Detailed information for compound 772900

Basic information

Technical information
  • TDR Targets ID: 772900
  • Name: 1-(4-fluorophenyl)-7-methyl-2-pyridin-2-yl-1H -chromeno[2,3-c]pyrrole-3,9-dione
  • MW: 386.375 | Formula: C23H15FN2O3
  • H donors: 0 H acceptors: 3 LogP: 3.78 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C1N(c2ccccn2)C(=O)c2c1c(=O)c1c(o2)ccc(c1)C
  • InChi: 1S/C23H15FN2O3/c1-13-5-10-17-16(12-13)21(27)19-20(14-6-8-15(24)9-7-14)26(23(28)22(19)29-17)18-4-2-3-11-25-18/h2-12,20H,1H3
  • InChiKey: NGVGJWRODWJTPG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-fluorophenyl)-7-methyl-2-(2-pyridyl)-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(4-fluorophenyl)-7-methyl-2-(2-pyridyl)-1H-chromeno[2,3-c]pyrrole-3,9-quinone
  • STOCK4S-39213

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0017 0.0686
Echinococcus granulosus pyruvate kinase 0.0034 0.0017 0.0016
Plasmodium vivax pyruvate kinase, putative 0.0066 0.0047 0.5607
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0047 0.1887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0027 0.1086
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0148 0.5926
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0009 0.0262
Schistosoma mansoni nuclear receptor 0.002 0.0005 0.0003
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0017 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Echinococcus granulosus tar DNA binding protein 0.0333 0.0296 0.0294
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0047 0.1887
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Onchocerca volvulus 0.0203 0.0175 0.0171
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0005 0.0145
Echinococcus multilocularis mothers against decapentaplegic 2 0.0042 0.0025 0.0023
Loa Loa (eye worm) Smad1 0.0093 0.0073 0.0071
Echinococcus multilocularis neuropeptide s receptor 0.0499 0.0451 0.0449
Onchocerca volvulus 0.01 0.0079 0.0074
Brugia malayi hypothetical protein 0.002 0.0005 0.0003
Brugia malayi Pyruvate kinase, muscle isozyme 0.0066 0.0047 0.0046
Loa Loa (eye worm) MH2 domain-containing protein 0.1366 0.1258 0.1257
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0012 0.1076
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0002 0.0078
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0047 0.1679
Loa Loa (eye worm) hypothetical protein 0.011 0.0088 0.0087
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0269 0.0267
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0334 0.0297 0.0295
Onchocerca volvulus Huntingtin homolog 0.0122 0.0099 0.0094
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.025 0.8604
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0093 0.0092
Leishmania major GTP-binding protein, putative 0.0021 0.0005 0.02
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0007 0.0006
Loa Loa (eye worm) TAR-binding protein 0.0333 0.0296 0.0294
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0007 0.0006
Schistosoma mansoni alpha glucosidase 0.0038 0.0022 0.002
Brugia malayi RNA recognition motif domain containing protein 0.0333 0.0296 0.0294
Echinococcus granulosus carbonic anhydrase 0.011 0.0088 0.0087
Echinococcus multilocularis neuropeptide receptor A26 0.0499 0.0451 0.0449
Echinococcus multilocularis GPCR, family 2 0.0298 0.0263 0.0262
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.014 0.0135
Schistosoma mansoni smad 0.0042 0.0025 0.0023
Echinococcus multilocularis pyruvate kinase 0.0034 0.0017 0.0016
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.0083 0.3047
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.003 0.0028
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0022 0.08
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0026 0.0025
Schistosoma mansoni fkbp-rapamycin associated protein 0.0019 0.0003 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0147 0.0145
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0005 0.0003
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0012 0.0406
Toxoplasma gondii target of rapamycin (TOR), putative 0.0051 0.0034 0.3165
Echinococcus multilocularis pyruvate kinase 0.0066 0.0047 0.0046
Brugia malayi PAS domain containing protein 0.0042 0.0025 0.0024
Schistosoma mansoni pyruvate kinase 0.0034 0.0017 0.0016
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0103 0.7539
Brugia malayi MH1 domain containing protein 0.0051 0.0034 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0103 0.0101
Schistosoma mansoni cpg binding protein 0.0035 0.0018 0.0017
Echinococcus multilocularis snurportin 1 0.0304 0.0269 0.0267
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0572
Loa Loa (eye worm) hypothetical protein 0.0122 0.0099 0.0098
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0021 0.0019
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0001 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Schistosoma mansoni carbonic anhydrase 0.011 0.0088 0.0087
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.003 0.0944
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0115 0.8456
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0062 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.0135 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0203 0.0175 0.0174
Loa Loa (eye worm) hypothetical protein 0.0066 0.0047 0.0046
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0115 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0012 0.0011
Brugia malayi nuclear receptor NHR-88 0.002 0.0005 0.0003
Brugia malayi Importin beta-1 subunit 0.0028 0.0012 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Brugia malayi 6-phosphofructokinase 0.0115 0.0093 0.0092
Leishmania major hypothetical protein, conserved 0.0104 0.0083 0.3085
