Detailed information for compound 765072

Basic information

Technical information
  • TDR Targets ID: 765072
  • Name: 1-(4-fluorophenyl)-2-pyridin-2-yl-1H-chromeno [2,3-c]pyrrole-3,9-dione
  • MW: 372.349 | Formula: C22H13FN2O3
  • H donors: 0 H acceptors: 3 LogP: 3.41 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C1N(c2ccccn2)C(=O)c2c1c(=O)c1c(o2)cccc1
  • InChi: 1S/C22H13FN2O3/c23-14-10-8-13(9-11-14)19-18-20(26)15-5-1-2-6-16(15)28-21(18)22(27)25(19)17-7-3-4-12-24-17/h1-12,19H
  • InChiKey: DRVJBBKZOYDNGA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-fluorophenyl)-2-(2-pyridyl)-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(4-fluorophenyl)-2-(2-pyridyl)-1H-chromeno[2,3-c]pyrrole-3,9-quinone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.003 0.2097
Echinococcus multilocularis carbonic anhydrase 0.011 0.0088 0.0087
Echinococcus multilocularis mothers against decapentaplegic 6 0.0042 0.0025 0.0023
Echinococcus multilocularis mothers against decapentaplegic 5 0.0093 0.0073 0.0071
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0026 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0026 0.0025
Schistosoma mansoni lamin 0.0084 0.0064 0.0063
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0006 0.0216
Mycobacterium ulcerans pyruvate kinase 0.0066 0.0047 0.337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.002 0.0795
Trichomonas vaginalis ferritin, putative 0.0018 0.0003 0.0095
Trichomonas vaginalis ran, putative 0.0021 0.0005 0.0209
Brugia malayi Pre-SET motif family protein 0.0203 0.0175 0.0173
Echinococcus granulosus GPCR family 2 0.0298 0.0263 0.0262
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.003 0.2097
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.025 0.8604
Loa Loa (eye worm) hypothetical protein 0.0298 0.0263 0.0262
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0021 0.0762
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0093 0.3459
Loa Loa (eye worm) hypothetical protein 0.0142 0.0118 0.0117
Plasmodium falciparum importin beta, putative 0.0028 0.0012 0.1253
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0017 0.0572
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0042 0.0025 0.002
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0021 0.0005 0.0381
Echinococcus granulosus pyruvate kinase 0.0066 0.0047 0.0046
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0017 0.1833
Echinococcus multilocularis Smad4 0.0093 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0017 0.0625
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0083 0.3047
Brugia malayi Pyruvate kinase, M2 isozyme 0.0066 0.0047 0.0046
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.0083 0.8075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0026 0.0907
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0148 0.5926
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0005 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0048 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0191 0.0164 0.0163
Echinococcus granulosus pyruvate kinase 0.0034 0.0017 0.0016
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0047 0.1506
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0012 0.001
Echinococcus granulosus pyruvate kinase 0.0066 0.0047 0.0046
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0191 0.0164 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.003 0.1214
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0203 0.0175 0.6476
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Onchocerca volvulus 0.0084 0.0064 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0021
Brugia malayi MH2 domain containing protein 0.0093 0.0073 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0334 0.0297 0.0295
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0026 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0026 0.0025
Schistosoma mansoni apoferritin-2 0.0018 0.0003 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0005 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0015 0.1544
Echinococcus multilocularis carbonic anhydrase II 0.0203 0.0175 0.0174
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0015 0.1643
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Echinococcus granulosus mothers against decapentaplegic 5 0.0093 0.0073 0.0071
Schistosoma mansoni lamin 0.0084 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0005 0.0004
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0015 0.1326
Leishmania major importin beta-1 subunit, putative 0.0023 0.0007 0.0274
Schistosoma mansoni hypothetical protein 0.0326 0.029 0.0288
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0942 0.0863 0.0862
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.003 0.2097
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0093 0.3423
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0017 0.0015
Brugia malayi MH2 domain containing protein 0.0042 0.0025 0.0023
Echinococcus granulosus carbonic anhydrase 0.011 0.0088 0.0087
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.0029
Echinococcus granulosus mothers against decapentaplegic 6 0.0042 0.0025 0.0023
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.003 0.0028
Trypanosoma cruzi target of rapamycin kinase 3 0.0053 0.0036 0.1274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0024 0.0959
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0025 0.0023
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.002 0.0015
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0021 0.002
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.003 0.1127
