Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0305 | 0.167 | 0.2048 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0159 | 0.0809 | 0.0899 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0034 | 0.0068 | 0.0078 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0115 | 0.0092 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0028 | 0.0034 | 0.0013 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0081 | 0.0346 | 0.0327 |
Schistosoma mansoni | tar DNA-binding protein | 0.0455 | 0.2556 | 0.3135 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0034 | 0.0068 | 0.0078 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0077 | 0.0006 |
Onchocerca volvulus | 0.0038 | 0.0095 | 0.0072 | |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0308 | 0.0377 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.0678 | 0.0831 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0228 | 0.1217 | 0.1493 |
Brugia malayi | hypothetical protein | 0.018 | 0.0933 | 0.1041 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0048 | 0.0149 | 0.0183 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0023 | 0.0015 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0042 | 0.0034 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0044 | 0.0128 | 0.0159 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0075 | 0.0067 |
Brugia malayi | chromobox protein homolog 3 | 0.0042 | 0.0115 | 0.0105 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0052 | 0.0063 |
Loa Loa (eye worm) | TAR-binding protein | 0.0455 | 0.2556 | 0.2915 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0076 | 0.0315 | 0.0296 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0095 | 0.0108 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0283 | 0.154 | 0.4406 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0308 | 0.0288 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0095 | 0.0073 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0076 | 0.0315 | 0.036 |
Schistosoma mansoni | hypothetical protein | 0.0425 | 0.2378 | 0.2916 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0095 | 0.0083 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0095 | 0.0086 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0044 | 0.0128 | 0.0146 |
Schistosoma mansoni | Smad4 | 0.0034 | 0.0068 | 0.0084 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0622 | 0.3539 | 0.402 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0133 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.1338 | 0.1526 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.018 | 0.0933 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0081 | 0.0345 | 0.0423 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0044 | 0.0128 | 0.012 |
Trypanosoma brucei | ISWI complex protein | 0.008 | 0.0339 | 0.0794 |
Echinococcus multilocularis | zinc finger protein | 0.0102 | 0.047 | 0.0453 |
Schistosoma mansoni | thyroid hormone receptor | 0.0282 | 0.1536 | 0.1884 |
Onchocerca volvulus | 0.0249 | 0.1338 | 0.1318 | |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0044 | 0.0128 | 0.2201 |
Leishmania major | hypothetical protein, conserved | 0.018 | 0.0933 | 0.2582 |
Schistosoma mansoni | tar DNA-binding protein | 0.0455 | 0.2556 | 0.3135 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0095 | 0.0116 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.018 | 0.0933 | 0.8064 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0095 | 0.0086 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0044 | 0.0128 | 0.0159 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0261 | 0.1412 | 0.1406 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0103 | 0.0474 | 0.1199 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.018 | 0.0933 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0455 | 0.2556 | 0.2563 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Loa Loa (eye worm) | nuclear factor I | 0.0042 | 0.0116 | 0.0132 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0023 | 0.0015 |
Brugia malayi | jmjC domain containing protein | 0.0102 | 0.0469 | 0.051 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0308 | 0.03 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0115 | 0.0107 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0048 | 0.0149 | 0.0128 |
Brugia malayi | MH2 domain containing protein | 0.0034 | 0.0068 | 0.0052 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0048 | 0.0149 | 0.017 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0308 | 0.0378 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0044 | 0.0128 | 0.012 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0308 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0116 | 0.0132 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.018 | 0.0933 | 0.2582 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0102 | 0.0469 | 0.0451 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0059 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0022 | 0.0026 |
Echinococcus granulosus | smad | 0.0076 | 0.0315 | 0.0296 |
Brugia malayi | MH1 domain containing protein | 0.0042 | 0.0116 | 0.0107 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.0678 | 0.0831 |
Trichomonas vaginalis | set domain proteins, putative | 0.1716 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0133 | 0.0125 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0197 | 0.103 | 0.1152 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0084 | 0.0365 | 0.0872 |
Echinococcus granulosus | Smad4 | 0.0076 | 0.0315 | 0.0296 |