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.003 0.2097
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0017 0.0015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0035 0.0033
Schistosoma mansoni hypothetical protein 0.0052 0.0035 0.0033
Brugia malayi TAR-binding protein 0.0333 0.0296 0.0294
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.0221 0.0219
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0019 0.1319
Echinococcus granulosus chromobox protein 1 0.0061 0.0042 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0203 0.0175 0.0174
Leishmania major carbonic anhydrase-like protein 0.0203 0.0175 0.6496
Schistosoma mansoni chromobox protein 0.0061 0.0042 0.0041
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0021 0.0816
Schistosoma mansoni hypothetical protein 0.0743 0.0678 0.0677
Echinococcus granulosus lamin dm0 0.0084 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0005 0.0003
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.003 0.0944
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0026 0.0025
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0024 0.0022
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0007 0.0288
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0019 0.0003 0.0002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0022 0.0857
Brugia malayi Smad1 0.0093 0.0073 0.0071
Echinococcus multilocularis expressed protein 0.0018 0.0003 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0103 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0026 0.0025
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0028 0.0026
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0026 0.0025
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.003 0.1127
Brugia malayi MH1 domain containing protein 0.0093 0.0073 0.0071
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.002 0.0795
Echinococcus multilocularis sodium bile acid cotransporter 1.0752 1 1
Echinococcus granulosus cpg binding protein 0.0035 0.0018 0.0017
Brugia malayi hypothetical protein 0.0104 0.0083 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0022 0.0749
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0047 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Onchocerca volvulus 0.0084 0.0064 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.003 0.1127
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0093 0.0092
Echinococcus multilocularis tar DNA binding protein 0.0333 0.0296 0.0294
Echinococcus granulosus ferritin 0.0018 0.0003 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0083 0.3047
Leishmania major pyruvate kinase 0.0066 0.0047 0.1754
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0026 0.0025
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0026 0.0025
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0088 0.0087
Brugia malayi hypothetical protein 0.0023 0.0007 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Echinococcus multilocularis pyruvate kinase 0.0034 0.0017 0.0016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0021 0.2332
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Echinococcus granulosus lamin 0.0084 0.0064 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0021 0.1355
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0326
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0625
Giardia lamblia Pyruvate kinase 0.0034 0.0017 0.0492
Echinococcus granulosus mothers against decapentaplegic 2 0.0042 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0203 0.0175 0.0174
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0047 0.0042
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0062 0.0044 0.1631
Brugia malayi Nuclear hormone receptor E75 0.002 0.0005 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0022 0.002
Brugia malayi conserved hypotetical protein 0.002 0.0005 0.0003
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0064 0.0063
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0026 0.0025
Echinococcus multilocularis chromobox protein 1 0.0061 0.0042 0.0041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0007 0.0288
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0015 0.1544
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0093 0.8079
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0115 0.8468
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0026 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0026 0.0025
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0015 0.05
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0062 0.0044 0.1418
Schistosoma mansoni nuclear hormone receptor 0.002 0.0005 0.0003
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0005 0.0003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0026 0.0025
Loa Loa (eye worm) DR-78 0.002 0.0005 0.0003
Entamoeba histolytica Ran family GTPase 0.0021 0.0005 0.0071
Echinococcus granulosus dnaJ subfamily B 0.047 0.0424 0.0423
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Echinococcus granulosus pyruvate kinase 0.0034 0.0017 0.0016
Trichomonas vaginalis chromobox protein, putative 0.0037 0.002 0.0792
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0026 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0022 0.0749
Schistosoma mansoni hypothetical protein 0.0047 0.003 0.0028
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0326 0.029 0.0288
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0034 0.0017 0.059
Echinococcus multilocularis pyruvate kinase 0.0052 0.0034 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Schistosoma mansoni Smad4 0.0093 0.0073 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0026 0.0025
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0062 0.0044 0.1584