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0334 0.0297 0.0295
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0203 0.0175 0.0174
Brugia malayi RNA, U transporter 1 0.0081 0.0061 0.006
Echinococcus granulosus importin subunit beta 1 0.0028 0.0012 0.0011
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.025 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.027 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0066 0.0047 0.3422
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0005 0.0003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0298 0.0263 0.0262
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Brugia malayi hypothetical protein 0.0067 0.0049 0.0047
Echinococcus granulosus neuropeptide s receptor 0.0499 0.0451 0.0449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Schistosoma mansoni smad1 5 8 and 0.0093 0.0073 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0022 0.0879
Chlamydia trachomatis pyruvate kinase 0.0066 0.0047 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0026 0.0025
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0034 0.0032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0298 0.0263 0.0262
Brugia malayi steroid hormone receptor 0.0043 0.0026 0.0025
Onchocerca volvulus 0.004 0.0023 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0203 0.0175 0.6476
Mycobacterium ulcerans hypothetical protein 0.0161 0.0135 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0005 0.0003
Loa Loa (eye worm) carbonic anhydrase 3 0.0203 0.0175 0.0174
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0103 0.7558
Schistosoma mansoni aryl hydrocarbon receptor 0.0042 0.0025 0.0024
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0005 0.0003
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni sodium-bile acid cotransporter related 0.436 0.4047 0.4046
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0083 0.9401
Trypanosoma brucei pyruvate kinase 1 0.0066 0.0047 0.1708
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.003 0.2159
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0029 0.0027
Echinococcus granulosus muscleblind protein 0.0155 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0002
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.025 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0093 0.0073 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0334 0.0297 0.0295
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0006 0.0161
Schistosoma mansoni smad1 5 8 and 0.0093 0.0073 0.0071
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0026 0.0907
Echinococcus granulosus smad 0.0093 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.0155 0.013 0.0129
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0004
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0018 0.0016
Brugia malayi nuclear receptor RXR 0.002 0.0005 0.0003
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0005 0.0449
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0093 0.6831
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0005 0.0385
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0047 0.0042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0021 0.071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0005 0.0003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.012 0.4457
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0188 0.0161 0.0159
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.003 0.2097
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0021 0.062
Schistosoma mansoni survival motor neuron protein 0.0052 0.0035 0.0033
Brugia malayi Heterochromatin protein 1 0.0061 0.0042 0.0041
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0019 0.125
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0005 0.0003
Schistosoma mansoni cpg binding protein 0.0033 0.0017 0.0015
Echinococcus multilocularis serine protein kinase ATM 0.0034 0.0017 0.0016
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Toxoplasma gondii hypothetical protein 0.0049 0.0032 0.2983
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0022 0.1984
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0334 0.0297 0.0295
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0021 0.071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0026 0.0025
Trypanosoma brucei carbonic anhydrase-like protein 0.0203 0.0175 0.6476
Schistosoma mansoni sodium-bile acid cotransporter related 1.0752 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Brugia malayi hypothetical protein 0.0023 0.0007 0.0006
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0053 0.0036 0.1274
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0014 0.0012
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0225 0.0224
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Schistosoma mansoni hypothetical protein 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0155 0.013 0.0129
Schistosoma mansoni apoferritin-2 0.0018 0.0003 0.0001
Echinococcus granulosus sodium bile acid cotransporter 1.0752 1 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0147 0.0145
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0026 0.0025
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0088 0.0087
Schistosoma mansoni ferritin light chain 0.0018 0.0003 0.0001
Brugia malayi Cytochrome P450 family protein 0.003 0.0014 0.0012
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0062 0.0044 0.1631
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0017 0.195
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0093 0.3139
