Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.1517 | 0.2297 | 0.2297 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0184 | 0.0178 | 0.0476 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0184 | 0.0178 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1075 | 0.1595 | 0.1595 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.1075 | 0.1595 | 0.1595 |
Echinococcus multilocularis | neuroligin | 0.1075 | 0.1595 | 0.1595 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.1075 | 0.1595 | 0.4259 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.1075 | 0.1595 | 0.5 |
Brugia malayi | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0184 | 0.0178 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.6365 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0184 | 0.0178 | 0.0178 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0184 | 0.0178 | 0.5 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0184 | 0.0178 | 0.0178 |
Schistosoma mansoni | amine oxidase | 0.0184 | 0.0178 | 0.0178 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0184 | 0.0178 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.1075 | 0.1595 | 0.3671 |
Schistosoma mansoni | acetylcholinesterase | 0.1075 | 0.1595 | 0.1595 |
Schistosoma mansoni | amine oxidase | 0.0184 | 0.0178 | 0.0178 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0184 | 0.0178 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.6365 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.6365 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.6365 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.6365 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.6365 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0184 | 0.0178 | 0.0476 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0184 | 0.0178 | 0.0178 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.1075 | 0.1595 | 0.1595 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0184 | 0.0178 | 0.0178 |
Onchocerca volvulus | 0.1075 | 0.1595 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.6365 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0254 | 0.029 | 0.029 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0184 | 0.0178 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0184 | 0.0178 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Onchocerca volvulus | 0.1075 | 0.1595 | 1 | |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0184 | 0.0178 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0184 | 0.0178 | 1 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0184 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | carboxylesterase | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0815 | 0.1181 | 0.1181 |
Schistosoma mansoni | gliotactin | 0.1075 | 0.1595 | 0.1595 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.1075 | 0.1595 | 0.4259 |
Echinococcus granulosus | BC026374 protein S09 family | 0.1075 | 0.1595 | 0.1595 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0184 | 0.0178 | 1 |
Echinococcus granulosus | neuroligin | 0.1075 | 0.1595 | 0.1595 |
Plasmodium vivax | hypothetical protein, conserved | 0.0184 | 0.0178 | 1 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0702 | 0.1002 | 0.1002 |
Brugia malayi | Carboxylesterase family protein | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.2429 | 0.3745 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.2612 | 0.4037 | 1 |
Onchocerca volvulus | 0.1075 | 0.1595 | 1 | |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0184 | 0.0178 | 0.0178 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0184 | 0.0178 | 1 |
Brugia malayi | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Brugia malayi | Carboxylesterase family protein | 0.1075 | 0.1595 | 0.1595 |
Echinococcus multilocularis | carboxylesterase 5A | 0.6365 | 1 | 1 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0184 | 0.0178 | 0.0178 |
Plasmodium vivax | hypothetical protein, conserved | 0.0184 | 0.0178 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.6365 | 1 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0072 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.1075 | 0.1595 | 0.4259 |
Brugia malayi | Carboxylesterase family protein | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0254 | 0.029 | 0.029 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.1075 | 0.1595 | 0.1595 |
Onchocerca volvulus | 0.1075 | 0.1595 | 1 | |
Echinococcus granulosus | acetylcholinesterase | 0.6365 | 1 | 1 |
Brugia malayi | SWIRM domain containing protein | 0.0184 | 0.0178 | 0.0178 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.2612 | 0.4037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Echinococcus multilocularis | 0.0184 | 0.0178 | 0.0178 | |
Leishmania major | UDP-galactopyranose mutase | 0.0184 | 0.0178 | 1 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.1926 | 0.2946 | 0.2946 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Onchocerca volvulus | 0.1075 | 0.1595 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.0533 | 0.0533 |
Brugia malayi | Carboxylesterase family protein | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 0.1595 | 0.1595 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.6365 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.1075 | 0.1595 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0178 | 0.0178 |
Echinococcus granulosus | acetylcholinesterase | 0.6365 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.