Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0344 | 0.0335 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0084 | 0.0504 | 0.0739 |
Brugia malayi | bHLH-PAS transcription factor | 0.0042 | 0.01 | 0.0191 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.0402 | 0.0586 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0212 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0084 | 0.0504 | 0.1064 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0084 | 0.0504 | 0.0739 |
Echinococcus granulosus | snurportin 1 | 0.0303 | 0.2659 | 0.3958 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0177 | 0.1422 | 0.2109 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0109 | 0.0759 | 0.1602 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.1529 | 0.1521 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0986 | 0.0978 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0084 | 0.0504 | 0.1047 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.0278 | 0.0569 |
Brugia malayi | hypothetical protein | 0.0192 | 0.1566 | 0.3292 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0068 | 0.0356 | 0.8447 |
Onchocerca volvulus | 0.0091 | 0.0579 | 0.3151 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0177 | 0.1422 | 0.1413 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.0402 | 0.0586 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0084 | 0.0504 | 0.1047 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0177 | 0.1422 | 0.3001 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0177 | 0.1422 | 0.2109 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0177 | 0.1422 | 0.3001 |
Brugia malayi | MH2 domain containing protein | 0.0241 | 0.2047 | 0.4311 |
Brugia malayi | nuclear receptor NHR-88 | 0.0177 | 0.1422 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0389 | 0.3504 | 0.3498 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0241 | 0.2047 | 0.4322 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0177 | 0.1422 | 0.2988 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0716 | 0.6704 | 1 |
Echinococcus granulosus | Ankyrin | 0.0034 | 0.0019 | 0.0014 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.037 | 0.3313 | 0.4934 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.041 | 0.5 |
Echinococcus multilocularis | snurportin 1 | 0.0303 | 0.2659 | 0.3958 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0177 | 0.1422 | 0.1413 |
Onchocerca volvulus | 0.014 | 0.1057 | 0.5752 | |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0303 | 0.2659 | 0.5614 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0061 | 0.0278 | 0.0269 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0212 | 0.0203 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0154 | 0.1196 | 0.2526 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.1529 | 0.1521 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.0212 | 0.0303 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0034 | 0.0016 | 0.001 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0515 | 0.4736 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0084 | 0.0504 | 0.0495 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0177 | 0.1422 | 0.3001 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0133 | 0.0986 | 0.2067 |
Loa Loa (eye worm) | cytochrome P450 | 0.0033 | 0.0009 | 0.002 |
Onchocerca volvulus | 0.0091 | 0.0579 | 0.3151 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0177 | 0.1422 | 0.2109 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0034 | 0.0019 | 0.001 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0241 | 0.2047 | 0.4322 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0278 | 0.241 | 0.3585 |
Loa Loa (eye worm) | doublecortin family protein | 0.014 | 0.1057 | 0.2232 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0109 | 0.0759 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Schistosoma mansoni | coup transcription factor | 0.0177 | 0.1422 | 0.1413 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.028 | 0.2427 | 0.3611 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.1566 | 0.3306 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0034 | 0.0016 | 0.001 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0081 | 0.0477 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.0278 | 0.0402 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.0212 | 0.0303 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0084 | 0.0504 | 0.0739 |
Brugia malayi | nuclear receptor NHR-88 | 0.0084 | 0.0504 | 0.1047 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0042 | 0.0096 | 0.0203 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.0204 | 0.029 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.037 | 0.3313 | 0.4934 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.0402 | 0.0586 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0986 | 0.0978 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0602 | 0.1272 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0034 | 0.0016 | 0.0007 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0177 | 0.1422 | 0.7735 |
Brugia malayi | Death domain containing protein | 0.0034 | 0.0016 | 0.0014 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0084 | 0.0504 | 0.1047 |
