Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0071 | 0.0071 |
Schistosoma mansoni | transmemberane protein | 0.007 | 0.1752 | 0.1688 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0046 | 0.1005 | 0.0789 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0658 | 0.0598 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1122 | 0.1065 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.0046 | 0.1005 | 0.094 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0046 | 0.1005 | 0.0848 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0195 | 0.0132 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0658 | 0.03 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0407 | 0.0346 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0256 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0071 | 0.0071 |
Trichomonas vaginalis | set domain proteins, putative | 0.0229 | 0.6827 | 1 |
Leishmania major | P-type ATPase, putative | 0.0037 | 0.071 | 0.0465 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0658 | 0.0598 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 1 |
Brugia malayi | hypothetical protein | 0.0157 | 0.4508 | 0.4473 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0446 | 0.0371 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0195 | 0.0132 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.2185 | 0.2152 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0071 | 0.0071 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0195 | 0.0119 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.016 | 0.4628 | 0.4586 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0195 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0077 | 0.0077 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0784 | 0.7345 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0195 | 0.0195 |
Leishmania major | P-type H -ATPase, putative | 0.003 | 0.0467 | 0.0216 |
Trypanosoma cruzi | calcium-translocating P-type ATPase, putative | 0.002 | 0.0172 | 0.0109 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0446 | 0.0371 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0784 | 0.0712 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0125 | 0.3517 | 0.3466 |
Trypanosoma brucei | P-type H+-ATPase, putative | 0.003 | 0.0467 | 0.0238 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.2185 | 0.2152 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0077 | 0.0014 |
Schistosoma mansoni | lamin | 0.0026 | 0.0357 | 0.0282 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.0691 | 0.0624 |
Trichomonas vaginalis | cation-transporting ATPase fungi, putative | 0.0046 | 0.1005 | 0.0846 |
Echinococcus granulosus | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Entamoeba histolytica | calcium-transporting P-type ATPase, putative | 0.0046 | 0.1005 | 1 |
Onchocerca volvulus | 0.0029 | 0.0446 | 0.0256 | |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0691 | 0.0467 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0259 | 0.0259 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0658 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.0691 | 0.0624 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0195 | 0.0195 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0195 | 0.0119 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.3362 | 0.3231 |
Giardia lamblia | Plasma membrane calcium-transporting ATPase 2 | 0.0046 | 0.1005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0235 | 0.0235 |
Leishmania major | calcium-translocating P-type ATPase | 0.0046 | 0.1005 | 0.0769 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0195 | 0.0119 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0157 | 0.4508 | 0.4473 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0256 | 0.0186 |
Entamoeba histolytica | plasma membrane calcium-transporting ATPase 1, putative | 0.0026 | 0.0359 | 0.2249 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0195 | 0.0119 |
Toxoplasma gondii | P-type ATPase PMA1 | 0.003 | 0.0467 | 0.0301 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0784 | 0.7345 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.3466 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.2482 | 0.2451 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0407 | 0.0176 |
Toxoplasma gondii | calcium-translocating P-type ATPase, PMCA-type protein | 0.0046 | 0.1005 | 0.0848 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0329 | 1 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0046 | 0.1005 | 0.0948 |
Echinococcus multilocularis | calcium transporting atpase | 0.0037 | 0.071 | 0.0637 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0037 | 0.071 | 0.0637 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0071 | 0.003 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Leishmania major | P-type H -ATPase, putative | 0.003 | 0.0467 | 0.0216 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0046 | 0.1005 | 0.0935 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0046 | 0.1005 | 0.0935 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0407 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Trypanosoma brucei | calcium-translocating P-type ATPase | 0.0037 | 0.071 | 0.0486 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0784 | 0.0712 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0032 | 0.0531 | 0.0531 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0046 | 0.1005 | 0.0935 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0691 | 0.0632 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha chain, putative | 0.0032 | 0.0531 | 0.047 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.0691 | 0.0624 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0037 | 0.071 | 0.0637 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0658 | 0.0658 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0037 | 0.071 | 0.0637 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0256 | 0.0186 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.2185 | 0.2152 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0172 | 0.0172 |
Trypanosoma cruzi | calcium-transporting ATPase, putative | 0.0022 | 0.0235 | 0.0173 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0195 | 0.0119 |