Echinococcus granulosus chromobox protein 1 0.0061 0.0042 0.0041
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0005 0.0145
Echinococcus multilocularis dnaJ subfamily B 0.047 0.0424 0.0423
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0026 0.0025
Brugia malayi ecdysone receptor 0.002 0.0005 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0103 0.7539
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Onchocerca volvulus 0.0033 0.0017 0.0012
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0103 0.3808
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0026 0.0025
Brugia malayi nuclear receptor NHR-67 0.002 0.0005 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Toxoplasma gondii pyruvate kinase PyK1 0.0066 0.0047 0.4528
Schistosoma mansoni alpha-glucosidase 0.0149 0.0124 0.0123
Onchocerca volvulus Huntingtin homolog 0.0122 0.0099 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0029 0.0886
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0003 0.0127
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0093 0.6856
Loa Loa (eye worm) transcription factor SMAD2 0.1366 0.1258 0.1257
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0007 0.0006
Echinococcus granulosus single minded 2 0.0031 0.0015 0.0014
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0026 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0026 0.0025
Brugia malayi nuclear receptor NHR-88 0.0043 0.0026 0.0025
Entamoeba histolytica hypothetical protein 0.0023 0.0007 0.014
Schistosoma mansoni microtubule-associated protein tau 0.0749 0.0684 0.0682
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.027 1
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0015 0.1326
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0644 0.0585 0.0584
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0047 0.1725
Brugia malayi MH1 domain containing protein 0.0093 0.0073 0.0071
Loa Loa (eye worm) MH2 domain-containing protein 0.0093 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.0188 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0104 0.0083 0.0082
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0572
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0047 0.1679
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0326 0.029 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0026 0.0025
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0093 0.3139
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0026 0.0021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0024 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Mycobacterium leprae Probable pyruvate kinase PykA 0.0066 0.0047 0.3985
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0021 0.0019
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0027
Schistosoma mansoni chromobox protein 0.0061 0.0042 0.0041
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0005 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Loa Loa (eye worm) nuclear factor I 0.0051 0.0034 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0093 0.0092
Brugia malayi hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis chromobox protein 1 0.0061 0.0042 0.0041
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0093 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4181 0.388 0.3879
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0005 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0063 0.0061
Loa Loa (eye worm) RNA binding protein 0.0333 0.0296 0.0294
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0005 0.0145
Loa Loa (eye worm) hypothetical protein 0.003 0.0014 0.0012
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0019 0.2032
Brugia malayi Nuclear hormone receptor E75 0.002 0.0005 0.0003
Schistosoma mansoni sodium-bile acid cotransporter 0.6392 0.5939 0.5939
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0015 0.059
Schistosoma mansoni hypothetical protein 0.0304 0.0269 0.0267
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0334 0.0297 0.0295
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0019 0.1307
Brugia malayi chromobox protein homolog 3 0.0034 0.0018 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0034 0.0018 0.0013
Loa Loa (eye worm) hypoxia-induced factor 1 0.0131 0.0108 0.0106
Brugia malayi intermediate filament protein 0.0084 0.0064 0.0063
Brugia malayi Calcitonin receptor-like protein seb-1 0.0942 0.0863 0.0862
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0017 0.0015
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0034 0.0017 0.059
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0022 0.0636
Schistosoma mansoni ap endonuclease 0.0037 0.0021 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0021 0.0816
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0326
Trichomonas vaginalis set domain proteins, putative 0.023 0.0201 0.8023
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0047 0.1708
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0026 0.0025
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.011 0.0088 0.0087
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0015 0.1326
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0088 0.0087
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0015 0.1643
Echinococcus multilocularis transfer RNA-Lys 0.0031 0.0015 0.0014
Echinococcus granulosus intermediate filament protein 0.0084 0.0064 0.0063
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0093 0.3139
Brugia malayi ecdysteroid receptor 0.0043 0.0026 0.0025
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0034 0.0017 0.0016
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0003 0.0079
