Detailed information for compound 771738

Basic information

Technical information
  • TDR Targets ID: 771738
  • Name: 2-furan-2-yl-1-(2-methylprop-2-enyl)benzimida zole
  • MW: 238.284 | Formula: C15H14N2O
  • H donors: 0 H acceptors: 1 LogP: 3.57 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=C)Cn1c(nc2c1cccc2)c1ccco1
  • InChi: 1S/C15H14N2O/c1-11(2)10-17-13-7-4-3-6-12(13)16-15(17)14-8-5-9-18-14/h3-9H,1,10H2,2H3
  • InChiKey: IKQZFIHSWZGFFM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(2-furyl)-1-(2-methylprop-2-enyl)benzimidazole
  • IDI1_010563
  • BAS 04881178
  • STOCK2S-61206
  • IFLab1_004808
  • 2-Furan-2-yl-1-(2-methyl-allyl)-1H-benzoimidazole
  • ZINC00203378

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0262 0.2828 0.5777
Brugia malayi Calcitonin receptor-like protein seb-1 0.0439 0.4857 1
Echinococcus granulosus GPCR family 2 0.0139 0.1429 0.1644
Leishmania major hypothetical protein, conserved 0.0041 0.0308 0.2824
Brugia malayi Protein kinase domain containing protein 0.0066 0.0598 0.1231
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0057 0.0044
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0139 0.1429 0.1644
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0057 0.0074
Schistosoma mansoni hypothetical protein 0.0752 0.8421 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0139 0.1429 0.1383
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0308 0.084
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0598 0.1798
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0213 0.0191
Mycobacterium ulcerans glutaminase 0.0284 0.3084 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0213 0.0191
Onchocerca volvulus 0.0041 0.0308 0.037
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0057 0.0074
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0053 0.0109
Schistosoma mansoni hypothetical protein 0.0139 0.1429 0.1644
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0124 0.1255 0.4351
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0097 0.0955 1
Giardia lamblia Kinase, CMGC CLK 0.0066 0.0598 1
Loa Loa (eye worm) glutaminase 0.0284 0.3084 0.631
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0308 0.0634
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0057 0.0074
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2828 0.3317
Brugia malayi RNA recognition motif domain containing protein 0.0262 0.2828 0.5823
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Brugia malayi beta-lactamase family protein 0.0041 0.0308 0.0634
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0057 0.0044
Plasmodium falciparum glutathione reductase 0.0019 0.0057 0.0074
Toxoplasma gondii thioredoxin reductase 0.0054 0.0462 0.7497
Schistosoma mansoni hypothetical protein 0.0139 0.1429 0.1644
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0057 0.0015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0057 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0139 0.1429 0.2942
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0308 0.053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0057 0.0044
Schistosoma mansoni glutaminase 0.0284 0.3084 0.3622
Onchocerca volvulus 0.0041 0.0308 0.037
Echinococcus multilocularis 0.0065 0.0587 0.0536
Brugia malayi TAR-binding protein 0.0262 0.2828 0.5823
Loa Loa (eye worm) hypothetical protein 0.0096 0.0943 0.1854
Trypanosoma brucei trypanothione reductase 0.0054 0.0462 0.453
Entamoeba histolytica hypothetical protein 0.0097 0.0955 1
Brugia malayi latrophilin 2 splice variant baaae 0.03 0.327 0.6733
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0213 0.0191
Entamoeba histolytica protein kinase, putative 0.0097 0.0955 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0057 0.0074
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.2032 0.1989
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0138 0.1412 0.4922
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.2032 0.2365
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0057 0.0117
Mycobacterium tuberculosis Probable reductase 0.0124 0.1255 0.4351
Plasmodium falciparum protein serine/threonine kinase-1 0.0066 0.0598 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0124 0.1255 0.4351
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.2032 0.2365
Echinococcus multilocularis dual specificity protein kinase clk2 0.0066 0.0598 0.0548
Loa Loa (eye worm) hypothetical protein 0.0096 0.0943 0.1854
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0097 0.0955 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0066 0.0598 0.6043
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0057 0.0013
Schistosoma mansoni hypothetical protein 0.03 0.327 0.3845
Echinococcus multilocularis geminin 0.0752 0.8421 0.8412
Schistosoma mansoni hypothetical protein 0.0139 0.1429 0.1644
Brugia malayi Latrophilin receptor protein 2 0.0139 0.1429 0.2942
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0019 0.0057 0.5
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0308 0.084
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.032 0.0319
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2828 0.3317