Brugia malayi | Protein kinase domain containing protein | 0.0034 | 0.0016 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | nuclear receptor | 0.0084 | 0.0504 | 0.0495 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0177 | 0.1422 | 0.7735 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0091 | 0.0579 | 0.1205 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0091 | 0.0579 | 0.1205 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.0212 | 0.0448 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0489 | 0.448 | 0.4475 |
Schistosoma mansoni | nuclear hormone receptor | 0.0084 | 0.0504 | 0.0495 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0057 | 0.0246 | 0.0236 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0389 | 0.3504 | 0.522 |
Echinococcus multilocularis | jun protein | 0.028 | 0.2427 | 0.3611 |
Schistosoma mansoni | survival motor neuron protein | 0.0057 | 0.0241 | 0.0232 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.014 | 0.1057 | 0.1565 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0602 | 0.1272 |
Brugia malayi | hypoxia-induced factor 1 | 0.0177 | 0.142 | 0.2984 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0177 | 0.1422 | 0.2988 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.0278 | 0.0402 |
Onchocerca volvulus | 0.014 | 0.1057 | 0.5752 | |
Echinococcus granulosus | serotonin transporter | 0.0109 | 0.0759 | 0.1119 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0344 | 0.0499 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.014 | 0.1057 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0234 | 0.1981 | 0.4184 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.0402 | 0.0393 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0091 | 0.0579 | 0.1223 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.041 | 0.0599 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0344 | 0.0335 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0986 | 0.0978 |
Echinococcus granulosus | GPCR family 2 | 0.0067 | 0.0344 | 0.0499 |
Schistosoma mansoni | rab6-interacting | 0.014 | 0.1057 | 0.1049 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0084 | 0.0504 | 0.0739 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1108 | 0.234 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0042 | 0.0096 | 0.0203 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0117 | 0.0969 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0061 | 0.0278 | 1 |
Schistosoma mansoni | single-minded | 0.0057 | 0.0246 | 0.0236 |
Brugia malayi | hypothetical protein | 0.022 | 0.1838 | 0.3868 |
Echinococcus granulosus | geminin | 0.0188 | 0.1529 | 0.227 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0081 | 0.0477 | 0.0468 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0177 | 0.1422 | 0.3001 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0019 | 0.004 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0177 | 0.1422 | 0.1413 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.0402 | 0.0393 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0094 | 0.0602 | 0.1254 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0177 | 0.1422 | 0.2988 |
Echinococcus multilocularis | GPCR, family 2 | 0.0067 | 0.0344 | 0.0499 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0042 | 0.01 | 0.0135 |
Schistosoma mansoni | lipoxygenase | 0.0716 | 0.6704 | 0.6701 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0094 | 0.0602 | 0.0593 |
Schistosoma mansoni | polycystin 1-related | 0.014 | 0.1057 | 0.1049 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0177 | 0.1422 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0067 | 0.0344 | 0.0707 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0094 | 0.0602 | 0.0886 |
Brugia malayi | hypothetical protein | 0.0094 | 0.0602 | 0.1254 |
Brugia malayi | Cytochrome P450 family protein | 0.0042 | 0.0096 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0087 | 0.0183 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0177 | 0.1422 | 0.3001 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | thyroid hormone receptor | 0.0177 | 0.1422 | 0.1413 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.042 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0042 | 0.0096 | 0.0203 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.041 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0177 | 0.1422 | 0.2109 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0177 | 0.1422 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.041 | 0.0599 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0177 | 0.1422 | 0.2988 |
Mycobacterium ulcerans | putative regulatory protein | 0.0042 | 0.01 | 0.1935 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0177 | 0.1422 | 0.3001 |
Echinococcus granulosus | tar DNA binding protein | 0.0133 | 0.0986 | 0.1459 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 0.5 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0117 | 0.0638 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0177 | 0.1422 | 0.2988 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 0.0698 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0109 | 0.0759 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0296 | 0.2587 | 0.385 |
