domain containing protein 0.0027 0.0073 0.0102
Plasmodium vivax glutathione reductase, putative 0.0151 0.0981 0.1731
Echinococcus granulosus peroxidasin 0.0358 0.2489 0.2489
Schistosoma mansoni hypothetical protein 0.0191 0.127 0.127
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0073 0.0129
Loa Loa (eye worm) transcription factor SMAD2 0.1003 0.719 1
Echinococcus granulosus cpg binding protein 0.0067 0.0366 0.0366
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0022 0.004 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Schistosoma mansoni ets-related 0.0221 0.1492 0.1492
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0337 0.2249
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Schistosoma mansoni hypothetical protein 0.0191 0.127 0.127
Echinococcus granulosus smad 0.0068 0.0378 0.0378
Onchocerca volvulus 0.0358 0.2489 0.6563
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.004 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.0483 0.0672
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.004 0.004
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.004 0.0128
Brugia malayi nuclear hormone receptor 0.0083 0.0483 0.0672
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0164 0.0164
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0345 0.2392 0.3565
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Entamoeba histolytica hypothetical protein 0.0335 0.2319 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0199 0.0276
Schistosoma mansoni coup transcription factor 0.0083 0.0483 0.0483
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0136 0.0874 0.0874
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0063 0.0166
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni microtubule-associated protein tau 0.1389 1 1
Leishmania major hypothetical protein, conserved 0.0146 0.0943 0.6288
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0219 0.0943
Onchocerca volvulus 0.0146 0.0943 0.2487
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0068 0.0372 0.0528
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0222 0.15 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.008 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.0483 0.0672
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.0483 0.0483
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0073 0.0354
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Onchocerca volvulus 0.0537 0.3793 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0337 0.2141
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0226 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0149 0.0394
Plasmodium falciparum glutathione reductase 0.0151 0.0981 0.1731
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0795 0.5668 1
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0337 0.2249
Leishmania major cathepsin L-like protease 0.0063 0.0337 0.2249
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.004 0.004
Brugia malayi Peroxidasin 0.0358 0.2489 0.3462
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0411 0.0411
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.015 0.0998
Loa Loa (eye worm) hypothetical protein 0.0233 0.1575 0.2191
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0372 0.0372
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0021 0.0055
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0335 0.2319 0.2319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.004 0.0172
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0355 0.0591
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.004 0.004
Plasmodium falciparum phd finger protein, putative 0.003 0.0098 0.0174
Loa Loa (eye worm) hypothetical protein 0.0083 0.0483 0.0672
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0031 0.0103 0.027
Leishmania major trypanothione reductase 0.0151 0.0981 0.6543
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0219 0.0219
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0052 0.0262 0.0426
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.0266
Brugia malayi nuclear hormone receptor 0.0039 0.0164 0.0229
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0411 0.0571
Toxoplasma gondii ABC1 family protein 0.0146 0.0943 0.1664
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0022 0.004 0.004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0225 0.0592
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0462 0.3247 0.3247
Mycobacterium ulcerans bacterioferritin BfrA 0.0086 0.0505 0.0858
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.0943 0.1312
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0021 0.0021
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0086 0.0505 0.0728
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0164 0.0229
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Schistosoma mansoni apoferritin-2 0.0086 0.0505 0.0505
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Onchocerca volvulus 0.0022 0.004 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus multilocularis dnaJ subfamily B 0.09 0.6434 0.6434
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0355 0.0591
Trypanosoma brucei protein kinase, putative 0.0222 0.15 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0164 0.0164
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.047 0.047
Echinococcus granulosus FTZ F1 alpha 0.0083 0.0483 0.0483
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0052 0.0262 0.1744
Echinococcus granulosus expressed protein 0.0086 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0034 0.0131 0.0182
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0451 0.119
Loa Loa (eye worm) animal heme peroxidase 0.0358 0.2489 0.3462
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Trichomonas vaginalis CMGC family protein kinase 0.0222 0.15 0.3954
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0022 0.004 0.004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0164 0.0229
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0022 0.004 0.004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.004 0.013
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.0943 0.0943
Schistosoma mansoni nuclear hormone receptor 0.0083 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0358 0.2489 0.3462
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.0943 0.0943
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229
Brugia malayi MH1 domain containing protein 0.0068 0.0378 0.0526
Brugia malayi jmjC domain containing protein 0.0103 0.0631 0.0877
Brugia malayi hypothetical protein 0.0358 0.2489 0.3462
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.004 0.0266
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0472 0.3319 0.4617
Loa Loa (eye worm) blistered cuticle protein 3 0.0358 0.2489 0.3462
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0073 0.0102
Onchocerca volvulus 0.0134 0.0858 0.2262
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.004 0.0055
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0052 0.0262 0.0364
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0199 0.0199
Echinococcus multilocularis musashi 0.0134 0.0858 0.0858
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0055
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0022 0.004 0.004
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.0483 0.0483
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.004 0.0105
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.0483 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.004 0.0105
Schistosoma mansoni hypothetical protein 0.0081 0.047 0.047
Loa Loa (eye worm) hypothetical protein 0.0039 0.0164 0.0229

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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