Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2667 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.4678 | 1 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.2667 | 0.2966 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.2667 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.4393 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2667 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2667 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0109 | 0.0056 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2667 | 0.2628 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.2667 | 0.6023 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.092 | 0.1996 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.2667 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.2667 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.4393 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.1257 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2667 | 0.2628 |
Onchocerca volvulus | 0.003 | 0.4393 | 1 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.8867 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.4678 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0939 | 0.2042 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2667 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.1257 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0584 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4678 | 0.465 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0004 | 0.0053 | 0.0199 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.2667 | 0.6023 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1916 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.2667 | 0.5651 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.1257 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.2667 | 1 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.1257 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.2667 | 0.5 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0004 | 0.0053 | 0.0199 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.2667 | 0.5651 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4678 | 0.465 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4393 | 0.4363 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1916 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.2667 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.