Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.63 | 0.63 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.003 | 0.1983 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.1983 | 0.1983 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0075 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0075 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.63 | 0.63 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.63 | 0.63 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.63 | 0.63 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.1983 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0075 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0075 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.003 | 0.1983 | 0.1983 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.1983 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.1983 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0059 | 0.7163 | 0.7163 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0075 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.63 | 0.63 |
Echinococcus multilocularis | histone lysine N methyltransferase NSD3 | 0.0039 | 0.3573 | 0.3573 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.1983 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0059 | 0.7163 | 0.7163 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0105 | 0.0105 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0059 | 0.7163 | 0.7163 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.63 | 0.63 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0075 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.3848 | 0.3848 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 1 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.003 | 0.1983 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.63 | 0.63 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.63 | 0.63 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.7163 | 0.7163 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.3848 | 0.3848 |
Echinococcus granulosus | histone lysine N methyltransferase NSD3 | 0.0039 | 0.3573 | 0.3573 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.003 | 0.1983 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0075 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.1983 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.63 | 0.63 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.3848 | 0.3848 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 1 | 1 |
Schistosoma mansoni | SET domain protein | 0.0039 | 0.3573 | 0.3573 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.