Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Brugia malayi | Dihydrofolate reductase | 0.5477 | 1 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0035 | 0.0031 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0195 | 0.0184 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Trichomonas vaginalis | lysyl-tRNA synthetase, putative | 0.0025 | 0.0011 | 0.0211 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0033 | 0.0026 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.0508 | 0.0505 |
Loa Loa (eye worm) | CAMK/CAMK2 protein kinase | 0.0034 | 0.0028 | 0.0023 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0036 | 0.1152 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0067 | 0.0065 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0172 | 0.0281 | 0.0278 |
Echinococcus multilocularis | calcium dependent protein kinase | 0.0032 | 0.0024 | 0.0021 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Trichomonas vaginalis | glucose transporter, putative | 0.0034 | 0.0028 | 0.0878 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0036 | 0.1152 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0035 | 0.0031 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0026 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0045 | 0.0041 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0036 | 0.0052 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0038 | 0.0036 | 0.1152 |
Trypanosoma cruzi | hexose transporter | 0.0034 | 0.0028 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0098 | 0.0094 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0026 | 0.0054 |
Trichomonas vaginalis | prolyl-tRNA synthetase, putative | 0.0033 | 0.0026 | 0.08 |
Schistosoma mansoni | hypothetical protein | 0.0352 | 0.061 | 0.0608 |
Brugia malayi | isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0015 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0035 | 0.0031 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0032 |
Plasmodium falciparum | protein kinase 6 | 0.0468 | 0.0823 | 0.1713 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0008 | 0.0006 |
Onchocerca volvulus | 0.0049 | 0.0055 | 0.0344 | |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.0055 | 0.0053 |
Schistosoma mansoni | lysyl-tRNA synthetase | 0.0025 | 0.0011 | 0.0009 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0023 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0067 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0037 | 0.0033 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0067 | 0.0065 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0035 | 0.1141 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0035 | 0.0052 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0035 | 0.0025 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.5477 | 1 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0033 | 0.0031 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0172 | 0.0281 | 0.0277 |
Plasmodium vivax | calcium-dependent protein kinase 1, putative | 0.0034 | 0.0028 | 0.0035 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0035 | 0.0031 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.0084 | 0.0082 |
Echinococcus granulosus | calcium dependent protein kinase | 0.0032 | 0.0024 | 0.0021 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0055 | 0.0044 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.0055 | 0.0053 |
Plasmodium falciparum | mitogen-activated protein kinase 2 | 0.0178 | 0.0292 | 0.0593 |
Entamoeba histolytica | prolyl-tRNA synthetase, putative | 0.0033 | 0.0026 | 0.6258 |
Echinococcus multilocularis | General substrate transporter | 0.0095 | 0.0139 | 0.0137 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0035 | 0.0033 |
Plasmodium falciparum | hexose transporter | 0.011 | 0.0168 | 0.0331 |
Brugia malayi | bifunctional aminoacyl-tRNA synthetase | 0.0033 | 0.0026 | 0.0016 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0035 | 0.0031 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0035 | 0.1141 |
Echinococcus multilocularis | zinc finger transcription factor gli2 | 0.0301 | 0.0517 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Schistosoma mansoni | alpha glucosidase | 0.0038 | 0.0036 | 0.0033 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0035 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0011 | 0.0007 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0036 | 0.1152 |
Plasmodium falciparum | protein kinase 7 | 0.0312 | 0.0537 | 0.1109 |
Plasmodium falciparum | calcium-dependent protein kinase 5 | 0.0034 | 0.0028 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0026 | 0.0022 |
Chlamydia trachomatis | dihydrofolate reductase | 0.5477 | 1 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.5477 | 1 | 1 |
Plasmodium falciparum | calcium-dependent protein kinase 1 | 0.0034 | 0.0028 | 0.0035 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0034 | 0.0028 | 0.0037 |
Toxoplasma gondii | prolyl-tRNA synthetase (ProRS) | 0.0039 | 0.0036 | 0.0054 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0035 | 0.0025 |
