Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable reductase | 0.0382 | 0.706 | 0.8958 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0105 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0019 | 0.0045 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0382 | 0.706 | 0.8958 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 0.0176 | 0.0536 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0176 | 0.0157 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.012 | 0.2018 | 0.2543 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0105 | 0.0242 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Onchocerca volvulus | Huntingtin homolog | 0.0241 | 0.4353 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0031 | 0.0019 |
Schistosoma mansoni | lamin | 0.0027 | 0.024 | 0.0221 |
Onchocerca volvulus | 0.0047 | 0.0625 | 0.1397 | |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0058 | 0.0838 | 0.134 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1491 | 0.4494 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0105 | 0.0086 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0382 | 0.706 | 0.8958 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0105 | 0.0086 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0493 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0031 | 0.0071 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.024 | 0.055 |
Treponema pallidum | NADH oxidase | 0.0058 | 0.0838 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0105 | 0.0086 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.1431 | 0.1415 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0105 | 0.0141 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0235 | 0.4235 | 0.9729 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0186 | 0.3293 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0031 | 0.0012 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0105 | 0.0242 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0176 | 0.0478 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.1431 | 0.2312 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0105 | 0.0141 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.012 | 0.2018 | 0.2003 |
Brugia malayi | hypothetical protein | 0.023 | 0.4141 | 0.9513 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0043 | 0.0542 | 0.1246 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0321 | 0.092 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0234 | 0.4213 | 0.9678 |
Echinococcus multilocularis | smad | 0.0016 | 0.0031 | 0.0019 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0105 | 0.0242 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0382 | 0.706 | 0.8958 |
Brugia malayi | glutamate synthase | 0.0015 | 0.0019 | 0.0045 |
Toxoplasma gondii | thioredoxin reductase | 0.0168 | 0.294 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0058 | 0.0838 | 0.4096 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0382 | 0.706 | 0.8958 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.1431 | 0.3288 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.4141 | 0.9513 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0425 | 0.7879 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.1431 | 0.3288 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0058 | 0.0838 | 0.2803 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.012 | 0.2018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.4353 | 1 |
Echinococcus granulosus | geminin | 0.0334 | 0.6127 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0074 | 0.0188 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0074 | 0.009 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.6127 | 0.6119 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0031 | 0.0012 |
Brugia malayi | glutathione reductase | 0.0168 | 0.294 | 0.6753 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0176 | 0.0478 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0074 | 0.0168 |
Schistosoma mansoni | smad | 0.0016 | 0.0031 | 0.0012 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0105 | 0.0141 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0031 | 0.0019 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0186 | 0.3293 | 0.7554 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.4141 | 0.6749 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0058 | 0.0838 | 0.2501 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0186 | 0.3293 | 0.7565 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0105 | 0.0141 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.012 | 0.2018 | 0.6844 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.1431 | 0.2312 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0025 | 0.001 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0025 | 0.0058 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0074 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | kinase | 0.0095 | 0.1538 | 0.1521 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0736 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0321 | 0.092 |
Onchocerca volvulus | 0.002 | 0.0105 | 0.0199 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.6127 | 0.6119 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0382 | 0.706 | 0.8958 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0677 | 0.1556 |
Echinococcus granulosus | lamin | 0.0027 | 0.024 | 0.0361 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0074 | 0.0168 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0168 | 0.294 | 0.3716 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0074 | 0.0168 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0105 | 0.0199 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0074 | 0.0188 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0186 | 0.3293 | 0.536 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0025 | 0.0058 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0176 | 0.0256 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0493 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0058 | 0.0838 | 0.082 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0105 | 0.0141 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0186 | 0.3293 | 0.536 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0074 | 0.007 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0412 | 0.0643 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0105 | 0.0141 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.024 | 0.0361 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0074 | 0.0168 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0412 | 0.0393 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0412 | 0.1199 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.1431 | 0.2312 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0105 | 0.0242 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0105 | 0.0141 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | hypothetical protein | 0.0241 | 0.4353 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0015 | 0.0019 | 0.0045 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0105 | 0.0086 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0.0321 | 0.092 |
Onchocerca volvulus | Huntingtin homolog | 0.0241 | 0.4353 | 1 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0058 | 0.0838 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0074 | 0.0672 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0058 | 0.0838 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0074 | 0.0168 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0058 | 0.0838 | 0.2803 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0058 | 0.0838 | 0.2803 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0074 | 0.0672 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0.0321 | 0.092 |
Brugia malayi | Smad1 | 0.0016 | 0.0031 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.024 | 0.055 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.024 | 0.055 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0425 | 0.7879 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.023 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0677 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.1431 | 0.1415 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.012 | 0.2018 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0074 | 0.009 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0058 | 0.0838 | 0.2501 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.024 | 0.0361 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.1431 | 0.2312 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0031 | 0.0019 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1491 | 0.4494 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0031 | 0.0071 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0105 | 0.0141 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0321 | 0.0493 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0412 | 0.0393 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0006 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0031 | 0.0019 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0015 | 0.0019 | 0.0045 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0186 | 0.3293 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0058 | 0.0838 | 0.1042 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0736 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0025 | 0.0058 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0074 | 0.0171 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0031 | 0.0019 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0025 | 0.001 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0412 | 0.0643 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0031 | 0.0012 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0.0176 | 0.0478 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0382 | 0.706 | 0.8958 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0425 | 0.7879 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0105 | 0.0086 |
