Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Toxoplasma gondii | thioredoxin reductase | 0.0089 | 0.0105 | 0.5297 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0077 | 0.0089 | 0.0403 |
Plasmodium falciparum | plasmepsin VII | 0.0152 | 0.0195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0017 | 0.0017 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0089 | 0.0105 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0044 | 0.0044 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0034 | 0.0027 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Brugia malayi | Thioredoxin reductase | 0.0089 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.008 | 0.0077 |
Onchocerca volvulus | 0.1187 | 0.1672 | 1 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0044 | 0.004 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0046 | 0.0044 | 0.0041 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0044 | 0.004 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0074 | 0.0084 | 0.0374 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.0089 | 0.8167 |
Onchocerca volvulus | 0.0077 | 0.0089 | 0.0426 | |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0034 | 0.0027 | 0.0708 |
Echinococcus multilocularis | neuroligin | 0.1187 | 0.1672 | 0.1669 |
Loa Loa (eye worm) | carboxylesterase | 0.7027 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0133 | 0.0169 | 0.0169 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0605 | 0.0841 | 0.4965 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0046 | 0.0044 | 0.0131 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.0089 | 0.0423 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.0089 | 0.8167 |
Brugia malayi | Pepsin A precursor | 0.0152 | 0.0195 | 0.0195 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0036 | 0.0036 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0031 | 0.0023 | 0.0019 |
Plasmodium falciparum | plasmepsin X | 0.0152 | 0.0195 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Mycobacterium ulcerans | monoamine oxidase | 0.0046 | 0.0044 | 0.0131 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0036 | 0.0101 |
Plasmodium vivax | hypothetical protein, conserved | 0.0046 | 0.0044 | 0.2115 |
Brugia malayi | Carboxylesterase family protein | 0.1187 | 0.1672 | 0.1672 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0031 | 0.0023 | 0.0987 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0046 | 0.0044 | 0.0041 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.0089 | 0.0403 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0152 | 0.0195 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0046 | 0.0044 | 0.0044 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0031 | 0.0023 | 0.0602 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0004 | 0.0004 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0077 | 0.0089 | 0.0403 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0027 | 0.0024 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0152 | 0.0195 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0032 | 0.0028 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0017 | 0.071 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0152 | 0.0195 | 0.0195 |
Onchocerca volvulus | 0.1187 | 0.1672 | 1 | |
Mycobacterium ulcerans | dehydrogenase | 0.0046 | 0.0044 | 0.0131 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0044 | 0.0044 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0031 | 0.0023 | 0.0602 |
Echinococcus multilocularis | geminin | 0.0173 | 0.0225 | 0.0221 |
Onchocerca volvulus | 0.0152 | 0.0195 | 0.1068 | |
Plasmodium falciparum | plasmepsin IV | 0.0152 | 0.0195 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0018 | 0.0018 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.0089 | 0.0085 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0027 | 0.0053 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0077 | 0.0089 | 0.0403 |
Brugia malayi | TAR-binding protein | 0.0133 | 0.0169 | 0.0169 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0074 | 0.0084 | 0.0394 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Echinococcus multilocularis | acetylcholinesterase | 0.7027 | 1 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0077 | 0.0089 | 0.0403 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0027 | 0.0024 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.004 | 0.0131 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0034 | 0.0027 | 0.1138 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.0089 | 0.0403 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Loa Loa (eye worm) | glutathione reductase | 0.0089 | 0.0105 | 0.0105 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0034 | 0.0027 | 0.0028 |
Echinococcus multilocularis | tar DNA binding protein | 0.0133 | 0.0169 | 0.0165 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.0089 | 0.0423 |
Leishmania major | pyruvate kinase | 0.0034 | 0.0027 | 0.1138 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0027 | 0.0027 |
Plasmodium vivax | pyruvate kinase, putative | 0.0034 | 0.0027 | 0.1232 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0023 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0169 | 0.0165 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0046 | 0.0044 | 0.2115 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.0027 | 0.1138 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0089 | 0.0105 | 0.0101 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0077 | 0.0089 | 0.0403 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0152 | 0.0195 | 0.0191 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0046 | 0.0044 | 0.0131 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0152 | 0.0195 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 0.0018 | 0.0015 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0046 | 0.0044 | 0.2115 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0152 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0152 | 0.0195 | 0.0195 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0017 | 0.071 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0046 | 0.0044 | 0.0041 |