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0047 0.0046
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0026 0.0025
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0026 0.0907
Plasmodium falciparum carbonic anhydrase 0.011 0.0088 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0047 0.1679
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0333 0.0296 0.0294
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0103 1
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0035 0.1232
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0083 0.9401
Echinococcus multilocularis cpg binding protein 0.0035 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.0644 0.0585 0.0584
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0334 0.0297 0.0295
Onchocerca volvulus 0.0027 0.0011 0.0006
Brugia malayi tailless protein 0.002 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0044 0.1754
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0017 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0007 0.0006
Schistosoma mansoni single-minded 0.0042 0.0025 0.0024
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0026 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0093 0.0092
Schistosoma mansoni ran 0.0021 0.0005 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0093 0.0092
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0022 0.0857
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0003 0.0002
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0093 0.0092
Schistosoma mansoni smad 0.0093 0.0073 0.0071
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Schistosoma mansoni cpg binding protein 0.0035 0.0018 0.0017
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0005 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0026 0.0025
Schistosoma mansoni ap endonuclease 0.0037 0.0021 0.0019
Echinococcus granulosus sodium bile acid cotransporter 1.0752 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0021 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0207
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Schistosoma mansoni Smad4 0.0042 0.0025 0.0023
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0017 0.1574
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis sodium bile acid cotransporter 1.0752 1 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0005 0.0004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0267 0.0235 0.0233
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0026 0.0025
Brugia malayi hypothetical protein 0.0142 0.0118 0.0117
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.003 0.0014 0.0455
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0005 0.0003
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0019 0.2161
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Toxoplasma gondii exonuclease III APE 0.0037 0.0021 0.1883
Loa Loa (eye worm) hypothetical protein 0.0942 0.0863 0.0862
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0005 0.0003
Giardia lamblia GTOR 0.0062 0.0044 0.1578
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0014 0.1191
Brugia malayi CXXC zinc finger family protein 0.0033 0.0017 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0061 0.0042 0.169
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0062 0.0044 0.1584
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Schistosoma mansoni coup transcription factor 0.0043 0.0026 0.0025
Echinococcus multilocularis geminin 0.0743 0.0678 0.0677
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0026 0.0025
Echinococcus multilocularis smad 0.0093 0.0073 0.0071
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0011 0.0368
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0007 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0298 0.0263 0.0262
Onchocerca volvulus 0.0043 0.0026 0.0021
Echinococcus granulosus sodium bile acid cotransporter 1.0752 1 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0147 0.0145
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0062 0.0044 0.0042
Echinococcus granulosus neuropeptide receptor A26 0.0499 0.0451 0.0449
Echinococcus granulosus serine protein kinase ATM 0.0034 0.0017 0.0016
Plasmodium vivax importin-beta 2, putative 0.0028 0.0012 0.1333
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0064 0.0063
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0022 0.0857
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0003 0.0079
Echinococcus granulosus microtubule associated protein 2 0.0749 0.0684 0.0682
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0021 0.0019
Echinococcus granulosus tumor protein p63 0.139 0.1281 0.1279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0003 0.0127
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0044 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Echinococcus multilocularis pyruvate kinase 0.0066 0.0047 0.0046
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0026 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0026 0.0907
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0026 0.0025
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0005 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0334 0.0297 0.0295
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0026 0.0025
Brugia malayi mothers against decapentaplegic homolog 3 0.0042 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0009
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0025 0.0023
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0047 0.0045
Echinococcus multilocularis muscleblind protein 0.0155 0.013 0.0129
Brugia malayi follicle stimulating hormone receptor 0.0267 0.0235 0.0233
Brugia malayi nuclear hormone receptor 0.0043 0.0026 0.0025
