Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0676 | 0.0676 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0221 | 0.022 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0074 | 0.0676 | 0.1757 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0328 | 0.1336 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Toxoplasma gondii | ABC1 family protein | 0.007 | 0.0638 | 0.1602 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0037 | 0.0036 |
Onchocerca volvulus | 0.007 | 0.0638 | 0.2648 | |
Onchocerca volvulus | 0.007 | 0.0638 | 0.2648 | |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0045 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0278 | 0.0267 |
Brugia malayi | beta-lactamase | 0.007 | 0.0638 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0057 | 0.0056 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0037 | 0.0036 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0328 | 0.1336 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0006 | 0.0012 | 0.0011 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.007 | 0.0638 | 0.0515 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.013 | 0.0312 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0278 | 0.0267 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.013 | 0.013 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0045 | 0.0044 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0037 | 0.0036 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.1029 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0638 | 0.0638 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0041 | 0.0041 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0033 | 0.0276 | 0.0264 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0033 | 0.0276 | 0.0264 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0846 | 0.0835 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0474 | 0.4581 | 0.458 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Trichomonas vaginalis | ras GTP exchange factor, son of sevenless, putative | 0.0006 | 0.0012 | 0.0002 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0011 | 0.0057 | 0.0056 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.007 | 0.0638 | 0.0627 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.007 | 0.0638 | 0.0515 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0037 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0037 | 0.0036 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0011 | 0.0057 | 0.012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0846 | 0.0846 |
Mycobacterium leprae | Probable lipase LipE | 0.007 | 0.0638 | 0.0361 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0138 | 0.1293 | 0.1292 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0041 | 0.003 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.007 | 0.0638 | 0.0638 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0328 | 0.0836 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0395 | 0.3809 | 0.3801 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.0328 | 0.0316 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus granulosus | tumor protein p63 | 0.0389 | 0.3751 | 0.3743 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0638 | 0.0638 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0057 | 0.012 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0041 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0276 | 0.0276 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0011 | 0.0057 | 0.0056 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0037 | 0.0025 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0378 | 0.3637 | 0.3629 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0006 | 0.0012 | 0.0011 |
Schistosoma mansoni | smad | 0.0009 | 0.0041 | 0.0041 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.007 | 0.0638 | 0.0515 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0041 | 0.003 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0037 | 0.0025 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0394 | 0.3793 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.007 | 0.0638 | 0.0515 |
Brugia malayi | N-terminal motif family protein | 0.0006 | 0.0012 | 0.0011 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0846 | 0.0835 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0278 | 0.0267 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.013 | 0.0195 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.0638 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0057 | 0.0056 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0676 | 0.1657 |
Brugia malayi | Dihydrofolate reductase | 0.1029 | 1 | 1 |
Echinococcus granulosus | smad | 0.0009 | 0.0041 | 0.003 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0028 | 0.0017 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0041 | 0.0041 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0037 | 0.0036 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0138 | 0.1293 | 0.1292 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0328 | 0.0328 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0037 | 0.0037 |
Trichomonas vaginalis | guanine nucleotide exchange factor, putative | 0.0006 | 0.0012 | 0.0002 |
Onchocerca volvulus | 0.007 | 0.0638 | 0.2648 | |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0057 | 0.0056 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0846 | 0.0835 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0474 | 0.1166 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0037 | 0.0025 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0041 | 0.003 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0057 | 0.012 |
Brugia malayi | MH2 domain containing protein | 0.0138 | 0.1293 | 0.1292 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.013 | 0.0195 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0261 | 0.0547 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0676 | 0.0676 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0328 | 0.0725 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Brugia malayi | RasGEF domain containing protein | 0.0006 | 0.0012 | 0.0011 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.0328 | 0.0775 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0057 | 0.0193 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0278 | 0.0278 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0506 | 0.0506 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0037 | 0.0025 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0012 | 0.0011 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0041 | 0.0041 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0041 | 0.0041 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0041 | 0.003 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0638 | 0.0638 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0037 | 0.0036 |
Brugia malayi | beta-lactamase family protein | 0.007 | 0.0638 | 0.0638 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0045 | 0.0033 |
Mycobacterium leprae | conserved hypothetical protein | 0.007 | 0.0638 | 0.0361 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0057 | 0.0056 |