Mycobacterium ulcerans | hypothetical protein | 0.0077 | 0.0089 | 0.0403 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0032 | 0.2664 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0077 | 0.0089 | 0.0403 |
Echinococcus granulosus | acetylcholinesterase | 0.7027 | 1 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0152 | 0.0195 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0066 | 0.0073 | 0.763 |
Plasmodium falciparum | plasmepsin II | 0.0152 | 0.0195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0027 | 0.0053 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 0.0161 | 0.0161 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.0089 | 0.0089 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0034 | 0.0027 | 0.1138 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.7027 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.7027 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0084 | 0.7634 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Mycobacterium leprae | Probable lipase LipE | 0.0077 | 0.0089 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0023 | 0.0011 | 0.0011 |
Plasmodium vivax | aspartyl protease, putative | 0.0152 | 0.0195 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.008 | 0.0077 |
Trypanosoma brucei | trypanothione reductase | 0.0089 | 0.0105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0089 | 0.0089 |
Schistosoma mansoni | gliotactin | 0.1187 | 0.1672 | 0.1669 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0018 | 0.0018 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.1187 | 0.1672 | 1 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0152 | 0.0195 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0074 | 0.0084 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0089 | 0.0089 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0046 | 0.0044 | 0.3063 |
Plasmodium falciparum | plasmepsin I | 0.0152 | 0.0195 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0066 | 0.0073 | 0.0307 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0031 | 0.0023 | 0.0602 |
Plasmodium falciparum | glutathione reductase | 0.0031 | 0.0023 | 0.0987 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0023 | 0.0011 | 0.0011 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0046 | 0.0044 | 0.0131 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0034 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.0031 | 0.0023 | 0.003 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.1187 | 0.1672 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0046 | 0.0044 | 0.2115 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0018 | 0.0015 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0169 | 0.0165 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.0225 | 0.0221 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0044 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Echinococcus multilocularis | pyruvate kinase | 0.0027 | 0.0017 | 0.0013 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0036 | 0.0104 |
Echinococcus granulosus | carboxylesterase 5A | 0.7027 | 1 | 1 |
Onchocerca volvulus | 0.0152 | 0.0195 | 0.1068 | |
Echinococcus granulosus | neuroligin | 0.1187 | 0.1672 | 0.1669 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.7027 | 1 | 1 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | acetylcholinesterase | 0.7027 | 1 | 1 |
Onchocerca volvulus | 0.005 | 0.005 | 0.0189 | |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0018 | 0.0015 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0031 | 0.0023 | 0.0987 |
Brugia malayi | Carboxylesterase family protein | 0.7027 | 1 | 1 |
Onchocerca volvulus | 0.1187 | 0.1672 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0133 | 0.0169 | 0.0169 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.3869 |
Leishmania major | pyruvate kinase | 0.0034 | 0.0027 | 0.1138 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0089 | 0.0089 |
Mycobacterium ulcerans | beta-lactamase | 0.0077 | 0.0089 | 0.0403 |
Onchocerca volvulus | 0.1187 | 0.1672 | 1 | |
Plasmodium vivax | plasmepsin V, putative | 0.0152 | 0.0195 | 1 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.3776 | 0.5364 | 0.5362 |
Brugia malayi | Inositol-1 | 0.0074 | 0.0084 | 0.0084 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.008 | 0.037 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0046 | 0.0044 | 1 |
Giardia lamblia | Pyruvate kinase | 0.0034 | 0.0027 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0031 | 0.0023 | 0.8007 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.004 | 0.0127 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0027 | 0.0024 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0074 | 0.0084 | 0.0394 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0152 | 0.0195 | 0.0195 |
Brugia malayi | Carboxylesterase family protein | 0.1187 | 0.1672 | 0.1672 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0195 | 0.0195 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.1187 | 0.1672 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.005 | 0.0046 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0032 | 0.0028 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.0027 | 0.1138 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0044 | 0.004 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0077 | 0.0089 | 0.0403 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.0225 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.1187 | 0.1672 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.005 | 0.0046 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0152 | 0.0195 | 0.0191 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0152 | 0.0195 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1187 | 0.1672 | 0.1672 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0032 | 0.0028 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.008 | 0.037 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0027 | 0.0027 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0032 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0195 | 0.0195 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0074 | 0.0084 | 0.0081 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0046 | 0.0044 | 0.3253 |