Brugia malayi | tailless protein | 0.0084 | 0.0504 | 0.1047 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Onchocerca volvulus | 0.0057 | 0.0241 | 0.131 | |
Echinococcus granulosus | jun protein | 0.028 | 0.2427 | 0.3611 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0177 | 0.1422 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Schistosoma mansoni | rab6-interacting | 0.014 | 0.1057 | 0.1049 |
Schistosoma mansoni | zinc finger protein | 0.0084 | 0.0504 | 0.0495 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0177 | 0.1422 | 0.2109 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0084 | 0.0504 | 0.1047 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0059 | 0.0263 | 0.6168 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0759 | 0.1602 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Echinococcus granulosus | death domain containing protein | 0.0034 | 0.0016 | 0.001 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.014 | 0.1057 | 0.1565 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.042 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.0212 | 0.0303 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.014 | 0.1057 | 0.1565 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0109 | 0.0759 | 0.075 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.042 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0177 | 0.1422 | 0.2109 |
Schistosoma mansoni | lipoxygenase | 0.0464 | 0.4234 | 0.4229 |
Echinococcus multilocularis | RUN | 0.014 | 0.1057 | 0.1565 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0212 | 0.1767 | 0.3719 |
Brugia malayi | Heterochromatin protein 1 | 0.0073 | 0.0402 | 0.083 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0091 | 0.0579 | 0.1205 |
Loa Loa (eye worm) | RNA binding protein | 0.0133 | 0.0986 | 0.2083 |
Onchocerca volvulus | 0.0084 | 0.0504 | 0.2743 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.042 | 1 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0579 | 0.1223 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0109 | 0.0759 | 0.1602 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0042 | 0.0096 | 0.2116 |
Brugia malayi | nuclear hormone receptor | 0.0177 | 0.1422 | 0.2988 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0081 | 0.0477 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0084 | 0.0504 | 0.1064 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0986 | 0.0978 |
Brugia malayi | nuclear receptor NHR-67 | 0.0084 | 0.0504 | 0.1047 |
Plasmodium falciparum | LCCL domain-containing protein | 0.014 | 0.1057 | 1 |
Onchocerca volvulus | 0.0177 | 0.1422 | 0.7735 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0133 | 0.0986 | 0.2083 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.2352 | 0.4965 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0133 | 0.0986 | 0.2083 |
Loa Loa (eye worm) | DR-78 | 0.0084 | 0.0504 | 0.1064 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.0204 | 0.4162 |
Brugia malayi | hypothetical protein | 0.0094 | 0.0602 | 0.1254 |
Echinococcus granulosus | FTZ F1 alpha | 0.0177 | 0.1422 | 0.2109 |
Brugia malayi | nuclear receptor RXR | 0.0094 | 0.0602 | 0.1254 |
Schistosoma mansoni | nuclear hormone receptor | 0.0177 | 0.1422 | 0.1413 |
Brugia malayi | ecdysteroid receptor | 0.0177 | 0.1422 | 0.2988 |
Brugia malayi | bZIP transcription factor family protein | 0.028 | 0.2427 | 0.5114 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0094 | 0.0602 | 0.0886 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0177 | 0.1422 | 0.1413 |
Schistosoma mansoni | jun-related protein | 0.0227 | 0.1913 | 0.1905 |
Brugia malayi | TAR-binding protein | 0.0133 | 0.0986 | 0.2067 |
Schistosoma mansoni | netrin receptor unc5 | 0.0034 | 0.0016 | 0.0007 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0173 | 0.1382 | 0.205 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.014 | 0.1057 | 0.1565 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0084 | 0.0504 | 0.0495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0986 | 0.0978 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0067 | 0.0344 | 0.0726 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0109 | 0.0759 | 0.1585 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0177 | 0.1422 | 0.2988 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0212 | 0.1767 | 0.3731 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0177 | 0.1422 | 0.2988 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 1 |
Echinococcus granulosus | single minded 2 | 0.0042 | 0.01 | 0.0135 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.0477 | 0.099 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0034 | 0.0016 | 0.001 |
Brugia malayi | Cytochrome P450 family protein | 0.0042 | 0.0096 | 0.0184 |
Brugia malayi | nuclear hormone receptor | 0.0084 | 0.0504 | 0.1047 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0042 | 0.0096 | 0.2116 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0094 | 0.0602 | 0.0593 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0073 | 0.0402 | 0.0849 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0084 | 0.0504 | 0.1047 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Loa Loa (eye worm) | serotonin transporter b | 0.0109 | 0.0759 | 0.1602 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.0278 | 0.5754 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0061 | 0.0278 | 0.6548 |
