Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.2204 | 0.1658 |
Echinococcus granulosus | chromobox protein 1 | 0.0084 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0084 | 1 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0054 | 0.538 | 0.538 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.2204 | 0.1658 |
Schistosoma mansoni | chromobox protein | 0.0084 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.538 | 0.538 |
Leishmania major | DNA polymerase eta, putative | 0.0038 | 0.2911 | 0.4775 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.6323 | 0.6323 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0023 | 0.0654 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0051 | 0.487 | 0.4511 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0023 | 0.0654 | 0.0654 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.4319 | 0.4319 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0023 | 0.0654 | 0.0654 |
Echinococcus multilocularis | dna polymerase kappa | 0.0023 | 0.0654 | 0.0654 |
Trichomonas vaginalis | chromobox protein, putative | 0.0051 | 0.487 | 0.4511 |
Echinococcus granulosus | dna polymerase eta | 0.0054 | 0.538 | 0.538 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.4319 | 0.7399 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3396 | 0.3396 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0023 | 0.0654 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0054 | 0.538 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.2754 | 0.2754 |
Schistosoma mansoni | chromobox protein | 0.0084 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0038 | 0.2911 | 0.4775 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.6323 | 0.6323 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0023 | 0.0654 | 0.0654 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.3396 | 0.3396 |
Schistosoma mansoni | DNA polymerase eta | 0.0054 | 0.538 | 0.538 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0023 | 0.0654 | 0.0654 |
Leishmania major | DNA polymerase eta, putative | 0.0054 | 0.538 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.3396 | 0.3396 |
Echinococcus granulosus | dna polymerase kappa | 0.0023 | 0.0654 | 0.0654 |
Echinococcus multilocularis | chromobox protein 1 | 0.0084 | 1 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0038 | 0.2911 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0023 | 0.0654 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.6323 | 0.6323 |
Echinococcus granulosus | chromobox protein 1 | 0.0084 | 1 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0023 | 0.0654 | 0.5 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0084 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0023 | 0.0654 | 0.0654 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0054 | 0.538 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0084 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0023 | 0.0654 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.4319 | 0.3922 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.6323 | 0.6323 |
Brugia malayi | chromobox protein homolog 3 | 0.0047 | 0.4319 | 0.4319 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0054 | 0.538 | 0.538 |
Echinococcus multilocularis | chromobox protein 1 | 0.0084 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0023 | 0.0654 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.4319 | 0.3922 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0051 | 0.487 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.