Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.4794 | 0.4193 |
Schistosoma mansoni | 6-phosphofructokinase | 0.011 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.011 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.426 | 0.4005 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.1036 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0425 | 0.0425 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1857 | 0.1495 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.4794 | 0.4563 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.2361 | 0.2361 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.426 | 0.4005 |
Entamoeba histolytica | phosphofructokinase, putative | 0.011 | 1 | 0.5 |
Leishmania major | ATP-dependent phosphofructokinase | 0.011 | 1 | 0.5 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.4794 | 0.3607 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.011 | 1 | 0.5 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.4794 | 0.3607 |
Echinococcus granulosus | 6 phosphofructokinase | 0.011 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1857 | 0.1495 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.011 | 1 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.011 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.011 | 1 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.426 | 0.4005 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1857 | 0.1495 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.14 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1036 | 0.1036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.426 | 0.4005 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.011 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0064 | 0.426 | 0.4005 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.011 | 1 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1857 | 0.1495 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.426 | 0.2951 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.2361 | 0.2022 |
Brugia malayi | 6-phosphofructokinase | 0.011 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.2361 | 0.2022 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.426 | 0.4005 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.011 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.426 | 0.426 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.4794 | 0.4563 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.4794 | 0.3607 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.4794 | 0.4563 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.011 | 1 | 0.5 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.011 | 1 | 0.5 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.1036 | 0.7399 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.426 | 0.2951 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.4794 | 0.4794 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.426 | 0.4005 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.426 | 0.4005 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.426 | 0.426 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.011 | 1 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.011 | 1 | 0.5 |
Loa Loa (eye worm) | phosphofructokinase | 0.011 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.14 | 0.0406 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1857 | 0.1857 |
Brugia malayi | 6-phosphofructokinase | 0.011 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.426 | 0.426 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.14 | 0.0406 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.4794 | 0.4193 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.4794 | 0.3607 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.011 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2361 | 0.2361 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.