Onchocerca volvulus | 0.0091 | 0.0579 | 0.3151 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0145 | 0.1108 | 0.2325 |
Schistosoma mansoni | hypothetical protein | 0.0145 | 0.1108 | 0.11 |
Onchocerca volvulus | 0.0042 | 0.01 | 0.0543 | |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0016 | 0.0007 |
Schistosoma mansoni | tyrosinase precursor | 0.0091 | 0.0579 | 0.057 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0084 | 0.0504 | 0.0739 |
Brugia malayi | RNA binding protein | 0.0133 | 0.0986 | 0.2067 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1057 | 0.2232 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0177 | 0.1422 | 0.1413 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0241 | 0.0232 |
Brugia malayi | Probable ClpP-like protease | 0.0081 | 0.0477 | 0.0988 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.028 | 0.2427 | 0.3611 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0084 | 0.0504 | 0.2743 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0084 | 0.0504 | 0.0495 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0344 | 0.0335 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0177 | 0.1422 | 0.1413 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.041 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0177 | 0.1422 | 0.2988 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 0.0698 |
Trypanosoma brucei | cytochrome P450, putative | 0.0042 | 0.0096 | 0.2116 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0602 | 0.1272 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0759 | 0.1602 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.0202 | 0.0426 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.0212 | 0.0429 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0084 | 0.0504 | 0.1064 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.0204 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0515 | 0.4736 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0716 | 0.6704 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0042 | 0.0096 | 0.2116 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0177 | 0.1422 | 0.2988 |
Schistosoma mansoni | loxhd1 | 0.014 | 0.1057 | 0.1049 |
Onchocerca volvulus | 0.0091 | 0.0579 | 0.3151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0477 | 0.1006 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0177 | 0.1422 | 0.2109 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0212 | 0.0203 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.0477 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.0402 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0087 | 0.0472 |
Brugia malayi | hypothetical protein | 0.014 | 0.1057 | 0.2216 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.0402 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.241 | 0.5088 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0084 | 0.0504 | 0.1047 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0042 | 0.0096 | 0.1859 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.0212 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Brugia malayi | conserved hypotetical protein | 0.0084 | 0.0504 | 0.1047 |
Brugia malayi | hypothetical protein | 0.014 | 0.1057 | 0.2216 |
Schistosoma mansoni | hypothetical protein | 0.0227 | 0.1913 | 0.1905 |
Onchocerca volvulus | 0.0109 | 0.0759 | 0.4129 | |
Onchocerca volvulus | Netrin receptor homolog | 0.0034 | 0.0016 | 0.0089 |
Schistosoma mansoni | nuclear receptor | 0.0084 | 0.0504 | 0.0495 |
Brugia malayi | steroid hormone receptor | 0.0177 | 0.1422 | 0.2988 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0091 | 0.0579 | 0.1205 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0177 | 0.1422 | 0.2109 |
Echinococcus granulosus | RUN | 0.014 | 0.1057 | 0.1565 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.014 | 0.1057 | 0.1565 |
Brugia malayi | Cytochrome P450 family protein | 0.0154 | 0.1196 | 0.2511 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0177 | 0.1422 | 0.1413 |
Brugia malayi | Uncoordinated protein 44 | 0.0034 | 0.0016 | 0.0014 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0034 | 0.0016 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0303 | 0.2659 | 0.2652 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0091 | 0.0579 | 0.1223 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0117 | 0.0969 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0084 | 0.0504 | 0.0739 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0504 | 0.1047 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0084 | 0.0504 | 0.0739 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0177 | 0.1422 | 0.2109 |
Brugia malayi | ShTK domain containing protein | 0.0091 | 0.0579 | 0.1205 |
Brugia malayi | hypothetical protein | 0.0278 | 0.241 | 0.5078 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0016 | 0.0034 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0177 | 0.1422 | 0.2109 |
Brugia malayi | PAS domain containing protein | 0.0057 | 0.0246 | 0.0499 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0177 | 0.1422 | 0.2988 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.041 | 0.0401 |
