Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Leishmania major | prostaglandin f synthase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Onchocerca volvulus | 0.0032 | 0.3317 | 0.5 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0032 | 0.3317 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.3317 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 1 | 1 |
Onchocerca volvulus | 0.0032 | 0.3317 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.3317 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Onchocerca volvulus | 0.0032 | 0.3317 | 0.5 | |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0032 | 0.3317 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.3317 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.3317 | 0.5 |
Onchocerca volvulus | 0.0032 | 0.3317 | 0.5 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.3317 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0032 | 0.3317 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.3317 | 0.5 |
Onchocerca volvulus | 0.0032 | 0.3317 | 0.5 | |
Trypanosoma brucei | prostaglandin f synthase | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Onchocerca volvulus | 0.0032 | 0.3317 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0032 | 0.3317 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0032 | 0.3317 | 0.3317 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0032 | 0.3317 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Trypanosoma cruzi | aldo-keto reductase | 0.0032 | 0.3317 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.3317 | 0.3317 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.3317 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.3317 | 0.3317 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.