Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.0177 | 0.0177 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0191 | 0.1899 | 0.2994 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0055 | 0.0436 | 0.0436 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1899 | 0.1899 |
Onchocerca volvulus | 0.0031 | 0.0177 | 0.0676 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0019 | 0.003 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0249 | 0.2525 | 0.2525 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0177 | 0.0177 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0177 | 0.0177 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.067 | 0.1242 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.067 | 0.7367 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.0177 | 0.0279 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0066 | 0.0556 | 0.8167 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0177 | 0.0177 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0191 | 0.1899 | 0.2994 |
Brugia malayi | glutaminase DH11.1 | 0.0304 | 0.3117 | 0.4914 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0066 | 0.0556 | 0.6022 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.0288 | 0.0288 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0126 | 0.1198 | 0.2277 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.0288 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1899 | 0.1899 |
Echinococcus multilocularis | tar DNA binding protein | 0.0399 | 0.4138 | 0.4138 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.0894 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0399 | 0.4138 | 0.4138 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0046 | 0.0072 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.0436 | 0.764 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0066 | 0.0556 | 0.6022 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus granulosus | hypothetical protein | 0.0065 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.067 | 0.1057 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0066 | 0.0556 | 0.8167 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0077 | 0.067 | 0.1242 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1899 | 0.1899 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0228 | 0.0359 |
Brugia malayi | Thioredoxin reductase | 0.0055 | 0.0436 | 0.0688 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.0177 | 0.0177 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.0177 | 0.0177 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0228 | 0.0228 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0077 | 0.067 | 0.1242 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.067 | 0.1057 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0019 | 0.0048 | 0.0035 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.0177 | 0.0177 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.067 | 0.1057 |
Schistosoma mansoni | apoferritin-2 | 0.0018 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0604 | 0.6342 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0917 | 0.9706 | 0.9706 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0288 | 0.0912 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.0436 | 0.764 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0048 | 0.0572 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0046 | 0.0072 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0019 | 0.0048 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0191 | 0.1899 | 0.1899 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0177 | 0.0279 |
Mycobacterium tuberculosis | Probable reductase | 0.0126 | 0.1198 | 0.2277 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0177 | 0.0279 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0154 | 0.1279 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0019 | 0.003 |
Mycobacterium ulcerans | beta-lactamase | 0.0077 | 0.067 | 0.2057 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.014 | 0.1349 | 0.2574 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0066 | 0.0556 | 0.6022 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0556 | 0.0556 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.0177 | 0.0676 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.0177 | 0.0676 |
Schistosoma mansoni | tar DNA-binding protein | 0.0399 | 0.4138 | 0.4138 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0046 | 0.0072 |
Schistosoma mansoni | apoferritin-2 | 0.0018 | 0.0037 | 0.0037 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0192 | 0.0192 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0077 | 0.067 | 0.1242 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0177 | 0.0177 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0077 | 0.067 | 0.067 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.0177 | 0.0177 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0192 | 0.2314 |
Onchocerca volvulus | 0.0028 | 0.0139 | 0.0531 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0192 | 0.0192 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0048 | 0.0027 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0048 | 0.0027 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0055 | 0.0436 | 0.6239 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0192 | 0.0192 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0037 | 0.0037 |
Echinococcus multilocularis | expressed protein | 0.0018 | 0.0037 | 0.0037 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0228 | 0.0619 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0192 | 0.0192 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0177 | 0.0177 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0048 | 0.0572 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0228 | 0.0228 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0019 | 0.0048 | 0.0035 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0048 | 0.0027 |
Mycobacterium leprae | Probable lipase LipE | 0.0077 | 0.067 | 0.4828 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1899 | 0.1899 |
Mycobacterium leprae | conserved hypothetical protein | 0.0077 | 0.067 | 0.4828 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0288 | 0.0912 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | beta-lactamase | 0.0077 | 0.067 | 0.1057 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0399 | 0.4138 | 0.6525 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0177 | 0.0177 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0154 | 0.0243 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0046 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0249 | 0.2525 | 0.3982 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.067 | 0.2057 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0154 | 0.1279 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0192 | 0.2314 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.067 | 0.2057 |
Loa Loa (eye worm) | TAR-binding protein | 0.0399 | 0.4138 | 0.6525 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0191 | 0.1899 | 0.1899 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0019 | 0.0048 | 0.0048 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0019 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.1899 | 0.2994 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0001 | 0.0002 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0191 | 0.1899 | 0.1899 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.067 | 0.1057 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0077 | 0.067 | 0.1057 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0228 | 1 |
Onchocerca volvulus | 0.0077 | 0.067 | 0.256 | |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.067 | 0.1057 |