Brugia malayi AMP-binding enzyme family protein 0.0048 0.003 0.0029
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0021 0.2192
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0203 0.0175 0.0174
Echinococcus multilocularis tumor protein p63 0.139 0.1281 0.1279
Loa Loa (eye worm) hypothetical protein 0.0122 0.0099 0.0098
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0005 0.0477
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0022 0.002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0007 0.0219
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0053 0.0036 0.1322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Schistosoma mansoni pyruvate kinase 0.0066 0.0047 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.0156 0.6245
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0026 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0026 0.0025
Echinococcus granulosus expressed protein 0.0018 0.0003 0.0001
Entamoeba histolytica hypothetical protein 0.0034 0.0017 0.0487
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0026 0.0025
Echinococcus multilocularis sodium bile acid cotransporter 1.0752 1 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0093 0.0073 0.0071
Brugia malayi Pre-SET motif family protein 0.003 0.0014 0.0012
Leishmania major mitochondrial DNA polymerase beta 0.0305 0.027 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0021 0.1423
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0021 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0025 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0044 0.1754
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0014 0.0012
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0062 0.0044 0.1584
Onchocerca volvulus 0.0048 0.003 0.0026
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0021 0.071
Toxoplasma gondii FATC domain-containing protein 0.0034 0.0017 0.1563
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.012 0.4427
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0022 0.002
Schistosoma mansoni intermediate filament proteins 0.0084 0.0064 0.0063
Plasmodium vivax SET domain protein, putative 0.003 0.0014 0.1474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0047 0.1708
Plasmodium falciparum importin beta, putative 0.0028 0.0012 0.1253
Loa Loa (eye worm) hypothetical protein 0.0142 0.0118 0.0117
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0093 0.3459
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0021 0.0762
Loa Loa (eye worm) hypothetical protein 0.0298 0.0263 0.0262
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.025 0.8604
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Trichomonas vaginalis ran, putative 0.0021 0.0005 0.0209
Brugia malayi Pre-SET motif family protein 0.0203 0.0175 0.0173
Echinococcus granulosus GPCR family 2 0.0298 0.0263 0.0262
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.003 0.2097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.002 0.0795
Mycobacterium ulcerans pyruvate kinase 0.0066 0.0047 0.337
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0006 0.0216
Trichomonas vaginalis ferritin, putative 0.0018 0.0003 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0026 0.0025
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0026 0.0025
Schistosoma mansoni lamin 0.0084 0.0064 0.0063
Echinococcus multilocularis mothers against decapentaplegic 5 0.0093 0.0073 0.0071
Echinococcus multilocularis mothers against decapentaplegic 6 0.0042 0.0025 0.0023
Echinococcus multilocularis carbonic anhydrase 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.003 0.2097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.003 0.1214
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0203 0.0175 0.6476
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0191 0.0164 0.0159
Echinococcus granulosus pyruvate kinase 0.0066 0.0047 0.0046
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0012 0.001
Echinococcus granulosus pyruvate kinase 0.0034 0.0017 0.0016
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0047 0.1506
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0191 0.0164 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0048 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0148 0.5926
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0026 0.0907
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0083 0.3047
Brugia malayi Pyruvate kinase, M2 isozyme 0.0066 0.0047 0.0046
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.0083 0.8075
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0017 0.0625
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Echinococcus granulosus pyruvate kinase 0.0066 0.0047 0.0046
Echinococcus multilocularis Smad4 0.0093 0.0073 0.0071
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0017 0.1833
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0017 0.0572
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0042 0.0025 0.002
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0021 0.0005 0.0381
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus mothers against decapentaplegic 5 0.0093 0.0073 0.0071
Schistosoma mansoni lamin 0.0084 0.0064 0.0063
Echinococcus multilocularis carbonic anhydrase II 0.0203 0.0175 0.0174
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0015 0.1643
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0005 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0015 0.1544
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0026 0.0025
Schistosoma mansoni apoferritin-2 0.0018 0.0003 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0026 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0334 0.0297 0.0295
