Detailed information for compound 762545

Basic information

Technical information
  • TDR Targets ID: 762545
  • Name: ethyl 4-[[1-(3,4-dimethoxyphenyl)cyclopentane carbonyl]amino]benzoate
  • MW: 397.464 | Formula: C23H27NO5
  • H donors: 1 H acceptors: 2 LogP: 4.28 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1ccc(cc1)NC(=O)C1(CCCC1)c1ccc(c(c1)OC)OC
  • InChi: 1S/C23H27NO5/c1-4-29-21(25)16-7-10-18(11-8-16)24-22(26)23(13-5-6-14-23)17-9-12-19(27-2)20(15-17)28-3/h7-12,15H,4-6,13-14H2,1-3H3,(H,24,26)
  • InChiKey: FCKNOBHSGKAILO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[[[1-(3,4-dimethoxyphenyl)cyclopentyl]-oxomethyl]amino]benzoic acid ethyl ester
  • 4-[[1-(3,4-dimethoxyphenyl)cyclopentanecarbonyl]amino]benzoic acid ethyl ester
  • ethyl 4-[[1-(3,4-dimethoxyphenyl)cyclopentyl]carbonylamino]benzoate
  • Oprea1_171132
  • AJ-292/15302098
  • ZINC00892569
  • BAS 03026604
  • UNM000000624201
  • Oprea1_202426
  • EU-0077406

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine methyltransferase SET1 0.0395 0.1263 0.4393
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Echinococcus multilocularis isocitrate dehydrogenase 0.0129 0.0348 0.0344
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0118 0.0225
Trichomonas vaginalis glucosylceramidase, putative 0.0902 0.3008 0.6821
Brugia malayi MH1 domain containing protein 0.0041 0.0043 0.0078
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0116 0.0112
Entamoeba histolytica hypothetical protein 0.0035 0.0024 0.01
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0437 0.1407 0.1407
Brugia malayi isocitrate dehydrogenase 0.0129 0.0348 0.0683
Loa Loa (eye worm) hypothetical protein 0.0098 0.0239 0.0466
Brugia malayi Cytochrome P450 family protein 0.0051 0.0078 0.0146
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0118 0.0113
Echinococcus granulosus geminin 0.1899 0.6436 0.6434
Loa Loa (eye worm) ICD-1 protein 0.0138 0.0379 0.0744
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0024 0.0024
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0035 0.5
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.033 0.1037 0.2052
Loa Loa (eye worm) hypothetical protein 0.0033 0.0016 0.0024
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0116 0.0116
Trichomonas vaginalis helicase, putative 0.0047 0.0064 0.0066
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0062 0.0143
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0851 0.283 0.6412
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0118 0.0225
Loa Loa (eye worm) hypothetical protein 0.007 0.0146 0.0281
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0035 0.0048
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.0114
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0152 0.0148
Brugia malayi MH2 domain containing protein 0.0599 0.1963 0.3889
Brugia malayi RNA recognition motif domain containing protein 0.0252 0.0771 0.1522
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.0114
Echinococcus multilocularis transcription factor btf3 0.0138 0.0379 0.0375
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0118 0.0118
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0129 0.0348 0.1203
Schistosoma mansoni zinc finger protein 0.0031 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0771 0.0771
Brugia malayi latrophilin 2 splice variant baaae 0.0519 0.169 0.3348
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0062 0.0143
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0252 0.0771 0.1522
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0146 0.0141
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0062 0.0258
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0129 0.0348 0.1203
Loa Loa (eye worm) histone methyltransferase 0.0064 0.0122 0.0235
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0274 0.0845 0.2963
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0118 0.0113
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0024 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Loa Loa (eye worm) hypothetical protein 0.0438 0.1409 0.2789
Trypanosoma brucei transcription factor BTF3, putative 0.0138 0.0379 0.1311
Schistosoma mansoni hypothetical protein 0.0305 0.0951 0.0951
Onchocerca volvulus 0.007 0.0146 0.0497
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0073 0.0155 0.0429
Echinococcus granulosus zinc finger protein 0.0051 0.0079 0.0075
Echinococcus multilocularis zinc finger protein 0.0051 0.0079 0.0075
Onchocerca volvulus 0.0191 0.0559 0.195
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0078 0.0146
Echinococcus multilocularis survival motor neuron protein 1 0.1493 0.5039 0.5037
Echinococcus granulosus histone lysine methyltransferase setb 0.0039 0.0037 0.0032
Brugia malayi PHD-finger family protein 0.0062 0.0116 0.0222
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0073 0.0155 0.0299
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0146 0.0909
Brugia malayi Latrophilin receptor protein 2 0.024 0.073 0.1442
Mycobacterium tuberculosis Conserved protein 0.007 0.0146 0.0909
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0039 0.0037 0.0037
Brugia malayi nuclear receptor RXR 0.0033 0.0016 0.0024