Echinococcus multilocularis | geminin | 0.0188 | 0.1529 | 0.227 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0177 | 0.142 | 0.2998 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0081 | 0.0477 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0075 | 0.042 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0344 | 0.0335 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.1057 | 0.1049 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0278 | 0.241 | 0.3585 |
Brugia malayi | nuclear receptor RXR | 0.0084 | 0.0504 | 0.1047 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0057 | 0.0241 | 0.0489 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0177 | 0.1422 | 0.2988 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0034 | 0.0016 | 0.001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0177 | 0.1422 | 0.3001 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0177 | 0.1422 | 0.1413 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0094 | 0.0602 | 0.1254 |
Brugia malayi | ecdysone receptor | 0.0084 | 0.0504 | 0.1047 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0084 | 0.0504 | 0.0739 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0602 | 0.1272 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.0204 | 0.7233 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.0278 | 0.5754 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0344 | 0.0499 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0084 | 0.0504 | 0.0739 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0177 | 0.1422 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0344 | 0.0726 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0177 | 0.1422 | 0.2109 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0094 | 0.0602 | 0.1272 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0084 | 0.0504 | 0.2743 |
Brugia malayi | Doublecortin family protein | 0.014 | 0.1057 | 0.2216 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0177 | 0.1422 | 0.2988 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0034 | 0.0016 | 0.0034 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0084 | 0.0504 | 0.0739 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0177 | 0.1422 | 0.3001 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1057 | 0.2232 |
Echinococcus multilocularis | tar DNA binding protein | 0.0133 | 0.0986 | 0.1459 |
Onchocerca volvulus | 0.022 | 0.1838 | 1 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0177 | 0.1422 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0579 | 0.1223 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.014 | 0.1057 | 0.1565 |
Schistosoma mansoni | serine-type protease inhibitor | 0.1052 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0177 | 0.1422 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0602 | 0.1272 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0177 | 0.1422 | 0.1413 |
Echinococcus multilocularis | Ankyrin | 0.0034 | 0.0019 | 0.0014 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.041 | 0.0401 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0087 | 0.0164 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0177 | 0.1422 | 0.2988 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0504 | 0.1047 |
Schistosoma mansoni | tyrosinase precursor | 0.0091 | 0.0579 | 0.057 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0177 | 0.1422 | 0.2109 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.0402 | 0.0586 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0067 | 0.0344 | 0.0707 |
Brugia malayi | hypothetical protein | 0.0074 | 0.041 | 0.0848 |
Onchocerca volvulus | 0.0084 | 0.0504 | 0.2743 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0177 | 0.1422 | 0.7735 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0177 | 0.1422 | 0.2988 |
Brugia malayi | follicle stimulating hormone receptor | 0.0234 | 0.1981 | 0.4172 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.041 | 0.5 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.0204 | 0.7233 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0759 | 0.1602 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0173 | 0.1382 | 0.205 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0084 | 0.0504 | 0.0739 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0504 | 0.1064 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0091 | 0.0579 | 0.1205 |
Echinococcus multilocularis | serotonin transporter | 0.0109 | 0.0759 | 0.1119 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.042 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0091 | 0.0579 | 0.1223 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 23 uM | Inhibition of high affinity uptake of [3H]-dopamine into striatal nerve endings (synaptosomes) | ChEMBL. | 10406650 |
Ki (binding) | = 23 uM | Inhibition of high affinity uptake of [3H]-dopamine into striatal nerve endings (synaptosomes) | ChEMBL. | 10406650 |
Ki (binding) | = 34 uM | Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | ChEMBL. | 10406650 |
Ki (binding) | = 34 uM | Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | ChEMBL. | 10406650 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.