Echinococcus multilocularis | sarco:endoplasmic reticulum calcium ATPase | 0.0046 | 0.1005 | 0.0935 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0658 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0407 | 0.0407 |
Mycobacterium tuberculosis | Possible metal cation transporting P-type ATPase CtpH | 0.0032 | 0.0531 | 0.0491 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0195 | 0.0119 |
Brugia malayi | Probable calcium-transporting ATPase KIAA0703 | 0.0022 | 0.0235 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1005 | 0.1005 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1122 | 0.1053 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.347 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0195 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.4508 | 0.6355 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0195 | 0.0119 |
Leishmania major | calcium motive p-type ATPase, putative | 0.0037 | 0.071 | 0.0465 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0717 | 0.0717 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0446 | 0.0371 |
Toxoplasma gondii | plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 | 0.0037 | 0.071 | 0.0548 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.007 | 0.1752 | 0.1688 |
Echinococcus granulosus | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.016 | 0.4628 | 0.4628 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0691 | 0.0652 |
Echinococcus multilocularis | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.2482 | 0.2284 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha-3 chain, putative | 0.002 | 0.0172 | 0.0109 |
Leishmania major | calcium-transporting ATPase, putative | 0.0037 | 0.071 | 0.0465 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0707 | 0.0635 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0446 | 0.0371 |
Schistosoma mansoni | lamin | 0.0026 | 0.0357 | 0.0282 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0446 | 0.0279 |
Echinococcus granulosus | calcium transporting atpase | 0.0037 | 0.071 | 0.0637 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1122 | 0.1122 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0784 | 0.7345 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0046 | 0.1005 | 0.0948 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.2185 | 0.2152 |
Plasmodium falciparum | calcium-transporting ATPase | 0.0037 | 0.071 | 0.0643 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0195 | 0.0132 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.2185 | 0.2152 |
Echinococcus granulosus | lamin | 0.0026 | 0.0357 | 0.0282 |
Loa Loa (eye worm) | sodium potassium adenosine triphosphatase | 0.002 | 0.0172 | 0.0172 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0256 | 0.0186 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.349 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0256 | 0.0186 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0357 | 0.0357 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.347 |
Brugia malayi | Membrane calcium atpase protein 3 | 0.0037 | 0.071 | 0.065 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase F, CtpF | 0.0046 | 0.1005 | 0.094 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0071 | 0.0071 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0407 | 0.0346 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0784 | 0.7345 |
Brugia malayi | E1-E2 ATPase family protein | 0.003 | 0.0467 | 0.0406 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0195 | 0.0119 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0658 | 0.5832 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0256 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1005 | 0.1005 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0357 | 0.0357 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Echinococcus granulosus | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0691 | 0.0632 |
Brugia malayi | hypothetical protein | 0.004 | 0.0784 | 0.0725 |
Entamoeba histolytica | plasma membrane calcium ion-transporting ATPase, putative | 0.0026 | 0.0359 | 0.2249 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0357 | 0.0295 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.016 | 0.4628 | 0.4594 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0195 | 0.0132 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0658 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0195 | 0.0132 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0707 | 0.0635 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0658 | 0.03 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0195 | 0.0119 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0032 | 0.0531 | 0.0282 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0658 | 0.03 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0195 | 0.0132 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0717 | 0.0658 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0195 | 0.0132 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0195 | 0.0132 |
Trypanosoma brucei | P-type H+-ATPase, putative | 0.003 | 0.0467 | 0.0238 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0329 | 1 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0329 | 1 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0658 | 0.0433 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 1 |
Trypanosoma cruzi | plasma-membrane proton-efflux P-type ATPase, putative | 0.002 | 0.0172 | 0.0109 |
Plasmodium vivax | calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 0.094 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0357 | 0.0282 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0195 | 0.0119 |
Loa Loa (eye worm) | calcium ATPase | 0.0026 | 0.0359 | 0.0359 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1122 | 0.1053 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0195 | 0.0119 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.007 | 0.1752 | 0.1688 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0407 | 0.0338 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0658 | 0.0495 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0446 | 0.0384 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0259 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1752 | 0.1752 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0195 | 0.0119 |
