Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.1325 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1082 | 0.4325 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.013 | 0.0519 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.2502 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1088 | 0.1031 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.1325 | 0.1314 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.1325 | 0.1277 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0205 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1325 | 0.1309 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.1325 | 0.5296 |
Brugia malayi | beta-lactamase | 0.0037 | 0.1325 | 0.1314 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.2502 | 0.2685 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.1088 | 0.4036 |
Trichomonas vaginalis | set domain proteins, putative | 0.0242 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1325 | 0.1309 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1325 | 0.1309 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.1325 | 0.1314 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.1088 | 0.4346 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.1325 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.1088 | 0.4036 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.2502 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.1325 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.1012 | 0.0948 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.1325 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2502 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.1325 | 0.1277 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.1325 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.2502 | 0.2689 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.1325 | 0.2208 |
Onchocerca volvulus | 0.0031 | 0.1088 | 0.0084 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.1325 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.2502 | 0.2685 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.2165 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.1325 | 0.1277 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0212 | 0.8762 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.1325 | 0.1277 |
Brugia malayi | RNA binding protein | 0.0064 | 0.2502 | 0.2689 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.1082 | 0.4014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.1088 | 0.4346 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1325 | 0.1309 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.1013 | 0.3723 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2502 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1325 | 0.1309 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.1012 | 0.4043 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.1325 | 0.1309 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.1325 | 0.5039 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.1088 | 0.4036 |
Onchocerca volvulus | 0.0037 | 0.1325 | 0.0349 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2502 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.1325 | 0.5039 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.1325 | 0.1309 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.2445 | 0.9771 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.1325 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1082 | 0.4325 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.1088 | 0.4346 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.1325 | 0.1277 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.2502 | 0.2685 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.1082 | 0.4014 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.1325 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0205 | 0.0318 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.1325 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.1325 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.1325 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1325 | 0.1309 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.1088 | 0.1036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2502 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.9678 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2502 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.1325 | 0.1277 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.1012 | 0.0943 |
Brugia malayi | Pre-SET motif family protein | 0.0212 | 0.8762 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.1325 | 0.5 |
Onchocerca volvulus | 0.0037 | 0.1325 | 0.0349 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.1088 | 0.4346 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.1325 | 0.1314 |
Onchocerca volvulus | 0.0037 | 0.1325 | 0.0349 | |
Brugia malayi | TAR-binding protein | 0.0064 | 0.2502 | 0.2689 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.1325 | 0.5296 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.