Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.011 | 0.8057 | 0.8057 |
Echinococcus multilocularis | FTZ F1 alpha | 0.011 | 0.8057 | 0.8057 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | nuclear hormone receptor | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | Dual oxidase homolog | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0123 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0123 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.0123 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | Peroxidasin homolog | 0.0123 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0123 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.011 | 0.8057 | 0.8057 |
Echinococcus granulosus | FTZ F1 alpha | 0.011 | 0.8057 | 0.8057 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | 0.0123 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | peroxidasin | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.011 | 0.8057 | 0.8057 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Animal haem peroxidase family protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | nuclear receptor NHR-88 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Animal haem peroxidase family protein | 0.0123 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Blistered cuticle protein 3 | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | 0.0123 | 1 | 1 | |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | ecdysteroid receptor | 0.011 | 0.8057 | 0.8057 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | 0.0123 | 1 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.011 | 0.8057 | 0.8057 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | Peroxidase homolog | 0.0123 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | coup transcription factor | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.011 | 0.8057 | 0.8057 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | nuclear hormone receptor | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.011 | 0.8057 | 0.8057 |
Echinococcus multilocularis | peroxidasin | 0.0123 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Animal haem peroxidase family protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.011 | 0.8057 | 0.8057 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.011 | 0.8057 | 0.8057 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.011 | 0.8057 | 0.8057 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0123 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.011 | 0.8057 | 0.8057 |
Brugia malayi | Animal haem peroxidase family protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.011 | 0.8057 | 0.8057 |
Onchocerca volvulus | Peroxidase homolog | 0.0123 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.011 | 0.8057 | 0.8057 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.011 | 0.8057 | 0.8057 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.