Brugia malayi | Bromodomain containing protein | 0.0391 | 0.2175 | 0.246 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0095 | 0.0086 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0305 | 0.167 | 0.1666 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0346 | 0.0425 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0216 | 0.1145 | 0.1136 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0308 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.1121 | 0.1278 |
Brugia malayi | MH2 domain containing protein | 0.0076 | 0.0315 | 0.0335 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0245 | 0.1314 | 0.7462 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.2378 | 0.2711 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0059 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0076 | 0.0315 | 0.0296 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0095 | 0.5 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0089 | 0.0393 | 0.0375 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0102 | 0.0469 | 0.0451 |
Schistosoma mansoni | alpha glucosidase | 0.0035 | 0.0077 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.0261 | 0.1412 | 0.1732 |
Schistosoma mansoni | bromodomain containing protein | 0.033 | 0.1814 | 0.2225 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0075 | 0.0067 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.0077 | 0.0088 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0076 | 0.0315 | 0.0296 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0282 | 0.1536 | 0.1531 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0037 | 0.0029 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0077 | 0.0069 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0095 | 0.5 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0077 | 0.0233 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0283 | 0.154 | 0.4406 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0133 | 0.0125 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.0308 | 0.0326 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.018 | 0.0933 | 0.2582 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0076 | 0.0315 | 0.036 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0084 | 0.0365 | 0.0872 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0108 |
Schistosoma mansoni | smad | 0.0076 | 0.0315 | 0.0387 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0308 | 0.0289 |
Brugia malayi | MH1 domain containing protein | 0.0076 | 0.0315 | 0.0335 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0108 |
Loa Loa (eye worm) | RNA binding protein | 0.0455 | 0.2556 | 0.2915 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0197 | 0.103 | 0.1174 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0598 | 0.34 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0308 | 0.0289 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0249 | 0.1338 | 0.1641 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0308 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1048 | 0.1195 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0034 | 0.0068 | 0.0046 |
Brugia malayi | Bromodomain containing protein | 0.0199 | 0.1046 | 0.117 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0108 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0077 | 0.0069 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0043 | 0.0035 |
Onchocerca volvulus | 0.0228 | 0.1217 | 0.1197 | |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0059 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0123 | 0.0102 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0308 | 0.0288 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0076 | 0.0315 | 0.0387 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1403 | 0.8154 | 0.8226 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.1508 | 0.877 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0108 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0077 | 0.0069 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0077 | 0.0062 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.018 | 0.0933 | 0.8064 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0044 | 0.0128 | 0.0159 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0117 | 0.0562 | 0.0689 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0089 | 0.0393 | 0.0482 |
Brugia malayi | jmjC domain containing protein | 0.0048 | 0.0149 | 0.0145 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0044 | 0.0128 | 0.012 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0044 | 0.0128 | 0.2201 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0308 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0022 | 0.0026 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0022 | 0.0028 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0044 | 0.0128 | 0.0107 |
Onchocerca volvulus | 0.0033 | 0.0062 | 0.0039 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0115 | 0.0131 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0095 | 0.0086 |
Giardia lamblia | GTOR | 0.0044 | 0.0128 | 1 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0077 | 0.0069 |
Onchocerca volvulus | 0.0092 | 0.0412 | 0.0391 | |
Loa Loa (eye worm) | bromodomain containing protein | 0.0092 | 0.0412 | 0.0469 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0075 | 0.0067 |
Echinococcus multilocularis | tar DNA binding protein | 0.0455 | 0.2556 | 0.2563 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0107 | 0.0503 | 0.0573 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.118 | 0.1345 |