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Schistosoma mansoni Smad4 0.0042 0.0025 0.0023
Trypanosoma brucei glucosidase, putative 0.0038 0.0022 0.0749
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0203 0.0175 0.0174
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0942 0.0863 0.0862
Plasmodium falciparum pyruvate kinase 0.0066 0.0047 0.5272
Schistosoma mansoni zinc finger protein 0.002 0.0005 0.0003
Leishmania major pyruvate kinase 0.0066 0.0047 0.1754
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.003 0.248
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.003 0.2097
Loa Loa (eye worm) hypothetical protein 0.0257 0.0225 0.0224
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0015 0.0404
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0047 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0026 0.0025
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0225 0.0224
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0147 0.0145
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.003 0.248
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Onchocerca volvulus 0.023 0.0201 0.0196
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0017 0.0016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.003 0.0944
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0002 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.012 0.4427
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0103 0.7539
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0018 0.0696
Schistosoma mansoni importin beta-1 0.0028 0.0012 0.0011
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0005 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0103 0.0101
Echinococcus multilocularis ferritin 0.0018 0.0003 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0052 0.0051
Brugia malayi MH1 domain containing protein 0.0051 0.0034 0.0032
Brugia malayi 6-phosphofructokinase 0.0115 0.0093 0.0092
Mycobacterium ulcerans putative regulatory protein 0.0031 0.0015 0.0944
Schistosoma mansoni ran 0.0021 0.0005 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0037 0.002 0.0792
Echinococcus multilocularis carbonic anhydrase 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni cellular tumor antigen P53 0.0203 0.0175 0.0174
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0062 0.0044 0.1418
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0175 0.0173
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.003 0.2097
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0019 0.0003 0.0069
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Brugia malayi N-terminal motif family protein 0.0191 0.0164 0.0163
Echinococcus multilocularis lamin 0.0084 0.0064 0.0063
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0572
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0021 0.002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0021 0.0019
Toxoplasma gondii hypothetical protein 0.011 0.0088 0.8589
Onchocerca volvulus 0.0052 0.0035 0.003
Echinococcus multilocularis lamin dm0 0.0084 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 1.0752 1 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0088 0.0087
Schistosoma mansoni ferritin light chain 0.0018 0.0003 0.0001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0026 0.0025
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0026 0.0025
Brugia malayi MH2 domain containing protein 0.1366 0.1258 0.1257
Brugia malayi hypothetical protein 0.0122 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Echinococcus multilocularis muscleblind protein 1 0.0155 0.013 0.0129
Echinococcus multilocularis pyruvate kinase 0.0034 0.0017 0.0016
Schistosoma mansoni hypothetical protein 0.047 0.0424 0.0423
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0062 0.0044 0.0042
Brugia malayi hypoxia-induced factor 1 0.0131 0.0108 0.0106
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0088 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0061 0.0042 0.169
Brugia malayi hypothetical protein 0.0326 0.029 0.0288
Echinococcus multilocularis carbonic anhydrase 0.011 0.0088 0.0087
Schistosoma mansoni alpha-glucosidase 0.0149 0.0124 0.0123
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0012 0.0406
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0021
Brugia malayi bHLH-PAS transcription factor 0.0031 0.0015 0.0014
Loa Loa (eye worm) heterochromatin protein 1 0.0061 0.0042 0.0041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0007 0.0288
Brugia malayi nuclear receptor RXR 0.0023 0.0007 0.0006
Echinococcus multilocularis microtubule associated protein 2 0.0749 0.0684 0.0682
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0088 0.0087
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0062 0.0044 0.1584
Brugia malayi AMP-binding enzyme family protein 0.0048 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus carbonic anhydrase II 0.0203 0.0175 0.0174
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Echinococcus granulosus carbonic anhydrase 0.011 0.0088 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0305 0.027 1
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0047 0.0045
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0334 0.0297 0.0295
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0019 0.0003 0.0002
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Echinococcus granulosus geminin 0.0743 0.0678 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0026 0.0025
Schistosoma mansoni smad1 5 8 and 0.0093 0.0073 0.0071
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0015 0.039
