Detailed information for compound 776700

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 279.398 | Formula: C15H21NO2S
  • H donors: 1 H acceptors: 2 LogP: 1.93 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCN1CCCC(C1)C(=O)c1ccc(cc1)SC
  • InChi: 1S/C15H21NO2S/c1-19-14-6-4-12(5-7-14)15(18)13-3-2-8-16(11-13)9-10-17/h4-7,13,17H,2-3,8-11H2,1H3
  • InChiKey: UAGLCRMHCMPKGE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ABC1 family protein 0.0071 0.1366 0.9804
Loa Loa (eye worm) RNA binding protein 0.0191 0.4064 0.6921
Brugia malayi TAR-binding protein 0.0191 0.4064 0.6921
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0395 0.0673
Onchocerca volvulus 0.0071 0.1366 0.5458
Schistosoma mansoni cpg binding protein 0.0029 0.0442 0.0508
Echinococcus granulosus inositol monophosphatase 1 0.0072 0.1393 0.1393
Leishmania major cytochrome p450-like protein 0.0019 0.0208 0.1405
Echinococcus multilocularis expressed protein 0.0017 0.0151 0.0151
Onchocerca volvulus 0.002 0.0221 0.0881
Onchocerca volvulus 0.002 0.0221 0.0881
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.1366 0.1365
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0072 0.1393 0.2353
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.1393 1
Brugia malayi Latrophilin receptor protein 2 0.0079 0.1557 0.2651
Loa Loa (eye worm) DR-78 0.002 0.0221 0.0376
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.4909 0.564
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0221 0.0376
Schistosoma mansoni ferritin 0.0017 0.0151 0.0174
Mycobacterium ulcerans lipase LipD 0.0071 0.1366 0.2307
Plasmodium vivax hypothetical protein, conserved 0.0071 0.1366 1
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0714 0.1217
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0714 0.0821
Brugia malayi nuclear receptor NHR-88 0.002 0.0221 0.0376
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0714 0.1217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0714 0.1217
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1366 0.2326
Schistosoma mansoni hypothetical protein 0.001 0.0014 0.0016
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0714 0.2855
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0072 0.1393 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0714 0.1217
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0714 0.0714
Echinococcus multilocularis neuropeptide s receptor 0.0455 1 1
Mycobacterium ulcerans hypothetical protein 0.0071 0.1366 0.2307
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0208 0.0354
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Brugia malayi CXXC zinc finger family protein 0.0028 0.0406 0.0692
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.4909 0.564
Brugia malayi Inositol-1 0.0072 0.1393 0.2372
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0714 0.1217
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Echinococcus multilocularis geminin 0.0343 0.7481 0.7481
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.4909 0.4909
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0221 0.0376
Trichomonas vaginalis glutaminase, putative 0.0271 0.5872 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0714 0.0821
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0714 0.1217
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.1105 0.1101
Schistosoma mansoni cpg binding protein 0.0028 0.0406 0.0467
Schistosoma mansoni hypothetical protein 0.0397 0.8705 1
Schistosoma mansoni inositol monophosphatase 0.0072 0.1393 0.16
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0714 0.0821
Onchocerca volvulus Huntingtin homolog 0.0121 0.2503 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1366 0.1569
Loa Loa (eye worm) hypothetical protein 0.0071 0.1366 0.2326
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.1366 0.1365
Brugia malayi hypothetical protein 0.002 0.0221 0.0376
Brugia malayi conserved hypotetical protein 0.002 0.0221 0.0376
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0273 0.0273
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1366 0.1569
Mycobacterium leprae conserved hypothetical protein 0.0071 0.1366 1
Echinococcus granulosus tar DNA binding protein 0.0191 0.4064 0.4064
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0064 0.1224 0.8949
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0221 0.0253
Loa Loa (eye worm) pigment dispersing factor receptor c 0.025 0.5397 0.919
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0714 0.1217
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0714 0.1217
Schistosoma mansoni lamin 0.0027 0.0395 0.0454
Echinococcus granulosus expressed protein 0.0017 0.0151 0.0151
Brugia malayi nuclear receptor NHR-67 0.002 0.0221 0.0376
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0714 0.1217
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1366 0.2326
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0221 0.0376
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0064 0.1224 0.1222
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.1105 0.1269
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0359 0.2503
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.0071 0.1366 0.2326
Leishmania major hypothetical protein, conserved 0.0026 0.0359 0.2503
Echinococcus granulosus neuropeptide receptor A26 0.0455 1 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0714 0.0714
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0208 0.0354
Echinococcus multilocularis musashi 0.0027 0.0395 0.0395
Loa Loa (eye worm) cytochrome P450 0.001 0.0014 0.0024
