Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0155 | 0.3215 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0192 | 0.4054 | 0.3992 |
Schistosoma mansoni | hypothetical protein | 0.0297 | 0.6431 | 0.6395 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0453 | 0.9997 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0784 | 0.0687 |
Leishmania major | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Brugia malayi | MBOAT family protein | 0.0044 | 0.0681 | 0.1853 |
Leishmania major | hypothetical protein, conserved | 0.0044 | 0.0681 | 0.4866 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.3051 | 0.2978 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0044 | 0.0681 | 0.1853 |
Trypanosoma cruzi | GUP1, putative | 0.0044 | 0.0681 | 0.4866 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.0784 | 0.0687 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0784 | 0.0687 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0681 | 0.4866 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0681 | 0.4866 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0056 | 0.0938 | 0.0843 |
Schistosoma mansoni | hypothetical protein | 0.0155 | 0.3215 | 0.3145 |
Brugia malayi | MBOAT family protein | 0.0044 | 0.0681 | 0.1853 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.0784 | 0.0687 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0044 | 0.0681 | 0.5282 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.3051 | 0.9471 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1289 | 0.1197 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0144 | 0.2956 | 0.2883 |
Onchocerca volvulus | 0.0044 | 0.0681 | 0.4866 | |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0056 | 0.0938 | 0.0843 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0044 | 0.0681 | 0.0583 |
Echinococcus granulosus | lysophospholipid acyltransferase 7 | 0.0044 | 0.0681 | 0.0583 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0784 | 0.2185 |
Loa Loa (eye worm) | hhat protein | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0056 | 0.0938 | 0.0843 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0681 | 0.0583 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0044 | 0.0681 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1289 | 0.1197 |
Trichomonas vaginalis | porcupine, putative | 0.0044 | 0.0681 | 0.4866 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1289 | 0.1197 |
Mycobacterium leprae | conserved hypothetical protein | 0.0071 | 0.1289 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1289 | 1 |
Onchocerca volvulus | 0.0071 | 0.1289 | 1 | |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0666 | 0.474 |
Loa Loa (eye worm) | hypothetical protein | 0.0409 | 0.8988 | 0.8981 |
Mycobacterium ulcerans | lipase LipD | 0.0071 | 0.1289 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0071 | 0.1289 | 0.5 |
Leishmania major | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0708 | 0.061 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1289 | 0.1197 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0453 | 0.9997 | 1 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0044 | 0.0681 | 0.0583 |
Entamoeba histolytica | hypothetical protein | 0.0155 | 0.3215 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0071 | 0.1289 | 0.1197 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0071 | 0.1289 | 0.1197 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0708 | 0.061 |
Entamoeba histolytica | hypothetical protein | 0.0155 | 0.3215 | 1 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | membrane bound acyltransferase:hhat | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0056 | 0.0938 | 0.0843 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0044 | 0.0681 | 0.0583 |
Entamoeba histolytica | hypothetical protein | 0.0155 | 0.3215 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0155 | 0.3215 | 0.3145 |
Loa Loa (eye worm) | hhat protein | 0.0044 | 0.0681 | 0.0583 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0056 | 0.0938 | 0.0843 |
Onchocerca volvulus | 0.0071 | 0.1289 | 1 | |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.1289 | 0.3807 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0784 | 0.2185 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0071 | 0.1289 | 0.3807 |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.3051 | 0.2978 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0044 | 0.0681 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.1289 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.0784 | 0.0687 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0708 | 0.061 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0071 | 0.1289 | 0.1197 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.0784 | 0.0687 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.1289 | 1 |
Schistosoma mansoni | membrane-bound acyltransferase/hhat | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | Membrane bound O acyl transferase, MBOAT | 0.0044 | 0.0681 | 0.0583 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0666 | 0.474 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0681 | 0.4866 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0666 | 0.5165 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0071 | 0.1289 | 0.5 |
Schistosoma mansoni | leukocyte receptor cluster (lrc) member 4 protein | 0.0044 | 0.0681 | 0.0583 |
Onchocerca volvulus | 0.0049 | 0.0784 | 0.5739 | |
Brugia malayi | hypothetical protein | 0.0155 | 0.3215 | 1 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0044 | 0.0681 | 0.5282 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0192 | 0.4054 | 0.3992 |