Onchocerca volvulus | 0.0032 | 0.0261 | 0.1054 | |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.007 | 0.0638 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0037 | 0.0036 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0074 | 0.0676 | 0.1703 |
Mycobacterium tuberculosis | Probable hydrolase | 0.007 | 0.0638 | 0.0515 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0236 | 0.0225 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0394 | 0.3793 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0987 | 0.0987 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.0328 | 0.1336 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0278 | 0.0278 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0074 | 0.0676 | 0.1757 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0037 | 0.0037 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0045 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.012 |
Trichomonas vaginalis | ras GTP exchange factor, putative | 0.0006 | 0.0012 | 0.0002 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0106 | 0.0987 | 0.0987 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0261 | 0.025 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.045 | 0.4348 | 0.4274 |
Loa Loa (eye worm) | PDE1B protein | 0.0011 | 0.0057 | 0.0056 |
Schistosoma mansoni | dihydrofolate reductase | 0.1029 | 1 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0394 | 0.3793 | 1 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus multilocularis | geminin | 0.0183 | 0.1733 | 0.1723 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.013 | 0.0129 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0041 | 0.0041 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.013 | 0.05 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0244 | 0.0233 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0037 | 0.0037 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0037 | 0.0036 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Trichomonas vaginalis | esterase, putative | 0.007 | 0.0638 | 0.2649 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0074 | 0.0676 | 0.1657 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0057 | 0.012 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0037 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0278 | 0.0278 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0045 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0037 | 0.0105 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.007 | 0.0638 | 0.2649 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0057 | 0.012 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0037 | 0.0036 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0378 | 0.3637 | 0.3629 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0011 | 0.0057 | 0.0045 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0011 | 0.0057 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0278 | 0.0278 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.0638 | 0.2649 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0638 | 0.0638 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0037 | 0.0037 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0011 | 0.0057 | 0.0045 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.007 | 0.0638 | 0.0515 |
Trypanosoma cruzi | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.171 | 0.1709 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0106 | 0.0987 | 0.0987 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0278 | 0.0267 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0028 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0659 | 0.0659 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0037 | 0.0025 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0236 | 0.0236 |
Trichomonas vaginalis | ras GTP exchange factor, putative | 0.0006 | 0.0012 | 0.0002 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0261 | 0.025 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0006 | 0.0012 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0278 | 0.0278 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.007 | 0.0638 | 0.0515 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0221 | 0.022 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus multilocularis | smad | 0.0009 | 0.0041 | 0.003 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0092 | 0.0846 | 0.0845 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0041 | 0.003 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0041 | 0.0041 |
Echinococcus granulosus | geminin | 0.0183 | 0.1733 | 0.1723 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.0328 | 0.0316 |
Schistosoma mansoni | camp-dependent rap1 guanine-nucleotide exchange factor | 0.0006 | 0.0009 | 0.0009 |
Chlamydia trachomatis | dihydrofolate reductase | 0.1029 | 1 | 0.5 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.012 |
Brugia malayi | RasGEF domain containing protein | 0.0006 | 0.0012 | 0.0011 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.0638 | 0.1658 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0011 | 0.0057 | 0.0056 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.0638 | 0.1658 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0659 | 0.0659 |
Brugia malayi | RasGEF domain containing protein | 0.0006 | 0.0012 | 0.0011 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0106 | 0.0987 | 0.0987 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.007 | 0.0638 | 0.0638 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.013 | 0.05 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.1029 | 1 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.007 | 0.0638 | 0.0627 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0006 | 0.0012 | 0.0012 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0074 | 0.0676 | 0.1657 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0261 | 0.0261 |
Trypanosoma brucei | hypothetical protein, conserved | 0.007 | 0.0638 | 0.1556 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0037 | 0.0025 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0846 | 0.0835 |
Onchocerca volvulus | 0.0057 | 0.0506 | 0.209 | |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0041 | 0.0041 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0057 | 0.0056 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0057 | 0.012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0846 | 0.0846 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0037 | 0.0036 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0041 | 0.0041 |
Onchocerca volvulus | 0.0249 | 0.2378 | 1 | |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0037 | 0.0037 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0261 | 0.0261 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Loa Loa (eye worm) | beta-lactamase | 0.007 | 0.0638 | 0.0638 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0261 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0012 | 0.0011 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.013 | 0.0129 |
Echinococcus granulosus | dnaJ subfamily B | 0.0395 | 0.3809 | 0.3801 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0638 | 0.0638 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.0288 | 0.016 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0006 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0278 | 0.0278 |