Loa Loa (eye worm) hypothetical protein 0.025 0.5397 0.919
Brugia malayi tailless protein 0.002 0.0221 0.0376
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0359 0.5
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0221 0.0253
Loa Loa (eye worm) hypothetical protein 0.0022 0.0273 0.0466
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0406 0.0692
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0714 0.0821
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.4909 0.4909
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0714 0.1217
Loa Loa (eye worm) hypothetical protein 0.0022 0.0273 0.0466
Loa Loa (eye worm) hypothetical protein 0.0071 0.1366 0.2326
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0714 0.0714
Brugia malayi RNA binding protein 0.0191 0.4064 0.6921
Onchocerca volvulus 0.0071 0.1366 0.5458
Brugia malayi hypothetical protein 0.0022 0.0273 0.0466
Schistosoma mansoni zinc finger protein 0.002 0.0221 0.0253
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0714 0.0714
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.1105 0.1105
Echinococcus multilocularis 0.001 0.0014 0.0014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.1557 0.1557
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0221 0.0376
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.1393 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0151 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0714 0.1217
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0151 0.1014
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0221 0.0221
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.4909 0.4909
Echinococcus granulosus GPCR family 2 0.0079 0.1557 0.1557
Echinococcus granulosus cpg binding protein 0.0029 0.0442 0.0442
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0077 0.0077
Mycobacterium leprae Probable lipase LipE 0.0071 0.1366 1
Schistosoma mansoni hypothetical protein 0.0171 0.362 0.4158
Echinococcus granulosus ferritin 0.0017 0.0151 0.0151
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0273 0.0273
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0714 0.0714
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1366 0.9804
Brugia malayi hypothetical protein 0.0026 0.0359 0.0612
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0151 0.0138
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.1557 0.1557
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0714 0.1217
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0714 0.0821
Schistosoma mansoni hypothetical protein 0.0343 0.7481 0.8593
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.1393 0.2372
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0221 0.0221
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.1557 0.1557
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.8705 0.8705
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.025 0.5397 0.919
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0208 0.0331
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0714 0.0714
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0121 0.2503 0.4262
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0221 0.0221
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0714 0.0714
Echinococcus granulosus cytochrome P450 2K1 0.001 0.0014 0.0014
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0714 0.0714
Brugia malayi intermediate filament protein 0.0027 0.0395 0.0673
Mycobacterium tuberculosis Conserved protein 0.0071 0.1366 0.1365
Schistosoma mansoni glutaminase 0.0271 0.5872 0.6746
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0714 0.1217
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.1105 0.1861
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0714 0.1217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0714 0.1217
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0221 0.0881
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.1366 0.1365
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0714 0.0714
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0967 0.691
Echinococcus multilocularis inositol monophosphatase 1 0.0072 0.1393 0.1393
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0714 0.1217
Brugia malayi ecdysone receptor 0.002 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.0022 0.0273 0.0466
Echinococcus multilocularis GPCR, family 2 0.0079 0.1557 0.1557
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Loa Loa (eye worm) TAR-binding protein 0.0191 0.4064 0.6921
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.1105 0.1269
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0359 0.2503
Brugia malayi Cytochrome P450 family protein 0.001 0.0014 0.0024
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.1366 0.1366
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Brugia malayi Cytochrome P450 family protein 0.0029 0.0436 0.0742
Schistosoma mansoni tar DNA-binding protein 0.0191 0.4064 0.4668
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0714 0.2855
Mycobacterium ulcerans beta-lactamase 0.0071 0.1366 0.2307
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1366 0.9804
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0208 0.1405
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0359 0.2503
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0714 0.0821
Loa Loa (eye worm) hypothetical protein 0.0071 0.1366 0.2326
Loa Loa (eye worm) hypothetical protein 0.0022 0.0273 0.0466
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0273 0.0466
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.1366 0.1365
