Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.1673 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.3562 | 0.3972 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.1418 | 0.1358 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0418 | 0.014 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.1673 | 0.1309 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.1418 | 0.1043 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1974 | 0.1825 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0303 | 0.0808 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.1673 | 0.1673 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.3028 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.33 | 0.3651 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0692 | 0.0285 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.1673 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0692 | 0.0473 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.1185 | 0.1185 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.046 | 0.0191 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.851 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0303 | 0.0808 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.1418 | 0.1043 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0887 | 0.0711 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.1042 | 0.1042 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.1673 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0887 | 0.0489 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.1418 | 0.1358 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.3327 | 0.3036 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1673 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.1673 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2207 | 0.2062 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0418 | 0.014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.046 | 0.0191 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.1673 | 0.1518 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.1659 | 0.1294 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0887 | 0.0489 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0654 | 0.0427 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.1673 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.1673 | 0.1669 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.046 | 0.0043 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.1673 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.1673 | 0.1309 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0013 | 0.0183 | 0.0183 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.1185 | 0.1074 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0692 | 0.0285 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0459 | 0.0281 |
Onchocerca volvulus | 0.0028 | 0.1185 | 0.1889 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.3327 | 0.3036 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.1673 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.3944 | 0.3831 |
Onchocerca volvulus | 0.0093 | 0.5488 | 1 | |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.851 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.4332 | 0.4332 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0654 | 0.048 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.1673 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1673 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0303 | 0.0808 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.1673 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.1673 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.1673 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.1659 | 0.1294 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.1185 | 0.1021 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.1673 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.1814 | 0.1814 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.1673 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.046 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1819 | 0.1666 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.046 | 0.0043 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0303 | 0.0808 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.