Brugia malayi | N-terminal motif family protein | 0.0006 | 0.0012 | 0.0011 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0278 | 0.0278 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0092 | 0.0846 | 0.0845 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0261 | 0.0261 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0037 | 0.0025 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.1029 | 1 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0394 | 0.3793 | 1 |
Schistosoma mansoni | ras GTP exchange factor | 0.0006 | 0.0012 | 0.0012 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0074 | 0.0676 | 0.1657 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0394 | 0.3793 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0057 | 0.0056 |
Onchocerca volvulus | 0.0009 | 0.0037 | 0.0105 | |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.1029 | 1 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0506 | 0.0506 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0041 | 0.0041 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0028 | 0.0017 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0278 | 0.0267 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0057 | 0.0193 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.013 | 0.0312 |
Mycobacterium tuberculosis | Conserved protein | 0.007 | 0.0638 | 0.0515 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0045 | 0.0033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0057 | 0.0193 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0328 | 0.0725 |
Brugia malayi | Smad1 | 0.0009 | 0.0041 | 0.0041 |
Trypanosoma cruzi | cyclic nucleotide phosphodiesterase | 0.0011 | 0.0057 | 0.012 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.013 | 0.0195 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0394 | 0.3793 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.007 | 0.0638 | 0.0515 |
Brugia malayi | hypothetical protein | 0.0048 | 0.0419 | 0.0418 |
Brugia malayi | Inositol-1 | 0.0039 | 0.0328 | 0.0327 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.1733 | 0.1733 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.0659 | 0.0659 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0028 | 0.0028 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.0638 | 0.1556 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0006 | 0.0012 | 0.0012 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.0328 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0236 | 0.0236 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.0638 | 0.2649 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0221 | 0.0221 |
Brugia malayi | N-terminal motif family protein | 0.018 | 0.171 | 0.1709 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0536 | 0.0536 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.013 | 0.0118 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Trichomonas vaginalis | set domain proteins, putative | 0.0249 | 0.2378 | 1 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0006 | 0.0012 | 0.0012 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.013 | 1 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0011 | 0.0057 | 0.0045 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.012 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0028 | 0.0017 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0236 | 0.0225 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.013 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.007 | 0.0638 | 0.0638 |
Echinococcus granulosus | dihydrofolate reductase | 0.1029 | 1 | 1 |
Onchocerca volvulus | 0.0028 | 0.0221 | 0.0884 | |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0328 | 0.0836 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0638 | 0.0638 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.013 | 0.0118 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0261 | 0.0261 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.013 | 0.3735 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.013 | 0.0195 |
Brugia malayi | Pre-SET motif family protein | 0.0219 | 0.2084 | 0.2084 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0041 | 0.0041 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.0328 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0328 | 0.0328 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.0328 | 0.0201 |
Plasmodium vivax | hypothetical protein, conserved | 0.007 | 0.0638 | 0.1556 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0074 | 0.0676 | 0.1657 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0057 |
Mycobacterium tuberculosis | Conserved protein | 0.007 | 0.0638 | 0.0515 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0041 | 0.003 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.007 | 0.0638 | 0.0515 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0041 | 0.0041 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0057 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.1733 | 0.1733 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.0328 | 0.0327 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.018 | 0.171 | 0.7176 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0057 | 0.012 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.0638 | 0.2649 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0011 | 0.0057 | 0.012 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0011 | 0.0057 | 0.0045 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0278 | 0.0278 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0261 | 0.0261 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Mycobacterium ulcerans | beta-lactamase | 0.007 | 0.0638 | 0.0515 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.007 | 0.0638 | 0.2649 |
Mycobacterium ulcerans | lipase LipD | 0.007 | 0.0638 | 0.0515 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0037 | 0.0025 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.013 | 0.013 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0278 | 0.0267 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.007 | 0.0638 | 0.0638 |
Echinococcus multilocularis | dihydrofolate reductase | 0.1029 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0057 | 0.0056 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0846 | 0.0846 |
Schistosoma mansoni | hypothetical protein | 0.0395 | 0.3809 | 0.3809 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0037 | 0.0025 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0044 | 0.0043 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.013 | 0.0248 |
Mycobacterium tuberculosis | Conserved protein | 0.007 | 0.0638 | 0.0515 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0057 | 0.0193 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0261 | 0.0598 |
Brugia malayi | follicle stimulating hormone receptor | 0.0474 | 0.4581 | 0.458 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0219 | 0.2084 | 0.2084 |
Echinococcus multilocularis | tumor protein p63 | 0.0389 | 0.3751 | 0.3743 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0057 | 0.012 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0261 | 0.025 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.