Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.351 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0764 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0764 | 0.0764 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.351 | 0.2974 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.351 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.351 | 0.3622 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0764 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0764 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.8347 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0161 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0764 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.351 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0764 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.351 | 0.3622 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0764 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0764 | 0.0764 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0764 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0764 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.4995 | 0.5 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0764 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.351 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0764 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.351 | 0.2974 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0764 | 0.5 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0764 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0073 | 0.351 | 0.351 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.8347 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0764 | 0.5 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0764 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.