Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.011 | 0.951 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.011 | 0.951 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0914 | 0.0961 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.011 | 0.951 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0914 | 0.0961 |
Onchocerca volvulus | 0.0015 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0914 | 0.0914 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0914 | 0.0961 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.011 | 0.951 | 0.951 |
Trichomonas vaginalis | immunophilin, putative | 0.011 | 0.951 | 1 |
Schistosoma mansoni | immunophilin | 0.011 | 0.951 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.011 | 0.951 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0914 | 1 |
Schistosoma mansoni | immunophilin | 0.0095 | 0.7992 | 0.8404 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0914 | 0.0961 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.011 | 0.951 | 0.951 |
Onchocerca volvulus | 0.0015 | 0 | 0.5 | |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.011 | 0.951 | 1 |
Echinococcus multilocularis | fk506 binding protein | 0.011 | 0.951 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0095 | 0.7992 | 0.8404 |
Schistosoma mansoni | immunophilin | 0.011 | 0.951 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0115 | 1 | 1 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.011 | 0.951 | 1 |
Loa Loa (eye worm) | FKBP5 protein | 0.011 | 0.951 | 0.951 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.011 | 0.951 | 1 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.011 | 0.951 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.011 | 0.951 | 1 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.011 | 0.951 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.011 | 0.951 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0914 | 0.0961 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.011 | 0.951 | 1 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.0015 | 0 | 0.5 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0095 | 0.7992 | 0.8404 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.011 | 0.951 | 1 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.0015 | 0 | 0.5 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.011 | 0.951 | 1 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.011 | 0.951 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0115 | 1 | 1 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.011 | 0.951 | 1 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0914 | 0.0914 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0015 | 0 | 0.5 |
Leishmania major | fk506-binding protein 1-like protein | 0.011 | 0.951 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.011 | 0.951 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.7992 | 0.7992 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.011 | 0.951 | 1 |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.0015 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0914 | 0.0961 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.011 | 0.951 | 1 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.011 | 0.951 | 1 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.011 | 0.951 | 1 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0015 | 0 | 0.5 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.011 | 0.951 | 0.951 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0052 | 0.0052 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0914 | 0.0961 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.011 | 0.951 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.