Echinococcus multilocularis | Smad4 | 0.0076 | 0.0315 | 0.0296 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.0339 | 0.0794 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0077 | 0.0006 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0159 | 0.0809 | 0.0796 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0077 | 0.0069 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0305 | 0.167 | 0.2048 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.0308 | 0.0351 |
Echinococcus multilocularis | GPCR, family 2 | 0.0197 | 0.103 | 0.1019 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0043 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.103 | 0.1263 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.0247 | 0.0281 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0022 | 0.0026 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0308 | 0.0326 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0084 | 0.0365 | 0.0872 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 0.167 | 0.1904 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0123 | 0.0102 |
Echinococcus multilocularis | tumor protein p63 | 0.17 | 0.9908 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0048 | 0.0149 | 0.0183 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0034 | 0.0068 | 0.0046 |
Brugia malayi | Pre-SET motif family protein | 0.0216 | 0.1145 | 0.1283 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0197 | 0.103 | 0.1019 |
Brugia malayi | PHD-finger family protein | 0.013 | 0.0634 | 0.07 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0089 | 0.0393 | 0.0482 |
Brugia malayi | Smad1 | 0.0076 | 0.0315 | 0.0335 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.002 | 0.0022 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0034 | 0.0068 | 0.0046 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0052 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0052 | 0.0063 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0044 | 0.0128 | 0.012 |
Loa Loa (eye worm) | Smad1 | 0.0076 | 0.0315 | 0.036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0455 | 0.2556 | 0.3135 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0022 | 0.0014 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.009 | 0.0069 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0052 | 0.0033 |
Schistosoma mansoni | zinc finger protein | 0.008 | 0.0339 | 0.0416 |
Schistosoma mansoni | smad1 5 8 and | 0.0076 | 0.0315 | 0.0387 |
Schistosoma mansoni | lamin | 0.0026 | 0.0022 | 0.0028 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0425 | 0.2378 | 0.2693 |
Toxoplasma gondii | hypothetical protein | 0.0096 | 0.0438 | 0.3534 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0187 | 0.0973 | 0.0962 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0076 | 0.0315 | 0.0296 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0095 | 0.0116 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0115 | 0.0107 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0077 | 0.0069 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0305 | 0.167 | 0.1666 |
Trypanosoma cruzi | ISWI complex protein | 0.008 | 0.0339 | 0.0794 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0308 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0117 | 0.0562 | 0.0545 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0077 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0339 | 0.0416 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0095 | 0.0083 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1403 | 0.8154 | 0.8226 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0084 | 0.0365 | 0.0872 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0261 | 0.1412 | 0.1406 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0075 | 0.0067 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0308 | 0.03 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0077 | 0.0055 |
Echinococcus multilocularis | peregrin | 0.0043 | 0.0124 | 0.0103 |
Schistosoma mansoni | Smad4 | 0.0034 | 0.0068 | 0.0084 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0044 | 0.0128 | 0.0159 |
Schistosoma mansoni | smad1 5 8 and | 0.0076 | 0.0315 | 0.0387 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0052 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0368 | 0.2043 | 0.233 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 0.0809 | 0.0796 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 0.0809 | 0.0796 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0061 | 0.0053 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0187 | 0.0973 | 0.0962 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.018 | 0.0933 | 0.2582 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.0503 | 0.0617 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0075 | 0.0067 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0034 | 0.0068 | 0.0046 |
Brugia malayi | MH2 domain containing protein | 0.0076 | 0.0315 | 0.0335 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.103 | 0.1263 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0077 | 0.0055 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0077 | 0.0069 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0598 | 0.34 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0095 | 0.0073 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0598 | 0.34 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0077 | 0.0006 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0308 | 1 |
Brugia malayi | RNA binding protein | 0.0455 | 0.2556 | 0.2897 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.103 | 0.1263 |
Echinococcus granulosus | tumor protein p63 | 0.17 | 0.9908 | 1 |
