Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5312 | 0.5353 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.9922 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.9922 | 1 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0063 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.5312 | 0.5353 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.9922 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5312 | 0.5353 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.5312 | 0.2699 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.9922 | 1 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0041 | 0.4315 | 0.4349 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.9922 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.9922 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.9922 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.9922 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.9922 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.9922 | 0.9834 |
Brugia malayi | Matrixin family protein | 0.0042 | 0.4509 | 0.4544 |
Loa Loa (eye worm) | matrixin family protein | 0.0042 | 0.4509 | 0.1428 |
Brugia malayi | RNA binding protein | 0.0062 | 0.9922 | 1 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0038 | 0.3607 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.9922 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.0038 | 0.3607 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.9922 | 0.9834 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5312 | 0.5353 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.