Schistosoma mansoni | lamin | 0.0028 | 0.0018 | 0.0015 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0651 | 0.0907 | 0.5361 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0032 | 0.2664 |
Toxoplasma gondii | ABC1 family protein | 0.0077 | 0.0089 | 0.4457 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.004 | 0.0127 |
Onchocerca volvulus | 0.0077 | 0.0089 | 0.0426 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0077 | 0.0089 | 0.0403 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0074 | 0.0084 | 1 |
Brugia malayi | hypothetical protein | 0.0152 | 0.0195 | 0.0195 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.0089 | 0.0423 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.008 | 0.0077 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0031 | 0.0023 | 0.0987 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0017 | 0.0017 |
Leishmania major | trypanothione reductase | 0.0089 | 0.0105 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.008 | 0.008 |
Plasmodium falciparum | plasmepsin V | 0.0152 | 0.0195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0089 | 0.0089 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.008 | 0.0077 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0152 | 0.0195 | 0.1065 |
Plasmodium falciparum | plasmepsin VI | 0.0152 | 0.0195 | 1 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0046 | 0.0044 | 0.2115 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0027 | 0.0027 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0018 | 0.0015 |
Echinococcus granulosus | geminin | 0.0173 | 0.0225 | 0.0221 |
Loa Loa (eye worm) | beta-lactamase | 0.0077 | 0.0089 | 0.0089 |
Plasmodium vivax | aspartyl protease, putative | 0.0152 | 0.0195 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.7027 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.0089 | 0.0085 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0152 | 0.0195 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0133 | 0.0169 | 0.0169 |
Brugia malayi | glutathione reductase | 0.0089 | 0.0105 | 0.0105 |
Echinococcus granulosus | BC026374 protein S09 family | 0.1187 | 0.1672 | 0.1669 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0046 | 0.0044 | 0.2115 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.1187 | 0.1672 | 0.1669 |
Brugia malayi | MH2 domain containing protein | 0.0128 | 0.0161 | 0.0161 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0031 | 0.0023 | 0.0602 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.008 | 0.008 |
Plasmodium falciparum | glutathione reductase | 0.0089 | 0.0105 | 0.5297 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0027 | 0.0024 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.1187 | 0.1672 | 0.1669 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0044 | 0.004 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0046 | 0.0044 | 0.2115 |
Brugia malayi | Carboxylesterase family protein | 0.1187 | 0.1672 | 0.1672 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0195 | 0.0195 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0036 | 0.0101 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0077 | 0.0089 | 0.0085 |
Plasmodium falciparum | thioredoxin reductase | 0.0031 | 0.0023 | 0.0987 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0027 | 0.0024 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0027 | 0.0053 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0074 | 0.0084 | 0.0394 |
Brugia malayi | SWIRM domain containing protein | 0.0046 | 0.0044 | 0.0044 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.0089 | 0.8167 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.0078 | 0.0074 |
Brugia malayi | hypothetical protein | 0.0152 | 0.0195 | 0.0195 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0244 | 0.0326 | 0.0323 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0018 | 0.0018 |
Schistosoma mansoni | amine oxidase | 0.0046 | 0.0044 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0077 | 0.0089 | 0.0089 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.0334 |
Plasmodium vivax | glutathione reductase, putative | 0.0089 | 0.0105 | 0.5297 |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.0334 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0031 | 0.0023 | 0.0023 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.008 | 0.0077 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Loa Loa (eye worm) | carboxylesterase | 0.1187 | 0.1672 | 0.1672 |
Mycobacterium ulcerans | pyruvate kinase | 0.0034 | 0.0027 | 0.0028 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0032 | 0.2664 |
Echinococcus granulosus | lamin | 0.0028 | 0.0018 | 0.0015 |
Plasmodium falciparum | thioredoxin reductase | 0.0089 | 0.0105 | 0.5297 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0027 | 0.0024 |
Brugia malayi | Carboxylesterase family protein | 0.1187 | 0.1672 | 0.1672 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.0326 | 0.0326 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.1187 | 0.1672 | 0.1669 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0152 | 0.0195 | 0.0195 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0084 | 0.7634 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.0334 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0031 | 0.0023 | 0.0021 |
Schistosoma mansoni | inositol monophosphatase | 0.0074 | 0.0084 | 0.0081 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0046 | 0.0044 | 0.2115 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0044 | 0.004 |
Schistosoma mansoni | acetylcholinesterase | 0.1187 | 0.1672 | 0.1669 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0018 | 0.0018 |
Brugia malayi | beta-lactamase | 0.0077 | 0.0089 | 0.0089 |
Brugia malayi | hypothetical protein | 0.0244 | 0.0326 | 0.0326 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 0.0161 | 0.0161 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.0089 | 0.4457 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0089 | 0.0105 | 0.05 |