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.1557 0.1557
Schistosoma mansoni tar DNA-binding protein 0.0191 0.4064 0.4668
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0451 0.9914 1
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0714 0.0821
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.1366 0.1365
Schistosoma mansoni nuclear hormone receptor 0.002 0.0221 0.0253
Loa Loa (eye worm) hypothetical protein 0.0027 0.0384 0.0654
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.004 0.004
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0208 0.0354
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.4909 0.4909
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.1366 0.2307
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.0121 0.2503 0.4262
Brugia malayi nuclear receptor RXR 0.0022 0.0273 0.0466
Mycobacterium ulcerans glutaminase 0.0271 0.5872 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Schistosoma mansoni tar DNA-binding protein 0.0191 0.4064 0.4668
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0714 0.0821
Brugia malayi Calcitonin receptor-like protein seb-1 0.025 0.5397 0.919
Echinococcus granulosus dnaJ subfamily B 0.0397 0.8705 0.8705
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0714 0.0714
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0151 0.0234
Schistosoma mansoni nuclear receptor 0.002 0.0221 0.0253
Schistosoma mansoni cpg binding protein 0.0029 0.0442 0.0508
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.1557 0.2651
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0273 0.0466
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0071 0.1366 0.2326
Echinococcus multilocularis tar DNA binding protein 0.0191 0.4064 0.4064
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0714 0.1217
Loa Loa (eye worm) glutaminase 0.0271 0.5872 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0077 0.0131
Schistosoma mansoni hypothetical protein 0.0079 0.1557 0.1789
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1366 0.2326
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Echinococcus granulosus intermediate filament protein 0.0027 0.0395 0.0395
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.1393 0.2372
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0714 0.1217
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.4909 0.836
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0208 0.1405
Schistosoma mansoni intermediate filament proteins 0.0027 0.0395 0.0454
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1366 0.2326
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0151 0.5
Brugia malayi hypothetical protein 0.0017 0.0154 0.0262
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0714 0.0714
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0221 0.0221
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.1366 0.1365
Schistosoma mansoni apoferritin-2 0.0017 0.0151 0.0174
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0359 0.5
Schistosoma mansoni hypothetical protein 0.0079 0.1557 0.1789
Brugia malayi nuclear receptor NHR-88 0.0042 0.0714 0.1217
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0273 0.0466
Schistosoma mansoni ferritin light chain 0.0017 0.0151 0.0174
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0714 0.2855
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0273 0.0314
Brugia malayi hypothetical protein 0.0022 0.0273 0.0466
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.011 0.0186
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0714 0.0821
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0714 0.0821
Schistosoma mansoni tar DNA-binding protein 0.0191 0.4064 0.4668
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Echinococcus multilocularis lamin 0.0027 0.0395 0.0395
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0714 0.0821
Schistosoma mansoni tar DNA-binding protein 0.0191 0.4064 0.4668
Onchocerca volvulus 0.0042 0.0714 0.2855
Brugia malayi hypothetical protein 0.002 0.0221 0.0376
Brugia malayi Nuclear hormone receptor E75 0.002 0.0221 0.0376
Onchocerca volvulus 0.0027 0.0395 0.158
Brugia malayi hypothetical protein 0.0121 0.2503 0.4262
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.1366 0.2326
Brugia malayi Cytochrome P450 family protein 0.0019 0.0208 0.0354
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.1366 0.1366
Onchocerca volvulus 0.0071 0.1366 0.5458
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0221 0.0221
Trichomonas vaginalis ferritin, putative 0.0017 0.0151 0.0258
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0077 0.0077
Echinococcus multilocularis lamin dm0 0.0027 0.0395 0.0395
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.4064 0.6921
Schistosoma mansoni ferritin 0.0017 0.0151 0.0174
Loa Loa (eye worm) beta-lactamase 0.0071 0.1366 0.2326
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.1393 1
Schistosoma mansoni nuclear receptor 0.002 0.0221 0.0253
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0395 0.0673
Mycobacterium tuberculosis Conserved protein 0.0071 0.1366 0.1365
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Schistosoma mansoni ferritin 0.0017 0.0151 0.0174
Schistosoma mansoni ferritin light chain 0.0017 0.0151 0.0174
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0221 0.0221
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0395 0.0673
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.011 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0714 0.1217
Loa Loa (eye worm) hypothetical protein 0.0042 0.0714 0.1217
