Detailed information for compound 767806

Basic information

Technical information
  • TDR Targets ID: 767806
  • Name: N-[5-[(4-bromophenyl)methyl]-1,3-thiazol-2-yl ]-2-(2-methylphenoxy)acetamide
  • MW: 417.319 | Formula: C19H17BrN2O2S
  • H donors: 1 H acceptors: 2 LogP: 5.17 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ncc(s1)Cc1ccc(cc1)Br)COc1ccccc1C
  • InChi: 1S/C19H17BrN2O2S/c1-13-4-2-3-5-17(13)24-12-18(23)22-19-21-11-16(25-19)10-14-6-8-15(20)9-7-14/h2-9,11H,10,12H2,1H3,(H,21,22,23)
  • InChiKey: JTDJLNUBRJYKLR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[5-[(4-bromophenyl)methyl]thiazol-2-yl]-2-(2-methylphenoxy)acetamide
  • N-[5-[(4-bromophenyl)methyl]-2-thiazolyl]-2-(2-methylphenoxy)acetamide
  • N-[5-(4-bromobenzyl)thiazol-2-yl]-2-(2-methylphenoxy)acetamide
  • N-[5-[(4-bromophenyl)methyl]-1,3-thiazol-2-yl]-2-(2-methylphenoxy)ethanamide
  • N-[5-(4-Bromo-benzyl)-thiazol-2-yl]-2-o-tolyloxy-acetamide
  • Oprea1_231393
  • Oprea1_250093
  • BAS 01055623

