Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Plasmodium falciparum | zinc finger protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.879 | 0.876 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.879 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.879 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.879 | 0.876 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.02 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0003 | 0 | 0.5 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.879 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.02 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3602 | 0.3602 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.02 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.879 | 0.876 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.3602 | 0.3852 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.02 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.02 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0352 | 0.0115 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0047 | 0.0047 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.3685 | 0.3685 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1727 | 0.1727 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.3602 | 0.3852 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.1727 | 0.1524 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.3602 | 0.3852 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1622 | 0.1622 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3602 | 0.3602 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3602 | 0.3602 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1727 | 0.1727 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.02 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.3602 | 0.3445 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.3602 | 0.3857 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.1727 | 0.1524 |
Onchocerca volvulus | 0.003 | 0.1622 | 0.5 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.3602 | 0.3445 |
Brugia malayi | RNA binding protein | 0.0061 | 0.3602 | 0.3857 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.02 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3602 | 0.3602 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.02 | 1 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.3602 | 0.3857 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.1622 | 0.1513 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.1622 | 0.1506 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3602 | 0.3602 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0352 | 0.0115 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.3268 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.02 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.02 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.