Echinococcus granulosus | geminin | 0.0352 | 0.061 | 0.0608 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.0055 | 0.0053 |
Schistosoma mansoni | glucose transport protein | 0.011 | 0.0168 | 0.0165 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0033 | 0.0026 | 0.0022 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.2613 | 0.4752 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0035 | 0.0025 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0038 | 0.0036 | 0.1152 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0023 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0033 | 0.0026 | 0.0054 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0067 | 0.0065 |
Echinococcus granulosus | General substrate transporter | 0.0095 | 0.0139 | 0.0137 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0028 | 0.0878 |
Echinococcus granulosus | glutamyl tRNA synthetase cytoplasmic | 0.0033 | 0.0026 | 0.0024 |
Echinococcus multilocularis | geminin | 0.0352 | 0.061 | 0.0608 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0192 | 0.0317 | 0.0315 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Trypanosoma cruzi | hexose transporter, putative | 0.0034 | 0.0028 | 0.006 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0106 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0042 | 0.0038 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0023 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0035 | 0.1141 |
Trypanosoma brucei | glucose transporter 1E | 0.0034 | 0.0028 | 0.0037 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.011 | 0.0168 | 0.0331 |
Mycobacterium ulcerans | thymidylate synthase | 0.0348 | 0.0603 | 0.0592 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0035 | 0.0074 |
Echinococcus granulosus | thymidylate synthase | 0.0348 | 0.0603 | 0.06 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0035 | 0.0031 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK2B | 0.0034 | 0.0028 | 0.0035 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.5477 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0035 | 0.0074 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0165 | 0.0269 | 0.0265 |
Plasmodium vivax | mitogen-activated protein kinase 2, putative | 0.0178 | 0.0292 | 0.0593 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.2613 | 0.4752 | 1 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.5477 | 1 | 1 |
Onchocerca volvulus | 0.0348 | 0.0603 | 1 | |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0067 | 0.0065 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0077 | 0.0075 |
Trichomonas vaginalis | sugar transporter, putative | 0.0034 | 0.0028 | 0.0878 |
Trichomonas vaginalis | conserved hypothetical protein | 0.011 | 0.0168 | 0.6169 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0035 | 0.0025 |
Plasmodium vivax | CDK-related protein kinase 6, putative | 0.0468 | 0.0823 | 0.1713 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0008 | 0.0006 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.2613 | 0.4752 | 1 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.2613 | 0.4752 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0015 | 0.0011 |
Echinococcus multilocularis | lysyl tRNA synthetase | 0.0025 | 0.0011 | 0.0009 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Entamoeba histolytica | protein kinase, putative | 0.0034 | 0.0028 | 0.6763 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0192 | 0.0317 | 0.0315 |
Brugia malayi | thymidylate synthase | 0.0348 | 0.0603 | 0.0592 |
Trypanosoma brucei | bifunctional aminoacyl-tRNA synthetase, putative | 0.0039 | 0.0036 | 0.0054 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0172 | 0.0281 | 0.0278 |
Entamoeba histolytica | protein kinase, putative | 0.0034 | 0.0028 | 0.6763 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0077 | 0.0075 |
Loa Loa (eye worm) | sugar transporter | 0.011 | 0.0168 | 0.0164 |
Leishmania major | protein kinase, putative | 0.0034 | 0.0028 | 0.0035 |
Echinococcus granulosus | lysyl tRNA synthetase | 0.0025 | 0.0011 | 0.0009 |
Schistosoma mansoni | glucose transport protein | 0.011 | 0.0168 | 0.0165 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0035 | 0.0025 |
Toxoplasma gondii | cell-cycle-associated protein kinase MAPK, putative | 0.0178 | 0.0292 | 0.0593 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0035 | 0.0031 |
Trichomonas vaginalis | glucose transporter, putative | 0.0034 | 0.0028 | 0.0878 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.2613 | 0.4752 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Plasmodium falciparum | proline--tRNA ligase | 0.0039 | 0.0036 | 0.0054 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0035 | 0.0052 |
Mycobacterium leprae | Possible lysyl-tRNA synthetase 2 LysX | 0.0025 | 0.0011 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0028 | 0.0023 |
Brugia malayi | Calcium/calmodulin-dependent protein kinase type II alpha chain | 0.0034 | 0.0028 | 0.0017 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0035 | 0.0033 |
Trypanosoma cruzi | hexose transporter, putative | 0.0034 | 0.0028 | 0.006 |