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0228 0.0752
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0435 0.1262
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0573 0.1952
Onchocerca volvulus 0.0071 0.1378 0.6846
Brugia malayi hypothetical protein 0.002 0.0228 0.0661
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.1928 0.5595
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0013 0.00000000078197
Mycobacterium tuberculosis Conserved protein 0.0071 0.1378 0.1261
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0228 0.0661
Schistosoma mansoni hypothetical protein 0.0029 0.0435 0.1481
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.1215 0.4139
Giardia lamblia Kinase, PLK 0.0098 0.2013 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0082 0.0001
Schistosoma mansoni ap endonuclease 0.0019 0.0207 0.0705
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.3447 1
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0227 0.0773
Schistosoma mansoni DNA helicase recq1 0.001 0.0013 0.0044
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0207 0.0649
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0592 0.2644
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0082 0.0001
Schistosoma mansoni loxhd1 0.002 0.0228 0.0776
Schistosoma mansoni lipoxygenase 0.0118 0.2466 0.84
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0082 0.0001
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.1378 0.1261
Trichomonas vaginalis esterase, putative 0.0071 0.1378 0.6713
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0082 0.0405
Toxoplasma gondii ABC1 family protein 0.0071 0.1378 1
Brugia malayi isocitrate dehydrogenase 0.0016 0.0134 0.0389
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0592 0.2644
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0592 0.2644
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.1215 0.8606
Echinococcus granulosus jumonji domain containing protein 0.004 0.0692 0.2008
Mycobacterium tuberculosis Conserved protein 0.0071 0.1378 0.1261
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0592 0.1719
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0207 0.0601
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0346 0.1371
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.1378 0.6713
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.1378 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0134 0.0272
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0134 0.0272
Schistosoma mansoni alpha-glucosidase 0.0139 0.2936 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.2013 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0228 0.5092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.1378 0.1261
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0158 0.1062
Brugia malayi Bromodomain containing protein 0.0029 0.0435 0.1262
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0592 0.1719
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1378 0.4695
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1378 0.6713
Echinococcus granulosus bloom syndrome protein 0.0025 0.0346 0.1005
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0228 0.0661
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.2013 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0013 0.0037
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0207 0.0649
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0821 0.2796
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.1378 0.1261
Mycobacterium leprae Probable lipase LipE 0.0071 0.1378 0.5
Trypanosoma brucei glucosidase, putative 0.0036 0.0592 0.2644
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1378 0.4695
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0168 0.3592 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0207 0.0649
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0821 0.2381
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.1215 0.8804
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0013 0.0037
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.1378 0.1261
Brugia malayi PHD-finger family protein 0.0029 0.0435 0.1262
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.2013 0.6858
Onchocerca volvulus 0.002 0.0228 0.1131
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.2013 0.5841
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0573 0.1595
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0162 0.0228
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0821 0.2381
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0134 0.0272
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0134 0.2874
Plasmodium falciparum phd finger protein, putative 0.0029 0.0435 1
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.1134 0.3156
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0228 0.0661
Schistosoma mansoni DNA helicase recq5 0.001 0.0013 0.0044
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0346 0.1005
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0082 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0435 0.2417
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0134 0.0389
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1378 0.6713
Loa Loa (eye worm) hypothetical protein 0.002 0.0228 0.0634
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0134 0.0888
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0207 0.0649
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0207 0.0074
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0435 0.1262
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1378 0.6713
Echinococcus granulosus RUN 0.002 0.0228 0.0661
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0207 0.0357
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0207 0.5
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.2466 0.7155
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0821 0.2381
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.2013 0.5503
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Schistosoma mansoni lipoxygenase 0.0083 0.1657 0.5645
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.1215 0.5868
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.2013 0.5841
Schistosoma mansoni alpha-glucosidase 0.0139 0.2936 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0207 0.0601
Schistosoma mansoni alpha glucosidase 0.0036 0.0592 0.2018
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0134 0.0389
Loa Loa (eye worm) hypothetical protein 0.0071 0.1378 0.3837
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0346 0.1371
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.1378 0.3999
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0592 0.1649
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0207 0.0586
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0207 0.097
Loa Loa (eye worm) hypothetical protein 0.0071 0.1378 0.3837
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0013 0.0037
Onchocerca volvulus Alhambra homolog 0.0029 0.0435 0.216
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0821 0.2796
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.2013 0.5841
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.1215 0.3525
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0592 0.2644
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0082 0.0237
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0168 0.3592 1
Schistosoma mansoni rab6-interacting 0.002 0.0228 0.0776
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0592 0.2644
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0134 0.0457
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0573 0.1952
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0592 0.2644
Loa Loa (eye worm) hypothetical protein 0.0168 0.3592 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.1378 0.3837
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0207 0.0601
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.1215 0.8606
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0435 0.1211
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0692 0.2008
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1378 0.6713
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0573 0.1662
Schistosoma mansoni ap endonuclease 0.0019 0.0207 0.0705
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0134 0.0389
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.2466 0.7155
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0013 0.0037
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0592 0.4244
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0592 0.2644
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.1378 0.1261
Mycobacterium ulcerans lipase LipD 0.0071 0.1378 1
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0134 0.0389
Loa Loa (eye worm) hypothetical protein 0.0071 0.1378 0.3837
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0592 0.2644
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0821 0.2285
Loa Loa (eye worm) hypothetical protein 0.0029 0.0435 0.1211
Brugia malayi beta-lactamase family protein 0.0071 0.1378 0.3999
Onchocerca volvulus 0.0071 0.1378 0.6846
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.1215 0.3525
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0228 0.0661
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.2013 1
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0885 0.4158
Mycobacterium ulcerans beta-lactamase 0.0071 0.1378 1
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0228 0.0661
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.1378 0.3999
Schistosoma mansoni kinase 0.005 0.0914 0.3114
Brugia malayi jmjC domain containing protein 0.0095 0.1928 0.5595
Toxoplasma gondii exonuclease III APE 0.0019 0.0207 0.1422
Echinococcus granulosus peregrin 0.0029 0.0435 0.1262
Loa Loa (eye worm) hypothetical protein 0.0126 0.2637 0.7343
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0592 0.2644
Loa Loa (eye worm) hypothetical protein 0.005 0.0904 0.2516
Loa Loa (eye worm) doublecortin family protein 0.002 0.0228 0.0634
Loa Loa (eye worm) hypothetical protein 0.0071 0.1378 0.3837
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0134 0.0389
Onchocerca volvulus 0.0071 0.1378 0.6846
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0435 0.309
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.1378 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.1378 0.3837
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0013 0.0037
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0207 0.0576
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0277 0.6269
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1378 0.6713
Brugia malayi beta-lactamase 0.0071 0.1378 0.3999
Brugia malayi beta-lactamase family protein 0.0071 0.1378 0.3999
Loa Loa (eye worm) RecQ helicase 0.0025 0.0346 0.0964
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.3447 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0435 0.1481
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0082 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0207 0.0649
Giardia lamblia PHD finger protein 15 0.0029 0.0435 0.2109
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0207 0.5
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.3447 1
Echinococcus multilocularis RUN 0.002 0.0228 0.0661
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.1378 0.1261
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0228 0.0661
Onchocerca volvulus 0.0093 0.19 0.9437
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.2013 0.5605
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0592 0.2644
Mycobacterium tuberculosis Conserved protein 0.0071 0.1378 0.1261
Schistosoma mansoni polycystin 1-related 0.002 0.0228 0.0776
Trypanosoma brucei polo-like protein kinase 0.0098 0.2013 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0134 0.0272
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.1378 0.1261
Schistosoma mansoni rab6-interacting 0.002 0.0228 0.0776
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0592 0.1455
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1378 0.6713
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.3447 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.1215 0.1096
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0592 0.1455
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1378 0.6713
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Mycobacterium ulcerans hypothetical protein 0.0071 0.1378 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0821 0.2796
Loa Loa (eye worm) hypothetical protein 0.0013 0.0082 0.0227
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.2013 1
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0885 0.4158
Brugia malayi hypothetical protein 0.002 0.0228 0.0661
Loa Loa (eye worm) hypothetical protein 0.0071 0.1378 0.3837
Leishmania major hypothetical protein, conserved 0.0071 0.1378 0.6713
Brugia malayi jmjC domain containing protein 0.0035 0.0573 0.1662
Loa Loa (eye worm) hypothetical protein 0.002 0.0228 0.0634
Mycobacterium leprae conserved hypothetical protein 0.0071 0.1378 0.5
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0207 0.0649
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.1928 0.5595
Schistosoma mansoni hypothetical protein 0.002 0.0228 0.0776
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0435 0.309
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0592 0.2644
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2013 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0821 0.2381
Plasmodium vivax hypothetical protein, conserved 0.0071 0.1378 1
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.1215 0.4139
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0573 0.1662
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0821 0.2381
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0592 0.1719
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0013 0.0037
Onchocerca volvulus 0.002 0.0228 0.1131
Schistosoma mansoni jumonji domain containing protein 0.0075 0.1486 0.5063
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0592 0.2644
Loa Loa (eye worm) beta-lactamase 0.0071 0.1378 0.3837
Brugia malayi Doublecortin family protein 0.002 0.0228 0.0661
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0134 0.0389
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0134 0.0373
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0207 0.46
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.1215 0.8606
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.3447 0.9596
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0134 0.0389
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0134 0.0272
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0134 0.0888
Echinococcus multilocularis peregrin 0.0029 0.0435 0.1262
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0013 0.0036
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.1378 0.3999
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0346 0.1005

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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