Echinococcus granulosus Smad4 0.0093 0.0073 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0014 0.0012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0045 0.4316
Schistosoma mansoni nuclear hormone receptor 0.002 0.0005 0.0003
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.0221 0.0219
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0026 0.0021
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0028 0.0026
Echinococcus multilocularis musashi 0.0084 0.0064 0.0063
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0093 0.3423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0084 0.0064 0.0063
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.011 0.0088 0.0087
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0103 0.0101
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0017 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0014 0.0012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0022 0.0636
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.002 0.0795
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.003 0.2159
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.001
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0026 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0743 0.0678 0.0677
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0026 0.0025
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.011 0.0088 0.0087
Giardia lamblia Pyruvate kinase 0.0066 0.0047 0.1714
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0018 0.0696
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0047 0.0045
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0021 0.06
Trypanosoma brucei pyruvate kinase 1, putative 0.0066 0.0047 0.1708
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.0083 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0044 0.1754
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Brugia malayi Muscleblind-like protein 0.0155 0.013 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0026 0.0025
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0088 0.0087
Brugia malayi Latrophilin receptor protein 2 0.0298 0.0263 0.0262
Brugia malayi latrophilin 2 splice variant baaae 0.0644 0.0585 0.0584
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0047 0.0042
Brugia malayi RNA binding protein 0.0333 0.0296 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0093 0.3669
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0093 0.0073 0.0071
Brugia malayi phosphofructokinase 0.0115 0.0093 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0023 0.0021
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0007 0.0006
Brugia malayi MH2 domain containing protein 0.0093 0.0073 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0147 0.0145
Brugia malayi hypothetical protein 0.0257 0.0225 0.0224
Schistosoma mansoni nuclear receptor 0.002 0.0005 0.0003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0298 0.0263 0.0262
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0298 0.0263 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0027 0.1086
Onchocerca volvulus 1.0752 1 1
Echinococcus granulosus snurportin 1 0.0304 0.0269 0.0267
Mycobacterium ulcerans hypothetical protein 0.0048 0.003 0.2097
Schistosoma mansoni transcription factor LCR-F1 0.0326 0.029 0.0288
Brugia malayi nuclear hormone receptor 0.002 0.0005 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Onchocerca volvulus 0.0031 0.0015 0.001
Schistosoma mansoni pyruvate kinase 0.0066 0.0047 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0298 0.0263 0.0262
Loa Loa (eye worm) MH1 domain-containing protein 0.0093 0.0073 0.0071
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0022 0.0857
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0269 0.0267
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0334 0.0297 0.0295
Loa Loa (eye worm) hypothetical protein 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0002 0.0078
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0047 0.1679
Onchocerca volvulus 0.01 0.0079 0.0074
Echinococcus multilocularis neuropeptide s receptor 0.0499 0.0451 0.0449
Brugia malayi hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.1366 0.1258 0.1257
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0012 0.1076
Brugia malayi Pyruvate kinase, muscle isozyme 0.0066 0.0047 0.0046
Echinococcus multilocularis mothers against decapentaplegic 2 0.0042 0.0025 0.0023
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0005 0.0145
Loa Loa (eye worm) Smad1 0.0093 0.0073 0.0071
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0026 0.0025
Onchocerca volvulus 0.0203 0.0175 0.0171
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.0029
Echinococcus granulosus tar DNA binding protein 0.0333 0.0296 0.0294
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0047 0.1887
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0044 0.0042
Schistosoma mansoni nuclear receptor 0.002 0.0005 0.0003
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0017 0.0015
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0009 0.0262
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0148 0.5926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0027 0.1086
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0047 0.1887
Plasmodium vivax pyruvate kinase, putative 0.0066 0.0047 0.5607
Echinococcus granulosus pyruvate kinase 0.0034 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0017 0.0686
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0026 0.0025
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0022 0.08