Brugia malayi beta-lactamase 0.0071 0.1366 0.2326
Echinococcus granulosus lamin 0.0027 0.0395 0.0395
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1109 0.1274
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.1105 0.7909
Schistosoma mansoni coup transcription factor 0.0042 0.0714 0.0821
Loa Loa (eye worm) hypothetical protein 0.0079 0.1557 0.2651
Schistosoma mansoni apoferritin-2 0.0017 0.0151 0.0174
Onchocerca volvulus 0.0027 0.0395 0.158
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0151 0.0234
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.4909 0.564
Loa Loa (eye worm) hypothetical protein 0.0027 0.0395 0.0673
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0208 0.1405
Loa Loa (eye worm) hypothetical protein 0.0022 0.0273 0.0466
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0221 0.0376
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0714 0.1217
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0714 0.0821
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0221 0.0221
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.1366 0.2307
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0221 0.0221
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.4909 0.836
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1366 0.2326
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.1105 0.1105
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0714 0.1217
Loa Loa (eye worm) glutaminase 2 0.0271 0.5872 1
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.4064 0.6921
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0072 0.1393 1
Schistosoma mansoni nuclear hormone receptor 0.002 0.0221 0.0253
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.004 0.004
Brugia malayi cytochrome P450 0.001 0.0014 0.0024
Echinococcus multilocularis neuropeptide receptor A26 0.0455 1 1
Echinococcus multilocularis cpg binding protein 0.0029 0.0442 0.0442
Schistosoma mansoni hypothetical protein 0.0079 0.1557 0.1789
Brugia malayi steroid hormone receptor 0.0042 0.0714 0.1217
Loa Loa (eye worm) hypothetical protein 0.0071 0.1366 0.2326
Schistosoma mansoni inositol monophosphatase 0.0072 0.1393 0.16
Onchocerca volvulus Huntingtin homolog 0.0121 0.2503 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.1105 0.1861
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0714 0.1217
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0714 0.1217
Echinococcus granulosus lamin dm0 0.0027 0.0395 0.0395
Schistosoma mansoni cytochrome P450 0.001 0.0014 0.0016
Brugia malayi glutaminase DH11.1 0.0271 0.5872 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0221 0.0221
Loa Loa (eye worm) inositol-1 0.0072 0.1393 0.2372
Schistosoma mansoni ferritin 0.0017 0.0151 0.0174
Brugia malayi beta-lactamase family protein 0.0071 0.1366 0.2326
Leishmania major hypothetical protein, conserved 0.0071 0.1366 0.9804
Brugia malayi nuclear hormone receptor 0.0042 0.0714 0.1217
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.1105 0.7909
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0436 0.0742
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.1366 0.9804
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0221 0.0376
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.1366 0.2326
Loa Loa (eye worm) hypothetical protein 0.0026 0.0359 0.0612
Brugia malayi Nuclear hormone receptor E75 0.002 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.0013 0.0066 0.0112
Mycobacterium tuberculosis Conserved protein 0.0071 0.1366 0.1365
Brugia malayi beta-lactamase family protein 0.0071 0.1366 0.2326
Brugia malayi nuclear receptor RXR 0.002 0.0221 0.0376
Trichomonas vaginalis inositol monophosphatase, putative 0.0072 0.1393 0.2372
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.1557 0.2651
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0714 0.0714
Schistosoma mansoni hypothetical protein 0.0079 0.1557 0.1789
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0072 0.1393 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.1366 0.1365
Loa Loa (eye worm) hypothetical protein 0.0013 0.0066 0.0112
Schistosoma mansoni hypothetical protein 0.0012 0.004 0.0046
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.1393 1
Loa Loa (eye worm) hypothetical protein 0.0171 0.362 0.6164
Onchocerca volvulus 0.0028 0.0406 0.1624
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0359 0.2503
Schistosoma mansoni lamin 0.0027 0.0395 0.0454
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0273 0.0314
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0221 0.0881
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.362 0.6164
Echinococcus granulosus geminin 0.0343 0.7481 0.7481
Schistosoma mansoni hypothetical protein 0.0343 0.7481 0.8593
Echinococcus multilocularis ferritin 0.0017 0.0151 0.0151
Trichomonas vaginalis esterase, putative 0.0071 0.1366 0.2326
Brugia malayi Cytochrome P450 family protein 0.0019 0.0208 0.0354
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0714 0.0714
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0714 0.0714
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.002 0.0221 0.0376
Brugia malayi ecdysteroid receptor 0.0042 0.0714 0.1217
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0221 0.0253
Brugia malayi nuclear hormone receptor 0.002 0.0221 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0714 0.1217
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0221 0.0221
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.1105 0.1861

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.