Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.3114 | 0.7399 |
Schistosoma mansoni | chromobox protein | 0.0068 | 1 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 1 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.9962 | 0.9962 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.9962 | 0.9962 |
Schistosoma mansoni | chromobox protein | 0.0068 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.9962 | 0.9962 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 1 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.3781 | 0.3419 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0068 | 0.9962 | 0.9962 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 1 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0 | 0.5 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.3781 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.3781 | 0.3419 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.3114 | 0.2714 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3114 | 0.3114 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.3114 | 0.2714 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.9962 | 0.9962 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.9962 | 0.9962 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.1217 | 0.1217 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.3114 | 0.3114 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.