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.003 0.0028
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.0083 0.3047
Echinococcus multilocularis pyruvate kinase 0.0034 0.0017 0.0016
Echinococcus multilocularis GPCR, family 2 0.0298 0.0263 0.0262
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.014 0.0135
Schistosoma mansoni smad 0.0042 0.0025 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.0499 0.0451 0.0449
Brugia malayi RNA recognition motif domain containing protein 0.0333 0.0296 0.0294
Echinococcus granulosus carbonic anhydrase 0.011 0.0088 0.0087
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0007 0.0006
Loa Loa (eye worm) TAR-binding protein 0.0333 0.0296 0.0294
Schistosoma mansoni alpha glucosidase 0.0038 0.0022 0.002
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0007 0.0006
Onchocerca volvulus Huntingtin homolog 0.0122 0.0099 0.0094
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.025 0.8604
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0093 0.0092
Leishmania major GTP-binding protein, putative 0.0021 0.0005 0.02
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0115 0.8456
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.003 0.0944
Loa Loa (eye worm) hypothetical protein 0.0122 0.0099 0.0098
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0021 0.0019
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0001 0.0055
Schistosoma mansoni carbonic anhydrase 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0572
Echinococcus multilocularis snurportin 1 0.0304 0.0269 0.0267
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0103 0.0101
Schistosoma mansoni cpg binding protein 0.0035 0.0018 0.0017
Brugia malayi MH1 domain containing protein 0.0051 0.0034 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0103 0.7539
Brugia malayi PAS domain containing protein 0.0042 0.0025 0.0024
Schistosoma mansoni pyruvate kinase 0.0034 0.0017 0.0016
Echinococcus multilocularis pyruvate kinase 0.0066 0.0047 0.0046
Toxoplasma gondii target of rapamycin (TOR), putative 0.0051 0.0034 0.3165
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0012 0.0406
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0005 0.0003
Schistosoma mansoni fkbp-rapamycin associated protein 0.0019 0.0003 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0147 0.0145
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0005 0.0003
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0021 0.0816
Schistosoma mansoni hypothetical protein 0.0743 0.0678 0.0677
Echinococcus granulosus lamin dm0 0.0084 0.0064 0.0063
Leishmania major carbonic anhydrase-like protein 0.0203 0.0175 0.6496
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0203 0.0175 0.0174
Schistosoma mansoni chromobox protein 0.0061 0.0042 0.0041
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0019 0.1319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Echinococcus granulosus chromobox protein 1 0.0061 0.0042 0.0041
Brugia malayi TAR-binding protein 0.0333 0.0296 0.0294
Schistosoma mansoni hypothetical protein 0.0052 0.0035 0.0033
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.0221 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Leishmania major hypothetical protein, conserved 0.0104 0.0083 0.3085
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.003 0.2097
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0035 0.0033
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0017 0.0015
Brugia malayi 6-phosphofructokinase 0.0115 0.0093 0.0092
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Brugia malayi Importin beta-1 subunit 0.0028 0.0012 0.0011
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0115 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0012 0.0011
Brugia malayi nuclear receptor NHR-88 0.002 0.0005 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.0135 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0066 0.0047 0.0046
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0203 0.0175 0.0174
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0062 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0093 0.0092
Echinococcus multilocularis tar DNA binding protein 0.0333 0.0296 0.0294
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.003 0.1127
Onchocerca volvulus 0.0084 0.0064 0.0059
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0047 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Brugia malayi hypothetical protein 0.0104 0.0083 0.0082
Echinococcus granulosus cpg binding protein 0.0035 0.0018 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0022 0.0749
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.002 0.0795
Echinococcus multilocularis sodium bile acid cotransporter 1.0752 1 1
Brugia malayi MH1 domain containing protein 0.0093 0.0073 0.0071
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0026 0.0025
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.003 0.1127
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0028 0.0026
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0103 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0026 0.0025
Echinococcus multilocularis expressed protein 0.0018 0.0003 0.0001
Brugia malayi Smad1 0.0093 0.0073 0.0071
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0022 0.0857
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0007 0.0288
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0019 0.0003 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0024 0.0022
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0026 0.0025
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.003 0.0944