Leishmania major | glucose transporter, lmgt3 | 0.0034 | 0.0028 | 0.0037 |
Trichomonas vaginalis | sugar transporter, putative | 0.0034 | 0.0028 | 0.0878 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.0055 | 0.0051 |
Schistosoma mansoni | alpha-glucosidase | 0.0148 | 0.0237 | 0.0235 |
Toxoplasma gondii | protein kinase, putative | 0.0312 | 0.0537 | 0.1109 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0037 | 0.0027 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0067 | 0.0063 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0004 | 0.0002 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Schistosoma mansoni | glucose transport protein | 0.011 | 0.0168 | 0.0165 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0035 | 0.0025 |
Echinococcus multilocularis | dihydrofolate reductase | 0.5477 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0036 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0034 | 0.0028 | 0.0878 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0172 | 0.0281 | 0.027 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0301 | 0.0517 | 0.0507 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0038 | 0.0036 | 0.0031 |
Brugia malayi | Sugar transporter family protein | 0.011 | 0.0168 | 0.0157 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0035 | 0.0052 |
Plasmodium vivax | proline--tRNA ligase, putative | 0.0039 | 0.0036 | 0.0054 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0034 | 0.0028 | 0.0848 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0055 | 0.0053 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type 1 | 0.0034 | 0.0028 | 0.0025 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.0055 | 0.0053 |
Trypanosoma brucei | glucose transporter 2A | 0.0034 | 0.0028 | 0.0037 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0035 | 0.1141 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0038 | 0.0036 | 0.0033 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK3 | 0.0034 | 0.0028 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0055 | 0.0051 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0055 | 0.0044 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0035 | 0.0025 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0023 |
Trypanosoma cruzi | hexose transporter, putative | 0.0034 | 0.0028 | 0.006 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0008 | 0.0006 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0055 | 0.0053 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0172 | 0.0281 | 0.0278 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Trypanosoma cruzi | lysyl-tRNA synthetase, putative | 0.0025 | 0.0011 | 0.0023 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0032 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0348 | 0.0603 | 0.06 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0035 | 0.1141 |
Plasmodium falciparum | calcium-dependent protein kinase 4 | 0.0034 | 0.0028 | 0.0035 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.2613 | 0.4752 | 1 |
Plasmodium falciparum | calcium-dependent protein kinase 2 | 0.0034 | 0.0028 | 0.0035 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0012 | 0.0001 |
Leishmania major | glucose transporter, lmgt2 | 0.0034 | 0.0028 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Leishmania major | prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative | 0.0039 | 0.0036 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0067 | 0.0063 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0035 | 0.0025 |
Plasmodium falciparum | calcium-dependent protein kinase 3 | 0.0034 | 0.0028 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0195 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0195 | 0.019 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0165 | 0.0269 | 0.0565 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK2A | 0.0034 | 0.0028 | 0.0035 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.0055 | 0.0053 |
Echinococcus multilocularis | thymidylate synthase | 0.0348 | 0.0603 | 0.06 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Brugia malayi | Cam kinase protein 1 | 0.0034 | 0.0028 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0348 | 0.0603 | 0.0599 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0035 | 0.0033 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0033 | 0.0026 | 0.0032 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0165 | 0.0269 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Loa Loa (eye worm) | zinc finger protein | 0.0301 | 0.0517 | 0.0513 |
Schistosoma mansoni | protein kinase | 0.0034 | 0.0028 | 0.0025 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0035 | 0.1141 |
Schistosoma mansoni | dihydrofolate reductase | 0.5477 | 1 | 1 |
Echinococcus granulosus | dihydrofolate reductase | 0.5477 | 1 | 1 |
Plasmodium vivax | calcium-dependent protein kinase, putative | 0.0034 | 0.0028 | 0.0035 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.0055 | 0.0344 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0023 |
