Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0355 | 1 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0355 | 1 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0355 | 1 | 1 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0355 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.019 | 0.0137 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0014 | 0.019 | 0.019 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.0099 | 0.0099 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0662 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.1174 | 0.1003 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0822 | 0.0772 |
Loa Loa (eye worm) | oxidoreductase | 0.0014 | 0.019 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0345 |
Onchocerca volvulus | 0.0014 | 0.019 | 0.0093 | |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0021 | 0.0397 | 0.0301 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0169 | 0.4643 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0662 | 0.0611 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.0099 | 0.0099 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.1174 | 0.1129 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.1174 | 0.1003 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0765 | 0.064 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.019 | 0.0058 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.1174 | 0.1055 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0021 | 0.0397 | 0.0301 |
Mycobacterium ulcerans | thymidylate synthase | 0.0355 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0822 | 0.0772 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.1174 | 0.1003 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.019 | 0.0058 |
Toxoplasma gondii | propionate-CoA ligase | 0.0014 | 0.019 | 0.0093 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.0397 |
Brugia malayi | hypothetical protein | 0.0169 | 0.4643 | 0.4616 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1724 | 0.1724 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0397 | 0.0267 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.1724 | 0.1682 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.1174 | 0.1055 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0633 | 0.0583 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0021 | 0.0397 | 0.0397 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0397 | 0.0301 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.1174 | 0.1129 |
Brugia malayi | CHD4 protein | 0.0013 | 0.0149 | 0.0099 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0014 | 0.019 | 0.0058 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.0301 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0012 | 0.0118 | 0.0118 |
Onchocerca volvulus | 0.0031 | 0.0662 | 0.0569 | |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1174 | 0.1126 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0013 | 0.0149 | 0.0096 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0014 | 0.019 | 0.019 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.0099 | 0.0099 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0397 | 0.0348 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0013 | 0.0149 | 0.0149 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0015 | 0.0206 | 0.0236 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.1724 | 0.1679 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.1724 | 0.1679 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1321 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1724 | 0.1724 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1321 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0355 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0067 | 0.172 | 0.3568 |
Mycobacterium ulcerans | dehydrogenase | 0.0021 | 0.0397 | 0.0211 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1371 |
Brugia malayi | SWIRM domain containing protein | 0.0021 | 0.0397 | 0.0348 |
Echinococcus multilocularis | thymidylate synthase | 0.0355 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0868 | 0.0819 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.1724 | 0.1724 |
Echinococcus granulosus | thymidylate synthase | 0.0355 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.0067 | 0.172 | 0.172 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.1174 | 0.1003 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0868 | 0.0822 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0054 | 0.0054 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0021 | 0.0397 | 0.0301 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0303 | 0.8521 | 0.8492 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0345 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.1174 | 0.1003 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0099 | 0.0049 |
Onchocerca volvulus | 0.0355 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0345 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0021 | 0.0397 | 0.0397 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0355 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.019 | 0.0141 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.019 | 0.0202 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0011 | 0.0099 | 0.0049 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.1174 | 0.1003 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Brugia malayi | Heterochromatin protein 1 | 0.0067 | 0.172 | 0.1678 |
Echinococcus multilocularis | chromobox protein 1 | 0.0067 | 0.172 | 0.172 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.1174 | 0.1003 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0014 | 0.019 | 0.0058 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.1174 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0169 | 0.4643 | 0.4539 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0551 | 0.0995 |
Echinococcus granulosus | chromobox protein 1 | 0.0067 | 0.172 | 0.172 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0014 | 0.019 | 0.0058 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.095 | 0.086 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.1174 | 0.1003 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1174 | 0.1126 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1486 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0054 | 0.0054 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.0099 | 0.0049 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1401 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0014 | 0.019 | 0.0093 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0014 | 0.019 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Echinococcus multilocularis | chromobox protein 1 | 0.0067 | 0.172 | 0.172 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0021 | 0.0397 | 0.0397 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0822 | 0.0698 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0014 | 0.019 | 0.0852 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.1174 | 0.1129 |
Mycobacterium ulcerans | monoamine oxidase | 0.0021 | 0.0397 | 0.0211 |
Brugia malayi | Valyl-tRNA synthetase | 0.0011 | 0.0099 | 0.0049 |
Loa Loa (eye worm) | thymidylate synthase | 0.0355 | 1 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Onchocerca volvulus | 0.0012 | 0.0118 | 0.0019 | |