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0062 0.0044 0.1631
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0047 0.0042
Loa Loa (eye worm) hypothetical protein 0.0203 0.0175 0.0174
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0625
Echinococcus granulosus mothers against decapentaplegic 2 0.0042 0.0025 0.0023
Giardia lamblia Pyruvate kinase 0.0034 0.0017 0.0492
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0021 0.1355
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0326
Echinococcus granulosus lamin 0.0084 0.0064 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0021 0.2332
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Echinococcus multilocularis pyruvate kinase 0.0034 0.0017 0.0016
Brugia malayi hypothetical protein 0.0023 0.0007 0.0006
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0088 0.0087
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0026 0.0025
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0026 0.0025
Echinococcus granulosus ferritin 0.0018 0.0003 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0083 0.3047
Leishmania major pyruvate kinase 0.0066 0.0047 0.1754
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0026 0.0025
Entamoeba histolytica Ran family GTPase 0.0021 0.0005 0.0071
Echinococcus granulosus dnaJ subfamily B 0.047 0.0424 0.0423
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0026 0.0025
Loa Loa (eye worm) DR-78 0.002 0.0005 0.0003
Schistosoma mansoni nuclear hormone receptor 0.002 0.0005 0.0003
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0005 0.0003
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0062 0.0044 0.1418
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0015 0.05
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0115 0.8468
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0026 0.0025
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0093 0.8079
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0026 0.0025
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0015 0.1544
Echinococcus multilocularis chromobox protein 1 0.0061 0.0042 0.0041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0007 0.0288
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0026 0.0025
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0064 0.0063
Brugia malayi conserved hypotetical protein 0.002 0.0005 0.0003
Brugia malayi Nuclear hormone receptor E75 0.002 0.0005 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0022 0.002
Onchocerca volvulus Huntingtin homolog 0.0122 0.0099 0.0094
Schistosoma mansoni alpha-glucosidase 0.0149 0.0124 0.0123
Toxoplasma gondii pyruvate kinase PyK1 0.0066 0.0047 0.4528
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Brugia malayi nuclear receptor NHR-67 0.002 0.0005 0.0003
Onchocerca volvulus 0.0033 0.0017 0.0012
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0103 0.3808
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0026 0.0025
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis dnaJ subfamily B 0.047 0.0424 0.0423
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0026 0.0025
Brugia malayi ecdysone receptor 0.002 0.0005 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0103 0.7539
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0005 0.0145
Echinococcus granulosus chromobox protein 1 0.0061 0.0042 0.0041
Schistosoma mansoni Smad4 0.0093 0.0073 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0026 0.0025
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0062 0.0044 0.1584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0034 0.0017 0.059
Echinococcus multilocularis pyruvate kinase 0.0052 0.0034 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0026 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0022 0.0749
Schistosoma mansoni hypothetical protein 0.0047 0.003 0.0028
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0326 0.029 0.0288
Trichomonas vaginalis chromobox protein, putative 0.0037 0.002 0.0792
Echinococcus granulosus pyruvate kinase 0.0034 0.0017 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0026 0.0025
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0093 0.3139
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0326 0.029 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0572
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0047 0.1679
Loa Loa (eye worm) hypothetical protein 0.0188 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0104 0.0083 0.0082
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0093 0.0073 0.0071
Brugia malayi MH1 domain containing protein 0.0093 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.0644 0.0585 0.0584
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0047 0.1725
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.027 1
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0015 0.1326
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0005 0.0003
Schistosoma mansoni microtubule-associated protein tau 0.0749 0.0684 0.0682
Entamoeba histolytica hypothetical protein 0.0023 0.0007 0.014
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0026 0.0025
Brugia malayi nuclear receptor NHR-88 0.0043 0.0026 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0003 0.0127
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0093 0.6856
Echinococcus granulosus single minded 2 0.0031 0.0015 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.1366 0.1258 0.1257
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0007 0.0006
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0029 0.0886
