Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.5806 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.7332 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.4897 | 0.6521 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0851 | 0.0739 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.5806 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.4897 | 0.5987 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0518 | 0.0242 |
Brugia malayi | MAP kinase sur-1 | 0.0055 | 0.5806 | 0.52 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.4897 | 0.6521 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0055 | 0.5806 | 0.6274 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.4897 | 0.5292 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0055 | 0.5806 | 0.782 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3611 | 0.3902 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.7332 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0055 | 0.5806 | 0.782 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.5806 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0055 | 0.5806 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.5806 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.7956 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0518 | 0.0559 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0055 | 0.5806 | 0.782 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.3599 | 0.2673 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0055 | 0.5806 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0851 | 0.0679 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.5806 | 0.718 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0851 | 0.0739 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.4897 | 0.4159 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.4897 | 0.6521 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0055 | 0.5806 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.4897 | 0.5987 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0055 | 0.5806 | 0.782 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0055 | 0.5806 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.9254 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0055 | 0.5806 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3186 | 0.4076 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.4897 | 0.6521 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3186 | 0.4076 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4024 | 0.4348 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.4897 | 0.5987 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0055 | 0.5806 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.4357 | 0.4709 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0055 | 0.5806 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0055 | 0.5806 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0055 | 0.5806 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0055 | 0.5806 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.