Brugia malayi | Isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0015 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0038 | 0.0036 | 0.0052 |
Trypanosoma cruzi | prolyl-tRNA synthetase, putative | 0.0039 | 0.0036 | 0.0077 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Echinococcus multilocularis | glutamyl tRNA synthetase cytoplasmic | 0.0033 | 0.0026 | 0.0024 |
Schistosoma mansoni | lysyl-tRNA synthetase | 0.0025 | 0.0011 | 0.0009 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0028 | 0.0878 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0033 | 0.0026 | 0.0032 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0168 | 0.0165 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0035 | 0.0031 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0035 | 0.0031 |
Schistosoma mansoni | glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) | 0.0033 | 0.0026 | 0.0024 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0036 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0036 | 0.0075 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0026 | 0.0032 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0348 | 0.0603 | 0.0599 |
Brugia malayi | Bifunctional aminoacyl-tRNA synthetase | 0.0033 | 0.0026 | 0.0016 |
Schistosoma mansoni | glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) | 0.0033 | 0.0026 | 0.0024 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0036 | 0.1152 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0036 | 0.0075 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Leishmania major | prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative | 0.0039 | 0.0036 | 0.0054 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0033 | 0.0031 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0034 | 0.0028 | 0.0025 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0035 | 0.0031 |
Leishmania major | glucose transporter, lmgt1 | 0.0034 | 0.0028 | 0.0037 |
Trypanosoma brucei | glucose transporter, putative | 0.0034 | 0.0028 | 0.0037 |
Trypanosoma brucei | calcium/calmodulin-dependent protein kinase, putative | 0.0034 | 0.0028 | 0.0035 |
Giardia lamblia | Prolyl-tRNA synthetase | 0.0033 | 0.0026 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0026 | 0.0022 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0243 | 0.041 | 0.0407 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.0195 | 0.2809 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0033 | 0.0026 | 0.0023 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0035 | 0.0031 |
Schistosoma mansoni | alpha-glucosidase | 0.0148 | 0.0237 | 0.0235 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0033 | 0.0026 | 0.0022 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0036 | 0.1152 |
Echinococcus granulosus | zinc finger transcription factor gli2 | 0.0301 | 0.0517 | 0.0515 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.011 | 0.0168 | 0.0165 |
Plasmodium vivax | calcium-dependent protein kinase 3, putative | 0.0034 | 0.0028 | 0.0035 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0036 | 0.1152 |
Plasmodium vivax | calcium-dependent protein kinase 4, putative | 0.0034 | 0.0028 | 0.0035 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0038 | 0.0036 | 0.0025 |
Trypanosoma cruzi | prolyl-tRNA synthetase, putative | 0.0039 | 0.0036 | 0.0077 |
Schistosoma mansoni | protein kinase | 0.0034 | 0.0028 | 0.0025 |
Trypanosoma brucei | glucosidase, putative | 0.0038 | 0.0036 | 0.0052 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0035 | 0.0031 |
Loa Loa (eye worm) | thymidylate synthase | 0.0348 | 0.0603 | 0.0598 |
Onchocerca volvulus | 0.0099 | 0.0148 | 0.1985 | |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0038 | 0.0036 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0352 | 0.061 | 0.0608 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.0195 | 0.2809 |
Plasmodium vivax | hexose transporter | 0.011 | 0.0168 | 0.0331 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0035 | 0.0052 |
Mycobacterium leprae | Probable prolyl tRNA synthetase ProS | 0.0033 | 0.0026 | 0.0022 |
Schistosoma mansoni | protein kinase | 0.0034 | 0.0028 | 0.0025 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0035 | 0.0031 |
Loa Loa (eye worm) | calcium/calmodulin-dependent protein kinase ID | 0.0034 | 0.0028 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0165 | 0.0269 | 0.0258 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0035 | 0.0033 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0036 | 0.1152 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0067 | 0.0056 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0035 | 0.0031 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0034 | 0.0028 | 0.0025 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Binding (binding) | = 46 % | Compound was tested for human IgG protein binding at 1 mg/mL | ChEMBL. | 3761302 |
Binding (binding) | = 69.5 % | Compound was tested for human IgG protein binding at 100 ug/mL | ChEMBL. | 3761302 |
Stability (functional) | = 91 % | Compound was tested for human IgG protein stability at 100 ug/mL | ChEMBL. | 3761302 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.