Onchocerca volvulus | 0.0026 | 0.0357 | 0.0165 | |
Schistosoma mansoni | calcium-transporting atpase 2 (atpase 2) | 0.0037 | 0.071 | 0.0637 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0691 | 0.0632 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0195 | 0.0132 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0195 | 0.0119 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0195 | 0.0119 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0046 | 0.1005 | 0.0948 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0691 | 0.0691 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0357 | 0.0282 |
Schistosoma mansoni | ATPase | 0.0046 | 0.1005 | 0.0935 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0195 | 0.0132 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0195 | 0.0132 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0195 | 0.0195 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0125 | 0.3517 | 0.3346 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0195 | 0.0132 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0195 | 0.0119 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0046 | 0.1005 | 0.0935 |
Brugia malayi | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0037 | 0.071 | 0.065 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0195 | 0.0119 |
Echinococcus multilocularis | Ca2+ transporting ATPase plasma membrane | 0.0037 | 0.071 | 0.0637 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0195 | 0.0119 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0784 | 0.0712 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.347 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0256 | 0.1015 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0195 | 0.0119 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0046 | 0.1005 | 0.0769 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0658 | 0.0585 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.2482 | 0.2451 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0329 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0717 | 0.0645 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0691 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Echinococcus multilocularis | plasma membrane calcium transporting ATPase | 0.0037 | 0.071 | 0.0637 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0095 | 0.0031 |
Onchocerca volvulus | 0.0046 | 0.1005 | 0.0827 | |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.002 | 0.0172 | 0.0109 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0256 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.007 | 0.1752 | 0.1688 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.1269 | 0.1213 |
Onchocerca volvulus | 0.0026 | 0.0357 | 0.0165 | |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.3362 | 0.3231 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0046 | 0.1005 | 0.094 |
Echinococcus multilocularis | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0195 | 0.0119 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0195 | 0.0132 |
Trypanosoma brucei | calcium motive p-type ATPase, putative | 0.0037 | 0.071 | 0.0486 |
Echinococcus multilocularis | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0195 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0195 | 0.0132 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0357 | 0.0282 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.1269 | 0.1269 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.594 | 0.594 |
Brugia malayi | haloacid dehalogenase-like hydrolase family protein | 0.0026 | 0.0359 | 0.0297 |
Echinococcus granulosus | Ca2 transporting ATPase plasma membrane | 0.0037 | 0.071 | 0.0637 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0256 | 0.0186 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.594 | 0.5915 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0195 | 0.0119 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0407 | 0.0155 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1122 | 0.1053 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1122 | 0.1053 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0046 | 0.1005 | 0.1005 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0256 | 0.0194 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0256 | 0.1015 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Schistosoma mansoni | ATPase | 0.0046 | 0.1005 | 0.0935 |
Loa Loa (eye worm) | calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0022 | 0.0235 | 0.0235 |
Brugia malayi | calcium ATPase | 0.002 | 0.0172 | 0.0109 |
Schistosoma mansoni | na+/k+ atpase alpha subunit | 0.0037 | 0.071 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0256 | 0.0256 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0084 | 0.2185 | 0.198 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.0691 | 0.0529 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0329 | 1 | 1 |
Toxoplasma gondii | P-type ATPase4, putative | 0.0046 | 0.1005 | 0.0848 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0658 | 0.0585 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0195 | 0.0119 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0037 | 0.071 | 0.065 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.3466 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0256 | 0.0194 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0658 | 0.03 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0256 | 0.0215 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0784 | 0.0712 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0407 | 0.024 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.003 | 0.0467 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0256 | 0.0256 |
Onchocerca volvulus | 0.0093 | 0.2477 | 0.2327 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1122 | 0.1053 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0195 | 0.0195 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0412 | 0.0337 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0195 | 0.0195 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0046 | 0.1005 | 0.0789 |