Plasmodium falciparum | thioredoxin reductase | 0.0058 | 0.0838 | 0.2803 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0105 | 0.0086 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0058 | 0.0838 | 0.2501 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0058 | 0.0838 | 0.2501 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0176 | 0.0157 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0074 | 0.0171 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.012 | 0.2018 | 0.2003 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0105 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0105 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0006 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0168 | 0.294 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.024 | 0.055 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0321 | 0.092 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0105 | 0.0141 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0105 | 0.0086 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0058 | 0.0838 | 0.4096 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0058 | 0.0838 | 0.2501 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0.0176 | 0.0536 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0015 | 0.0019 | 0.0045 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0105 | 0.0086 |
Brugia malayi | MH2 domain containing protein | 0.0235 | 0.4235 | 0.9729 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0302 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0412 | 0.0946 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0105 | 0.0086 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Leishmania major | trypanothione reductase | 0.0168 | 0.294 | 0.8921 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0176 | 0.0404 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0025 | 0.001 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.1031 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0025 | 0.001 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0176 | 0.0157 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0031 | 0.0071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0105 | 0.0242 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0074 | 0.0168 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0074 | 0.0055 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0186 | 0.3293 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0105 | 0.0242 |
Loa Loa (eye worm) | glutathione reductase | 0.0168 | 0.294 | 0.6753 |
Echinococcus granulosus | smad | 0.0016 | 0.0031 | 0.0019 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.1031 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0168 | 0.294 | 0.6753 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0105 | 0.0086 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0736 |
Plasmodium falciparum | glutathione reductase | 0.0168 | 0.294 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0186 | 0.3293 | 0.328 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0105 | 0.0242 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0105 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0376 | 0.0863 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0058 | 0.0838 | 0.1925 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0058 | 0.0838 | 0.4096 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0493 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0105 | 0.0141 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.024 | 0.0221 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.4141 | 0.6749 |
Plasmodium falciparum | thioredoxin reductase | 0.0168 | 0.294 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.1431 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.4353 | 1 |
Onchocerca volvulus | 0.0027 | 0.024 | 0.0508 | |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.012 | 0.2018 | 0.6105 |
Schistosoma mansoni | lamin | 0.0027 | 0.024 | 0.0221 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0105 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0105 | 0.0242 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0.0321 | 0.1031 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 0.0176 | 0.0478 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0677 | 0.1556 |
Plasmodium falciparum | glutathione reductase | 0.0058 | 0.0838 | 0.2803 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0376 | 0.0357 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0321 | 0.0493 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0105 | 0.0242 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0058 | 0.0838 | 0.2501 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0031 | 0.0321 | 0.0383 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0105 | 0.0199 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0074 | 0.0275 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0176 | 0.0404 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0105 | 0.0141 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0176 | 0.0404 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.024 | 0.0361 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0105 | 0.0141 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0176 | 0.0478 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0031 | 0.0071 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0058 | 0.0838 | 0.2803 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0031 | 0.0019 |
Trypanosoma brucei | trypanothione reductase | 0.0168 | 0.294 | 0.8921 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0058 | 0.0838 | 0.2501 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0025 | 0.0058 |
Giardia lamblia | Kinase, PLK | 0.0186 | 0.3293 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0031 | 0.0071 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0031 | 0.0012 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0105 | 0.0242 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.012 | 0.2018 | 0.3273 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0677 | 0.1556 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0176 | 0.0478 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0425 | 0.7879 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Trypanosoma brucei | polo-like protein kinase | 0.0186 | 0.3293 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0625 | 0.0606 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0376 | 0.0863 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0186 | 0.3293 | 0.7565 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.012 | 0.2018 | 0.3273 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.012 | 0.2018 | 1 |
Echinococcus multilocularis | lamin | 0.0027 | 0.024 | 0.0361 |
Echinococcus multilocularis | musashi | 0.0027 | 0.024 | 0.0361 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0105 | 0.0242 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0025 | 0.001 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0105 | 0.0141 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0058 | 0.0838 | 0.2501 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0412 | 0.1199 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0105 | 0.0242 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0058 | 0.0838 | 0.2501 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.024 | 0.055 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0105 | 0.0141 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0058 | 0.0838 | 0.2803 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0058 | 0.0838 | 0.2501 |
Plasmodium vivax | glutathione reductase, putative | 0.0168 | 0.294 | 1 |
Onchocerca volvulus | 0.0027 | 0.024 | 0.0508 | |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0031 | 0.0071 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0031 | 0.0012 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0105 | 0.0242 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0074 | 0.0168 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0186 | 0.3293 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0058 | 0.0838 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0105 | 0.0199 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0015 | 0.0019 | 0.0045 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0105 | 0.0242 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0074 | 0.0055 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0625 | 0.1435 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0025 | 0.001 |
Onchocerca volvulus | 0.0234 | 0.4213 | 0.9677 | |
Echinococcus multilocularis | geminin | 0.0334 | 0.6127 | 1 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0.0176 | 0.0478 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0074 | 0.0168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0105 | 0.0242 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0058 | 0.0838 | 0.134 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0625 | 0.0606 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0176 | 0.0256 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0058 | 0.0838 | 0.2803 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0043 | 0.0542 | 0.1246 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0168 | 0.294 | 0.8921 |
Brugia malayi | Thioredoxin reductase | 0.0168 | 0.294 | 0.6753 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0015 | 0.0019 | 0.0045 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0169 | 0.2959 | 0.4813 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0105 | 0.0242 |
Brugia malayi | Pax transcription factor protein 2 | 0.0234 | 0.4213 | 0.9678 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0058 | 0.0838 | 0.2501 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0176 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0105 | 0.0242 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0031 | 0.0071 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0412 | 0.1199 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0025 | 0.0006 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0235 | 0.4235 | 0.9729 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0.0321 | 0.1031 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0105 | 0.0141 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0169 | 0.2959 | 0.4813 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0105 | 0.0141 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0412 | 0.1199 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0105 | 0.0141 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0186 | 0.3293 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.