Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.8246 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.8246 | 0.8246 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.8246 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.4623 | 0.0624 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.4623 | 0.4623 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.8246 | 0.8246 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.4623 | 0.4623 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.4623 | 0.0624 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.4266 | 0.4266 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.8246 | 0.8246 |
Brugia malayi | TAR-binding protein | 0.0066 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.