Trichomonas vaginalis | transmembrane protein nessy, putative | 0.0044 | 0.0681 | 0.4866 |
Trypanosoma cruzi | GUP1, putative | 0.0044 | 0.0681 | 0.4866 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0666 | 0.5165 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.1289 | 0.3807 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0583 | 1 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0044 | 0.0681 | 0.024 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.1289 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0708 | 0.061 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0681 | 0.0583 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0666 | 0.0568 |
Mycobacterium leprae | Probable lipase LipE | 0.0071 | 0.1289 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.1289 | 1 |
Treponema pallidum | alginate O-acetylation protein (algI) | 0.0044 | 0.0681 | 0.5 |
Leishmania major | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0708 | 0.061 |
Loa Loa (eye worm) | beta-lactamase | 0.0071 | 0.1289 | 0.1197 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0583 | 0.8304 |
Leishmania major | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0044 | 0.0681 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.9997 | 1 |
Echinococcus granulosus | protein cysteine N palmitoyltransferase | 0.0044 | 0.0681 | 0.0583 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.0784 | 0.5739 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0708 | 0.061 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0044 | 0.0681 | 0.0583 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1289 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.1289 | 1 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0044 | 0.0681 | 0.1853 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.3051 | 0.2978 |
Loa Loa (eye worm) | MBCTL1 | 0.0056 | 0.0938 | 0.0843 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0155 | 0.3215 | 0.3145 |
Schistosoma mansoni | zinc finger protein | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.0784 | 0.0687 |
Brugia malayi | MBOAT family protein | 0.0044 | 0.0681 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0681 | 0.0583 |
Brugia malayi | diacylglycerol acyltransferase | 0.0044 | 0.0681 | 0.1853 |
Leishmania major | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0708 | 0.194 |
Brugia malayi | MBOAT family protein | 0.0044 | 0.0681 | 0.1853 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Echinococcus granulosus | Membrane bound O acyl transferase MBOAT | 0.0044 | 0.0681 | 0.0583 |
Loa Loa (eye worm) | membrane bound O-acyltransferase domain containing 1 | 0.0044 | 0.0681 | 0.0583 |
Loa Loa (eye worm) | MBOAT family protein | 0.0044 | 0.0681 | 0.0583 |
Echinococcus multilocularis | protein cysteine N palmitoyltransferase | 0.0044 | 0.0681 | 0.0583 |
Brugia malayi | MBOAT family protein | 0.0044 | 0.0681 | 0.1853 |
Mycobacterium ulcerans | hypothetical protein | 0.0071 | 0.1289 | 0.5 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0056 | 0.0938 | 0.268 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0453 | 0.9997 | 1 |
Loa Loa (eye worm) | MBOAT family protein | 0.0044 | 0.0681 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0938 | 0.0843 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0708 | 0.061 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0044 | 0.0681 | 0.0583 |
Loa Loa (eye worm) | MBOAT family protein | 0.0044 | 0.0681 | 0.0583 |
Brugia malayi | beta-lactamase | 0.0071 | 0.1289 | 0.3807 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0044 | 0.0681 | 0.0583 |
Mycobacterium ulcerans | beta-lactamase | 0.0071 | 0.1289 | 0.5 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.0784 | 0.0687 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0784 | 0.0687 |
Entamoeba histolytica | hypothetical protein | 0.0044 | 0.0681 | 0.1853 |
Plasmodium vivax | hypothetical protein, conserved | 0.0071 | 0.1289 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0155 | 0.3215 | 0.3145 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0044 | 0.0681 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1289 | 0.1197 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0708 | 0.061 |
Entamoeba histolytica | vacuolar protein sorting 26 | 0.0044 | 0.0681 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0681 | 0.0583 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0044 | 0.0681 | 0.1853 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0071 | 0.1289 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0071 | 0.1289 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1289 | 0.1197 |
Brugia malayi | Hhat protein | 0.0044 | 0.0681 | 0.1853 |
Toxoplasma gondii | hypothetical protein | 0.0044 | 0.0681 | 0.5282 |
Toxoplasma gondii | ABC1 family protein | 0.0071 | 0.1289 | 1 |
Echinococcus multilocularis | lysophospholipid acyltransferase 7 | 0.0044 | 0.0681 | 0.0583 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0044 | 0.0681 | 0.4866 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.1289 | 0.1197 |
Echinococcus granulosus | membrane bound acyltransferase:hhat | 0.0044 | 0.0681 | 0.0583 |
Onchocerca volvulus | 0.0071 | 0.1289 | 1 | |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0583 | 0.1539 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0044 | 0.0681 | 0.0583 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1289 | 1 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0044 | 0.0681 | 0.0583 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.1289 | 0.1197 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.