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Loa Loa (eye worm) hypothetical protein 0.0083 0.0063 0.0061
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0005 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4181 0.388 0.3879
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0093 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Brugia malayi hypothetical protein 0.002 0.0005 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0093 0.0092
Echinococcus multilocularis chromobox protein 1 0.0061 0.0042 0.0041
Loa Loa (eye worm) nuclear factor I 0.0051 0.0034 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0027
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0005 0.0003
Schistosoma mansoni chromobox protein 0.0061 0.0042 0.0041
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Mycobacterium leprae Probable pyruvate kinase PykA 0.0066 0.0047 0.3985
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0021 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0024 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0026 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0326
Trichomonas vaginalis set domain proteins, putative 0.023 0.0201 0.8023
Schistosoma mansoni ap endonuclease 0.0037 0.0021 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0021 0.0816
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0022 0.0636
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0034 0.0017 0.059
Brugia malayi intermediate filament protein 0.0084 0.0064 0.0063
Brugia malayi Calcitonin receptor-like protein seb-1 0.0942 0.0863 0.0862
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0017 0.0015
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0034 0.0018 0.0013
Loa Loa (eye worm) hypoxia-induced factor 1 0.0131 0.0108 0.0106
Brugia malayi chromobox protein homolog 3 0.0034 0.0018 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0334 0.0297 0.0295
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0019 0.1307
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0015 0.059
Schistosoma mansoni hypothetical protein 0.0304 0.0269 0.0267
Schistosoma mansoni sodium-bile acid cotransporter 0.6392 0.5939 0.5939
Brugia malayi Nuclear hormone receptor E75 0.002 0.0005 0.0003
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0019 0.2032
Loa Loa (eye worm) hypothetical protein 0.003 0.0014 0.0012
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0005 0.0145
Loa Loa (eye worm) RNA binding protein 0.0333 0.0296 0.0294
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0333 0.0296 0.0294
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0103 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0026 0.0907
Plasmodium falciparum carbonic anhydrase 0.011 0.0088 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0047 0.1679
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0026 0.0025
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0003 0.0079
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0047 0.0046
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0034 0.0017 0.0016
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0093 0.3139
Brugia malayi ecdysteroid receptor 0.0043 0.0026 0.0025
Echinococcus granulosus intermediate filament protein 0.0084 0.0064 0.0063
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0007 0.0006
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0015 0.1643
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Echinococcus multilocularis transfer RNA-Lys 0.0031 0.0015 0.0014
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0088 0.0087
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0015 0.1326
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.011 0.0088 0.0087
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0026 0.0025
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0047 0.1708
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0005 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Echinococcus granulosus sodium bile acid cotransporter 1.0752 1 1
Schistosoma mansoni ap endonuclease 0.0037 0.0021 0.0019
Schistosoma mansoni cpg binding protein 0.0035 0.0018 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0093 0.0092
Schistosoma mansoni smad 0.0093 0.0073 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0003 0.0002
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0093 0.0092
Schistosoma mansoni ran 0.0021 0.0005 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0022 0.0857
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0093 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0007 0.0006
Schistosoma mansoni single-minded 0.0042 0.0025 0.0024
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0026 0.0025
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0017 0.0015
Onchocerca volvulus 0.0027 0.0011 0.0006
Brugia malayi tailless protein 0.002 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0044 0.1754
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0334 0.0297 0.0295
Schistosoma mansoni hypothetical protein 0.0644 0.0585 0.0584
Echinococcus multilocularis cpg binding protein 0.0035 0.0018 0.0017
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0083 0.9401
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0026 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0035 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0298 0.0263 0.0262
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0011 0.0368
Echinococcus multilocularis smad 0.0093 0.0073 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0007 0.0006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0026 0.0025