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0851 0.283 0.2826
Brugia malayi Bromodomain containing protein 0.0163 0.0463 0.0911
Entamoeba histolytica transcription factor BTF3, putative 0.0138 0.0379 0.159
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0116 0.0112
Schistosoma mansoni smad1 5 8 and 0.0041 0.0043 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0146 0.0254
Onchocerca volvulus 0.007 0.0146 0.0497
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0146 0.0484
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0529 0.1043
Leishmania major alpha glucosidase II subunit, putative 0.0073 0.0155 0.0517
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0118 0.0225
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0146 0.0484
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0146 0.0909
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0021 0.0021
Echinococcus multilocularis microtubule associated protein 2 0.2259 0.7673 0.7672
Echinococcus granulosus neutral alpha glucosidase AB 0.0073 0.0155 0.0151
Brugia malayi glucose-6-phosphate dehydrogenase 0.0851 0.283 0.5611
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Schistosoma mansoni hypothetical protein 0.024 0.073 0.073
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0529 0.1043
Echinococcus multilocularis tar DNA binding protein 0.0252 0.0771 0.0767
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0118 0.0113
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 1
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0062 0.0114
Trichomonas vaginalis glucosylceramidase, putative 0.1305 0.4393 1
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0851 0.283 0.2826
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0035 0.0061
Brugia malayi jmjC domain containing protein 0.0062 0.0116 0.0222
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0305 0.0951 0.188
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0129 0.0348 0.0348
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0118 0.0118
Loa Loa (eye worm) pigment dispersing factor receptor c 0.076 0.2517 0.4991
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0146 0.0146
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0118 0.0113
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0129 0.0348 0.0344
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0118 0.0118
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0146 0.0254
Loa Loa (eye worm) hypothetical protein 0.007 0.0146 0.0281
Loa Loa (eye worm) hypothetical protein 0.0519 0.169 0.3348
Loa Loa (eye worm) hypothetical protein 0.0244 0.0742 0.1464
Schistosoma mansoni ap endonuclease 0.0038 0.0035 0.0035
Schistosoma mansoni smad1 5 8 and 0.0041 0.0043 0.0043
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0282 0.0873 0.3062
Schistosoma mansoni hypothetical protein 0.1899 0.6436 0.6436
Mycobacterium ulcerans beta-lactamase 0.007 0.0146 0.0442
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0118 0.0225
Trypanosoma brucei glucosidase, putative 0.0073 0.0155 0.0517
Mycobacterium ulcerans hypothetical protein 0.0046 0.0062 0.0143
Schistosoma mansoni hypothetical protein 0.0042 0.0046 0.0046
Onchocerca volvulus 0.0305 0.0951 0.3327
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0035 0.0061
Echinococcus granulosus lysosomal alpha glucosidase 0.033 0.1037 0.1033
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0146 0.0909
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0118 0.0225
Loa Loa (eye worm) hypothetical protein 0.0082 0.0185 0.0359
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1037 0.1033
Trichomonas vaginalis glucosylceramidase, putative 0.1305 0.4393 1
Brugia malayi Isocitrate dehydrogenase 0.0129 0.0348 0.0683
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0118 0.0225
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0064 0.0066
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0025 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0529 0.0529
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0118 0.0225
Mycobacterium tuberculosis Conserved protein 0.007 0.0146 0.0909
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0118 0.0118
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0146 0.0254
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0021 0.0045
Echinococcus granulosus muscleblind protein 0.0438 0.1409 0.1405
Loa Loa (eye worm) hypothetical protein 0.0039 0.0037 0.0064
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0851 0.283 1
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0851 0.283 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0057 0.01 0.0095
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0057 0.01 0.01
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0771 0.0771
Brugia malayi Muscleblind-like protein 0.0438 0.1409 0.2789
Schistosoma mansoni hypothetical protein 0.024 0.073 0.073
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0155 0.0275
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.024 0.073 0.1442
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0064 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0118 0.0225
Brugia malayi nuclear hormone receptor 0.0062 0.0118 0.0225