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0066 0.0598 0.1135
Loa Loa (eye worm) hypothetical protein 0.0439 0.4857 1
Mycobacterium ulcerans lipase LipD 0.0041 0.0308 0.084
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0151 0.1792
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0213 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0955 0.1078
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0598 0.0651
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0308 0.084
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0308 0.0922
Plasmodium falciparum thioredoxin reductase 0.0019 0.0057 0.0074
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0066 0.0598 0.6043
Entamoeba histolytica hypothetical protein 0.0042 0.032 0.2957
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0308 0.0922
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0598 0.0651
Mycobacterium tuberculosis Conserved protein 0.0041 0.0308 0.0922
Mycobacterium tuberculosis Probable dehydrogenase 0.0124 0.1255 0.4351
Leishmania major trypanothione reductase 0.0054 0.0462 0.453
Toxoplasma gondii ABC1 family protein 0.0041 0.0308 0.4674
Brugia malayi Pre-SET motif family protein 0.0226 0.2423 0.499
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0057 0.0044
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0066 0.0598 0.6043
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0097 0.0955 1
Onchocerca volvulus 0.0041 0.0308 0.037
Schistosoma mansoni hypothetical protein 0.0042 0.032 0.0319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.2032 0.2365
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0139 0.1429 0.1383
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0308 0.2824
Loa Loa (eye worm) hypothetical protein 0.0027 0.0151 0.0203
Loa Loa (eye worm) hypothetical protein 0.0139 0.1429 0.2864
Plasmodium vivax serine/threonine kinase-1, putative 0.0066 0.0598 1
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0066 0.0598 1
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0308 0.0922
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2828 0.3317
Loa Loa (eye worm) hypothetical protein 0.03 0.327 0.6697
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0057 0.0074
Echinococcus granulosus hypothetical protein 0.0065 0.0587 0.0638
Mycobacterium ulcerans hypothetical protein 0.0041 0.0308 0.084
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0151 0.1083
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0097 0.0955 0.1878
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0151 0.1792
Loa Loa (eye worm) TAR-binding protein 0.0262 0.2828 0.5777
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0308 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2828 0.3317
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Treponema pallidum NADH oxidase 0.0019 0.0057 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0139 0.1429 0.2864
Echinococcus multilocularis GPCR, family 2 0.0139 0.1429 0.1383
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0057 0.0044
Echinococcus multilocularis dual specificity 0.0097 0.0955 0.0907
Echinococcus granulosus dual specificity protein kinase clk2 0.0066 0.0598 0.0651
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0439 0.4857 1
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0057 0.0044
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0308 0.0922
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0151 0.1083
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0199 0.0175
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Loa Loa (eye worm) glutaminase 2 0.0284 0.3084 0.631
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0308 0.2824
Leishmania major protein kinase, putative 0.0066 0.0598 0.6043
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.0462 0.0488
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0066 0.0598 0.6043
Onchocerca volvulus 0.0257 0.278 1
Brugia malayi hypothetical protein 0.0027 0.0151 0.031
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0308 0.084
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0308 0.4674
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0151 0.1083
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0057 0.0005
Echinococcus granulosus dual specificity 0.0097 0.0955 0.1078
Loa Loa (eye worm) glutathione reductase 0.0054 0.0462 0.0851
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0057 0.0074
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0057 0.0013
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0057 0.0044
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0439 0.4857 1
Loa Loa (eye worm) RNA binding protein 0.0262 0.2828 0.5777
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.2032 0.4119
Brugia malayi glutaminase DH11.1 0.0284 0.3084 0.635
Brugia malayi beta-lactamase 0.0041 0.0308 0.0634
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.2032 0.2365
Trichomonas vaginalis set domain proteins, putative 0.0257 0.278 0.8997
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0151 0.1792
Entamoeba histolytica hypothetical protein 0.0042 0.032 0.2957
Entamoeba histolytica hypothetical protein 0.0042 0.032 0.2957
