Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.1095 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1479 | 0.4395 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.096 | 0.096 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.3366 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.2866 | 0.2866 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1095 | 0.1095 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1095 | 0.5 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.1095 | 0.3255 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.2979 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.096 | 0.1998 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0066 | 0.2979 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.1095 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.1187 | 0.2673 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1095 | 0.1095 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.096 | 0.0842 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.2979 | 0.2979 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1095 | 0.5 |
Echinococcus multilocularis | geminin | 0.0172 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.1095 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1095 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.1095 | 0.098 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0066 | 0.2979 | 0.2887 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1192 | 0.3541 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0066 | 0.2979 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.2625 | 0.2529 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.3653 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.2979 | 1 |
Brugia malayi | Inositol-1 | 0.0037 | 0.1095 | 0.2401 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.1095 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1028 | 0.0911 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0066 | 0.2979 | 0.2887 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.1095 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0066 | 0.2979 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1028 | 0.0911 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.1095 | 0.098 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.2979 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.096 | 0.096 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1351 | 0.4014 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0128 | 0.0128 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.2625 | 0.2529 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.2979 | 0.2979 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.096 | 0.0842 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0835 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.