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.1493 0.5039 1
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.076 0.2517 0.4991
Toxoplasma gondii ABC1 family protein 0.007 0.0146 0.0396
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0064 0.0066
Brugia malayi beta-lactamase 0.007 0.0146 0.0281
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0146 0.0442
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0118 0.0225
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0035 0.0092
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0118 0.0118
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0118 0.0113
Mycobacterium leprae conserved hypothetical protein 0.007 0.0146 1
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0043 0.0039
Schistosoma mansoni zinc finger protein 0.0051 0.0079 0.0079
Onchocerca volvulus 0.0046 0.0062 0.0201
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0129 0.0348 0.1164
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0118 0.0225
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0118 0.0118
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0556 0.1814 0.6385
Echinococcus granulosus mixed lineage leukemia protein mll 0.0051 0.0079 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0529 0.0525
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0132 0.0357 0.0353
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1037 0.1033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0118 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0118 0.0225
Schistosoma mansoni smad1 5 8 and 0.0041 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Giardia lamblia DNA repair protein RAD52 0.072 0.2382 0.8397
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0529 0.0529
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0118 0.0225
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.0034
Leishmania major hypothetical protein, conserved 0.007 0.0146 0.0484
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0039 0.0037 0.0032
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0146 0.0909
Echinococcus multilocularis dnaJ subfamily B 0.2935 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0035 0.0048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.024 0.073 0.0726
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0146 0.0909
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0118 0.0225
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0035 0.0139
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0146 0.0484
Brugia malayi Smad1 0.0041 0.0043 0.0078
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0116 0.0112
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1305 0.4393 0.8717
Brugia malayi steroid hormone receptor 0.0062 0.0118 0.0225
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0043 0.0078
Schistosoma mansoni hypothetical protein 0.0035 0.0024 0.0024
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0035 0.0147
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0181 0.0527 0.1039
Loa Loa (eye worm) hypothetical protein 0.007 0.0146 0.0281
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.017 0.0328
Brugia malayi CXXC zinc finger family protein 0.0206 0.0612 0.1207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0118 0.0225
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0155 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0138 0.0379 0.0789
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0295 0.0918 0.6284
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.0079 0.0079
Brugia malayi beta-lactamase family protein 0.007 0.0146 0.0281
Loa Loa (eye worm) hypothetical protein 0.0086 0.0198 0.0384
Onchocerca volvulus 0.0062 0.0118 0.0398
Schistosoma mansoni nuclear receptor 0.0029 0.0004 0.0004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0118 0.0398
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0016 0.0024
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0118 0.0225
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0118 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.017 0.017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0035 0.0031
Onchocerca volvulus Huntingtin homolog 0.0244 0.0742 0.2592
Schistosoma mansoni coup transcription factor 0.0062 0.0118 0.0118
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0851 0.283 1
Brugia malayi beta-NAC-like protein 0.0138 0.0379 0.0744
Toxoplasma gondii isocitrate dehydrogenase 0.0129 0.0348 0.1121
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0118 0.0113
Brugia malayi MH2 domain containing protein 0.0041 0.0043 0.0078
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0129 0.0348 0.0344
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0155 0.0517
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.072 0.2382 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0146 0.0281
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0118 0.0225
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.0014 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0138 0.0379 0.0789
Loa Loa (eye worm) hypothetical protein 0.007 0.0146 0.0281
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0004 0.0004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0129 0.0348 0.1203
