Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.5662 | 0.718 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.2951 | 0.4076 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.2951 | 0.4076 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.5662 | 0.6054 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0535 | 0.0739 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.5662 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.5662 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3818 | 0.4014 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.5662 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.9228 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.5662 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.5662 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3391 | 0.3541 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.5662 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.5662 | 0.5 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.5662 | 0.52 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0191 | 0.0242 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0535 | 0.0739 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.3378 | 0.2673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.724 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.5662 | 0.782 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4163 | 0.4395 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0535 | 0.0679 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.5662 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.7886 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.5662 | 0.782 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.5662 | 0.782 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.5662 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.724 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.5662 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.5662 | 0.782 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.