Schistosoma mansoni | ferritin light chain | 0.0018 | 0.0037 | 0.0037 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0177 | 0.0279 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.0177 | 0.0177 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0192 | 0.0192 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0413 | 0.4285 | 0.6757 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0228 | 0.2147 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0556 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Schistosoma mansoni | glutaminase | 0.0304 | 0.3117 | 0.3117 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0191 | 0.1899 | 0.1899 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.0177 | 0.0177 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0019 | 0.0019 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.0436 | 0.4607 |
Schistosoma mansoni | lamin | 0.0028 | 0.0139 | 0.0139 |
Brugia malayi | RNA binding protein | 0.0399 | 0.4138 | 0.6525 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Onchocerca volvulus | 0.0028 | 0.0139 | 0.0531 | |
Giardia lamblia | Kinase, CMGC CLK | 0.0066 | 0.0556 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0048 | 0.0076 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0228 | 0.0228 |
Toxoplasma gondii | thioredoxin reductase | 0.0055 | 0.0436 | 0.6239 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0192 | 0.0303 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0228 | 0.0619 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0154 | 0.1279 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0019 | 0.0048 | 0.0035 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0055 | 0.0436 | 0.0688 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.067 | 0.7367 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0154 | 0.0243 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Mycobacterium ulcerans | hypothetical protein | 0.0077 | 0.067 | 0.2057 |
Loa Loa (eye worm) | beta-lactamase | 0.0077 | 0.067 | 0.1057 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | glutaminase 2 | 0.0304 | 0.3117 | 0.4914 |
Echinococcus granulosus | GPCR family 2 | 0.0191 | 0.1899 | 0.1899 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0139 | 0.0219 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.067 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0192 | 0.0192 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0288 | 0.0912 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0126 | 0.1198 | 0.2277 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.014 | 0.1349 | 1 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0066 | 0.0556 | 0.6022 |
Onchocerca volvulus | 0.0258 | 0.2619 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0249 | 0.2525 | 0.2525 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Onchocerca volvulus | 0.0077 | 0.067 | 0.256 | |
Echinococcus multilocularis | geminin | 0.0944 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.067 | 0.1057 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0098 | 0.0894 | 0.1409 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0228 | 0.0619 |
Brugia malayi | Protein kinase domain containing protein | 0.0066 | 0.0556 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0077 | 0.067 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0177 | 0.0279 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.067 | 0.067 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0077 | 0.067 | 0.1242 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0177 | 0.0279 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0288 | 0.0288 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0249 | 0.2525 | 0.2525 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0019 | 0.0048 | 0.0035 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0191 | 0.1899 | 0.2994 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0077 | 0.067 | 0.1242 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.0046 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0604 | 0.6342 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.0177 | 0.0279 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0048 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0413 | 0.4285 | 0.4285 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.0177 | 0.0177 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0154 | 0.2087 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0459 | 0.4782 | 0.4782 |
Loa Loa (eye worm) | hypothetical protein | 0.0413 | 0.4285 | 0.6757 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0077 | 0.067 | 0.1242 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0126 | 0.1198 | 0.2277 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0177 | 0.0279 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.0894 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0399 | 0.4138 | 0.4138 |
Brugia malayi | Protein kinase domain containing protein | 0.0098 | 0.0894 | 0.1409 |
Schistosoma mansoni | hypothetical protein | 0.0944 | 1 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0459 | 0.4782 | 0.4782 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0126 | 0.1198 | 0.8847 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.0894 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0227 | 0.2282 | 0.3598 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0177 | 0.0279 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.067 | 0.1242 |
Echinococcus granulosus | tar DNA binding protein | 0.0399 | 0.4138 | 0.4138 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0048 | 0.0027 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0249 | 0.2525 | 0.2525 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0177 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0139 | 0.0219 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0139 | 0.0219 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.014 | 0.1349 | 0.2574 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0154 | 0.2087 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0228 | 0.0228 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0459 | 0.4782 | 0.4782 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0177 | 0.0279 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0055 | 0.0436 | 0.0436 |
Echinococcus multilocularis | 0.0065 | 0.0545 | 0.0545 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0249 | 0.2525 | 0.2525 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.0894 | 0.0894 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0154 | 0.1705 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0139 | 0.0139 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0187 | 0.1145 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0139 | 0.0139 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | RNA binding protein | 0.0399 | 0.4138 | 0.6525 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0288 | 0.0912 |
Mycobacterium ulcerans | lipase LipD | 0.0077 | 0.067 | 0.2057 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0126 | 0.1198 | 0.2277 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0177 | 0.0279 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0077 | 0.067 | 0.2057 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0228 | 0.2147 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0228 | 0.2147 |
Treponema pallidum | NADH oxidase | 0.0019 | 0.0048 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0492 | 0.5135 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 0.6342 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | dual specificity | 0.0098 | 0.0894 | 0.0894 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0177 | 0.0177 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.067 | 0.067 |