Brugia malayi MH2 domain containing protein 0.0093 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0021
Onchocerca volvulus 0.0084 0.0064 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0026 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Brugia malayi RNA, U transporter 1 0.0081 0.0061 0.006
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0203 0.0175 0.0174
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0334 0.0297 0.0295
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.003 0.1127
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.002 0.0015
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0021 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0025 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0024 0.0959
Trypanosoma cruzi target of rapamycin kinase 3 0.0053 0.0036 0.1274
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.003 0.0028
Echinococcus granulosus mothers against decapentaplegic 6 0.0042 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.0029
Echinococcus granulosus carbonic anhydrase 0.011 0.0088 0.0087
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Brugia malayi MH2 domain containing protein 0.0042 0.0025 0.0023
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0017 0.0015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.003 0.2097
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0093 0.3423
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0942 0.0863 0.0862
Leishmania major importin beta-1 subunit, putative 0.0023 0.0007 0.0274
Schistosoma mansoni hypothetical protein 0.0326 0.029 0.0288
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0015 0.1326
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0005 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Onchocerca volvulus 0.004 0.0023 0.0018
Brugia malayi steroid hormone receptor 0.0043 0.0026 0.0025
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0298 0.0263 0.0262
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0034 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0022 0.0879
Chlamydia trachomatis pyruvate kinase 0.0066 0.0047 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Echinococcus granulosus neuropeptide s receptor 0.0499 0.0451 0.0449
Schistosoma mansoni smad1 5 8 and 0.0093 0.0073 0.0071
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Brugia malayi hypothetical protein 0.0067 0.0049 0.0047
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0298 0.0263 0.0262
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.027 1
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0005 0.0003
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0066 0.0047 0.3422
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.025 1
Echinococcus granulosus importin subunit beta 1 0.0028 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0002
Echinococcus granulosus muscleblind protein 0.0155 0.013 0.0129
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.003 0.2159
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0029 0.0027
Trypanosoma brucei pyruvate kinase 1 0.0066 0.0047 0.1708
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0083 0.9401
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni sodium-bile acid cotransporter related 0.436 0.4047 0.4046
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0005 0.0003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0103 0.7558
Schistosoma mansoni aryl hydrocarbon receptor 0.0042 0.0025 0.0024
Loa Loa (eye worm) carbonic anhydrase 3 0.0203 0.0175 0.0174
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0005 0.0003
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0203 0.0175 0.6476
Mycobacterium ulcerans hypothetical protein 0.0161 0.0135 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.012 0.4457
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0188 0.0161 0.0159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0005 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0021 0.071
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0005 0.0385
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0047 0.0042
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0093 0.6831
Brugia malayi nuclear receptor RXR 0.002 0.0005 0.0003
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0005 0.0449
Loa Loa (eye worm) hypothetical protein 0.0034 0.0018 0.0016
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0004
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0022 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0015 0.059
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0155 0.013 0.0129
Echinococcus granulosus smad 0.0093 0.0073 0.0071
Schistosoma mansoni smad1 5 8 and 0.0093 0.0073 0.0071
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0026 0.0907
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0093 0.0073 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0334 0.0297 0.0295
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0006 0.0161
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.025 1
Schistosoma mansoni ferritin light chain 0.0018 0.0003 0.0001
Brugia malayi Cytochrome P450 family protein 0.003 0.0014 0.0012
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0026 0.0025
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0088 0.0087
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0147 0.0145
Schistosoma mansoni apoferritin-2 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0155 0.013 0.0129
Echinococcus granulosus sodium bile acid cotransporter 1.0752 1 1
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0225 0.0224
Schistosoma mansoni hypothetical protein 0.011 0.0088 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0053 0.0036 0.1274