Entamoeba histolytica hypothetical protein 0.0035 0.0024 0.01
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0118 0.0225
Brugia malayi RNA binding protein 0.0252 0.0771 0.1522
Brugia malayi MH1 domain containing protein 0.0041 0.0043 0.0078
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1305 0.4393 0.8717
Schistosoma mansoni nuclear receptor 0.0029 0.0004 0.0004
Brugia malayi N-terminal motif family protein 0.0181 0.0527 0.1039
Schistosoma mansoni smad 0.0041 0.0043 0.0043
Brugia malayi hypothetical protein 0.03 0.0935 0.1849
Brugia malayi F/Y-rich N-terminus family protein 0.0067 0.0133 0.0255
Loa Loa (eye worm) beta-lactamase 0.007 0.0146 0.0281
Brugia malayi MH2 domain containing protein 0.0041 0.0043 0.0078
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0062 0.0258
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0556 0.1814 0.6367
Onchocerca volvulus 0.0086 0.0198 0.0679
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0004 0.0004
Echinococcus granulosus smad 0.0041 0.0043 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0118 0.0225
Echinococcus multilocularis cpg binding protein 0.0222 0.0666 0.0662
Entamoeba histolytica hypothetical protein 0.0035 0.0024 0.01
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0118 0.0225
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0851 0.283 0.6412
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0039 0.0037 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0062 0.0143
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0129 0.0348 0.1231
Schistosoma mansoni ap endonuclease 0.0038 0.0035 0.0035
Brugia malayi beta-lactamase family protein 0.007 0.0146 0.0281
Plasmodium vivax basic transcription factor 3b, putative 0.0138 0.0379 0.1272
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0198 0.0198
Echinococcus granulosus microtubule associated protein 2 0.2259 0.7673 0.7672
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Brugia malayi Glycosyl hydrolases family 31 protein 0.033 0.1037 0.2052
Trypanosoma cruzi transcription factor btf3, putative 0.0138 0.0379 0.1311
Echinococcus granulosus lysine specific demethylase 5A 0.0077 0.017 0.0165
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0064 0.0122 0.0118
Echinococcus multilocularis muscleblind protein 1 0.0438 0.1409 0.1405
Trypanosoma cruzi transcription factor btf3, putative 0.0138 0.0379 0.1311
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.0142 0.0393 0.0772
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0062 0.0324
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0118 0.0118
Mycobacterium tuberculosis Possible penicillin-binding protein 0.045 0.1453 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0118 0.0113
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0205 0.0608 0.2554
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0851 0.283 0.6412
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0198 0.0193
Leishmania major basic transcription factor 3a, putative 0.0138 0.0379 0.1311
Brugia malayi hypothetical protein 0.1493 0.5039 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.076 0.2517 0.4991
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0118 0.0225
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0016 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0902 0.3008 0.6821
Brugia malayi hypothetical protein 0.0244 0.0742 0.1464
Schistosoma mansoni cpg binding protein 0.0222 0.0666 0.0666
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0043 0.0039
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0851 0.283 0.5611
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 1
Echinococcus granulosus cpg binding protein 0.0222 0.0666 0.0662
Loa Loa (eye worm) hypothetical protein 0.03 0.0935 0.1849
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0118 0.0118
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0118 0.0398
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0016 0.0012
Onchocerca volvulus 0.007 0.0146 0.0497
Loa Loa (eye worm) hypothetical protein 0.007 0.0146 0.0281
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0146 0.0909
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0062 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0062 0.0114
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0064 0.0122 0.0118
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0035 0.0092
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0057 0.01 0.0095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0529 0.0529
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0062 0.0143
Brugia malayi jmjC domain containing protein 0.0077 0.017 0.0328
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0118 0.0113
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0064 0.0066
Schistosoma mansoni alpha-glucosidase 0.0284 0.0879 0.0879
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0021 0.0017
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0016 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0155 0.0275
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0118 0.0113
Brugia malayi Glycosyl hydrolases family 31 protein 0.0073 0.0155 0.0299