Brugia malayi | MH2 domain containing protein | 0.1111 | 0.6429 | 0.7324 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0108 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0197 | 0.103 | 0.1019 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0598 | 0.34 | 1 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0089 | 0.0393 | 0.0375 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0216 | 0.1145 | 0.1405 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0622 | 0.3539 | 0.4036 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0034 | 0.0068 | 0.0046 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0622 | 0.3539 | 0.402 |
Schistosoma mansoni | smad | 0.0034 | 0.0068 | 0.0084 |
Onchocerca volvulus | 0.0038 | 0.0095 | 0.0072 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0022 | 0.0014 |
Brugia malayi | Pre-SET motif family protein | 0.1508 | 0.877 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0311 | 0.1704 | 0.1701 |
Schistosoma mansoni | thyroid hormone receptor | 0.0282 | 0.1536 | 0.1884 |
Schistosoma mansoni | zinc finger protein | 0.0102 | 0.047 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0052 | 0.0059 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0052 | 0.003 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0034 | 0.0068 | 0.0052 |
Echinococcus granulosus | peregrin | 0.0043 | 0.0124 | 0.0103 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0308 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0076 | 0.0315 | 0.0387 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0311 | 0.1704 | 0.1701 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0197 | 0.103 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0622 | 0.3539 | 0.4036 |
Brugia malayi | MH1 domain containing protein | 0.0042 | 0.0116 | 0.0107 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.0124 | 0.0117 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0095 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0062 | 0.007 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0052 | 0.003 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0044 | 0.0128 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0068 | 0.0078 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0216 | 0.1145 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.0022 | 0.0028 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0315 | 0.1729 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0394 |
Echinococcus granulosus | zinc finger protein | 0.0102 | 0.047 | 0.0453 |
Brugia malayi | TAR-binding protein | 0.0455 | 0.2556 | 0.2897 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0208 | 0.1098 | 0.1088 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0197 | 0.103 | 0.1019 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0283 | 0.154 | 0.4406 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0059 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0095 | 0.0083 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.103 | 0.1263 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0159 | 0.0809 | 0.0922 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0033 | 0.0061 | 0.0089 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0077 | 0.0006 |
Echinococcus multilocularis | smad | 0.0076 | 0.0315 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0183 | 0.0208 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.1111 | 0.6429 | 0.7331 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0095 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.0933 | 0.1064 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0197 | 0.103 | 0.1152 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.1111 | 0.6429 | 0.7331 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1403 | 0.8154 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0108 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0044 | 0.0128 | 0.0107 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0044 | 0.0128 | 0.0159 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0095 | 0.0394 |
Echinococcus granulosus | GPCR family 2 | 0.0197 | 0.103 | 0.1019 |
Brugia malayi | hypothetical protein | 0.0116 | 0.0556 | 0.061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0455 | 0.2556 | 0.3135 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0308 | 0.0289 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0081 | 0.0346 | 0.0327 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0044 | 0.0128 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.103 | 0.1174 |
Brugia malayi | MH1 domain containing protein | 0.0076 | 0.0315 | 0.0335 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.009 | 0.0082 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0117 | 0.0562 | 0.0545 |
Plasmodium vivax | SET domain protein, putative | 0.0216 | 0.1145 | 1 |
Onchocerca volvulus | 0.0038 | 0.0095 | 0.0072 | |
Schistosoma mansoni | Smad4 | 0.0076 | 0.0315 | 0.0387 |
Trypanosoma cruzi | ISWI complex protein | 0.008 | 0.0339 | 0.0794 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0455 | 0.2556 | 0.2897 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0455 | 0.2556 | 0.2915 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0095 | 0.0086 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0023 | 0.0015 |
Schistosoma mansoni | tar DNA-binding protein | 0.0455 | 0.2556 | 0.3135 |
Mycobacterium ulcerans | hypothetical protein | 0.0315 | 0.1729 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0077 | 0.0069 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0095 | 0.0108 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.