Brugia malayi hypothetical protein 0.0023 0.0007 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0014 0.0012
Schistosoma mansoni sodium-bile acid cotransporter related 1.0752 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0002 0.0078
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0021 0.071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0334 0.0297 0.0295
Trypanosoma brucei carbonic anhydrase-like protein 0.0203 0.0175 0.6476
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0026 0.0025
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Toxoplasma gondii hypothetical protein 0.0049 0.0032 0.2983
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0022 0.1984
Schistosoma mansoni cpg binding protein 0.0033 0.0017 0.0015
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0005 0.0003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0019 0.125
Echinococcus multilocularis serine protein kinase ATM 0.0034 0.0017 0.0016
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0021 0.062
Brugia malayi Heterochromatin protein 1 0.0061 0.0042 0.0041
Schistosoma mansoni survival motor neuron protein 0.0052 0.0035 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.014 0.5594
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.003 0.2097
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0015 0.0404
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0257 0.0225 0.0224
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.003 0.248
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.003 0.2097
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Leishmania major pyruvate kinase 0.0066 0.0047 0.1754
Schistosoma mansoni zinc finger protein 0.002 0.0005 0.0003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0942 0.0863 0.0862
Plasmodium falciparum pyruvate kinase 0.0066 0.0047 0.5272
Trypanosoma brucei glucosidase, putative 0.0038 0.0022 0.0749
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0203 0.0175 0.0174
Schistosoma mansoni Smad4 0.0042 0.0025 0.0023
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0093 0.3139
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0017 0.1183
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0034 0.1335
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0062 0.0044 0.1631
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0017 0.195
Echinococcus multilocularis carbonic anhydrase 0.011 0.0088 0.0087
Schistosoma mansoni ran 0.0021 0.0005 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0037 0.002 0.0792
Mycobacterium ulcerans putative regulatory protein 0.0031 0.0015 0.0944
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0052 0.0051
Echinococcus multilocularis ferritin 0.0018 0.0003 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0103 0.0101
Brugia malayi MH1 domain containing protein 0.0051 0.0034 0.0032
Brugia malayi 6-phosphofructokinase 0.0115 0.0093 0.0092
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0005 0.0003
Schistosoma mansoni importin beta-1 0.0028 0.0012 0.0011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0103 0.7539
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0018 0.0696
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.012 0.4427
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0002 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0017 0.0016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.003 0.0944
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Onchocerca volvulus 0.023 0.0201 0.0196
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0147 0.0145
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.003 0.248
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0026 0.0025
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0225 0.0224
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0026 0.0025
Brugia malayi MH2 domain containing protein 0.1366 0.1258 0.1257
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0026 0.0025
Schistosoma mansoni ferritin light chain 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.011 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 1.0752 1 1
Onchocerca volvulus 0.0052 0.0035 0.003
Echinococcus multilocularis lamin dm0 0.0084 0.0064 0.0063
Toxoplasma gondii hypothetical protein 0.011 0.0088 0.8589
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0021 0.0019
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0017 0.0572
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0021 0.002
Brugia malayi N-terminal motif family protein 0.0191 0.0164 0.0163
Echinococcus multilocularis lamin 0.0084 0.0064 0.0063
Schistosoma mansoni hypothetical protein 0.0298 0.0263 0.0262
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0019 0.0003 0.0069
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.003 0.2097
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0175 0.0173
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0062 0.0044 0.1418
Schistosoma mansoni cellular tumor antigen P53 0.0203 0.0175 0.0174
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0048 0.003 0.0029
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0088 0.0087
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0062 0.0044 0.1584
Echinococcus multilocularis microtubule associated protein 2 0.0749 0.0684 0.0682
Brugia malayi nuclear receptor RXR 0.0023 0.0007 0.0006
Loa Loa (eye worm) heterochromatin protein 1 0.0061 0.0042 0.0041
Brugia malayi bHLH-PAS transcription factor 0.0031 0.0015 0.0014
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0007 0.0288
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0021
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0012 0.0406
Schistosoma mansoni alpha-glucosidase 0.0149 0.0124 0.0123