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0062 0.0186
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.0014 0.0009
Schistosoma mansoni zinc finger protein 0.0029 0.0004 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0771 0.0771
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0155 0.0275
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0155 0.065
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0043 0.0039
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0129 0.0348 0.1203
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0132 0.0357 0.0353
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0146 0.0442
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0851 0.283 1
Entamoeba histolytica hypothetical protein 0.0205 0.0608 0.2554
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0118 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Loa Loa (eye worm) latrophilin receptor protein 2 0.024 0.073 0.1442
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0035 0.0024 0.01
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.024 0.073 0.0726
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.024 0.073 0.0726
Trichomonas vaginalis conserved hypothetical protein 0.0138 0.0379 0.0789
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0527 0.1839
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0051 0.0079 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0146 0.0141
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0062 0.0143
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0198 0.0384
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0016 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0529 0.0525
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0016 0.0024
Schistosoma mansoni survival motor neuron protein 0.0305 0.0951 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.1305 0.4393 1
Loa Loa (eye worm) RNA binding protein 0.0252 0.0771 0.1522
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0016 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0146 0.0254
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0146 0.0281
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.076 0.2517 0.4991
Schistosoma mansoni cpg binding protein 0.0206 0.0612 0.0612
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 0.283
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0016 0.0012
Echinococcus multilocularis muscleblind protein 0.0438 0.1409 0.1405
Echinococcus granulosus GPCR family 2 0.024 0.073 0.0726
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0129 0.0348 0.0344
Onchocerca volvulus Glucosylceramidase homolog 0.0856 0.2849 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0062 0.0143
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0118 0.0398
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.024 0.073 0.0726
Brugia malayi hypothetical protein 0.0033 0.0016 0.0024
Echinococcus multilocularis Smad4 0.0041 0.0043 0.0039
Echinococcus multilocularis GPCR, family 2 0.024 0.073 0.0726
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0118 0.0113
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0062 0.0186
Mycobacterium ulcerans hypothetical protein 0.007 0.0146 0.0442
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0062 0.0186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0064 0.0066
Loa Loa (eye worm) transcription factor SMAD2 0.0599 0.1963 0.3889
Schistosoma mansoni transcription factor btf3 0.0138 0.0379 0.0379
Toxoplasma gondii NAC domain-containing protein 0.0138 0.0379 0.123
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0129 0.0348 0.2318
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0155 0.0275
Loa Loa (eye worm) hypothetical protein 0.0438 0.1409 0.2789
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0062 0.0324
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0118 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.1305 0.4393 1
Echinococcus multilocularis geminin 0.1899 0.6436 0.6434
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0118 0.0113
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.0079 0.0075
Trichomonas vaginalis esterase, putative 0.007 0.0146 0.0254
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0155 0.0517
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0155 0.065
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0043 0.0078
Echinococcus multilocularis smad 0.0041 0.0043 0.0039
Schistosoma mansoni cpg binding protein 0.0222 0.0666 0.0666
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0198 0.0193
Echinococcus granulosus transcription factor btf3 0.0138 0.0379 0.0375
Brugia malayi hypothetical protein 0.0033 0.0016 0.0024
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0021 0.0017
Schistosoma mansoni hypothetical protein 0.024 0.073 0.073
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0851 0.283 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0035 0.0092
Mycobacterium tuberculosis Conserved protein 0.007 0.0146 0.0909
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0035 0.0031
Brugia malayi ecdysteroid receptor 0.0062 0.0118 0.0225
Mycobacterium leprae Probable lipase LipE 0.007 0.0146 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0225