Echinococcus multilocularis geminin 0.0743 0.0678 0.0677
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Schistosoma mansoni coup transcription factor 0.0043 0.0026 0.0025
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0062 0.0044 0.1584
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Trichomonas vaginalis chromobox protein, putative 0.0061 0.0042 0.169
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0005 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0014 0.1191
Giardia lamblia GTOR 0.0062 0.0044 0.1578
Brugia malayi CXXC zinc finger family protein 0.0033 0.0017 0.0015
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0019 0.2161
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Loa Loa (eye worm) hypothetical protein 0.0942 0.0863 0.0862
Toxoplasma gondii exonuclease III APE 0.0037 0.0021 0.1883
Brugia malayi hypothetical protein 0.0142 0.0118 0.0117
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.003 0.0014 0.0455
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0005 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0267 0.0235 0.0233
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0026 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0005 0.0004
Echinococcus multilocularis sodium bile acid cotransporter 1.0752 1 1
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0017 0.1574
Schistosoma mansoni Smad4 0.0042 0.0025 0.0023
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0021 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0207
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0047 0.0045
Brugia malayi mothers against decapentaplegic homolog 3 0.0042 0.0025 0.0023
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0009
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0026 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0026 0.0025
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0005 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0334 0.0297 0.0295
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0026 0.0907
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0026 0.0025
Echinococcus multilocularis pyruvate kinase 0.0066 0.0047 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0044 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0003 0.0127
Echinococcus granulosus microtubule associated protein 2 0.0749 0.0684 0.0682
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0021 0.0019
Echinococcus granulosus tumor protein p63 0.139 0.1281 0.1279
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0003 0.0079
Plasmodium vivax importin-beta 2, putative 0.0028 0.0012 0.1333
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0064 0.0063
Echinococcus granulosus serine protein kinase ATM 0.0034 0.0017 0.0016
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0022 0.0857
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0147 0.0145
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0062 0.0044 0.0042
Echinococcus granulosus neuropeptide receptor A26 0.0499 0.0451 0.0449
Onchocerca volvulus 0.0043 0.0026 0.0021
Echinococcus granulosus sodium bile acid cotransporter 1.0752 1 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0047 0.1708
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Plasmodium vivax SET domain protein, putative 0.003 0.0014 0.1474
Toxoplasma gondii FATC domain-containing protein 0.0034 0.0017 0.1563
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.012 0.4427
Schistosoma mansoni intermediate filament proteins 0.0084 0.0064 0.0063
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0022 0.002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0021 0.071
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0062 0.0044 0.1584
Onchocerca volvulus 0.0048 0.003 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0044 0.1754
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0025 0.0023
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0021 1
Leishmania major mitochondrial DNA polymerase beta 0.0305 0.027 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0021 0.1423
Brugia malayi Pre-SET motif family protein 0.003 0.0014 0.0012
Echinococcus granulosus TGF beta signal transducer SmadC 0.0093 0.0073 0.0071
Echinococcus multilocularis sodium bile acid cotransporter 1.0752 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0026 0.0025
Entamoeba histolytica hypothetical protein 0.0034 0.0017 0.0487
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0026 0.0025
Echinococcus granulosus expressed protein 0.0018 0.0003 0.0001
Schistosoma mansoni pyruvate kinase 0.0066 0.0047 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0156 0.6245
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0053 0.0036 0.1322
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0022 0.002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0007 0.0219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0203 0.0175 0.0174
Echinococcus multilocularis tumor protein p63 0.139 0.1281 0.1279
Loa Loa (eye worm) hypothetical protein 0.0122 0.0099 0.0098
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0021 0.2192
Brugia malayi AMP-binding enzyme family protein 0.0048 0.003 0.0029
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0005 0.0477
Brugia malayi nuclear hormone receptor 0.0043 0.0026 0.0025
Echinococcus multilocularis muscleblind protein 0.0155 0.013 0.0129
Brugia malayi follicle stimulating hormone receptor 0.0267 0.0235 0.0233

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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