Leishmania major | protein kinase, putative | 0.0066 | 0.0556 | 0.6022 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0228 | 0.0359 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0459 | 0.4782 | 0.4782 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0098 | 0.0894 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.0177 | 0.0177 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0001 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.067 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | ferritin | 0.0018 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0046 | 0.0072 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0048 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0043 | 0.0068 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0399 | 0.4138 | 0.6525 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0249 | 0.2525 | 0.3982 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.003 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.0177 | 0.0177 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0177 | 0.0279 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0077 | 0.067 | 0.2057 |
Trypanosoma brucei | trypanothione reductase | 0.0055 | 0.0436 | 0.4607 |
Brugia malayi | TAR-binding protein | 0.0399 | 0.4138 | 0.6525 |
Loa Loa (eye worm) | glutaminase | 0.0304 | 0.3117 | 0.4914 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0126 | 0.1198 | 0.2277 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.0177 | 0.0279 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0066 | 0.0556 | 0.0556 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.0177 | 0.0177 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.067 | 0.7367 |
Onchocerca volvulus | 0.0033 | 0.0192 | 0.0733 | |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0098 | 0.0894 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.0019 | 0.0019 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0077 | 0.067 | 0.067 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0019 | 0.003 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0177 | 0.0177 |
Echinococcus granulosus | expressed protein | 0.0018 | 0.0037 | 0.0037 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0098 | 0.0894 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.014 | 0.1349 | 0.2574 |
Onchocerca volvulus | 0.0077 | 0.067 | 0.256 | |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0187 | 0.0295 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0249 | 0.2525 | 0.2525 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0228 | 0.0619 |
Schistosoma mansoni | hypothetical protein | 0.0944 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0288 | 0.0455 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Leishmania major | trypanothione reductase | 0.0055 | 0.0436 | 0.4607 |
Echinococcus granulosus | dual specificity | 0.0098 | 0.0894 | 0.0894 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0139 | 0.0219 |
Schistosoma mansoni | ferritin light chain | 0.0018 | 0.0037 | 0.0037 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.0288 | 0.0288 |
Entamoeba histolytica | hypothetical protein | 0.0098 | 0.0894 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0134 | 0.0211 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0249 | 0.2525 | 0.2525 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0177 | 0.0177 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.067 | 0.2057 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.067 | 0.7367 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0037 | 0.0037 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0019 | 0.0048 | 0.0021 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Mycobacterium ulcerans | glutaminase | 0.0304 | 0.3117 | 1 |
Echinococcus granulosus | ferritin | 0.0018 | 0.0037 | 0.0037 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0066 | 0.0556 | 1 |
Echinococcus granulosus | lamin | 0.0028 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0545 | 0.086 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0177 | 0.0177 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0139 | 0.0139 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0228 | 0.2147 |
Trichomonas vaginalis | glutaminase, putative | 0.0304 | 0.3117 | 1 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0019 | 0.0048 | 0.0035 |
Leishmania major | protein kinase, putative | 0.0066 | 0.0556 | 0.6022 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0139 | 0.0219 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0154 | 0.1279 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0048 | 0.0048 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0077 | 0.067 | 0.1242 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0055 | 0.0436 | 0.0783 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0228 | 0.2887 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0066 | 0.0556 | 0.6022 |
Schistosoma mansoni | lamin | 0.0028 | 0.0139 | 0.0139 |
Trichomonas vaginalis | set domain proteins, putative | 0.0258 | 0.2619 | 0.8384 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0154 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0192 | 0.0303 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0179 | 0.0179 |
Echinococcus multilocularis | GPCR, family 2 | 0.0191 | 0.1899 | 0.1899 |
Plasmodium vivax | glutathione reductase, putative | 0.0055 | 0.0436 | 0.6239 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0604 | 0.6342 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.067 | 0.1057 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0048 | 0.0027 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0048 | 0.0048 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0066 | 0.0556 | 0.0556 |
Brugia malayi | glutathione reductase | 0.0055 | 0.0436 | 0.0688 |
Trichomonas vaginalis | esterase, putative | 0.0077 | 0.067 | 0.2057 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.0177 | 0.0177 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0066 | 0.0556 | 0.6022 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0066 | 0.0556 | 0.0877 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0177 | 0.0279 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0227 | 0.2282 | 0.3598 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0883 | 0.1392 |
Schistosoma mansoni | tar DNA-binding protein | 0.0399 | 0.4138 | 0.4138 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | glutathione reductase | 0.0055 | 0.0436 | 0.0688 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.0177 | 0.0676 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0048 | 0.0027 |
Schistosoma mansoni | tar DNA-binding protein | 0.0399 | 0.4138 | 0.4138 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0177 | 0.0279 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0037 | 0.0037 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.0177 | 0.0177 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.0894 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0066 | 0.0556 | 0.1686 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0883 | 0.1392 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.067 | 0.1242 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.067 | 0.1057 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0177 | 0.0177 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0154 | 0.1705 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.067 | 0.2057 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0154 | 0.0243 |
Toxoplasma gondii | ABC1 family protein | 0.0077 | 0.067 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0019 | 0.0019 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.