Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0574 | 0.0574 |
Echinococcus multilocularis | geminin | 0.017 | 0.2451 | 0.2451 |
Echinococcus granulosus | carboxylesterase 5A | 0.067 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.1635 | 0.1635 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0113 | 0.159 | 0.159 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Brugia malayi | Carboxylesterase family protein | 0.067 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.067 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0113 | 0.159 | 0.5 |
Onchocerca volvulus | 0.0113 | 0.159 | 0.5 | |
Onchocerca volvulus | 0.0113 | 0.159 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.067 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0113 | 0.159 | 0.159 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0574 | 0.0574 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.1635 | 0.1635 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0113 | 0.159 | 0.159 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.1635 | 0.1635 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0113 | 0.159 | 0.5 |
Echinococcus granulosus | geminin | 0.017 | 0.2451 | 0.2451 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Onchocerca volvulus | 0.0113 | 0.159 | 0.5 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | carboxylesterase | 0.067 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0113 | 0.159 | 0.159 |
Brugia malayi | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0574 | 0.0574 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0574 | 0.0574 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0113 | 0.159 | 0.5 |
Onchocerca volvulus | 0.0113 | 0.159 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0574 | 0.0574 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0113 | 0.159 | 0.159 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0574 | 0.0574 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0574 | 0.0574 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.2451 | 0.2451 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.159 | 0.159 |
Echinococcus granulosus | acetylcholinesterase | 0.067 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.159 | 0.159 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.067 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.067 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.2451 | 0.2451 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0113 | 0.159 | 0.159 |
Echinococcus multilocularis | neuroligin | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.159 | 0.159 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0113 | 0.159 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0113 | 0.159 | 0.159 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0113 | 0.159 | 0.159 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.159 | 0.159 |
Brugia malayi | follicle stimulating hormone receptor | 0.0225 | 0.3284 | 0.3284 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0113 | 0.159 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0574 | 0.0574 |
Onchocerca volvulus | 0.0113 | 0.159 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.159 | 0.159 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0113 | 0.159 | 0.159 |
Echinococcus multilocularis | acetylcholinesterase | 0.067 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0113 | 0.159 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0113 | 0.159 | 0.159 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0574 | 0.0574 |
Schistosoma mansoni | acetylcholinesterase | 0.0113 | 0.159 | 0.159 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0225 | 0.3284 | 0.3284 |
Loa Loa (eye worm) | carboxylesterase | 0.0113 | 0.159 | 0.159 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.