Echinococcus granulosus | tar DNA binding protein | 0.0133 | 0.0169 | 0.0165 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0031 | 0.0023 | 0.0987 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0031 | 0.0023 | 0.0602 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.0089 | 0.0403 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.0089 | 0.0423 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.005 | 0.005 |
Plasmodium vivax | plasmepsin IV, putative | 0.0152 | 0.0195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0036 | 0.0036 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0031 | 0.0023 | 0.0019 |
Schistosoma mansoni | amine oxidase | 0.0046 | 0.0044 | 0.0041 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0034 | 0.0027 | 0.0049 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0225 | 0.03 | 0.03 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0074 | 0.0084 | 0.4212 |
Onchocerca volvulus | 0.0046 | 0.0044 | 0.0155 | |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0031 | 0.0023 | 0.0987 |
Leishmania major | UDP-galactopyranose mutase | 0.0046 | 0.0044 | 0.3063 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0046 | 0.0044 | 0.0041 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0074 | 0.0084 | 1 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0152 | 0.0195 | 0.0195 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0031 | 0.0023 | 0.0987 |
Brugia malayi | RNA binding protein | 0.0133 | 0.0169 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.7027 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.7027 | 1 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0031 | 0.0023 | 0.0021 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.0074 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0074 | 0.0084 | 0.0081 |
Trichomonas vaginalis | esterase, putative | 0.0077 | 0.0089 | 0.0423 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0034 | 0.0027 | 0.1232 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0034 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | inositol-1 | 0.0074 | 0.0084 | 0.0084 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0032 | 0.2664 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.008 | 0.0077 |
Mycobacterium leprae | conserved hypothetical protein | 0.0077 | 0.0089 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0084 | 0.7634 |
Treponema pallidum | NADH oxidase | 0.0031 | 0.0023 | 0.5 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0031 | 0.0023 | 0.0602 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0046 | 0.0044 | 0.0041 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.1187 | 0.1672 | 0.1669 |
Chlamydia trachomatis | pyruvate kinase | 0.0034 | 0.0027 | 0.2175 |
Plasmodium falciparum | plasmepsin III | 0.0152 | 0.0195 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0225 | 0.03 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0089 | 0.0089 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0046 | 0.0044 | 0.2115 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0089 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0031 | 0.0023 | 0.0602 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0017 | 0.071 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0084 | 0.7634 |
Mycobacterium ulcerans | oxidoreductase | 0.0046 | 0.0044 | 0.0131 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0169 | 0.0165 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0169 | 0.0165 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0089 | 0.0105 | 0.5297 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.0078 | 0.0074 |
Plasmodium falciparum | plasmepsin IX | 0.0152 | 0.0195 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.0169 | 0.0165 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0018 | 0.0015 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0077 | 0.0089 | 0.0085 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0244 | 0.0326 | 0.0323 |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0017 | 0.071 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Echinococcus multilocularis | 0.0046 | 0.0044 | 0.0041 | |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0651 | 0.0907 | 0.5361 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0046 | 0.0044 | 0.3063 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.1187 | 0.1672 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0044 | 0.004 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0077 | 0.0089 | 0.0403 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.1187 | 0.1672 | 1 |
Plasmodium falciparum | pyruvate kinase | 0.0034 | 0.0027 | 0.1232 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0152 | 0.0195 | 0.0191 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0089 | 0.0105 | 0.0101 |
Loa Loa (eye worm) | RNA binding protein | 0.0133 | 0.0169 | 0.0169 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0089 | 0.0089 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.0078 | 0.6886 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0046 | 0.0044 | 0.0041 |
Brugia malayi | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0031 | 0.0023 | 0.0019 |
Onchocerca volvulus | 0.0077 | 0.0089 | 0.0426 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.0089 | 0.0423 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0494 | 0.0683 | 0.4002 |
Toxoplasma gondii | aspartyl protease | 0.0152 | 0.0195 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0077 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.1187 | 0.1672 | 0.1672 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.0089 | 0.0089 |
Plasmodium vivax | aspartyl protease, putative | 0.0152 | 0.0195 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0023 | 0.0602 |
Mycobacterium ulcerans | lipase LipD | 0.0077 | 0.0089 | 0.0403 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.0089 | 0.8167 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0078 | 0.0334 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.1187 | 0.1672 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.