Echinococcus granulosus | chromobox protein 2 | 0.0011 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0345 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.0099 | 0.0099 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0023 | 0.045 | 0.0355 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0355 | 1 | 1 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0014 | 0.019 | 0.0093 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.145 | 0.1365 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.019 | 0.0141 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0014 | 0.019 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.019 | 0.0137 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0021 | 0.0397 | 0.0211 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.019 | 0.0141 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0014 | 0.019 | 0.0058 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1724 | 0.1724 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0013 | 0.0149 | 0.0149 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0036 | 0.0822 | 0.0644 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0868 | 0.1693 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0014 | 0.019 | 0.0093 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1486 | 0.1486 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0021 | 0.0397 | 0.0267 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1486 | 0.1321 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0067 | 0.172 | 0.1675 |
Schistosoma mansoni | amine oxidase | 0.0021 | 0.0397 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0822 | 0.0772 |
Onchocerca volvulus | 0.003 | 0.0633 | 0.054 | |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0021 | 0.0397 | 0.0397 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.019 | 0.0141 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0712 | 0.0712 |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.0099 | 0.0099 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0355 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.095 | 0.1875 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.1174 | 0.1003 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.019 | 0.0058 |
Mycobacterium ulcerans | oxidoreductase | 0.0021 | 0.0397 | 0.0211 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.1724 | 0.1679 |
Schistosoma mansoni | amine oxidase | 0.0021 | 0.0397 | 0.0397 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0021 | 0.0397 | 0.0211 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1486 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0169 | 0.4643 | 0.457 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.1174 | 0.1003 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0282 | 0.7905 | 0.7877 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.019 | 0.0058 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.1174 | 0.1003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0206 | 0.0236 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0765 | 0.064 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.019 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0822 | 0.0772 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.0822 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0822 | 0.0731 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0662 | 0.0615 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.0099 | 0.0099 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0868 | 0.0777 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0551 | 0.0995 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0712 | 0.0712 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Loa Loa (eye worm) | helicase | 0.0011 | 0.0099 | 0.0045 |
Leishmania major | UDP-galactopyranose mutase | 0.0021 | 0.0397 | 0.0211 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.0099 | 0.0099 |
Onchocerca volvulus | 0.0014 | 0.019 | 0.0093 | |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.019 | 0.0202 |
Onchocerca volvulus | 0.0014 | 0.019 | 0.0093 | |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1174 | 0.1126 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.1649 | 0.1649 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.0099 | 0.0099 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0712 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0345 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0822 | 0.0731 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0355 | 1 | 1 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0014 | 0.019 | 0.0058 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.095 | 0.1875 |
Onchocerca volvulus | 0.0048 | 0.1174 | 0.1086 | |
Onchocerca volvulus | 0.0014 | 0.019 | 0.0093 | |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0013 | 0.0149 | 0.0149 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0712 | 0.0712 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0765 | 0.064 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0765 | 0.064 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.1724 | 0.1724 |
Brugia malayi | RNA binding protein | 0.0067 | 0.1724 | 0.1682 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.1174 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0099 | 0.0045 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0014 | 0.019 | 0.0093 |
Echinococcus granulosus | chromobox protein 1 | 0.0067 | 0.172 | 0.172 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0021 | 0.0397 | 0.0301 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.1174 | 1 |
Brugia malayi | SET domain containing protein | 0.0012 | 0.0118 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.019 | 0.0137 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0303 | 0.8521 | 0.8492 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0021 | 0.0397 | 0.0301 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.1174 | 0.1003 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0397 | 0.0301 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0345 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0868 | 0.1693 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0014 | 0.019 | 0.019 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1724 | 0.1724 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1486 | 0.1321 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.1174 | 0.1003 |
Echinococcus multilocularis | 0.0021 | 0.0397 | 0.0397 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0822 | 0.0772 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0191 | 0.0203 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.1724 | 0.1682 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.0099 | 0.0049 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0298 | 0.0439 |
Onchocerca volvulus | 0.0021 | 0.0397 | 0.0301 | |
Brugia malayi | Protein cec-1. | 0.0011 | 0.0099 | 0.0049 |
Trichomonas vaginalis | chromobox protein, putative | 0.0067 | 0.172 | 0.3568 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0021 | 0.0397 | 0.0397 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1486 | 0.1486 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0014 | 0.019 | 0.0141 |
Schistosoma mansoni | chromobox protein | 0.0067 | 0.172 | 0.172 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.019 | 0.0137 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0021 | 0.0397 | 0.0211 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.0099 | 0.0099 |
Echinococcus multilocularis | chromobox protein 2 | 0.0011 | 0.0099 | 0.0099 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0021 | 0.0397 | 0.0348 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.1724 | 0.1724 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.