Plasmodium vivax hypothetical protein, conserved 0.007 0.0146 0.0442
Onchocerca volvulus 0.03 0.0935 0.3273
Loa Loa (eye worm) hypothetical protein 0.024 0.073 0.1442
Loa Loa (eye worm) hypothetical protein 0.0033 0.0016 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0129 0.0348 0.0344
Schistosoma mansoni alpha glucosidase 0.0073 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.0034
Schistosoma mansoni microtubule-associated protein tau 0.2259 0.7673 0.7673
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0129 0.0348 0.0344
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.017 0.017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0064 0.0066
Brugia malayi nuclear receptor NHR-88 0.0062 0.0118 0.0225
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0146 0.0254
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0043 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0062 0.0114
Loa Loa (eye worm) TAR-binding protein 0.0252 0.0771 0.1522
Plasmodium falciparum basic transcription factor 3b, putative 0.0138 0.0379 0.1339
Schistosoma mansoni hypothetical protein 0.0031 0.0009 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0118 0.0225
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0064 0.0066
Mycobacterium ulcerans lipase LipD 0.007 0.0146 0.0442
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0118 0.0225
Entamoeba histolytica hypothetical protein 0.0138 0.0379 0.159
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0146 0.0909
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0046 0.0083
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0129 0.0348 0.1203
Brugia malayi Bromodomain containing protein 0.0077 0.0168 0.0326
Brugia malayi TAR-binding protein 0.0252 0.0771 0.1522
Schistosoma mansoni hypothetical protein 0.024 0.073 0.073
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2414 0.8207 0.8207
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0064 0.0066
Onchocerca volvulus 0.0206 0.0612 0.2136
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Loa Loa (eye worm) isocitrate dehydrogenase 0.0129 0.0348 0.0683
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0024 0.002
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0771 0.0771
Onchocerca volvulus Huntingtin homolog 0.0244 0.0742 0.2592
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0118 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0118 0.0225
Loa Loa (eye worm) MH2 domain-containing protein 0.0599 0.1963 0.3889
Schistosoma mansoni Smad4 0.0041 0.0043 0.0043
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0118 0.0113
Schistosoma mansoni hypothetical protein 0.0519 0.169 0.169
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0035 0.0124
Loa Loa (eye worm) CXXC zinc finger family protein 0.0206 0.0612 0.1207
Schistosoma mansoni hypothetical protein 0.1899 0.6436 0.6436
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0062 0.0143
Trichomonas vaginalis glucosylceramidase, putative 0.1305 0.4393 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0146 0.0281
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0118 0.0225
Schistosoma mansoni alpha-glucosidase 0.0284 0.0879 0.0879
Loa Loa (eye worm) Smad1 0.0041 0.0043 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0856 0.2849 0.6457
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.0079 0.0075
Echinococcus granulosus Smad4 0.0041 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.0077 0.0169 0.0327
Echinococcus granulosus survival motor neuron protein 1 0.1493 0.5039 0.5037
Trichomonas vaginalis sucrase-isomaltase, putative 0.0073 0.0155 0.0275
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0155 0.0275
Trichomonas vaginalis maltase-glucoamylase, putative 0.0073 0.0155 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0064 0.0066
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0004 0.0004
Schistosoma mansoni bromodomain containing protein 0.0139 0.0382 0.0382
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0771 0.0771
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0152 0.0148
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0155 0.0275
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0529 0.0525
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0529 0.0525
Echinococcus multilocularis neutral alpha glucosidase AB 0.0073 0.0155 0.0151
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0146 0.0146
Trichomonas vaginalis glucosylceramidase, putative 0.1305 0.4393 1
Toxoplasma gondii isocitrate dehydrogenase 0.0129 0.0348 0.1121
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0021 0.0076
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.0034
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0033 0.0016 0.0024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.2935 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0035 0.0092
Echinococcus granulosus tar DNA binding protein 0.0252 0.0771 0.0767
Brugia malayi hypothetical protein 0.0035 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0244 0.0742 0.1464

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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