Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | zinc finger protein | 0.0022 | 0.0118 | 0.0546 |
Schistosoma mansoni | lamin | 0.003 | 0.0466 | 0.2145 |
Echinococcus multilocularis | lamin | 0.003 | 0.0466 | 0.2325 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.089 | 0.3531 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.089 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.089 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1001 | 0.3972 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0066 | 0.2002 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.1112 | 0.4413 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.0998 | 0.2673 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1202 | 0.4769 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0466 | 0.1847 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0029 | 0.0114 |
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.089 | 0.5 |
Onchocerca volvulus | 0.004 | 0.089 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0168 | 0.0774 |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.089 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.089 | 0.3531 |
Brugia malayi | Bromodomain containing protein | 0.0083 | 0.2721 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.004 | 0.089 | 0.5 |
Onchocerca volvulus | 0.004 | 0.089 | 1 | |
Brugia malayi | beta-lactamase | 0.004 | 0.089 | 0.2215 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.089 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.089 | 0.4444 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.089 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0258 | 0.1287 |
Schistosoma mansoni | lamin | 0.003 | 0.0466 | 0.2145 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.089 | 0.3531 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0168 | 0.0667 |
Schistosoma mansoni | bromodomain containing protein | 0.007 | 0.2171 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.004 | 0.089 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.089 | 0.3531 |
Mycobacterium leprae | conserved hypothetical protein | 0.004 | 0.089 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.089 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0466 | 0.2145 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.089 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.089 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0258 | 0.1188 |
Trichomonas vaginalis | esterase, putative | 0.004 | 0.089 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.004 | 0.089 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.089 | 0.3531 |
Echinococcus multilocularis | musashi | 0.003 | 0.0466 | 0.2325 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.089 | 0.2215 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0886 | 0.4427 |
Echinococcus granulosus | lamin | 0.003 | 0.0466 | 0.2325 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0466 | 0.2325 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.252 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0066 | 0.2002 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0258 | 0.1287 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.089 | 0.5 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0466 | 0.0411 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0886 | 0.4427 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.089 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.089 | 0.41 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0466 | 0.0411 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.089 | 0.2215 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.089 | 0.3531 |
Onchocerca volvulus | 0.004 | 0.089 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0442 | 0.1755 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.089 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.004 | 0.089 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.089 | 0.41 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0466 | 0.2325 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0466 | 0.1847 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.089 | 0.2215 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0466 | 0.2325 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.089 | 0.3531 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.089 | 0.3531 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0466 | 0.1847 |
Echinococcus granulosus | zinc finger protein | 0.0022 | 0.0118 | 0.0592 |
Mycobacterium ulcerans | beta-lactamase | 0.004 | 0.089 | 0.5 |
Echinococcus multilocularis | zinc finger protein | 0.0022 | 0.0118 | 0.0592 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.089 | 0.4444 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.