Plasmodium vivax | P-type ATPase4, putative | 0.0046 | 0.1005 | 0.094 |
Echinococcus multilocularis | Na+:K+ ATPase alpha subunit | 0.0037 | 0.071 | 0.0637 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0046 | 0.1005 | 0.0769 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0195 | 0.0195 |
Brugia malayi | hypothetical protein | 0.0121 | 0.3362 | 0.332 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0446 | 0.0371 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0195 | 0.0119 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0195 | 0.0119 |
Onchocerca volvulus | 0.0023 | 0.0256 | 0.0063 | |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0658 | 0.5832 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1752 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1269 | 0.1269 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0446 | 0.0377 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.2482 | 0.2451 |
Echinococcus granulosus | sarco:endoplasmic reticulum calcium ATPase | 0.0046 | 0.1005 | 0.0935 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.3918 | 0.387 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0195 | 0.0119 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0256 | 0.0215 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0658 | 0.0585 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0195 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0195 | 0.0132 |
Onchocerca volvulus | 0.0329 | 1 | 1 | |
Mycobacterium ulcerans | cation-transporter ATPase I CtpI | 0.0032 | 0.0531 | 0.0462 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0658 | 0.03 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0407 | 0.0338 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase | 0.0037 | 0.071 | 0.0637 |
Echinococcus granulosus | Na:K ATPase alpha subunit | 0.0037 | 0.071 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.3362 | 0.3362 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.003 | 0.0467 | 0.0406 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.3362 | 0.3362 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0195 | 0.0119 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.2185 | 0.2152 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0046 | 0.1005 | 0.0935 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0077 | 0.0014 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0195 | 0.0119 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0329 | 1 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0446 | 0.0371 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.1269 | 0.1213 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1122 | 0.1053 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.3918 | 0.387 |
Loa Loa (eye worm) | thymidylate synthase | 0.0329 | 1 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0329 | 1 | 1 |
Echinococcus granulosus | thymidylate synthase | 0.0329 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0256 | 0.0194 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0256 | 0.1015 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0329 | 1 | 1 |
Onchocerca volvulus | 0.0229 | 0.6827 | 0.6764 | |
Echinococcus granulosus | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0195 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.4628 | 0.4586 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0125 | 0.3517 | 0.3403 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0357 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0064 | 0.0064 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0407 | 0.0338 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0446 | 0.0371 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0195 | 0.0132 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0195 | 0.0132 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0691 | 0.0691 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0357 | 0.0282 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Echinococcus multilocularis | nervana 2 | 0.007 | 0.1752 | 0.1688 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0658 | 0.03 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0157 | 0.4508 | 0.4486 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0046 | 0.1005 | 0.0789 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0037 | 0.071 | 0.0382 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0125 | 0.3517 | 0.3466 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0071 | 0.5 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Loa Loa (eye worm) | E1-E2 ATPase | 0.003 | 0.0467 | 0.0467 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0658 | 0.03 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0195 | 0.0195 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0658 | 0.0598 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0195 | 0.0132 |
Echinococcus multilocularis | thymidylate synthase | 0.0329 | 1 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0329 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0357 | 0.0282 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.4628 | 0.4586 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.0691 | 0.0624 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0195 | 0.0132 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0046 | 0.1005 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0446 | 0.0446 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.007 | 0.1752 | 0.1688 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0195 | 0.0119 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0037 | 0.071 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0357 | 0.0357 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0037 | 0.071 | 0.0637 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0341 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0071 | 0.0071 |
Onchocerca volvulus | 0.007 | 0.1752 | 0.1589 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0077 | 0.0077 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.1005 | 0.0846 |
Onchocerca volvulus | 0.007 | 0.1752 | 0.1589 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0357 | 0.0295 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1122 | 0.1053 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.