Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1278 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0067 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.1278 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0 | 0.5 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.1278 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.1278 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1278 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.1278 | 0.5 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1278 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1278 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 1 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.1278 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.1278 | 0.5 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.1278 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.