Loa Loa (eye worm) beta-lactamase 0.0041 0.0308 0.053
Brugia malayi hypothetical protein 0.0042 0.032 0.0658
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0462 0.0851
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2828 0.3317
Brugia malayi Protein kinase domain containing protein 0.0097 0.0955 0.1966
Mycobacterium tuberculosis Probable oxidoreductase 0.0138 0.1412 0.4922
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0097 0.0955 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.032 0.0268
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0138 0.1412 1
Trichomonas vaginalis glutaminase, putative 0.0284 0.3084 1
Brugia malayi beta-lactamase family protein 0.0041 0.0308 0.0634
Brugia malayi Pre-SET motif family protein 0.0032 0.0213 0.0438
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0308 0.2824
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0213 0.2929
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.2032 0.2365
Plasmodium vivax SET domain protein, putative 0.0032 0.0213 0.2929
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0124 0.1255 0.4351
Mycobacterium tuberculosis Conserved protein 0.0041 0.0308 0.0922
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.032 0.0319
Echinococcus granulosus geminin 0.0752 0.8421 1
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0308 0.0922
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0124 0.1255 0.4351
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0308 0.084
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0308 0.0304
Loa Loa (eye worm) hypothetical protein 0.0065 0.0587 0.1111
Leishmania major protein kinase, putative 0.0066 0.0598 0.6043
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0139 0.1429 0.1644
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0213 0.016
Echinococcus multilocularis tar DNA binding protein 0.0262 0.2828 0.279
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0066 0.0598 0.6043
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0213 0.016
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0057 0.0074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0057 0.0013
Entamoeba histolytica protein kinase, putative 0.0097 0.0955 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0066 0.0598 0.6043
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.2423 0.4934
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0308 0.0922
Brugia malayi Thioredoxin reductase 0.0054 0.0462 0.095
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0308 0.0922
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.0462 0.0411
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Leishmania major hypothetical protein, conserved 0.0027 0.0151 0.1083
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0057 0.0004
Plasmodium falciparum glutathione reductase 0.0054 0.0462 0.7497
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0138 0.1412 0.4922
Entamoeba histolytica protein kinase domain containing protein 0.0097 0.0955 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0057 0.0044
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0124 0.1255 0.8573
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0308 0.084
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0308 0.0256
Mycobacterium ulcerans beta-lactamase 0.0041 0.0308 0.084
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0151 0.1792
Brugia malayi RNA binding protein 0.0262 0.2828 0.5823
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0261 0.2815 1
Trichomonas vaginalis esterase, putative 0.0041 0.0308 0.084
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0308 0.0304
Loa Loa (eye worm) hypothetical protein 0.0032 0.0213 0.0332
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.2032 0.4184
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0462 0.7497
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0057 1
Plasmodium falciparum thioredoxin reductase 0.0054 0.0462 0.7497
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0057 0.0044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0057 0.0005
Plasmodium vivax glutathione reductase, putative 0.0054 0.0462 0.7497
Mycobacterium tuberculosis Conserved protein 0.0041 0.0308 0.0922
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0462 0.453
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0308 0.084
Schistosoma mansoni hypothetical protein 0.0139 0.1429 0.1644
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0462 0.1479
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0057 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0213 0.0191
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.2032 0.1989
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0057 0.0044
Echinococcus granulosus tar DNA binding protein 0.0262 0.2828 0.3317
Brugia malayi hypothetical protein 0.0017 0.0041 0.0085
Brugia malayi glutathione reductase 0.0054 0.0462 0.095
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0057 0.0013
Schistosoma mansoni hypothetical protein 0.0752 0.8421 1
Entamoeba histolytica hypothetical protein 0.0042 0.032 0.2957

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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