Echinococcus multilocularis carbonic anhydrase 0.011 0.0088 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0061 0.0042 0.169
Brugia malayi hypothetical protein 0.0326 0.029 0.0288
Brugia malayi hypoxia-induced factor 1 0.0131 0.0108 0.0106
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0062 0.0044 0.0042
Schistosoma mansoni carbonic anhydrase-related 0.011 0.0088 0.0087
Schistosoma mansoni hypothetical protein 0.047 0.0424 0.0423
Echinococcus multilocularis pyruvate kinase 0.0034 0.0017 0.0016
Echinococcus multilocularis muscleblind protein 1 0.0155 0.013 0.0129
Brugia malayi hypothetical protein 0.0122 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0017 0.0667
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0026 0.0025
Echinococcus multilocularis musashi 0.0084 0.0064 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0093 0.3423
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0026 0.0021
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0028 0.0026
Schistosoma mansoni nuclear hormone receptor 0.002 0.0005 0.0003
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.0221 0.0219
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0015 0.039
Echinococcus granulosus Smad4 0.0093 0.0073 0.0071
Schistosoma mansoni smad1 5 8 and 0.0093 0.0073 0.0071
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0045 0.4316
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0014 0.0012
Echinococcus granulosus geminin 0.0743 0.0678 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0026 0.0025
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0047 0.0045
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0334 0.0297 0.0295
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0019 0.0003 0.0002
Entamoeba histolytica hypothetical protein 0.0326 0.029 1
Schistosoma mansoni tar DNA-binding protein 0.0333 0.0296 0.0294
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0305 0.027 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0026 0.0025
Echinococcus granulosus carbonic anhydrase 0.011 0.0088 0.0087
Echinococcus granulosus carbonic anhydrase II 0.0203 0.0175 0.0174
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Giardia lamblia Pyruvate kinase 0.0066 0.0047 0.1714
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.011 0.0088 0.0087
Schistosoma mansoni ferritin 0.0018 0.0003 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.0743 0.0678 0.0677
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0026 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0093 0.3729
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.001
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.003 0.2159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.002 0.0795
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0022 0.0636
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.025 1
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0084 0.0064 0.0063
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.011 0.0088 0.0087
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0103 0.0101
Brugia malayi phosphofructokinase 0.0115 0.0093 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0023 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0093 0.3669
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0093 0.0073 0.0071
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.011 0.0088 0.0087
Brugia malayi Latrophilin receptor protein 2 0.0298 0.0263 0.0262
Brugia malayi latrophilin 2 splice variant baaae 0.0644 0.0585 0.0584
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0047 0.0042
Brugia malayi RNA binding protein 0.0333 0.0296 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Brugia malayi Muscleblind-like protein 0.0155 0.013 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0044 0.1754
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0025 0.1
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.0083 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trypanosoma brucei pyruvate kinase 1, putative 0.0066 0.0047 0.1708
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0047 0.0045
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0021 0.06
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0018 0.0696
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0022 0.0857
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0006
Loa Loa (eye worm) MH1 domain-containing protein 0.0093 0.0073 0.0071
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0298 0.0263 0.0262
Schistosoma mansoni pyruvate kinase 0.0066 0.0047 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0221 0.8825
Onchocerca volvulus 0.0031 0.0015 0.001
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0022 0.0857
Brugia malayi nuclear hormone receptor 0.002 0.0005 0.0003
Mycobacterium ulcerans hypothetical protein 0.0048 0.003 0.2097
Schistosoma mansoni transcription factor LCR-F1 0.0326 0.029 0.0288
Echinococcus granulosus snurportin 1 0.0304 0.0269 0.0267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0027 0.1086
Onchocerca volvulus 1.0752 1 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0298 0.0263 0.0262
Schistosoma mansoni nuclear receptor 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0018
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0298 0.0263 0.0262
Brugia malayi hypothetical protein 0.0257 0.0225 0.0224
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0147 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0036 0.1419
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0007 0.0006
Brugia malayi MH2 domain containing protein 0.0093 0.0073 0.0071

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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