Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0815 | 0.0017 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0815 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0815 | 0.0815 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0815 | 0.5 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0815 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.2521 | 0.1872 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0815 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.8356 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0815 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0815 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.097 | 0.097 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1285 | 0.0512 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0815 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.3319 | 0.2727 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0815 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0159 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.2521 | 0.1872 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0815 | 0.5 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0815 | 0.0017 |
Onchocerca volvulus | 0.0092 | 0.5023 | 0.5 | |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0815 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0815 | 0.5 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0815 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0815 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 1 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.278 | 0.2606 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.8356 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0159 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1147 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0975 | 0.0175 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0815 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.3629 | 0.3629 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0815 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0815 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.